Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

Free Radical Biology and Medicine

Volumn 51, Issue 5, 2011, Pages 1035-1053

  Batinic Haberle, Ines ^a   Rajic, Zrinka ^a,e   Tovmasyan, Artak ^a   Reboucas, Julio S ^b   Ye, Xiaodong ^c,f   Leong, Kam W ^c   Dewhirst, Mark W ^a   Vujaskovic, Zeljko ^a   Benov, Ludmil ^d   Spasojevic, Ivan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c Duke University   (United States)

^d KUWAIT UNIVERSITY   (Kuwait)

^e UNIVERSITY OF ZAGREB   (Croatia)

^f UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

AEOL10113; AEOL10150; Antioxidants; Mn porphyrins; MnTDE 2 ImP 5+; MnTE 2 PyP 5+; MnTnHex 2 PyP 5+; Oxidative stress; Peroxynitrite scavengers; Pro oxidants; Reactive species; SOD mimics

Indexed keywords

ANTIOXIDANT; MANGANESE DERIVATIVE; NUCLEIC ACID; PEROXYNITRITE; PORPHYRIN DERIVATIVE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

BLOOD BRAIN BARRIER; CELL FUNCTION; DRUG BIOAVAILABILITY; ESCHERICHIA COLI; HUMAN; HYDROPHILICITY; IN VIVO STUDY; INTRAOCULAR HYPERTENSION; ISCHEMIA; LIPOPHILICITY; LUNG INJURY; MAXIMUM PLASMA CONCENTRATION; MITOCHONDRION; NEOPLASM; NERVOUS SYSTEM INJURY; NONHUMAN; OXIDATIVE STRESS; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN INTERACTION; RADIATION INJURY; RADIATION PROTECTION; REPERFUSION INJURY; REVIEW; SACCHAROMYCES CEREVISIAE; SEPSIS; SICKLE CELL ANEMIA; SPERMATOZOON MOTILITY; THERMODYNAMICS; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTIOXIDANTS; BIOMIMETICS; BRAIN INJURIES; CLINICAL TRIALS AS TOPIC; HEMATOPORPHYRINS; HUMANS; METALLOPORPHYRINS; NEOPLASMS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

AEOLUS; ANIMALIA; PRIMATES;

EID: 79958144635     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.04.046     Document Type: Review

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