High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli

Journal of Medicinal Chemistry

Volumn 52, Issue 23, 2009, Pages 7868-7872

  Kos, Ivan ^a,c   Benov, Ludmil ^b   Spasojević, Ivan ^a   Rebouças, Júlio S ^a,d   Batinić Haberle, Ines ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KUWAIT UNIVERSITY   (Kuwait)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; PORPHYRIN DERIVATIVE; SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG POTENCY; ESCHERICHIA COLI; ISOMER; LIPOPHILICITY; MOLECULAR MIMICRY; NONHUMAN; OXIDATIVE STRESS; PROTECTION;

AEROBIOSIS; ANTIOXIDANTS; BIOMIMETIC MATERIALS; CYTOSOL; ESCHERICHIA COLI; HYDROPHOBICITY; ISOMERISM; MANGANESE; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; PORPHYRINS; SUPEROXIDE DISMUTASE;

EID: 72249085979     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900576g     Document Type: Article

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