Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP5+, in plasma and major organs of B6C3F1 mice

Free Radical Biology and Medicine

Volumn 45, Issue 7, 2008, Pages 943-949

  Spasojević, Ivan ^a   Chen, Yumin ^b   Noel, Teresa J ^b   Fan, Ping ^a   Zhang, Lichun ^a   Rebouças, Julio S ^a   St Clair, Daret K ^b   Batinić Haberle, Ines ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

AEOL 10113; Free radicals; MnTE 2 PyP5+; Pharmacokinetics in mouse organs; Pharmacokinetics in mouse plasma; Pharmacokinetics in mouse tissues; SOD mimic

Indexed keywords

MANGANESE DERIVATIVE; MANGANESE TETRAKIS(N ETHYLPYRIDINIUM 2 YL)PORPHYRIN; PEROXYNITRITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; MAXIMUM PLASMA CONCENTRATION; MITOCHONDRION; MOUSE; NONHUMAN; ORGAN DISTRIBUTION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTIOXIDANTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; METALLOPORPHYRINS; MICE; OXIDATION-REDUCTION; TISSUE DISTRIBUTION;

MUS;

EID: 51349159134     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.05.015     Document Type: Article

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