Role of nitroso radicals as drug targets in circulatory shock

British Journal of Pharmacology

Volumn 157, Issue 4, 2009, Pages 494-508

  Esposito, Emanuela ^a,b   Cuzzocrea, Salvátore ^a,c  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Hydroxyl radical; Ischaemia reperfusion injury; Peroxynitrite; Shock; Superoxide; Superoxide dismutase

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIOXIDANT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; FREE RADICAL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; M 40401; MANGANESE DERIVATIVE; MANGANESEDICHLORO(3,10,13,20,26 PENTAAZATETRACYCLO[20.3.1.0(4,9).0(14,19)] 1(26),22(23),24 HEXACOSATRIENE); NITROSO DERIVATIVE; PEROXYNITRITE; SC 55858; SODIUM CHANNEL; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VASOACTIVE AGENT; METALLOPORPHYRIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ACUTE LUNG INJURY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; BLOOD PRESSURE; BLOOD VESSEL INJURY; CARDIOVASCULAR AUTOREGULATION; CATALYST; CELL METABOLISM; CELL PROTECTION; CHEMICAL BOND; CONCENTRATION RESPONSE; CORONARY ARTERY BLOOD FLOW; DECOMPOSITION; DISEASE SEVERITY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG TARGETING; ENDOTHELIAL DYSFUNCTION; EX VIVO STUDY; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART OUTPUT; HUMAN; HYPOXEMIA; IMMUNOREACTIVITY; ISOMERIZATION; KIDNEY CORTEX; LEUKOCYTE ADHERENCE; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; NITRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REVIEW; SEPTIC SHOCK; SHOCK; THORACIC AORTA; VASCULAR ENDOTHELIUM; ANIMAL; BIOLOGICAL MODEL; CARDIOGENIC SHOCK; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DELIVERY SYSTEM; METABOLISM; PHYSIOLOGY; REPERFUSION INJURY;

ANIMALS; ANTIOXIDANTS; DRUG DELIVERY SYSTEMS; HUMANS; METALLOPORPHYRINS; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SHOCK, CARDIOGENIC; SUPEROXIDE DISMUTASE;

EID: 70349921196     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00255.x     Document Type: Review

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