Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(iii) N-methoxyalkylpyridylporphyrins

Dalton Transactions

Volumn 40, Issue 16, 2011, Pages 4111-4121

  Tovmasyan, Artak G ^a   Rajic, Zrinka ^a   Spasojevic, Ivan ^a   Reboucas, Julio S ^b   Chen, Xin ^c,f   Salvemini, Daniela ^d   Sheng, Huaxin ^a   Warner, David S ^a   Benov, Ludmil ^e   Batinic Haberle, Ines ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c DUKE UNIVERSITY   (United States)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e KUWAIT UNIVERSITY   (Kuwait)

^f CHANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC GROWTH; ALKYL CHAIN; ALKYL SUBSTITUENT; ANIMAL MODEL; BENEFICIAL EFFECTS; BLOOD-BRAIN BARRIER; CELL WALLS; CENTRAL NERVOUS SYSTEMS; CHROMATOGRAPHIC RETENTION; CYTOSOLS; DERIVATIZATIONS; E. COLI; ELEMENTAL ANALYSIS; IN-VIVO; LIPOPHILICITY; META ISOMERS; METHOXY; METHOXY GROUP; ORTHO ISOMERS; PEROXYNITRITES; PYRIDINIUM; PYRIDYL; PYRIDYL RINGS; REDOX COUPLE; REDUCTION POTENTIAL; ROTATIONAL FLEXIBILITY; SUPEROXIDES; TETRAKIS; THIN LAYERS; UV-VIS SPECTROSCOPY;

ALKYLATION; BIOCHEMISTRY; ESCHERICHIA COLI; ISOMERS; MASS SPECTROMETRY; OXYGEN; PORPHYRINS; TOXICITY; ULTRAVIOLET SPECTROSCOPY;

MANGANESE;

ASCORBIC ACID; BIOMIMETIC MATERIAL; MANGANESE; METALLOPORPHYRIN; SUPEROXIDE DISMUTASE;

ARTICLE; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECT; ELECTROCHEMISTRY; ENZYMOLOGY; ESCHERICHIA COLI; ISOMERISM; METABOLISM; OXIDATION REDUCTION REACTION; SYNTHESIS;

ASCORBIC ACID; BIOMIMETIC MATERIALS; ELECTROCHEMISTRY; ESCHERICHIA COLI; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOMERISM; MANGANESE; METALLOPORPHYRINS; OXIDATION-REDUCTION; SUPEROXIDE DISMUTASE;

EID: 79953763716     PISSN: 14779226     EISSN: 14779234     Source Type: Journal    
DOI: 10.1039/c0dt01321h     Document Type: Article

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