Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na+/H+ exchangers NHE-1 and NHE-3 in the diabetic rat

Redox Report

Volumn 14, Issue 6, 2009, Pages 236-242

  Khan, Islam ^a   Batinic Haberle, Ines ^b   Benov, Ludmil T ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antioxidant; Diabetes; Diabetic complications; Diabetic nephropathy; Hyperglycemia; Manganese porphyrin; Mntm 2 pyp; Na + h+ exchanger (nhe); Oxidative stress; Sod mimic

Indexed keywords

3 NITROTYROSINE; ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); GLUCOSE; GLYCOSYLATED HEMOGLOBIN; LIPID; MANGANESE 5,10,15,20 TETRAKIS(N METHYLPYRIDINIUM 2 YL)PORPHYRIN; PORPHYRIN DERIVATIVE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INACTIVATION; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; KIDNEY HOMOGENATE; KIDNEY MICROSOME; KIDNEY PARENCHYMA; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; TRANSCRIPTION REGULATION;

ACONITATE HYDRATASE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; FUMARATE HYDRATASE; HEMOGLOBIN A, GLYCOSYLATED; KIDNEY; LIPID PEROXIDATION; MALE; METALLOPORPHYRINS; OXIDATION-REDUCTION; RANDOM ALLOCATION; RATS; RATS, WISTAR; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 73949101995     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/135100009X12525712409698     Document Type: Article

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