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Volumn 340, Issue 1, 2011, Pages 35-43

Ghrelin in gastrointestinal disease

Author keywords

Cachexia; Coeliac disease; Gastritis; Gastrointestinal; Ghrelin; GOAT; H. pylori; IBD; MCT; Motility

Indexed keywords

ACYLTRANSFERASE; C REACTIVE PROTEIN; GHRELIN; GHRELIN O ACYLTRANSFERASE; GROWTH HORMONE SECRETAGOGUE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; ULIMORELIN; UNCLASSIFIED DRUG;

EID: 79958142841     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2011.03.002     Document Type: Review
Times cited : (13)

References (155)
  • 1
    • 77958123533 scopus 로고    scopus 로고
    • Histamine H receptors are involved in the protective effect of ghrelin against HCl-induced gastric damage in rats
    • Adami M., Pozzoli C., Leurs R., Stark H., Coruzzi G. Histamine H receptors are involved in the protective effect of ghrelin against HCl-induced gastric damage in rats. Pharmacology 2010, 86:259-266.
    • (2010) Pharmacology , vol.86 , pp. 259-266
    • Adami, M.1    Pozzoli, C.2    Leurs, R.3    Stark, H.4    Coruzzi, G.5
  • 7
    • 68149165610 scopus 로고    scopus 로고
    • Effect of octanoic acid-rich formula on plasma ghrelin levels in cachectic patients with chronic respiratory disease
    • Ashitani J., Matsumoto N., Nakazato M. Effect of octanoic acid-rich formula on plasma ghrelin levels in cachectic patients with chronic respiratory disease. Nutr. J. 2009, 8:25.
    • (2009) Nutr. J. , vol.8 , pp. 25
    • Ashitani, J.1    Matsumoto, N.2    Nakazato, M.3
  • 8
    • 46449130662 scopus 로고    scopus 로고
    • Serum ghrelin levels in inflammatory bowel disease with relation to disease activity and nutritional status
    • Ates Y., Degertekin B., Erdil A., Yaman H., Dagalp K. Serum ghrelin levels in inflammatory bowel disease with relation to disease activity and nutritional status. Dig. Dis. Sci. 2008, 53:2215-2221.
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 2215-2221
    • Ates, Y.1    Degertekin, B.2    Erdil, A.3    Yaman, H.4    Dagalp, K.5
  • 9
    • 29044448053 scopus 로고    scopus 로고
    • Ghrelin immunohistochemistry of gastric adenocarcinoma and mucoepidermoid carcinoma of salivary gland
    • Aydin S., Ozercan I.H., Dagli F., Dogru O., Celebi S., Akin O., Guzel S.P. Ghrelin immunohistochemistry of gastric adenocarcinoma and mucoepidermoid carcinoma of salivary gland. Biotech. Histochem. 2005, 80:163-168.
    • (2005) Biotech. Histochem. , vol.80 , pp. 163-168
    • Aydin, S.1    Ozercan, I.H.2    Dagli, F.3    Dogru, O.4    Celebi, S.5    Akin, O.6    Guzel, S.P.7
  • 10
    • 0035077955 scopus 로고    scopus 로고
    • Growth failure and intestinal inflammation
    • Ballinger A.B., Camacho-Hubner C., Croft N.M. Growth failure and intestinal inflammation. QJM 2001, 94:121-125.
    • (2001) QJM , vol.94 , pp. 121-125
    • Ballinger, A.B.1    Camacho-Hubner, C.2    Croft, N.M.3
  • 11
    • 0031873543 scopus 로고    scopus 로고
    • Level of chronic life stress predicts clinical outcome in irritable bowel syndrome
    • Bennett E.J., Tennant C.C., Piesse C., Badcock C.A., Kellow J.E. Level of chronic life stress predicts clinical outcome in irritable bowel syndrome. Gut 1998, 43:256-261.
    • (1998) Gut , vol.43 , pp. 256-261
    • Bennett, E.J.1    Tennant, C.C.2    Piesse, C.3    Badcock, C.A.4    Kellow, J.E.5
  • 17
    • 3442886801 scopus 로고    scopus 로고
    • Celiac disease as a cause of growth retardation in childhood
    • Catassi C., Fasano A. Celiac disease as a cause of growth retardation in childhood. Curr. Opin. Pediatr. 2004, 16:445-449.
    • (2004) Curr. Opin. Pediatr. , vol.16 , pp. 445-449
    • Catassi, C.1    Fasano, A.2
  • 20
    • 0031879649 scopus 로고    scopus 로고
    • The gastric H+, K+: ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy
    • Claeys D., Faller G., Appelmelk B.J., Negrini R., Kirchner T. The gastric H+, K+: ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy. Gastroenterology 1998, 115:340-347.
    • (1998) Gastroenterology , vol.115 , pp. 340-347
    • Claeys, D.1    Faller, G.2    Appelmelk, B.J.3    Negrini, R.4    Kirchner, T.5
  • 21
    • 0038298292 scopus 로고    scopus 로고
    • Circulating ghrelin levels in patients with pancreatic and gastrointestinal neuroendocrine tumors: identification of one pancreatic ghrelinoma
    • Corbetta S., Peracchi M., Cappiello V., Lania A., Lauri E., Vago L., Beck-Peccoz P., Spada A. Circulating ghrelin levels in patients with pancreatic and gastrointestinal neuroendocrine tumors: identification of one pancreatic ghrelinoma. J. Clin. Endocrinol. Metab. 2003, 88:3117-3120.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 3117-3120
    • Corbetta, S.1    Peracchi, M.2    Cappiello, V.3    Lania, A.4    Lauri, E.5    Vago, L.6    Beck-Peccoz, P.7    Spada, A.8
  • 22
    • 53249115190 scopus 로고    scopus 로고
    • Mucosal immunology down under: Special Interest Group in Mucosal Immunology workshop, Australasian Society for Immunology, Sydney, Australia, 2 December 2007
    • Cripps A.W., Sutton P., Beagley K., Robertson S., Dunkley M. Mucosal immunology down under: Special Interest Group in Mucosal Immunology workshop, Australasian Society for Immunology, Sydney, Australia, 2 December 2007. Immunol. Cell Biol. 2008, 86:557-561.
    • (2008) Immunol. Cell Biol. , vol.86 , pp. 557-561
    • Cripps, A.W.1    Sutton, P.2    Beagley, K.3    Robertson, S.4    Dunkley, M.5
  • 24
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 26
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date Y., Kojima M., Hosoda H., Sawaguchi A., Mondal M.S., Suganuma T., Matsukura S., Kangawa K., Nakazato M. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000, 141:4255-4261.
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5    Suganuma, T.6    Matsukura, S.7    Kangawa, K.8    Nakazato, M.9
  • 29
    • 67149122307 scopus 로고    scopus 로고
    • Motilin and ghrelin as prokinetic drug targets
    • De Smet B., Mitselos A., Depoortere I. Motilin and ghrelin as prokinetic drug targets. Pharmacol. Ther. 2009, 123:207-223.
    • (2009) Pharmacol. Ther. , vol.123 , pp. 207-223
    • De Smet, B.1    Mitselos, A.2    Depoortere, I.3
  • 33
    • 44949220043 scopus 로고    scopus 로고
    • Non-invasive tests in gastric diseases
    • di Mario F., Cavallaro L.G. Non-invasive tests in gastric diseases. Dig. Liver Dis. 2008, 40:523-530.
    • (2008) Dig. Liver Dis. , vol.40 , pp. 523-530
    • di Mario, F.1    Cavallaro, L.G.2
  • 36
    • 67149146799 scopus 로고    scopus 로고
    • Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation
    • Dixit V.D., Yang H., Cooper-Jenkins A., Giri B.B., Patel K., Taub D.D. Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation. Blood 2009, 113:5202-5205.
    • (2009) Blood , vol.113 , pp. 5202-5205
    • Dixit, V.D.1    Yang, H.2    Cooper-Jenkins, A.3    Giri, B.B.4    Patel, K.5    Taub, D.D.6
  • 41
    • 78649330100 scopus 로고    scopus 로고
    • Abnormal small-intestinal endocrine cells in patients with irritable bowel syndrome
    • El-Salhy M., Vaali K., Dizdar V., Hausken T. Abnormal small-intestinal endocrine cells in patients with irritable bowel syndrome. Dig. Dis. Sci. 2010, 55:3508-3513.
    • (2010) Dig. Dis. Sci. , vol.55 , pp. 3508-3513
    • El-Salhy, M.1    Vaali, K.2    Dizdar, V.3    Hausken, T.4
  • 42
    • 57349177561 scopus 로고    scopus 로고
    • Pharmacological demarcation of the growth hormone, gut motility and feeding effects of ghrelin using a novel ghrelin receptor agonist
    • Fraser G.L., Hoveyda H.R., Tannenbaum G.S. Pharmacological demarcation of the growth hormone, gut motility and feeding effects of ghrelin using a novel ghrelin receptor agonist. Endocrinology 2008, 149:6280-6288.
    • (2008) Endocrinology , vol.149 , pp. 6280-6288
    • Fraser, G.L.1    Hoveyda, H.R.2    Tannenbaum, G.S.3
  • 43
    • 0037592273 scopus 로고    scopus 로고
    • Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats
    • Fujino K., Inui A., Asakawa A., Kihara N., Fujimura M., Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J. Physiol. 2003, 550:227-240.
    • (2003) J. Physiol. , vol.550 , pp. 227-240
    • Fujino, K.1    Inui, A.2    Asakawa, A.3    Kihara, N.4    Fujimura, M.5    Fujimiya, M.6
  • 48
    • 33645069631 scopus 로고    scopus 로고
    • Therapeutic action of ghrelin in a mouse model of colitis
    • Gonzalez-Rey E., Chorny A., Delgado M. Therapeutic action of ghrelin in a mouse model of colitis. Gastroenterology 2006, 130:1707-1720.
    • (2006) Gastroenterology , vol.130 , pp. 1707-1720
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 50
    • 33846926049 scopus 로고    scopus 로고
    • Lack of obestatin effects on food intake: should obestatin be renamed ghrelin-associated peptide (GAP)?
    • Gourcerol G., St-Pierre D.H., Tache Y. Lack of obestatin effects on food intake: should obestatin be renamed ghrelin-associated peptide (GAP)?. Regul. Pept. 2007, 141:1-7.
    • (2007) Regul. Pept. , vol.141 , pp. 1-7
    • Gourcerol, G.1    St-Pierre, D.H.2    Tache, Y.3
  • 52
    • 49749084909 scopus 로고    scopus 로고
    • Distribution of obestatin and ghrelin in human tissues: immunoreactive cells in the gastrointestinal tract, pancreas, and mammary glands
    • Gronberg M., Tsolakis A.V., Magnusson L., Janson E.T., Saras J. Distribution of obestatin and ghrelin in human tissues: immunoreactive cells in the gastrointestinal tract, pancreas, and mammary glands. J. Histochem. Cytochem. 2008, 56:793-801.
    • (2008) J. Histochem. Cytochem. , vol.56 , pp. 793-801
    • Gronberg, M.1    Tsolakis, A.V.2    Magnusson, L.3    Janson, E.T.4    Saras, J.5
  • 55
    • 33845992573 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis
    • Han X., Benight N., Osuntokun B., Loesch K., Frank S.J., Denson L.A. Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis. Gut 2007, 56:73-81.
    • (2007) Gut , vol.56 , pp. 73-81
    • Han, X.1    Benight, N.2    Osuntokun, B.3    Loesch, K.4    Frank, S.J.5    Denson, L.A.6
  • 56
    • 67349116804 scopus 로고    scopus 로고
    • Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system
    • Hattori N. Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system. Growth Horm. IGF Res. 2009, 19:187-197.
    • (2009) Growth Horm. IGF Res. , vol.19 , pp. 187-197
    • Hattori, N.1
  • 58
    • 0034802108 scopus 로고    scopus 로고
    • Minireview: ghrelin and the regulation of energy balance - a hypothalamic perspective
    • Horvath T.L., Diano S., Sotonyi P., Heiman M., Tschop M. Minireview: ghrelin and the regulation of energy balance - a hypothalamic perspective. Endocrinology 2001, 142:4163-4169.
    • (2001) Endocrinology , vol.142 , pp. 4163-4169
    • Horvath, T.L.1    Diano, S.2    Sotonyi, P.3    Heiman, M.4    Tschop, M.5
  • 59
    • 0034731310 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue
    • Hosoda H., Kojima M., Matsuo H., Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem. Biophys. Res. Commun. 2000, 279:909-913.
    • (2000) Biochem. Biophys. Res. Commun. , vol.279 , pp. 909-913
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3    Kangawa, K.4
  • 61
    • 33847195401 scopus 로고    scopus 로고
    • Circulating ghrelin in patients with gastric or colorectal cancer
    • Huang Q., Fan Y.Z., Ge B.J., Zhu Q., Tu Z.Y. Circulating ghrelin in patients with gastric or colorectal cancer. Dig. Dis. Sci. 2007, 52:803-809.
    • (2007) Dig. Dis. Sci. , vol.52 , pp. 803-809
    • Huang, Q.1    Fan, Y.Z.2    Ge, B.J.3    Zhu, Q.4    Tu, Z.Y.5
  • 66
    • 77952797035 scopus 로고    scopus 로고
    • The ghrelin-positive cells number is increased in duodenum in children with celiac disease
    • Jarocka-Cyrta E., Kasacka I., Kaczmarski M. The ghrelin-positive cells number is increased in duodenum in children with celiac disease. J. Endocrinol. Invest. 2010, 33:165-170.
    • (2010) J. Endocrinol. Invest. , vol.33 , pp. 165-170
    • Jarocka-Cyrta, E.1    Kasacka, I.2    Kaczmarski, M.3
  • 68
    • 8744303926 scopus 로고    scopus 로고
    • Changes in plasma ghrelin concentration immediately after gastrectomy in patients with early gastric cancer
    • Jeon T.Y., Lee S., Kim H.H., Kim Y.J., Son H.C., Kim D.H., Sim M.S. Changes in plasma ghrelin concentration immediately after gastrectomy in patients with early gastric cancer. J. Clin. Endocrinol. Metab. 2004, 89:5392-5396.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5392-5396
    • Jeon, T.Y.1    Lee, S.2    Kim, H.H.3    Kim, Y.J.4    Son, H.C.5    Kim, D.H.6    Sim, M.S.7
  • 74
    • 77953241787 scopus 로고    scopus 로고
    • Gut hormones: emerging role in immune activation and inflammation
    • Khan W.I., Ghia J.E. Gut hormones: emerging role in immune activation and inflammation. Clin. Exp. Immunol. 2010, 161:19-27.
    • (2010) Clin. Exp. Immunol. , vol.161 , pp. 19-27
    • Khan, W.I.1    Ghia, J.E.2
  • 76
    • 50849133889 scopus 로고    scopus 로고
    • Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection
    • Kodama T., Ashitani J., Matsumoto N., Kangawa K., Nakazato M. Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection. Pulm. Pharmacol. Ther. 2008, 21:774-779.
    • (2008) Pulm. Pharmacol. Ther. , vol.21 , pp. 774-779
    • Kodama, T.1    Ashitani, J.2    Matsumoto, N.3    Kangawa, K.4    Nakazato, M.5
  • 77
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 78
    • 76549113378 scopus 로고    scopus 로고
    • Dietary medium-chain triglycerides prevent chemically induced experimental colitis in rats
    • Kono H., Fujii H., Ishii K., Hosomura N., Ogiku M. Dietary medium-chain triglycerides prevent chemically induced experimental colitis in rats. Transl. Res. 2010, 155:131-141.
    • (2010) Transl. Res. , vol.155 , pp. 131-141
    • Kono, H.1    Fujii, H.2    Ishii, K.3    Hosomura, N.4    Ogiku, M.5
  • 79
    • 77958523704 scopus 로고    scopus 로고
    • Enteral diets enriched with medium-chain triglycerides and N-3 fatty acids prevent chemically induced experimental colitis in rats
    • Kono H., Fujii H., Ogiku M., Tsuchiya M., Ishii K., Hara M. Enteral diets enriched with medium-chain triglycerides and N-3 fatty acids prevent chemically induced experimental colitis in rats. Transl. Res. 2010, 156:282-291.
    • (2010) Transl. Res. , vol.156 , pp. 282-291
    • Kono, H.1    Fujii, H.2    Ogiku, M.3    Tsuchiya, M.4    Ishii, K.5    Hara, M.6
  • 83
    • 73449117883 scopus 로고    scopus 로고
    • Pernicious anemia: new insights from a gastroenterological point of view
    • Lahner E., Annibale B. Pernicious anemia: new insights from a gastroenterological point of view. World J. Gastroenterol. 2009, 15:5121-5128.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 5121-5128
    • Lahner, E.1    Annibale, B.2
  • 86
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
    • Lee H.M., Wang G., Englander E.W., Kojima M., Greeley G.H. Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 2002, 143:185-190.
    • (2002) Endocrinology , vol.143 , pp. 185-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley, G.H.5
  • 91
    • 62749174634 scopus 로고    scopus 로고
    • Partial replacement of dietary (n-6) fatty acids with medium-chain triglycerides decreases the incidence of spontaneous colitis in interleukin-10-deficient mice
    • Mane J., Pedrosa E., Loren V., Ojanguren I., Fluvia L., Cabre E., Rogler G., Gassull M.A. Partial replacement of dietary (n-6) fatty acids with medium-chain triglycerides decreases the incidence of spontaneous colitis in interleukin-10-deficient mice. J. Nutr. 2009, 139:603-610.
    • (2009) J. Nutr. , vol.139 , pp. 603-610
    • Mane, J.1    Pedrosa, E.2    Loren, V.3    Ojanguren, I.4    Fluvia, L.5    Cabre, E.6    Rogler, G.7    Gassull, M.A.8
  • 92
    • 0023686268 scopus 로고
    • The Campylobacter pylori story
    • Marshall B.J. The Campylobacter pylori story. Scand. J. Gastroenterol. 1988, (Suppl. 146):58-66.
    • (1988) Scand. J. Gastroenterol. , Issue.SUPPL. 146 , pp. 58-66
    • Marshall, B.J.1
  • 96
    • 34247101063 scopus 로고    scopus 로고
    • Immunohistochemical and quantitative mRNA assessment of ghrelin expression in gastric and oesophageal adenocarcinoma
    • Mottershead M., Karteris E., Barclay J.Y., Suortamo S., Newbold M., Randeva H., Nwokolo C.U. Immunohistochemical and quantitative mRNA assessment of ghrelin expression in gastric and oesophageal adenocarcinoma. J. Clin. Pathol. 2007, 60:405-409.
    • (2007) J. Clin. Pathol. , vol.60 , pp. 405-409
    • Mottershead, M.1    Karteris, E.2    Barclay, J.Y.3    Suortamo, S.4    Newbold, M.5    Randeva, H.6    Nwokolo, C.U.7
  • 102
    • 0038639060 scopus 로고    scopus 로고
    • Plasma ghrelin following cure of Helicobacter pylori
    • Nwokolo C.U., Freshwater D.A., O'Hare P., Randeva H.S. Plasma ghrelin following cure of Helicobacter pylori. Gut 2003, 52:637-640.
    • (2003) Gut , vol.52 , pp. 637-640
    • Nwokolo, C.U.1    Freshwater, D.A.2    O'Hare, P.3    Randeva, H.S.4
  • 103
    • 77949263115 scopus 로고    scopus 로고
    • Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions
    • Ohman L., Simren M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat. Rev. Gastroenterol. Hepatol. 2010, 7:163-173.
    • (2010) Nat. Rev. Gastroenterol. Hepatol. , vol.7 , pp. 163-173
    • Ohman, L.1    Simren, M.2
  • 104
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • Okayasu I., Hatakeyama S., Yamada M., Ohkusa T., Inagaki Y., Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990, 98:694-702.
    • (1990) Gastroenterology , vol.98 , pp. 694-702
    • Okayasu, I.1    Hatakeyama, S.2    Yamada, M.3    Ohkusa, T.4    Inagaki, Y.5    Nakaya, R.6
  • 107
    • 44949161833 scopus 로고    scopus 로고
    • Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment
    • Parkes G.C., Brostoff J., Whelan K., Sanderson J.D. Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment. Am. J. Gastroenterol. 2008, 103:1557-1567.
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 1557-1567
    • Parkes, G.C.1    Brostoff, J.2    Whelan, K.3    Sanderson, J.D.4
  • 108
    • 0029119213 scopus 로고
    • The incidence of Helicobacter pylori infection
    • Parsonnet J. The incidence of Helicobacter pylori infection. Aliment. Pharmacol. Ther. 1995, 9(Suppl. 2):45-51.
    • (1995) Aliment. Pharmacol. Ther. , vol.9 , Issue.SUPPL. 2 , pp. 45-51
    • Parsonnet, J.1
  • 111
    • 77950367847 scopus 로고    scopus 로고
    • Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats
    • Reimer R.A., Maurer A.D., Lau D.C., Auer R.N. Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats. Physiol. Behav. 2010, 99:605-610.
    • (2010) Physiol. Behav. , vol.99 , pp. 605-610
    • Reimer, R.A.1    Maurer, A.D.2    Lau, D.C.3    Auer, R.N.4
  • 113
    • 0015581604 scopus 로고
    • Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome
    • Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut 1973, 14:125-132.
    • (1973) Gut , vol.14 , pp. 125-132
    • Ritchie, J.1
  • 115
    • 0036678922 scopus 로고    scopus 로고
    • The epidemiology of irritable bowel syndrome in North America: a systematic review
    • Saito Y.A., Schoenfeld P., Locke G.R. The epidemiology of irritable bowel syndrome in North America: a systematic review. Am. J. Gastroenterol. 2002, 97:1910-1915.
    • (2002) Am. J. Gastroenterol. , vol.97 , pp. 1910-1915
    • Saito, Y.A.1    Schoenfeld, P.2    Locke, G.R.3
  • 117
  • 118
    • 38849092560 scopus 로고    scopus 로고
    • Development of drugs for gastrointestinal motor disorders: translating science to clinical need
    • Sanger G.J., Alpers D.H. Development of drugs for gastrointestinal motor disorders: translating science to clinical need. Neurogastroenterol. Motil. 2008, 20:177-184.
    • (2008) Neurogastroenterol. Motil. , vol.20 , pp. 177-184
    • Sanger, G.J.1    Alpers, D.H.2
  • 121
    • 77958582882 scopus 로고    scopus 로고
    • Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants
    • Shin Y.K., Martin B., Kim W., White C.M., Ji S., Sun Y., Smith R.G., Sevigny J., Tschop M.H., Maudsley S., Egan J.M. Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants. PLoS One 2010, 5:e12729.
    • (2010) PLoS One , vol.5
    • Shin, Y.K.1    Martin, B.2    Kim, W.3    White, C.M.4    Ji, S.5    Sun, Y.6    Smith, R.G.7    Sevigny, J.8    Tschop, M.H.9    Maudsley, S.10    Egan, J.M.11
  • 122
    • 0032168626 scopus 로고    scopus 로고
    • Involvement of CD4+ T cells in the development of dextran sulfate sodium-induced experimental colitis and suppressive effect of IgG on their action
    • Shintani N., Nakajima T., Okamoto T., Kondo T., Nakamura N., Mayumi T. Involvement of CD4+ T cells in the development of dextran sulfate sodium-induced experimental colitis and suppressive effect of IgG on their action. Gen. Pharmacol. 1998, 31:477-481.
    • (1998) Gen. Pharmacol. , vol.31 , pp. 477-481
    • Shintani, N.1    Nakajima, T.2    Okamoto, T.3    Kondo, T.4    Nakamura, N.5    Mayumi, T.6
  • 123
    • 25444472609 scopus 로고    scopus 로고
    • Helicobacter pylori infection is associated with reduced circulating ghrelin levels independent of body mass index
    • Shiotani A., Miyanishi T., Uedo N., Iishi H. Helicobacter pylori infection is associated with reduced circulating ghrelin levels independent of body mass index. Helicobacter 2005, 10:373-378.
    • (2005) Helicobacter , vol.10 , pp. 373-378
    • Shiotani, A.1    Miyanishi, T.2    Uedo, N.3    Iishi, H.4
  • 126
    • 13444310997 scopus 로고    scopus 로고
    • High interdigestive and postprandial motilin levels in patients with the irritable bowel syndrome
    • Simren M., Bjornsson E.S., Abrahamsson H. High interdigestive and postprandial motilin levels in patients with the irritable bowel syndrome. Neurogastroenterol. Motil. 2005, 17:51-57.
    • (2005) Neurogastroenterol. Motil. , vol.17 , pp. 51-57
    • Simren, M.1    Bjornsson, E.S.2    Abrahamsson, H.3
  • 127
    • 77952103939 scopus 로고    scopus 로고
    • Covariation of plasma ghrelin and motilin in irritable bowel syndrome
    • Sjolund K., Ekman R., Wierup N. Covariation of plasma ghrelin and motilin in irritable bowel syndrome. Peptides 2010, 31:1109-1112.
    • (2010) Peptides , vol.31 , pp. 1109-1112
    • Sjolund, K.1    Ekman, R.2    Wierup, N.3
  • 131
    • 75049085779 scopus 로고    scopus 로고
    • Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa
    • Stengel A., Goebel M., Wang L., Tache Y., Sachs G., Lambrecht N.W. Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa. Biochem. Biophys. Res. Commun. 2010, 392:67-71.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 67-71
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Tache, Y.4    Sachs, G.5    Lambrecht, N.W.6
  • 132
    • 3343023726 scopus 로고    scopus 로고
    • Plasma ghrelin concentration correlates with the levels of serum pepsinogen I and pepsinogen I/II ratio: a possible novel and non-invasive marker for gastric atrophy
    • Suzuki H., Masaoka T., Hosoda H., Nomura S., Ohara T., Kangawa K., Ishii H., Hibi T. Plasma ghrelin concentration correlates with the levels of serum pepsinogen I and pepsinogen I/II ratio: a possible novel and non-invasive marker for gastric atrophy. Hepatogastroenterology 2004, 51:1249-1254.
    • (2004) Hepatogastroenterology , vol.51 , pp. 1249-1254
    • Suzuki, H.1    Masaoka, T.2    Hosoda, H.3    Nomura, S.4    Ohara, T.5    Kangawa, K.6    Ishii, H.7    Hibi, T.8
  • 136
    • 19444379510 scopus 로고    scopus 로고
    • Distribution of ghrelin-immunoreactive cells in human gastric mucosa: comparison with that of parietal cells
    • Tanaka-Shintani M., Watanabe M. Distribution of ghrelin-immunoreactive cells in human gastric mucosa: comparison with that of parietal cells. J. Gastroenterol. 2005, 40:345-349.
    • (2005) J. Gastroenterol. , vol.40 , pp. 345-349
    • Tanaka-Shintani, M.1    Watanabe, M.2
  • 138
    • 0017610669 scopus 로고
    • Basal and stimulated serum growth hormone concentrations in inflammatory bowel disease
    • Tenore A., Berman W.F., Parks J.S., Bongiovanni A.M. Basal and stimulated serum growth hormone concentrations in inflammatory bowel disease. J. Clin. Endocrinol. Metab. 1977, 44:622-628.
    • (1977) J. Clin. Endocrinol. Metab. , vol.44 , pp. 622-628
    • Tenore, A.1    Berman, W.F.2    Parks, J.S.3    Bongiovanni, A.M.4
  • 139
    • 0034124615 scopus 로고    scopus 로고
    • Irritable bowel syndrome in general practice: prevalence, characteristics, and referral
    • Thompson W.G., Heaton K.W., Smyth G.T., Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics, and referral. Gut 2000, 46:78-82.
    • (2000) Gut , vol.46 , pp. 78-82
    • Thompson, W.G.1    Heaton, K.W.2    Smyth, G.T.3    Smyth, C.4
  • 142
    • 0036777687 scopus 로고    scopus 로고
    • Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats
    • Tschop M., Flora D.B., Mayer J.P., Heiman M.L. Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats. Obes. Res. 2002, 10:991-999.
    • (2002) Obes. Res. , vol.10 , pp. 991-999
    • Tschop, M.1    Flora, D.B.2    Mayer, J.P.3    Heiman, M.L.4
  • 146
    • 32644460639 scopus 로고    scopus 로고
    • Proximal and distal gut hormone secretion in irritable bowel syndrome
    • Van Der Veek P.P., Biemond I., Masclee A.A. Proximal and distal gut hormone secretion in irritable bowel syndrome. Scand. J. Gastroenterol. 2006, 41:170-177.
    • (2006) Scand. J. Gastroenterol. , vol.41 , pp. 170-177
    • Van Der Veek, P.P.1    Biemond, I.2    Masclee, A.A.3
  • 148
    • 47649092734 scopus 로고    scopus 로고
    • Role of ghrelin axis in colorectal cancer: a novel association
    • Waseem T., Javaid Ur R., Ahmad F., Azam M., Qureshi M.A. Role of ghrelin axis in colorectal cancer: a novel association. Peptides 2008, 29:1369-1376.
    • (2008) Peptides , vol.29 , pp. 1369-1376
    • Waseem, T.1    Javaid Ur, R.2    Ahmad, F.3    Azam, M.4    Qureshi, M.A.5
  • 150
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier R.J., Podolsky D.K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007, 448:427-434.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 151
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
    • Yang J., Brown M.S., Liang G., Grishin N.V., Goldstein J.L. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 2008, 132:387-396.
    • (2008) Cell , vol.132 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 152
    • 28544441759 scopus 로고    scopus 로고
    • Ghrelin and a novel preproghrelin isoform are highly expressed in prostate cancer and ghrelin activates mitogen-activated protein kinase in prostate cancer
    • Yeh A.H., Jeffery P.L., Duncan R.P., Herington A.C., Chopin L.K. Ghrelin and a novel preproghrelin isoform are highly expressed in prostate cancer and ghrelin activates mitogen-activated protein kinase in prostate cancer. Clin. Cancer Res. 2005, 11:8295-8303.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8295-8303
    • Yeh, A.H.1    Jeffery, P.L.2    Duncan, R.P.3    Herington, A.C.4    Chopin, L.K.5
  • 153
    • 65449128145 scopus 로고    scopus 로고
    • Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity
    • Youm Y.H., Yang H., Sun Y., Smith R.G., Manley N.R., Vandanmagsar B., Dixit V.D. Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J. Biol. Chem. 2009, 284:7068-7077.
    • (2009) J. Biol. Chem. , vol.284 , pp. 7068-7077
    • Youm, Y.H.1    Yang, H.2    Sun, Y.3    Smith, R.G.4    Manley, N.R.5    Vandanmagsar, B.6    Dixit, V.D.7
  • 154
    • 27744600963 scopus 로고    scopus 로고
    • Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
    • Zhang J.V., Ren P.G., Avsian-Kretchmer O., Luo C.W., Rauch R., Klein C., Hsueh A.J. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 2005, 310:996-999.
    • (2005) Science , vol.310 , pp. 996-999
    • Zhang, J.V.1    Ren, P.G.2    Avsian-Kretchmer, O.3    Luo, C.W.4    Rauch, R.5    Klein, C.6    Hsueh, A.J.7
  • 155
    • 50449085374 scopus 로고    scopus 로고
    • Effect of des-acyl ghrelin on adiposity and glucose metabolism
    • Zhang W., Chai B., Li J.Y., Wang H., Mulholland M.W. Effect of des-acyl ghrelin on adiposity and glucose metabolism. Endocrinology 2008, 149:4710-4716.
    • (2008) Endocrinology , vol.149 , pp. 4710-4716
    • Zhang, W.1    Chai, B.2    Li, J.Y.3    Wang, H.4    Mulholland, M.W.5


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