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Volumn 21, Issue 1, 2009, Pages 59-70

Endogenous and exogenous ghrelin enhance the colonic and gastric manifestations of dextran sodium sulphate-induced colitis in mice

Author keywords

Colitis; Dextran sodium sulphate; Gastric emptying; Ghrelin knockout mice

Indexed keywords

CARBON 14; DEXTRAN SULFATE; GHRELIN; INTERLEUKIN 1BETA; OCTANOIC ACID;

EID: 58149263331     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2008.01184.x     Document Type: Article
Times cited : (54)

References (44)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999 402 : 656 60.
    • (1999) Nature , vol.402 , pp. 656-60
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 2
    • 0035843183 scopus 로고    scopus 로고
    • A role for ghrelin in the central regulation of feeding
    • Nakazato M, Murakami N, Date Y et al. A role for ghrelin in the central regulation of feeding. Nature 2001 409 : 194 8.
    • (2001) Nature , vol.409 , pp. 194-8
    • Nakazato, M.1    Murakami, N.2    Date, Y.3
  • 3
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000 407 : 908 13.
    • (2000) Nature , vol.407 , pp. 908-13
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 4
    • 0037592273 scopus 로고    scopus 로고
    • Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats
    • Fujino K, Inui A, Asakawa A, Kihara N, Fujimura M, Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol 2003 550 : 227 40.
    • (2003) J Physiol , vol.550 , pp. 227-40
    • Fujino, K.1    Inui, A.2    Asakawa, A.3    Kihara, N.4    Fujimura, M.5    Fujimiya, M.6
  • 5
    • 33144482883 scopus 로고    scopus 로고
    • Influence of ghrelin on interdigestive gastrointestinal motility in humans
    • Tack J, Depoortere I, Bisschops R et al. Influence of ghrelin on interdigestive gastrointestinal motility in humans. Gut 2006 55 : 327 33.
    • (2006) Gut , vol.55 , pp. 327-33
    • Tack, J.1    Depoortere, I.2    Bisschops, R.3
  • 6
    • 22644444107 scopus 로고    scopus 로고
    • Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro
    • Kitazawa T, De Smet B, Verbeke K, Depoortere I, Peeters TL. Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro. Gut 2005 54 : 1078 84.
    • (2005) Gut , vol.54 , pp. 1078-84
    • Kitazawa, T.1    De Smet, B.2    Verbeke, K.3    Depoortere, I.4    Peeters, T.L.5
  • 8
    • 0036083505 scopus 로고    scopus 로고
    • Ghrelin/motilin-related peptide is a potent prokinetic to reverse gastric postoperative ileus in rat
    • Trudel L, Tomasetto C, Rio MC et al. Ghrelin/motilin-related peptide is a potent prokinetic to reverse gastric postoperative ileus in rat. Am J Physiol Gastrointest Liver Physiol 2002 282 : G948 52.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282
    • Trudel, L.1    Tomasetto, C.2    Rio, M.C.3
  • 9
    • 4344584000 scopus 로고    scopus 로고
    • Effect of ghrelin and growth hormone-releasing peptide 6 on septic ileus in mice
    • De Winter BY, De Man JG, Seerden TC et al. Effect of ghrelin and growth hormone-releasing peptide 6 on septic ileus in mice. Neurogastroenterol Motil 2004 16 : 439 46.
    • (2004) Neurogastroenterol Motil , vol.16 , pp. 439-46
    • De Winter, B.Y.1    De Man, J.G.2    Seerden, T.C.3
  • 10
    • 0034841199 scopus 로고    scopus 로고
    • GH, GH receptor, GH secretagogue receptor, and ghrelin expression in human T cells, B cells, and neutrophils
    • Hattori N, Saito T, Yagyu T, Jiang BH, Kitagawa K, Inagaki C. GH, GH receptor, GH secretagogue receptor, and ghrelin expression in human T cells, B cells, and neutrophils. J Clin Endocrinol Metab 2001 86 : 4284 91.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4284-91
    • Hattori, N.1    Saito, T.2    Yagyu, T.3    Jiang, B.H.4    Kitagawa, K.5    Inagaki, C.6
  • 11
    • 3242749843 scopus 로고    scopus 로고
    • Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells
    • Dixit VD, Schaffer EM, Pyle RS et al. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest 2004 114 : 57 66.
    • (2004) J Clin Invest , vol.114 , pp. 57-66
    • Dixit, V.D.1    Schaffer, E.M.2    Pyle, R.S.3
  • 12
    • 33645684644 scopus 로고    scopus 로고
    • Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells
    • Zhao D, Zhan Y, Zeng H, Moyer MP, Mantzoros CS, Pothoulakis C. Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells. J Cell Biochem 2006 97 : 1317 27.
    • (2006) J Cell Biochem , vol.97 , pp. 1317-27
    • Zhao, D.1    Zhan, Y.2    Zeng, H.3    Moyer, M.P.4    Mantzoros, C.S.5    Pothoulakis, C.6
  • 14
    • 39149099430 scopus 로고    scopus 로고
    • Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways
    • Waseem T, Duxbury M, Ito H, Ashley SW, Robinson MK. Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery 2008 143 : 334 42.
    • (2008) Surgery , vol.143 , pp. 334-42
    • Waseem, T.1    Duxbury, M.2    Ito, H.3    Ashley, S.W.4    Robinson, M.K.5
  • 16
    • 0037225643 scopus 로고    scopus 로고
    • Ghrelin protects against ethanol-induced gastric ulcers in rats: studies on the mechanisms of action
    • Sibilia V, Rindi G, Pagani F et al. Ghrelin protects against ethanol-induced gastric ulcers in rats: studies on the mechanisms of action. Endocrinology 2003 144 : 353 9.
    • (2003) Endocrinology , vol.144 , pp. 353-9
    • Sibilia, V.1    Rindi, G.2    Pagani, F.3
  • 17
    • 1842423853 scopus 로고    scopus 로고
    • Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage
    • Brzozowski T, Konturek PC, Konturek SJ et al. Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage. Regul Pept 2004 120 : 39 51.
    • (2004) Regul Pept , vol.120 , pp. 39-51
    • Brzozowski, T.1    Konturek, P.C.2    Konturek, S.J.3
  • 18
    • 33645837808 scopus 로고    scopus 로고
    • Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide
    • Konturek PC, Brzozowski T, Walter B et al. Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide. Eur J Pharmacol 2006 536 : 171 81.
    • (2006) Eur J Pharmacol , vol.536 , pp. 171-81
    • Konturek, P.C.1    Brzozowski, T.2    Walter, B.3
  • 19
    • 33645069631 scopus 로고    scopus 로고
    • Therapeutic action of ghrelin in a mouse model of colitis
    • Gonzalez-Rey E, Chorny A, Delgado M. Therapeutic action of ghrelin in a mouse model of colitis. Gastroenterology 2006 130 : 1707 20.
    • (2006) Gastroenterology , vol.130 , pp. 1707-20
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 20
    • 33144474423 scopus 로고    scopus 로고
    • Circulating ghrelin levels in patients with inflammatory bowel disease
    • Peracchi M, Bardella MT, Caprioli F et al. Circulating ghrelin levels in patients with inflammatory bowel disease. Gut 2006 55 : 432 3.
    • (2006) Gut , vol.55 , pp. 432-3
    • Peracchi, M.1    Bardella, M.T.2    Caprioli, F.3
  • 22
    • 54349104242 scopus 로고    scopus 로고
    • Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohn's disease
    • Hosomi S, Oshitani N, Kamata N et al. Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohn's disease. Inflamm Bowel 2008 14 : 1205 13.
    • (2008) Inflamm Bowel , vol.14 , pp. 1205-13
    • Hosomi, S.1    Oshitani, N.2    Kamata, N.3
  • 23
    • 27444446161 scopus 로고    scopus 로고
    • Ghrelin: a new player in the control of gastrointestinal functions
    • Peeters TL. Ghrelin: a new player in the control of gastrointestinal functions. Gut 2005 54 : 1638 49.
    • (2005) Gut , vol.54 , pp. 1638-49
    • Peeters, T.L.1
  • 24
    • 0018876511 scopus 로고
    • Abnormal gastrocolonic response in patients with ulcerative colitis
    • Snape WJ Jr., Matarazzo SA, Cohen S. Abnormal gastrocolonic response in patients with ulcerative colitis. Gut 1980 21 : 392 6.
    • (1980) Gut , vol.21 , pp. 392-6
    • Snape Jr., W.J.1    Matarazzo, S.A.2    Cohen, S.3
  • 25
    • 0026261530 scopus 로고
    • Colonic motility and transit in health and ulcerative colitis
    • Reddy SN, Bazzocchi G, Chan S et al. Colonic motility and transit in health and ulcerative colitis. Gastroenterology 1991 101 : 1289 97.
    • (1991) Gastroenterology , vol.101 , pp. 1289-97
    • Reddy, S.N.1    Bazzocchi, G.2    Chan, S.3
  • 26
    • 0032792001 scopus 로고    scopus 로고
    • Differential changes in ACh-, motilin-, substance P-, and K(+)-induced contractility in rabbit colitis
    • Depoortere I, Van Assche G, Thijs T, Geboes K, Peeters TL. Differential changes in ACh-, motilin-, substance P-, and K(+)-induced contractility in rabbit colitis. Am J Physiol 1999 277 : G61 8.
    • (1999) Am J Physiol , vol.277
    • Depoortere, I.1    Van Assche, G.2    Thijs, T.3    Geboes, K.4    Peeters, T.L.5
  • 27
    • 0023846046 scopus 로고
    • Increased responsiveness of jejunal longitudinal muscle in Trichinella-infected rats
    • Vermillion DL, Collins SM. Increased responsiveness of jejunal longitudinal muscle in Trichinella-infected rats. Am J Physiol 1988 254 : G124 9.
    • (1988) Am J Physiol , vol.254
    • Vermillion, D.L.1    Collins, S.M.2
  • 28
    • 0034103422 scopus 로고    scopus 로고
    • Impaired nitrergic innervation in rat colitis induced by dextran sulfate sodium
    • Mizuta Y, Isomoto H, Takahashi T. Impaired nitrergic innervation in rat colitis induced by dextran sulfate sodium. Gastroenterology 2000 118 : 714 23.
    • (2000) Gastroenterology , vol.118 , pp. 714-23
    • Mizuta, Y.1    Isomoto, H.2    Takahashi, T.3
  • 29
    • 0036254897 scopus 로고    scopus 로고
    • Generalized loss of inhibitory innervation reverses serotonergic inhibition into excitation in a rabbit model of TNBS-colitis
    • Depoortere I, Thijs T, Peeters TL. Generalized loss of inhibitory innervation reverses serotonergic inhibition into excitation in a rabbit model of TNBS-colitis. Br J Pharmacol 2002 135 : 2011 9.
    • (2002) Br J Pharmacol , vol.135 , pp. 2011-9
    • Depoortere, I.1    Thijs, T.2    Peeters, T.L.3
  • 30
    • 0028806571 scopus 로고
    • Gastric emptying of solids in patients with nonobstructive Crohn's disease is sometimes delayed
    • Annese V, Bassotti G, Napolitano G et al. Gastric emptying of solids in patients with nonobstructive Crohn's disease is sometimes delayed. J Clin Gastroenterol 1995 21 : 279 82.
    • (1995) J Clin Gastroenterol , vol.21 , pp. 279-82
    • Annese, V.1    Bassotti, G.2    Napolitano, G.3
  • 33
    • 33846959506 scopus 로고    scopus 로고
    • Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve
    • De Schepper HU, De Man JG, Van Nassauw L et al. Acute distal colitis impairs gastric emptying in rats via an extrinsic neuronal reflex pathway involving the pelvic nerve. Gut 2007 56 : 195 202.
    • (2007) Gut , vol.56 , pp. 195-202
    • De Schepper, H.U.1    De Man, J.G.2    Van Nassauw, L.3
  • 34
    • 29244469386 scopus 로고    scopus 로고
    • Energy homeostasis and gastric emptying in ghrelin knockout mice
    • De Smet B, Depoortere I, Moechars D et al. Energy homeostasis and gastric emptying in ghrelin knockout mice. J Pharmacol Exp Ther 2006 316 : 431 9.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 431-9
    • De Smet, B.1    Depoortere, I.2    Moechars, D.3
  • 35
    • 0031736096 scopus 로고    scopus 로고
    • Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines
    • Dieleman LA, Palmen MJ, Akol H et al. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 1998 114 : 385 91.
    • (1998) Clin Exp Immunol , vol.114 , pp. 385-91
    • Dieleman, L.A.1    Palmen, M.J.2    Akol, H.3
  • 36
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker
    • Bradley PP, Priebat DA, Christensen RD, Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 1982 78 : 206 9.
    • (1982) J Invest Dermatol , vol.78 , pp. 206-9
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3    Rothstein, G.4
  • 37
    • 0242438600 scopus 로고    scopus 로고
    • Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats
    • Thompson NM, Davies JS, Mode A, Houston PA, Wells T. Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats. Endocrinology 2003 144 : 4859 67.
    • (2003) Endocrinology , vol.144 , pp. 4859-67
    • Thompson, N.M.1    Davies, J.S.2    Mode, A.3    Houston, P.A.4    Wells, T.5
  • 38
    • 22344453974 scopus 로고    scopus 로고
    • Growth hormone inhibits signal transducer and activator of transcription 3 activation and reduces disease activity in murine colitis
    • Han X, Sosnowska D, Bonkowski EL, Denson LA. Growth hormone inhibits signal transducer and activator of transcription 3 activation and reduces disease activity in murine colitis. Gastroenterology 2005 129 : 185 203.
    • (2005) Gastroenterology , vol.129 , pp. 185-203
    • Han, X.1    Sosnowska, D.2    Bonkowski, E.L.3    Denson, L.A.4
  • 40
    • 0141957932 scopus 로고    scopus 로고
    • Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin
    • Dass NB, Munonyara M, Bassil AK et al. Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin. Neuroscience 2003 120 : 443 53.
    • (2003) Neuroscience , vol.120 , pp. 443-53
    • Dass, N.B.1    Munonyara, M.2    Bassil, A.K.3
  • 41
    • 0027330843 scopus 로고
    • Interleukin 1 beta-induced increase in substance P in rat myenteric plexus
    • Hurst SM, Stanisz AM, Sharkey KA, Collins SM. Interleukin 1 beta-induced increase in substance P in rat myenteric plexus. Gastroenterology 1993 105 : 1754 60.
    • (1993) Gastroenterology , vol.105 , pp. 1754-60
    • Hurst, S.M.1    Stanisz, A.M.2    Sharkey, K.A.3    Collins, S.M.4
  • 42
    • 0028943362 scopus 로고
    • C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signaling. Role of receptor phosphorylation in signal attenuation
    • Alblas J, van Etten I, Khanum A, Moolenaar WH. C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signaling. Role of receptor phosphorylation in signal attenuation. J Biol Chem 1995 270 : 8944 51.
    • (1995) J Biol Chem , vol.270 , pp. 8944-51
    • Alblas, J.1    Van Etten, I.2    Khanum, A.3    Moolenaar, W.H.4
  • 43
    • 33744485247 scopus 로고    scopus 로고
    • Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway
    • Mousseaux D, Le Gallic L, Ryan J et al. Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway. Br J Pharmacol 2006 148 : 350 65.
    • (2006) Br J Pharmacol , vol.148 , pp. 350-65
    • Mousseaux, D.1    Le Gallic, L.2    Ryan, J.3
  • 44
    • 0344013162 scopus 로고    scopus 로고
    • Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro
    • Orkin RD, New DI, Norman D et al. Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro. J Endocrinol Invest 2003 26 : 743 7.
    • (2003) J Endocrinol Invest , vol.26 , pp. 743-7
    • Orkin, R.D.1    New, D.I.2    Norman, D.3


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