-
2
-
-
18444379959
-
Infliximab reverses growth hormone resistance associated with inflammatory bowel disease
-
Vespasiani Gentilucci U, Caviglia R, Picardi A, et al. Infliximab reverses growth hormone resistance associated with inflammatory bowel disease. Aliment Pharmacol Ther 2005;21:1063-71.
-
(2005)
Aliment Pharmacol Ther
, vol.21
, pp. 1063-1071
-
-
Vespasiani Gentilucci, U.1
Caviglia, R.2
Picardi, A.3
-
3
-
-
0025912981
-
Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease
-
Murch SH, Lamkin VA, Savage MO, et al. Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. Gut 1991;32:913-17.
-
(1991)
Gut
, vol.32
, pp. 913-917
-
-
Murch, S.H.1
Lamkin, V.A.2
Savage, M.O.3
-
4
-
-
0141613187
-
A prospective study of the efficacy and tolerance of a chimeric antibody to tumor necrosis factors (remicade) in severe pediatric Crohn disease
-
Cezard JP, Nouaili N, Talbotec C, et al. A prospective study of the efficacy and tolerance of a chimeric antibody to tumor necrosis factors (remicade) in severe pediatric Crohn disease. J Pediatr Gastroenterol Nutr 2003;36:632-6.
-
(2003)
J Pediatr Gastroenterol Nutr
, vol.36
, pp. 632-636
-
-
Cezard, J.P.1
Nouaili, N.2
Talbotec, C.3
-
5
-
-
19044370818
-
Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis
-
DiFedele LM, He J, Bonkowski EL, et al. Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis. Gastroenterology 2005;128:1278-91.
-
(2005)
Gastroenterology
, vol.128
, pp. 1278-1291
-
-
DiFedele, L.M.1
He, J.2
Bonkowski, E.L.3
-
6
-
-
1542410502
-
The effect of recombinant human growth hormone (rhGH) on trinitrobenzene sulfonic acid-Induced colitis in rats: An experimental study
-
Kara E, Sungurtekin H, Sungertekin U, et al. The effect of recombinant human growth hormone (rhGH) on trinitrobenzene sulfonic acid-Induced colitis in rats: an experimental study. Inflamm Bowel Dis 2004;10:112-15.
-
(2004)
Inflamm Bowel Dis
, vol.10
, pp. 112-115
-
-
Kara, E.1
Sungurtekin, H.2
Sungertekin, U.3
-
7
-
-
22344453974
-
Growth hormone reduces STAT3 activation and improves disease activity in murine colitis
-
Han X, Sosnowska D, Bonkowski E, et al. Growth hormone reduces STAT3 activation and improves disease activity in murine colitis. Gastroenterology 2005;129:185-203.
-
(2005)
Gastroenterology
, vol.129
, pp. 185-203
-
-
Han, X.1
Sosnowska, D.2
Bonkowski, E.3
-
8
-
-
0034212467
-
A preliminary study of growth hormone therapy for Crohn's disease
-
Slonim AE, Bulone L, Damore MB, et al. A preliminary study of growth hormone therapy for Crohn's disease. N Engl J Med 2000;342:1633-7.
-
(2000)
N Engl J Med
, vol.342
, pp. 1633-1637
-
-
Slonim, A.E.1
Bulone, L.2
Damore, M.B.3
-
9
-
-
0035123651
-
Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone
-
Williams KL, Fuller CR, Dieleman LA, et al. Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone. Gastroenterology 2001;120:925-37.
-
(2001)
Gastroenterology
, vol.120
, pp. 925-937
-
-
Williams, K.L.1
Fuller, C.R.2
Dieleman, L.A.3
-
10
-
-
0025157054
-
Growth hormone receptor expression in the rat gastrointestinal tract
-
Lobie PE, Breipohl W, Waters MJ. Growth hormone receptor expression in the rat gastrointestinal tract. Endocrinology 1990;126:299-306.
-
(1990)
Endocrinology
, vol.126
, pp. 299-306
-
-
Lobie, P.E.1
Breipohl, W.2
Waters, M.J.3
-
11
-
-
0034878836
-
STAT5b is required for GH-induced liver IGF-1 gene expression
-
Davey HW, Xie T, McLachlan MJ, et al. STAT5b is required for GH-induced liver IGF-1 gene expression. Endocrinology 2001;142:3836-41.
-
(2001)
Endocrinology
, vol.142
, pp. 3836-3841
-
-
Davey, H.W.1
Xie, T.2
McLachlan, M.J.3
-
12
-
-
0037329337
-
A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French population
-
Meirhaeghe A, Fajas L, Gouilleux F, et al. A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French population. Arterioscler Thromb Vasc Biol 2003;23:289-94.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 289-294
-
-
Meirhaeghe, A.1
Fajas, L.2
Gouilleux, F.3
-
13
-
-
0035668404
-
An open-label trial of the PPAR-gamma ligand rosiglitazone for active ulcerative colitis
-
Lewis JD, Lichtenstein GR, Stein RB, et al. An open-label trial of the PPAR-gamma ligand rosiglitazone for active ulcerative colitis. Am J Gastroenterol 2001;96:3323-8.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 3323-3328
-
-
Lewis, J.D.1
Lichtenstein, G.R.2
Stein, R.B.3
-
14
-
-
0038185266
-
A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model
-
Katayama K, Wada K, Nakajima A, et al. A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model. Gastroenterology 2003;124:1315-24.
-
(2003)
Gastroenterology
, vol.124
, pp. 1315-1324
-
-
Katayama, K.1
Wada, K.2
Nakajima, A.3
-
15
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
-
Su CG, Wen X, Bailey ST, et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J Clin Invest 1999;104:383-9.
-
(1999)
J Clin Invest
, vol.104
, pp. 383-389
-
-
Su, C.G.1
Wen, X.2
Bailey, S.T.3
-
16
-
-
0035794293
-
Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies
-
Desreumaux P, Dubuquoy L, Nutten S, et al. Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies. J Exp Med 2001;193:827-38.
-
(2001)
J Exp Med
, vol.193
, pp. 827-838
-
-
Desreumaux, P.1
Dubuquoy, L.2
Nutten, S.3
-
17
-
-
20944445862
-
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma
-
Rousseaux C, Lefebvre B, Dubuquoy L, et al. Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. J Exp Med 2005;201:1205-15.
-
(2005)
J Exp Med
, vol.201
, pp. 1205-1215
-
-
Rousseaux, C.1
Lefebvre, B.2
Dubuquoy, L.3
-
18
-
-
15944363392
-
Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms
-
Schaefer KL, Denevich S, Ma C, et al. Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms. Inflamm Bowel Dis 2005;11:244-52.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 244-252
-
-
Schaefer, K.L.1
Denevich, S.2
Ma, C.3
-
19
-
-
0242580058
-
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice
-
Snow JW, Abraham N, Ma MC, et al. Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice. J Immunol 2003;171:5042-50.
-
(2003)
J Immunol
, vol.171
, pp. 5042-5050
-
-
Snow, J.W.1
Abraham, N.2
Ma, M.C.3
-
20
-
-
0032913394
-
Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial
-
D'Haens G, Van Deventer S, Van Hogezand R, et al. Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: a European multicenter trial. Gastroenterology 1999;116:1029-34.
-
(1999)
Gastroenterology
, vol.116
, pp. 1029-1034
-
-
D'Haens, G.1
Van Deventer, S.2
Van Hogezand, R.3
-
21
-
-
0036151047
-
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
-
ten Hove T, van Montfrans C, Peppelenbosch MP, et al. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002;50:206-11.
-
(2002)
Gut
, vol.50
, pp. 206-211
-
-
ten Hove, T.1
van Montfrans, C.2
Peppelenbosch, M.P.3
-
22
-
-
0038153911
-
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis
-
Marini M, Bamias G, Rivera-Nieves J, et al. TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proc Natl Acad Sci USA 2003;100:8366-71.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8366-8371
-
-
Marini, M.1
Bamias, G.2
Rivera-Nieves, J.3
-
23
-
-
0032923705
-
Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis
-
Baert FJ, D'Haens GR, Peeters M, et al. Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis. Gastroenterology 1999;116:22-8.
-
(1999)
Gastroenterology
, vol.116
, pp. 22-28
-
-
Baert, F.J.1
D'Haens, G.R.2
Peeters, M.3
-
24
-
-
0346461662
-
Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease
-
Di Sabatino A, Ciccocioppo R, Cinque B, et al. Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease. Gut 2004;53:70-7.
-
(2004)
Gut
, vol.53
, pp. 70-77
-
-
Di Sabatino, A.1
Ciccocioppo, R.2
Cinque, B.3
-
25
-
-
0033565302
-
Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance
-
Ina K, Itoh J, Fukushima K, et al. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. J Immunol 1999;163:1081-90.
-
(1999)
J Immunol
, vol.163
, pp. 1081-1090
-
-
Ina, K.1
Itoh, J.2
Fukushima, K.3
-
26
-
-
0035816531
-
Growth hormone (GH)-induced dimerization inhibits phorbol ester-stimulated GH receptor proteolysis
-
Zhang Y, Guan R, Jiang J, et al. Growth hormone (GH)-induced dimerization inhibits phorbol ester-stimulated GH receptor proteolysis. J Biol Chem 2001;276:24565-73.
-
(2001)
J Biol Chem
, vol.276
, pp. 24565-24573
-
-
Zhang, Y.1
Guan, R.2
Jiang, J.3
-
27
-
-
21444457762
-
Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage
-
Cowan JW, Wang X, Guan R, et al. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. J Biol Chem 2005;280:19331-42.
-
(2005)
J Biol Chem
, vol.280
, pp. 19331-19342
-
-
Cowan, J.W.1
Wang, X.2
Guan, R.3
-
28
-
-
0034327839
-
Heritable susceptibility for colitis in mice induced by IL-10 deficiency
-
Bristol IJ, Farmer MA, Cong Y, et al. Heritable susceptibility for colitis in mice induced by IL-10 deficiency. Inflamm Bowel Dis 2000;6:290-302.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 290-302
-
-
Bristol, I.J.1
Farmer, M.A.2
Cong, Y.3
-
29
-
-
0041324821
-
Reduced expression of the growth hormone and type 1 insulin-like growth factor receptors in human somatotroph tumours and an analysis of possible mutations of the growth hormone receptor
-
Kola B, Korbonits M, Diaz-Cano S, et al. Reduced expression of the growth hormone and type 1 insulin-like growth factor receptors in human somatotroph tumours and an analysis of possible mutations of the growth hormone receptor. Clin Endocrinol (Oxf), 2003;59:328-38.
-
(2003)
Clin Endocrinol (Oxf)
, vol.59
, pp. 328-338
-
-
Kola, B.1
Korbonits, M.2
Diaz-Cano, S.3
-
30
-
-
0242330303
-
Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: A statewide population-based study
-
Kugathasan S, Judd RH, Hoffmann RG, et al. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J Pediatr 2003;143:525-31.
-
(2003)
J Pediatr
, vol.143
, pp. 525-531
-
-
Kugathasan, S.1
Judd, R.H.2
Hoffmann, R.G.3
-
31
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003;3:521-33.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
32
-
-
4544305960
-
Infliximab heals intestinal inflammatory lesions and restores growth in children with Crohn's disease
-
Borrelli O, Bascietto C, Viola F, et al. Infliximab heals intestinal inflammatory lesions and restores growth in children with Crohn's disease. Dig Liver Dis 2004;36:342-7.
-
(2004)
Dig Liver Dis
, vol.36
, pp. 342-347
-
-
Borrelli, O.1
Bascietto, C.2
Viola, F.3
-
33
-
-
0034994026
-
TNF-alpha downregulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding
-
Denson LA, Menon RK, Shaufl A, et al. TNF-alpha downregulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding. J Clin Invest 2001;107:1451-8.
-
(2001)
J Clin Invest
, vol.107
, pp. 1451-1458
-
-
Denson, L.A.1
Menon, R.K.2
Shaufl, A.3
-
34
-
-
19944417551
-
In vivo analysis of growth hormone receptor signaling domains and their associated transcripts
-
Rowland JE, Lichanska AM, Kerr LM, et al. In vivo analysis of growth hormone receptor signaling domains and their associated transcripts. Mol Cell Biol 2005;25:66-77.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 66-77
-
-
Rowland, J.E.1
Lichanska, A.M.2
Kerr, L.M.3
-
35
-
-
0034021675
-
Growth failure occurs through a decrease in insulin-like growth factor 1 which is independent of undernutrition in a rat model of colitis
-
Ballinger AB, Azooz O, El-Haj T, et al. Growth failure occurs through a decrease in insulin-like growth factor 1 which is independent of undernutrition in a rat model of colitis. Gut 2000;46:694-700.
-
(2000)
Gut
, vol.46
, pp. 694-700
-
-
Ballinger, A.B.1
Azooz, O.2
El-Haj, T.3
-
36
-
-
0036521607
-
Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation
-
Lehtonen A, Matikainen S, Miettinen M, et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation. J Leukoc Biol 2002;71:511-19.
-
(2002)
J Leukoc Biol
, vol.71
, pp. 511-519
-
-
Lehtonen, A.1
Matikainen, S.2
Miettinen, M.3
-
37
-
-
22344444197
-
Growth hormone reduces the severity of fibrosis associated with chronic intestinal inflammation
-
Theiss AL, Fuller CR, Simmons JG, et al. Growth hormone reduces the severity of fibrosis associated with chronic intestinal inflammation. Gastroenterology 2005;129:204-19.
-
(2005)
Gastroenterology
, vol.129
, pp. 204-219
-
-
Theiss, A.L.1
Fuller, C.R.2
Simmons, J.G.3
|