Comparison of pharmacological modulation of APP metabolism in primary chicken telencephalic neurons and in a human neuroglioma cell line

Journal of Molecular Neuroscience

Volumn 43, Issue 3, 2011, Pages 257-267

  Czvitkovich, Stefan ^a   Duller, Stephan ^a   Mathiesen, Else ^a   Lorenzoni, Klaus ^a   Imbimbo, Bruno P ^b   Hutter Paier, Birgit ^a   Windisch, Manfred ^a   Wronski, Robert ^a  

^a JSW Life Sciences GmbH   (Austria)

^b CHIESI FARMACEUTICI S P A   (Italy)

Author keywords

A secretion; Alzheimer's disease; Culture model; Drug testing; Secretase

Indexed keywords

3,5 BIS(4 NITROPHENOXY)BENZOIC ACID; 5 FLUORO 2 METHYL 1 [PARA(METHYLTHIO)BENZYLIDENE]INDENE 3 ACETIC ACID; AGENTS AFFECTING PROTEIN METABOLISM; AMYLOID BETA 38 PROTEIN; AMYLOID BETA 40 PROTEIN; AMYLOID BETA 42 PROTEIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 4 INHIBITOR; BETA SECRETASE INHIBITOR; CALPEPTIN; MUTANT PROTEIN; N(N 3,5 DIFLUOROPHENACETYL)LEVO ALANYL S PHENYLGLYCINE METHYL ESTER; SULINDAC SULFIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL IMMORTALIZATION; CHEMOSENSITIVITY; CHICKEN; CONTROLLED STUDY; DRUG EFFICACY; EMBRYO; ENZYME INHIBITION; EXPERIMENTAL MODEL; GENE MUTATION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SYNTHESIS INHIBITION; TELENCEPHALON; TELENCEPHALON NERVE CELL;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPARTIC ACID ENDOPEPTIDASES; CALPAIN; CELL LINE, TUMOR; CELLS, CULTURED; CHICKENS; CULTURE MEDIA, CONDITIONED; GLIOMA; HUMANS; MODELS, ANIMAL; MUTATION; NEURONS; TELENCEPHALON;

EID: 79955845595     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-010-9416-z     Document Type: Article

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