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Volumn 49, Issue 6, 2006, Pages 351-363

Control of MAPK signaling specificity by a conserved residue in the MEK-binding domain of the yeast scaffold protein Ste5

Author keywords

Activated kinase; Scaffold; Specificity; Ste5; Ste7

Indexed keywords

HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MUTANT PROTEIN; PHEROMONE; PROTEIN STE5; SCAFFOLD PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 33646710154     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-006-0061-6     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 3342900058 scopus 로고    scopus 로고
    • Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
    • Andersson J, Simpson DM, Qi M, Wang Y, Elion EA (2004) Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J 23:2564-2576
    • (2004) EMBO J , vol.23 , pp. 2564-2576
    • Andersson, J.1    Simpson, D.M.2    Qi, M.3    Wang, Y.4    Elion, E.A.5
  • 2
    • 11144352246 scopus 로고    scopus 로고
    • Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast
    • Bao MZ, Schwartz MA, Cantin GT, Yates JR 3rd, Madhani HD (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119:991-1000
    • (2004) Cell , vol.119 , pp. 991-1000
    • Bao, M.Z.1    Schwartz, M.A.2    Cantin, G.T.3    Yates III, J.R.4    Madhani, H.D.5
  • 3
    • 11144236161 scopus 로고    scopus 로고
    • A walk-through of the yeast mating pheromone response pathway
    • Bardwell L (2005) A walk-through of the yeast mating pheromone response pathway. Peptides 26:339-350
    • (2005) Peptides , vol.26 , pp. 339-350
    • Bardwell, L.1
  • 4
    • 0029992810 scopus 로고    scopus 로고
    • Signaling in the yeast pheromone response pathway: Specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7
    • Bardwell L, Cook JG, Chang EC, Cairns BR, Thorner J (1996) Signaling in the yeast pheromone response pathway: Specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol Cell Biol 16:3637-3650
    • (1996) Mol Cell Biol , vol.16 , pp. 3637-3650
    • Bardwell, L.1    Cook, J.G.2    Chang, E.C.3    Cairns, B.R.4    Thorner, J.5
  • 5
    • 0035928744 scopus 로고    scopus 로고
    • MAPK specificity in the yeast pheromone response independent of transcriptional activation
    • Breitkreutz A, Boucher L, Tyers M (2001) MAPK specificity in the yeast pheromone response independent of transcriptional activation. Curr Biol 11:1266-1271
    • (2001) Curr Biol , vol.11 , pp. 1266-1271
    • Breitkreutz, A.1    Boucher, L.2    Tyers, M.3
  • 6
    • 11244342204 scopus 로고    scopus 로고
    • Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development
    • Bruckner S, Kohler T, Braus GH, Heise B, Bolte M, Mosch HU (2004) Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development. Curr Genet 46:331-342
    • (2004) Curr Genet , vol.46 , pp. 331-342
    • Bruckner, S.1    Kohler, T.2    Braus, G.H.3    Heise, B.4    Bolte, M.5    Mosch, H.U.6
  • 7
    • 0027983908 scopus 로고
    • Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
    • Choi KY, Satterberg B, Lyons DM, Elion EA (1994) Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 78:499-512
    • (1994) Cell , vol.78 , pp. 499-512
    • Choi, K.Y.1    Satterberg, B.2    Lyons, D.M.3    Elion, E.A.4
  • 8
    • 0032896036 scopus 로고    scopus 로고
    • Characterization of Fus3 localization: Active Fus3 localizes in complexes of varying size and specific activity
    • Choi KY, Kranz JE, Mahanty SK, Park KS, Elion EA (1999) Characterization of Fus3 localization: Active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10:1553-1568
    • (1999) Mol Biol Cell , vol.10 , pp. 1553-1568
    • Choi, K.Y.1    Kranz, J.E.2    Mahanty, S.K.3    Park, K.S.4    Elion, E.A.5
  • 9
    • 11144340454 scopus 로고    scopus 로고
    • Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast
    • Chou S, Huang L, Liu H (2004) Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell 119:981-990
    • (2004) Cell , vol.119 , pp. 981-990
    • Chou, S.1    Huang, L.2    Liu, H.3
  • 10
    • 0035203511 scopus 로고    scopus 로고
    • MAP kinase dynamics in response to pheromones in budding yeast
    • van Drogen F, Stucke VM, Jorritsma G, Peter M (2001) MAP kinase dynamics in response to pheromones in budding yeast. Nat Cell Biol 3:1051-1059
    • (2001) Nat Cell Biol , vol.3 , pp. 1051-1059
    • van Drogen, F.1    Stucke, V.M.2    Jorritsma, G.3    Peter, M.4
  • 11
    • 0035195491 scopus 로고    scopus 로고
    • The Ste5p scaffold
    • Elion EA (2001) The Ste5p scaffold. J Cell Sci 114:3967-3978
    • (2001) J Cell Sci , vol.114 , pp. 3967-3978
    • Elion, E.A.1
  • 12
    • 0026408150 scopus 로고
    • Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions
    • Elion EA, Brill JA, Fink GR (1991) Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions. Cold Spring Harb Symp Quant Biol 56:41-49
    • (1991) Cold Spring Harb Symp Quant Biol , vol.56 , pp. 41-49
    • Elion, E.A.1    Brill, J.A.2    Fink, G.R.3
  • 13
    • 0030605380 scopus 로고    scopus 로고
    • Feedback regulation of map kinase signal pathways
    • discussion 148-149
    • Errede B, Ge QY (1996) Feedback regulation of map kinase signal pathways. Philos Trans R Soc Lond B Biol Sci 351:143-148; discussion 148-149
    • (1996) Philos Trans R Soc Lond B Biol Sci , vol.351 , pp. 143-148
    • Errede, B.1    Ge, Q.Y.2
  • 14
    • 14044266923 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiae
    • Flatauer LJ, Zadeh SF, Bardwell L (2005) Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiae. Mol Cell Biol 25:1793-1803
    • (2005) Mol Cell Biol , vol.25 , pp. 1793-1803
    • Flatauer, L.J.1    Zadeh, S.F.2    Bardwell, L.3
  • 15
    • 8744224516 scopus 로고    scopus 로고
    • Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade
    • Flotho A, Simpson DM, Qi M, Elion EA (2004) Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade. J Biol Chem 279:47391-47401
    • (2004) J Biol Chem , vol.279 , pp. 47391-47401
    • Flotho, A.1    Simpson, D.M.2    Qi, M.3    Elion, E.A.4
  • 16
    • 0030624529 scopus 로고    scopus 로고
    • Alternative yeast two-hybrid systems. The interaction trap and interaction mating
    • Golemis EA, Khazak V (1997) Alternative yeast two-hybrid systems. The interaction trap and interaction mating. Methods Mol Biol 63:197-218
    • (1997) Methods Mol Biol , vol.63 , pp. 197-218
    • Golemis, E.A.1    Khazak, V.2
  • 17
    • 0037131192 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor signaling by scaffold proteins
    • Hall RA, Lefkowitz RJ (2002) Regulation of G protein-coupled receptor signaling by scaffold proteins. Circ Res 91:672-680
    • (2002) Circ Res , vol.91 , pp. 672-680
    • Hall, R.A.1    Lefkowitz, R.J.2
  • 18
    • 0035960710 scopus 로고    scopus 로고
    • Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins
    • Harris K et al (2001) Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins. Curr Biol 11:1815-1824
    • (2001) Curr Biol , vol.11 , pp. 1815-1824
    • Harris, K.1
  • 20
    • 0030777328 scopus 로고    scopus 로고
    • Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: Application of a differential interaction trap assay for examining protein-protein interactions
    • Inouye C, Dhillon N, Durfee T, Zambryski PC, Thorner J (1997) Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: Application of a differential interaction trap assay for examining protein-protein interactions. Genetics 147:479-492
    • (1997) Genetics , vol.147 , pp. 479-492
    • Inouye, C.1    Dhillon, N.2    Durfee, T.3    Zambryski, P.C.4    Thorner, J.5
  • 21
    • 0031042444 scopus 로고    scopus 로고
    • Combinatorial control required for the specificity of yeast MAPK signaling
    • Madhani HD, Fink GR (1997) Combinatorial control required for the specificity of yeast MAPK signaling. Science 275:1314-1317
    • (1997) Science , vol.275 , pp. 1314-1317
    • Madhani, H.D.1    Fink, G.R.2
  • 22
    • 0030731714 scopus 로고    scopus 로고
    • MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    • Madhani HD, Styles CA, Fink GR (1997) MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 91:673-684
    • (1997) Cell , vol.91 , pp. 673-684
    • Madhani, H.D.1    Styles, C.A.2    Fink, G.R.3
  • 23
    • 0033588242 scopus 로고    scopus 로고
    • Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade
    • Mahanty SK, Wang Y, Farley FW, Elion EA (1999) Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade. Cell 98:501-512
    • (1999) Cell , vol.98 , pp. 501-512
    • Mahanty, S.K.1    Wang, Y.2    Farley, F.W.3    Elion, E.A.4
  • 24
    • 4744346430 scopus 로고    scopus 로고
    • Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast
    • Maleri S, Ge Q, Hackett EA, Wang Y, Dohlman HG, Errede B (2004) Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast. Mol Cell Biol 24:9221-9238
    • (2004) Mol Cell Biol , vol.24 , pp. 9221-9238
    • Maleri, S.1    Ge, Q.2    Hackett, E.A.3    Wang, Y.4    Dohlman, H.G.5    Errede, B.6
  • 25
    • 0027991228 scopus 로고
    • Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module
    • Marcus S, Polverino A, Barr M, Wigler M (1994) Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci USA 91:7762-7766
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7762-7766
    • Marcus, S.1    Polverino, A.2    Barr, M.3    Wigler, M.4
  • 26
    • 0023395343 scopus 로고
    • Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae
    • McCaffrey G, Clay FJ, Kelsay K, Sprague GF Jr (1987) Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae. Mol Cell Biol 7:2680-2690
    • (1987) Mol Cell Biol , vol.7 , pp. 2680-2690
    • McCaffrey, G.1    Clay, F.J.2    Kelsay, K.3    Sprague Jr., G.F.4
  • 27
    • 0344393408 scopus 로고    scopus 로고
    • Regulation of MAP kinase signaling modules by scaffold proteins in mammals
    • Morrison DK, Davis RJ (2003) Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 19:91-118
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 91-118
    • Morrison, D.K.1    Davis, R.J.2
  • 28
    • 0037436155 scopus 로고    scopus 로고
    • Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms
    • Park SH, Zarrinpar A, Lim WA (2003) Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299:1061-1064
    • (2003) Science , vol.299 , pp. 1061-1064
    • Park, S.H.1    Zarrinpar, A.2    Lim, W.A.3
  • 29
    • 0028046412 scopus 로고
    • Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
    • Printen JA, Sprague GF Jr (1994) Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138:609-619
    • (1994) Genetics , vol.138 , pp. 609-619
    • Printen, J.A.1    Sprague Jr., G.F.2
  • 30
    • 0034796049 scopus 로고    scopus 로고
    • Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation
    • Sabbagh W Jr, Flatauer LJ, Bardwell AJ, Bardwell L (2001) Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation. Mol Cell 8:683-691
    • (2001) Mol Cell , vol.8 , pp. 683-691
    • Sabbagh Jr., W.1    Flatauer, L.J.2    Bardwell, A.J.3    Bardwell, L.4
  • 31
    • 10944251582 scopus 로고    scopus 로고
    • Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae
    • Schwartz MA, Madhani HD (2004) Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae. Annu Rev Genet 38:725-748
    • (2004) Annu Rev Genet , vol.38 , pp. 725-748
    • Schwartz, M.A.1    Madhani, H.D.2
  • 32
    • 0033739255 scopus 로고    scopus 로고
    • Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein
    • Sette C, Inouye CJ, Stroschein SL, Iaquinta PJ, Thorner J (2000) Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell 11:4033-4049
    • (2000) Mol Biol Cell , vol.11 , pp. 4033-4049
    • Sette, C.1    Inouye, C.J.2    Stroschein, S.L.3    Iaquinta, P.J.4    Thorner, J.5
  • 33
    • 0030450397 scopus 로고    scopus 로고
    • Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction
    • Yablonski D, Marbach I, Levitzki A (1996) Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction. Proc Natl Acad Sci USA 93:13864-13869
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13864-13869
    • Yablonski, D.1    Marbach, I.2    Levitzki, A.3
  • 34
    • 0028884585 scopus 로고
    • Yeast MEK-dependent signal transduction: Response thresholds and parameters affecting fidelity
    • Yashar B et al (1995) Yeast MEK-dependent signal transduction: Response thresholds and parameters affecting fidelity. Mol Cell Biol 15:6545-6553
    • (1995) Mol Cell Biol , vol.15 , pp. 6545-6553
    • Yashar, B.1
  • 35
    • 0027499591 scopus 로고
    • Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases
    • Zhou Z, Gartner A, Cade R, Ammerer G, Errede B (1993) Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases. Mol Cell Biol 13:2069-2080
    • (1993) Mol Cell Biol , vol.13 , pp. 2069-2080
    • Zhou, Z.1    Gartner, A.2    Cade, R.3    Ammerer, G.4    Errede, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.