Structure of carbamoyl phosphate synthetase: A journey of 96 Å from substrate to product

Biochemistry

Volumn 36, Issue 21, 1997, Pages 6305-6316

  Thoden, James B ^a   Holden, Hazel M ^a   Wesenberg, Gary ^a   Raushel, Frank M ^b   Rayment, Ivan ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CARBAMOYL PHOSPHATE SYNTHASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC SITE; BINDING SITES; CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING); CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ORNITHINE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; URIDINE MONOPHOSPHATE;

EID: 0030957783     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970503q     Document Type: Article

References (59)

1. Anderson, P. M., and Meister, A. (1966) Biochemistry 5, 3164-3169.
2. Raushel, F. M., Anderson, P. M., and Villafranca, J. J. (1978) Biochemistry 17, 5587-5591.
3. Raushel, F. M., and Villafranca, J. J. (1979) Biochemistry 18, 3424-3429.
4. Braxton, B. L., Mullins, L. S., Raushel, F. M., and Reinhart, G. D. (1992) Biochemistry 31, 2309-2316.
5. Braxton, B. L., Mullins, L. S., Raushel, F. M., and Reinhart, G. D. (1996) Biochemistry 35, 11918-11924.
6. Anderson, P. M. (1995) in Nitrogen Metabolism and Excretion (Walsh, P. J., and Wright, P., Eds.) pp 33-49, CRC Press, Boca Raton, FL.
7. Matthews, S. L., and Anderson, P. M. (1972) Biochemistry 11, 1176-1183.
8. Trotta, P. P., Burt, M. E., Haschemeyer, R. H., and Meister, A. (1971) Proc. Natl. Acad. Sci. U.S.A. 68, 2599-2603.
9. Nyunoya, H., and Lusty, C. J. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 4629-4633.
10. Piette, J., Nyunoya, H., Lusty, C. J., Cunin, R., Weyens, G., Crabeel, M., Charlier, D., Glansdorff, N., and Pierard, A. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 4134-4138.
11. Rubino, S. D., Nyunoya, H., and Lusty, C. J. (1986) J. Biol. Chem. 261, 11320-11327.
12. Post, L. E., Post, D. J., and Raushel, F. M. (1990) J. Biol. Chem. 265, 7742-7747.
13. Miles, B. W., Mareya, S. M., Post, L. E., Post, D. J., Chang, S. H., and Raushel, F. M. (1993) Biochemistry 32, 232-240.
14. Javid-Majd, F., Stapleton, M. A., Harmon, M. F., Hanks, B. A., Mullins, L. S., and Raushel, F. M. (1996) Biochemistry 35, 14362-14369.
15. Stapleton, M. A., Javid-Majd, F., Harmon, M. F., Hanks, B. A., Grahmann, J. L., Mullins, L. S., and Raushel, F. M. (1996) Biochemistry 35, 14352-14361.
16. Mareya, S. M., and Raushel, F. M. (1994) Biochemistry 33, 2945-2950.
17. Thoden, J. B., Raushel, F. M., Mareya, S., Tomchick, D., and Rayment, I. (1995) Acta Crystallogr. D 51, 827-829.
18. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 67-71.
19. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 916-924.
20. Wesenberg, G., and Rayment, I. (1997) manuscript in preparation.
21. Terwilliger, T. C., and Eisenberg, D. (1983) Acta Crystallogr. A 39, 813-817.
22. Wang, B. C. (1985) in Methods in Enzymology (Wickoff, H. W., Hirs, C. H. W., and Timasheff, S. N., Eds.) pp 90-112, Academic Press, San Diego.
23. Rould, M. A., Perona, J. J., Soll, D., and Steitz, T. A. (1989) Science 246, 1135-1142.
24. Bricogne, G. (1976) Acta Crystallogr. A 32, 832-847.
25. Tronrud, D. E., Ten Eyck, L. F., and Matthews, B. W. (1987) Acta Crystallogr. A 43, 489-501.
26. Read, R. J. (1986) Acta Crystallogr. A 42, 140-149.
27. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
28. Powers, S. G., Meister, A., and Haschemeyer, R. H. (1980) J. Biol. Chem. 255, 1554-1558.
29. Anderson, P. M. (1986) Biochemistry 25, 5576-5582.
30. Rubio, V., Cervera, J., Lusty, C. J., Bendala, E., and Britton, H. G. (1991) Biochemistry 30, 1068-1075.
31. Liu, X., Guy, H. I., and Evans, D. R. (1994) J. Biol. Chem. 269, 27747-27755.
32. Czerwinski, R. M., Mareya, S. M., and Raushel, F. M. (1995) Biochemistry 34, 13920-13927.
33. Cervera, J., Bendala, E., Britton, H. G., Bueso, J., Nassif, Z., Lusty, C. J., and Rubio, V. (1996) Biochemistry 35, 7247-7255.
34. Zhang, X.-J., and Matthews, B. W. (1995) J. Appl. Crystallogr. 28, 624-630.
35. Tesmer, J. J. G., Klem, T. J., Deras, M. L., Davisson, V. J., and Smith, J. L. (1996) Nat. Struct. Biol. 3, 74-86.
36. Rossmann, M. G., and Argos, P. (1975) J. Biol. Chem. 250, 7525-7532.
37. Meister, A. (1989) in Advances in Enzymology and Related Areas of Molecular Biology (Meister, A., Ed.) Vol. 62, pp 315-374, Wiley, New York.
38. Rubino, S. D., Nyunoya, H., and Lusty, C. J. (1987) J. Biol. Chem. 262, 4382-4386.
39. Mullins, L. S., Lusty, C. J., and Raushel, F. M. (1991) J. Biol. Chem. 266, 8236-8240.
40. Lusty, C. J. (1992) FEBS Lett. 314, 135-138.
41. Zalkin, H. (1993) Adv. Enzymol. Relat. Areas Mol. Biol. 66, 203-309.
42. Miran, S. G., Chang, S. H., and Raushel, F. M. (1991) Biochemistry 30, 7901-7907.
43. Ogita, T., and Knowles, J. R. (1988) Biochemistry 27, 8028-8033.
44. Waldrop, G. L., Rayment, I., and Holden, H. M. (1994) Biochemistry 33, 10249-10256.
45. Fan, C., Moews, P. C., Walsh, C. T., and Knox, J. R. (1994) Science 266, 439-443.
46. Yamaguchi, H., Kato, H., Hata, Y., Nishioka, T., Kimura, A., Oda, J., and Katsube, Y. (1993) J. Mol. Biol. 229, 1083-1100.
47. Wolodko, W. T., Fraser, M. E., James, M. N. G., and Bridger, W. A. (1994) J. Biol. Chem. 269, 10883-10890.
48. Rossmann, M. G., Liljas, A., Branden, C.-I., and Banaszak, L. J. (1975) in The Enzymes (Boyer, P. D., Ed.) pp 61-101, Academic Press, New York.
49. Anderson, P. M., and Meister, A. (1966) Biochemistry 5, 3157-3163.
50. Pierard, A. (1966) Science 154, 1572-1573.
51. Anderson, P. M., and Meister, A. (1965) Biochemistry 4, 2803-2809.
52. Wang, T. T., Bishop, S. H., and Himoe, A. (1972) J. Biol. Chem. 247, 4437-4440.
53. Sauers, C. K., Jencks, W. P., and Groh, S. (1975) J. Am. Chem. Soc. 97, 5546.
54. Raushel, F. M., Rawding, C. J., Anderson, P. M., and Villafranca, J. J. (1979) Biochemistry 18, 5562-5566.
55. Srere, P. A. (1987) Annu. Rev. Biochem. 56, 89-124.
56. Hyde, C. C., Ahmed, S. A., Padlan, E. A., Miles, E. W., and Davies, D. R. (1988) J. Biol. Chem. 263, 17857-17871.
57. Pan, P., Woehl, E., and Dunn, M. (1997) Trends Biochem. Sci. 22, 22-27.
58. Wesenberg, G. (1997) University of Wisconsin, Madison, WI.
59. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.