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Volumn 9, Issue 2, 2011, Pages 102-122

Pharmacoproteomics applications for drug target discovery in CNS disorders

Author keywords

CNS; Diagnostic medicine; Drug targets; Personalized medicine; Pharmacoproteomic

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 4 AMINO 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID 2,2 DIOXIDE; 4 [2 AMINO 4 (METHYLTHIO)BUTYRYLAMINO] 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID 2,2 DIOXIDE; 8 (2,4 DICHLOROPHENYL) 4 [2 METHOXY 1 (METHOXYMETHYL)ETHYLAMINO] 2,7 DIMETHYLPYRAZOLO[1,5 A][1,3,5]TRIAZINE; APOMORPHINE; ARIPIPRAZOLE; BROMOCRIPTINE; CARBAMAZEPINE; CHLORPROMAZINE; CLOZAPINE; CX 614; ESCITALOPRAM; FLUOXETINE; GAMBOGIC ACID; HALOPERIDOL; LEVODOPA; LITHIUM; MEMANTINE; N [2 [4 (3 THIENYL)PHENYL]PROPYL] 2 PROPANESULFONAMIDE; OLANZAPINE; PALIPERIDONE; PERGOLIDE; QUETIAPINE; RILUZOLE; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VENLAFAXINE; VOFOPITANT;

EID: 79955677442     PISSN: 18756921     EISSN: 18756913     Source Type: Journal    
DOI: 10.2174/187569211795508484     Document Type: Review
Times cited : (1)

References (210)
  • 1
    • 77249179997 scopus 로고    scopus 로고
    • An update on clinical proteomics in Alzheimer's research
    • Korolainen MA, Nyman TA, Aittokallio T, et al. An update on clinical proteomics in Alzheimer's research. J Neurochem 2010;112: 1386-414.
    • (2010) J Neurochem , vol.112 , pp. 1386-1414
    • Korolainen, M.A.1    Nyman, T.A.2    Aittokallio, T.3
  • 2
    • 31344462620 scopus 로고    scopus 로고
    • Age-related neuropathology, cognitive decline, and Alzheimer's disease
    • Keller JN. Age-related neuropathology, cognitive decline, and Alzheimer's disease. Ageing Res Rev 2006; 5: 1-13.
    • (2006) Ageing Res Rev , vol.5 , pp. 1-13
    • Keller, J.N.1
  • 3
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • Schneider JA, Arvanitakis Z, Bang W, et al. Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology 2007; 69: 2197-204.
    • (2007) Neurology , vol.69 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3
  • 4
    • 57649129041 scopus 로고    scopus 로고
    • Target identification for CNS diseases by transcriptional profiling
    • Altar CA, Vawter MP, Ginsberg SD. Target identification for CNS diseases by transcriptional profiling. Neuropsychopharmacology 2009; 34(1): 18-54.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 18-54
    • Altar, C.A.1    Vawter, M.P.2    Ginsberg, S.D.3
  • 5
    • 0034319169 scopus 로고    scopus 로고
    • Role of calcium in neuronal cell injury: Which subcellular compartment is involved?
    • Paschen W. Role of calcium in neuronal cell injury: which subcellular compartment is involved? Brain Res Bul 2000; 53: 409-13.
    • (2000) Brain Res Bul , vol.53 , pp. 409-413
    • Paschen, W.1
  • 7
    • 23144463734 scopus 로고    scopus 로고
    • Alzheimer's diseaseassociated neurotoxic mechanisms and neuroprotective strategies
    • Pereira C, Agostinho P, Moreira PI, et al. Alzheimer's diseaseassociated neurotoxic mechanisms and neuroprotective strategies. Curr Drug Targets CNS Neurol Disord 2005; 4: 383-403.
    • (2005) Curr Drug Targets CNS Neurol Disord , vol.4 , pp. 383-403
    • Pereira, C.1    Agostinho, P.2    Moreira, P.I.3
  • 8
    • 33847613885 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer'sdisease
    • Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer'sdisease. J Neuroimmunol 2007; 184: 69-91.
    • (2007) J Neuroimmunol , vol.184 , pp. 69-91
    • Heneka, M.T.1    O'Banion, M.K.2
  • 9
    • 39849110726 scopus 로고    scopus 로고
    • The GSK3 hypothesis of Alzheimer'sdisease
    • Hooper C, Killick R, Lovestone S. The GSK3 hypothesis of Alzheimer'sdisease. J Neurochem 2008; 104: 1433-9.
    • (2008) J Neurochem , vol.104 , pp. 1433-1439
    • Hooper, C.1    Killick, R.2    Lovestone, S.3
  • 10
    • 70449348828 scopus 로고    scopus 로고
    • Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease
    • Alex ER, Chera LM, Lucia IS, et al. Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Biomarkers 2009; 14(7): 493-501.
    • (2009) Biomarkers , vol.14 , Issue.7 , pp. 493-501
    • Alex, E.R.1    Chera, L.M.2    Lucia, I.S.3
  • 11
    • 0028287485 scopus 로고
    • Alzheimer brain proteins investigated by twodimensional gel electrophoresis with immobilized pH gradients in the first dimension
    • Mattila KM, Frey H. Alzheimer brain proteins investigated by twodimensionalgel electrophoresis with immobilized pH gradients in the first dimension. Electrophoresis 1994; 15: 721-5.
    • (1994) Electrophoresis , vol.15 , pp. 721-725
    • Mattila, K.M.1    Frey, H.2
  • 12
    • 79954430630 scopus 로고    scopus 로고
    • Human Alzheimer's disease synaptic O-GlcNAc site mapping and iTRAQ expression proteomics with ion trap mass spectrometry
    • Yuliya VS, John D, Jared AB, et al. Human Alzheimer's diseasesynaptic O-GlcNAc site mapping and iTRAQ expression proteomicswith ion trap mass spectrometry. Amino Acids 2011;40(3): 765-79.
    • (2011) Amino Acids , vol.40 , Issue.3 , pp. 765-779
    • Yuliya, V.S.1    John, D.2    Jared, A.B.3
  • 13
    • 70349984556 scopus 로고    scopus 로고
    • Proteomics in human Parkinson's disease research
    • Virginie L, Enikö K, Denis FH, et al. Proteomics in human Parkinson's disease research. J Proteomics 2009; 73(1): 10-29.
    • (2009) J Proteomics , vol.73 , Issue.1 , pp. 10-29
    • Virginie, L.1    Enikö, K.2    Denis, F.H.3
  • 14
    • 33748325848 scopus 로고    scopus 로고
    • Decreased alpha-synucleinin cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
    • Tokuda T, Salem SA, Allsop D, et al. Decreased alpha-synucleinin cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 2006; 349:162-6.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 162-166
    • Tokuda, T.1    Salem, S.A.2    Allsop, D.3
  • 15
    • 33646833404 scopus 로고    scopus 로고
    • Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease
    • Waragai M, Wei J, Fujita M, et al. Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease. Biochem Biophys Res Commun 2006; 345: 967-72.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 967-972
    • Waragai, M.1    Wei, J.2    Fujita, M.3
  • 16
    • 0021628758 scopus 로고
    • Two-dimensional electrophoresis and "ultrasensitive" silver staining of cerebrospinal fluid proteins in neurological diseases
    • Harrington MG, Merril CR. Two-dimensional electrophoresis and "ultrasensitive" silver staining of cerebrospinal fluid proteins inneurological diseases. Clin Chem 1984; 30: 1933-7.
    • (1984) Clin Chem , vol.30 , pp. 1933-1937
    • Harrington, M.G.1    Merril, C.R.2
  • 17
    • 33747409456 scopus 로고    scopus 로고
    • Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders
    • Abdi F, Quinn JF, Jankovic J, et al. Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis 2006;9: 293-348.
    • (2006) J Alzheimers Dis , vol.9 , pp. 293-348
    • Abdi, F.1    Quinn, J.F.2    Jankovic, J.3
  • 18
    • 33644903466 scopus 로고    scopus 로고
    • Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease
    • Goldknopf IL, Sheta EA, Bryson J, et al. Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease. Biochem Biophys Res Commun 2006; 342:1034-9.
    • (2006) Biochem Biophys Res Commun , vol.342 , pp. 1034-1039
    • Goldknopf, I.L.1    Sheta, E.A.2    Bryson, J.3
  • 19
    • 10644277894 scopus 로고    scopus 로고
    • Proteome analysis of human substantia nigra in Parkinson's disease
    • Basso M, Giraudo S, Corpillo D, et al. Proteome analysis of human substantia nigra in Parkinson's disease. Proteomics 2004; 4: 3943-52.
    • (2004) Proteomics , vol.4 , pp. 3943-3952
    • Basso, M.1    Giraudo, S.2    Corpillo, D.3
  • 20
    • 77950862634 scopus 로고    scopus 로고
    • Cloning, characterization,and functional studies of a human 40-kDa catecholamineregulated protein: Implications in central nervous system disorders
    • Gabriele J, Pontoriero GF, Thomas N, et al. Cloning, characterization,and functional studies of a human 40-kDa catecholamineregulatedprotein: implications in central nervous system disorders. Cell Stress Chaperones 2009; 14: 555-67.
    • (2009) Cell Stress Chaperones , vol.14 , pp. 555-567
    • Gabriele, J.1    Pontoriero, G.F.2    Thomas, N.3
  • 21
    • 42649111286 scopus 로고    scopus 로고
    • Proteomic identification of novelproteins associated with Lewy bodies
    • Xia Q, Liao L, Cheng D, et al. Proteomic identification of novelproteins associated with Lewy bodies. Front Biosci 2008; 13: 3850-6.
    • (2008) Front Biosci , vol.13 , pp. 3850-3856
    • Xia, Q.1    Liao, L.2    Cheng, D.3
  • 22
    • 67649226736 scopus 로고    scopus 로고
    • Proteomic analysis of dorsolateral prefrontal cortex indicates the involvementof cytoskeleton, oligodendrocyte, energy metabolism and newpotential markers in schizophrenia
    • Martins-de-Souza D, Gattaz WF, Schmitt A, et al. Proteomicanalysis of dorsolateral prefrontal cortex indicates the involvementof cytoskeleton, oligodendrocyte, energy metabolism and newpotential markers in schizophrenia. J Psychiatr Res 2009; 43:978-86.
    • (2009) J Psychiatr Res , vol.43 , pp. 978-986
    • Martins-de-Souza, D.1    Gattaz, W.F.2    Schmitt, A.3
  • 23
    • 66149176937 scopus 로고    scopus 로고
    • Proteome analysis of schizophrenia patients Wernicke's area reveals anenergy metabolism dysregulation
    • Martins-de-Souza D, Gattaz WF, Schmitt A, et al. Proteome analysis of schizophrenia patients Wernicke's area reveals anenergy metabolism dysregulation. BMC Psychiatry 2009; 9: 17.
    • (2009) BMC Psychiatry , vol.9 , pp. 17
    • Martins-de-Souza, D.1    Gattaz, W.F.2    Schmitt, A.3
  • 24
    • 3142745187 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: Evidence for compromised brain metabolism and oxidative stress
    • Prabakaran S, Swatton JE, Ryan MM, et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 2004; 9: 684-97.
    • (2004) Mol Psychiatry , vol.9 , pp. 684-697
    • Prabakaran, S.1    Swatton, J.E.2    Ryan, M.M.3
  • 25
    • 33745095612 scopus 로고    scopus 로고
    • Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes
    • Beasley CL, Pennington K, Behan A, et al. Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders:evidence for disease-associated changes. Proteomics 2006; 6:3414-25.
    • (2006) Proteomics , vol.6 , pp. 3414-3425
    • Beasley, C.L.1    Pennington, K.2    Behan, A.3
  • 26
    • 67650726655 scopus 로고    scopus 로고
    • 2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease
    • English JA, Dicker P, Föcking M, et al. 2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease. Proteomics 2009; 9: 3368-82.
    • (2009) Proteomics , vol.9 , pp. 3368-3382
    • English, J.A.1    Dicker, P.2    Föcking, M.3
  • 27
    • 0032866654 scopus 로고    scopus 로고
    • Three-dimensionalanalysis with MRI and PET of the size, shape, and function of the thalamus in the schizophrenia spectrum
    • Hazlett EA, Buchsbaum MS, Byne W, et al. Three-dimensionalanalysis with MRI and PET of the size, shape, and function of the thalamus in the schizophrenia spectrum. Am J Psychiatry 1999;156: 1190-9.
    • (1999) Am J Psychiatry , vol.156 , pp. 1190-1199
    • Hazlett, E.A.1    Buchsbaum, M.S.2    Byne, W.3
  • 28
    • 0026659790 scopus 로고
    • Limbic systemabnormalities identified in schizophrenia using positron emissiontomography with fluorodeoxyglucose and neocortical alterationswith deficit syndrome
    • Tamminga CA, Thaker GK, Buchanan R, et al. Limbic systemabnormalities identified in schizophrenia using positron emissiontomography with fluorodeoxyglucose and neocortical alterationswith deficit syndrome. Arch Gen Psychiatry 1992; 49: 522-30.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 522-530
    • Tamminga, C.A.1    Thaker, G.K.2    Buchanan, R.3
  • 29
    • 0036902639 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: Apossible linkage to dopamine
    • Ben-Shachar D. Mitochondrial dysfunction in schizophrenia: apossible linkage to dopamine. J Neurochem 2002; 83: 1241-51.
    • (2002) J Neurochem , vol.83 , pp. 1241-1251
    • Ben-Shachar, D.1
  • 32
    • 56449084674 scopus 로고    scopus 로고
    • Independent proteinprofilingstudies show a decrease in apolipoprotein A1 levels inschizophrenia CSF, brain and peripheral tissues
    • Huang JT, Wang L, Prabakaran S, et al. Independent proteinprofilingstudies show a decrease in apolipoprotein A1 levels inschizophrenia CSF, brain and peripheral tissues. Mol Psychiatry 2008; 13(12): 1118-28.
    • (2008) Mol Psychiatry , vol.13 , Issue.12 , pp. 1118-1128
    • Huang, J.T.1    Wang, L.2    Prabakaran, S.3
  • 33
    • 77958496632 scopus 로고    scopus 로고
    • Global proteomic profilingreveals altered proteomic signature in schizophrenia serum
    • Levin Y, Wang L, Schwarz E, et al. Global proteomic profilingreveals altered proteomic signature in schizophrenia serum. Mol Psychiatry 2009; 15: 1088-100.
    • (2009) Mol Psychiatry , vol.15 , pp. 1088-1100
    • Levin, Y.1    Wang, L.2    Schwarz, E.3
  • 34
    • 33846609097 scopus 로고    scopus 로고
    • 2-D DIGEanalysis of liver and red blood cells provides further evidence foroxidative stress in schizophrenia
    • Prabakaran S, Wengenroth M, Lockstone HE, et al. 2-D DIGEanalysis of liver and red blood cells provides further evidence foroxidative stress in schizophrenia. J Proteome Res 2007; 6: 141-9.
    • (2007) J Proteome Res , vol.6 , pp. 141-149
    • Prabakaran, S.1    Wengenroth, M.2    Lockstone, H.E.3
  • 35
    • 33751002650 scopus 로고    scopus 로고
    • Normalization and expressionchanges in predefined sets of proteins using 2D gel electrophoresis:A proteomic study of L-DOPA induced dyskinesia in an animalmodel of Parkinson's disease using DIGE
    • Kultima K, Scholz B, Alm H, et al. Normalization and expressionchanges in predefined sets of proteins using 2D gel electrophoresis:a proteomic study of L-DOPA induced dyskinesia in an animalmodel of Parkinson's disease using DIGE. BMC Bioinformatics 2006; 7: 475.
    • (2006) BMC Bioinformatics , vol.7 , pp. 475
    • Kultima, K.1    Scholz, B.2    Alm, H.3
  • 36
    • 77949444966 scopus 로고    scopus 로고
    • Plasma Protein Biomarkersfor Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections
    • Domenici E, Wille DR, Tozzi F, et al. Plasma Protein Biomarkersfor Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections. PLoS ONE 2010; 5(2): e9166.
    • (2010) PLoS ONE , vol.5 , Issue.2
    • Domenici, E.1    Wille, D.R.2    Tozzi, F.3
  • 37
    • 34648843243 scopus 로고    scopus 로고
    • Pathologically activated therapeutics for neuroprotection
    • Lipton SA. Pathologically activated therapeutics for neuroprotection. Nat Rev Neurosci 2007; 8: 803-8.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 803-808
    • Lipton, S.A.1
  • 38
    • 36049003755 scopus 로고    scopus 로고
    • Gambogic amide, a selectiveagonist for TrkA receptor that possesses robust neurotrophic activity,prevents neuronal cell death
    • Jang SW, Okada M, Sayeed I, et al. Gambogic amide, a selectiveagonist for TrkA receptor that possesses robust neurotrophic activity,prevents neuronal cell death. Proc Natl Acad Sci USA 2007;104(41): 16329-34.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.41 , pp. 16329-16334
    • Jang, S.W.1    Okada, M.2    Sayeed, I.3
  • 39
    • 0025933802 scopus 로고
    • Electroconvulsive therapy in Parkinson's disease and other movement disorders
    • Faber R, Trimble MR. Electroconvulsive therapy in Parkinson's disease and other movement disorders. Mov Disord 1991; 6(4):293-303.
    • (1991) Mov Disord , vol.6 , Issue.4 , pp. 293-303
    • Faber, R.1    Trimble, M.R.2
  • 40
    • 65649103652 scopus 로고    scopus 로고
    • Proteomic Analysis of Rat Brains Following Exposure to Electroconvulsive Therapy
    • Lee CS, Kang KR, Lee JY, et al. Proteomic Analysis of Rat Brains Following Exposure to Electroconvulsive Therapy. J Korean MedSci 2009; 24: 132-7.
    • (2009) J Korean MedSci , vol.24 , pp. 132-137
    • Lee, C.S.1    Kang, K.R.2    Lee, J.Y.3
  • 41
    • 0034995073 scopus 로고    scopus 로고
    • S100: A multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
    • Donato R. S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 2001; 33: 637-68.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 637-668
    • Donato, R.1
  • 42
    • 6044238142 scopus 로고    scopus 로고
    • Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF
    • Rothermundt M, Falkai P, Ponath G, et al. Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF. Mol Psychiatry 2004; 9: 897-9.
    • (2004) Mol Psychiatry , vol.9 , pp. 897-899
    • Rothermundt, M.1    Falkai, P.2    Ponath, G.3
  • 43
    • 0031470652 scopus 로고    scopus 로고
    • The structural basis for 14-3-3: Phosphopeptide binding specificity
    • Yaffe MB, Rittinger K, Volinia S, et al. The structural basis for 14-3-3: phosphopeptide binding specificity. Cell 1997; 91: 961-71.
    • (1997) Cell , vol.91 , pp. 961-971
    • Yaffe, M.B.1    Rittinger, K.2    Volinia, S.3
  • 44
    • 20444431866 scopus 로고    scopus 로고
    • Phosphorylation of Grb10regulates its interaction with 14-3-3
    • Urschel S, Bassermann F, Bai RY, et al. Phosphorylation of Grb10regulates its interaction with 14-3-3. J Biol Chem 2005; 280:16987-93.
    • (2005) J Biol Chem , vol.280 , pp. 16987-16993
    • Urschel, S.1    Bassermann, F.2    Bai, R.Y.3
  • 45
    • 0034606331 scopus 로고    scopus 로고
    • Systematic screening of the 14-3-3eta (n) chain gene for polymorphic variants and case-control analysis in schizophrenia
    • Bell R, Munro J, Russ C, et al. Systematic screening of the 14-3-3eta (n) chain gene for polymorphic variants and case-control analysis in schizophrenia. Am J Med Genet 2000; 96: 736-43.
    • (2000) Am J Med Genet , vol.96 , pp. 736-743
    • Bell, R.1    Munro, J.2    Russ, C.3
  • 46
    • 0035878139 scopus 로고    scopus 로고
    • Application of cDN Amicroarrays to examine gene expression differences in schizophrenia
    • Vawter MP, Barrett T, Cheadle C, et al. Application of cDN Amicroarrays to examine gene expression differences in schizophrenia. Brain Res Bull 2001; 55: 641-50.
    • (2001) Brain Res Bull , vol.55 , pp. 641-650
    • Vawter, M.P.1    Barrett, T.2    Cheadle, C.3
  • 47
    • 0037223552 scopus 로고    scopus 로고
    • Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3eta gene
    • Wong AH, Macciardi F, Klempan T, et al. Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3eta gene. Mol Psychiatry 2003;8: 156-66.
    • (2003) Mol Psychiatry , vol.8 , pp. 156-166
    • Wong, A.H.1    Macciardi, F.2    Klempan, T.3
  • 48
    • 0034093383 scopus 로고    scopus 로고
    • Proteomics in molecular medicine: Applications in central nervous systems disorders
    • Rohlff C. Proteomics in molecular medicine: applications in central nervous systems disorders. Electrophoresis 2000; 21: 1227-34.
    • (2000) Electrophoresis , vol.21 , pp. 1227-1234
    • Rohlff, C.1
  • 49
    • 34547467205 scopus 로고    scopus 로고
    • Proteomic analysis of striatal proteins in the rat model of L-DOPA-induced dyskinesia
    • Valastro B, Dekundy A, Krogh M, et al. Proteomic analysis of striatal proteins in the rat model of L-DOPA-induced dyskinesia. J Neurochem 2007; 102: 1395-409.
    • (2007) J Neurochem , vol.102 , pp. 1395-1409
    • Valastro, B.1    Dekundy, A.2    Krogh, M.3
  • 50
    • 0027391629 scopus 로고
    • Small heat shock proteins are molecular chaperones
    • Jakob U, Gaestel M, Engel K, et al. Small heat shock proteins are molecular chaperones. J Biol Chem 1993; 268: 1517-20.
    • (1993) J Biol Chem , vol.268 , pp. 1517-1520
    • Jakob, U.1    Gaestel, M.2    Engel, K.3
  • 51
    • 0027284704 scopus 로고
    • Immunohistochemical localization of adherens junction components in blood-brain barrier microvessels of the rat
    • Schulze C, Firth JA. Immunohistochemical localization of adherens junction components in blood-brain barrier microvessels of the rat. J Cell Sci 1993; 104(3): 773-82.
    • (1993) J Cell Sci , vol.104 , Issue.3 , pp. 773-782
    • Schulze, C.1    Firth, J.A.2
  • 52
    • 0028068121 scopus 로고
    • Bromocriptine protectsmice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro
    • Ogawa N, Tanaka K, Asanuma M, et al. Bromocriptine protectsmice against 6-hydroxydopamine and scavenges hydroxyl freeradicals in vitro. Brain Res 1994; 657: 207-13.
    • (1994) Brain Res , vol.657 , pp. 207-213
    • Ogawa, N.1    Tanaka, K.2    Asanuma, M.3
  • 53
    • 0027953004 scopus 로고
    • Antioxidant properties of bromocriptine, a dopamine agonist
    • Yoshikawa T, Minamiyama Y, Naito Y, et al. Antioxidant properties of bromocriptine, a dopamine agonist. J Neurochem 1994; 62:1034-8.
    • (1994) J Neurochem , vol.62 , pp. 1034-1038
    • Yoshikawa, T.1    Minamiyama, Y.2    Naito, Y.3
  • 54
    • 0031927090 scopus 로고    scopus 로고
    • Dopamine D2-type agonistsprotect mesencephalic neurons from glutamate neurotoxicity:Mechanisms of neuroprotective treatment against oxidative stress
    • Sawada H, Ibi M, Kihara T, et al. Dopamine D2-type agonistsprotect mesencephalic neurons from glutamate neurotoxicity:mechanisms of neuroprotective treatment against oxidative stress. Ann Neurol 1998; 44: 110-9.
    • (1998) Ann Neurol , vol.44 , pp. 110-119
    • Sawada, H.1    Ibi, M.2    Kihara, T.3
  • 55
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends Neurosci 1989; 12(10): 366-75.
    • (1989) Trends Neurosci , vol.12 , Issue.10 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 56
    • 42449149436 scopus 로고    scopus 로고
    • Striatal Proteomic Analysis Suggests that First L-Dopa Dose Equates to Chronic Exposure
    • Scholz B, Svensson M, Alm H, et al. Striatal Proteomic Analysis Suggests that First L-Dopa Dose Equates to Chronic Exposure. PLoS ONE 2008; 3(2): e1589.
    • (2008) PLoS ONE , vol.3 , Issue.2
    • Scholz, B.1    Svensson, M.2    Alm, H.3
  • 57
    • 33750068268 scopus 로고    scopus 로고
    • Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice
    • Rojo AI, Montero C, Salazar M, et al. Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice. Eur J Neurosci 2006; 24(7): 1874-84.
    • (2006) Eur J Neurosci , vol.24 , Issue.7 , pp. 1874-1884
    • Rojo, A.I.1    Montero, C.2    Salazar, M.3
  • 58
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston JW, Ballard P, Tetrud JW, et al. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983; 219: 979-80.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3
  • 59
    • 0035344211 scopus 로고    scopus 로고
    • Experimental models of Parkinson's disease
    • Beal MF. Experimental models of Parkinson's disease. Nat Rev Neurosci 2001; 2: 325-34.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 325-334
    • Beal, M.F.1
  • 60
    • 77949865344 scopus 로고    scopus 로고
    • Region-Specific Protein Abundance Changes in the Brain of MPTP-Induced Parkinson's Disease Mouse Model
    • Zhang X, Zhou JY, Chin MH, et al. Region-Specific Protein Abundance Changes in the Brain of MPTP-Induced Parkinson's Disease Mouse Model. J Proteome Res 2010; 9: 1496-509.
    • (2010) J Proteome Res , vol.9 , pp. 1496-1509
    • Zhang, X.1    Zhou, J.Y.2    Chin, M.H.3
  • 61
    • 0032527596 scopus 로고    scopus 로고
    • L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons
    • Hulley P, Schachner M, Lubbert H. L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons. J Neurosci Res 1998; 53: 129-34.
    • (1998) J Neurosci Res , vol.53 , pp. 129-134
    • Hulley, P.1    Schachner, M.2    Lubbert, H.3
  • 62
    • 15244346626 scopus 로고    scopus 로고
    • Signal transduction pathways implicated in neural recognition molecule L1 triggered neuroprotection and neuritogenesis
    • Loers G, Chen S, Grumet M, et al. Signal transduction pathways implicated in neural recognition molecule L1 triggered neuroprotection and neuritogenesis. J Neurochem 2005; 92: 1463-76.
    • (2005) J Neurochem , vol.92 , pp. 1463-1476
    • Loers, G.1    Chen, S.2    Grumet, M.3
  • 63
    • 33845882730 scopus 로고    scopus 로고
    • Neural recognition molecules of the immunoglobulin superfamily: Signaling transducers of axonguidance and neuronal migration
    • Maness PF, Schachner M. Neural recognition molecules of the immunoglobulin superfamily: Signaling transducers of axonguidance and neuronal migration. Nat Neurosci 2007; 10: 19-26.
    • (2007) Nat Neurosci , vol.10 , pp. 19-26
    • Maness, P.F.1    Schachner, M.2
  • 64
    • 0344393011 scopus 로고    scopus 로고
    • Decreased anxiety, altered placelearning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion moleculeL1
    • Law JW, Lee AY, Sun M, et al. Decreased anxiety, altered placelearning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion moleculeL1. J Neurosci 2003; 23: 10419-32.
    • (2003) J Neurosci , vol.23 , pp. 10419-10432
    • Law, J.W.1    Lee, A.Y.2    Sun, M.3
  • 65
    • 41549132572 scopus 로고    scopus 로고
    • Proteome analysis of ventral midbrain in MPTP-treated normal and L1cam transgenicmice
    • Diedrich M, Mao L, Bernreuther C, et al. Proteome analysis of ventral midbrain in MPTP-treated normal and L1cam transgenicmice. Proteomics 2008; 8: 1266-75.
    • (2008) Proteomics , vol.8 , pp. 1266-1275
    • Diedrich, M.1    Mao, L.2    Bernreuther, C.3
  • 66
    • 39749144048 scopus 로고    scopus 로고
    • Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis Revealed by Proteomic and Transcriptomic Analyses of the Striata in Two Mouse Models of Parkinson'sDisease
    • Chin MH, Qian WJ, Wang H, et al. Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis Revealed by Proteomic and Transcriptomic Analyses of the Striata in Two Mouse Models of Parkinson'sDisease. J Proteome Res 2008; 7: 666-77.
    • (2008) J Proteome Res , vol.7 , pp. 666-677
    • Chin, M.H.1    Qian, W.J.2    Wang, H.3
  • 67
    • 0037349788 scopus 로고    scopus 로고
    • Acupuncture prevents 6-hydroxydopamine-induced neuronal death in the nigrostriataldopaminergic system in the rat Parkinson's disease model
    • Park HJ, Lim S, Joo WS, et al. Acupuncture prevents 6-hydroxydopamine-induced neuronal death in the nigrostriataldopaminergic system in the rat Parkinson's disease model. Exp Neurol 2003; 180: 93-8.
    • (2003) Exp Neurol , vol.180 , pp. 93-98
    • Park, H.J.1    Lim, S.2    Joo, W.S.3
  • 68
    • 33947600735 scopus 로고    scopus 로고
    • The effect of manual acupuncture therapy on symptoms of the patients with idiopathic Parkinson's disease
    • Ha JY, Lee SH, Yin CS, et al. The effect of manual acupuncture therapy on symptoms of the patients with idiopathic Parkinson's disease. J Korean Orient Med 2003; 24: 172-83.
    • (2003) J Korean Orient Med , vol.24 , pp. 172-183
    • Ha, J.Y.1    Lee, S.H.2    Yin, C.S.3
  • 69
    • 33846027543 scopus 로고    scopus 로고
    • Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model
    • Kang JM, Park HJ, Choi YG, et al. Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model. Brain Res 2007; 1131: 211-9.
    • (2007) Brain Res , vol.1131 , pp. 211-219
    • Kang, J.M.1    Park, H.J.2    Choi, Y.G.3
  • 70
    • 33744458703 scopus 로고    scopus 로고
    • Open-label trial regardingthe use of acupuncture and yin tui na in Parkinson's disease outpatients:A pilot study on efficacy, tolerability, and quality of life
    • Eng ML, Lyons KE, Greene MS, et al. Open-label trial regardingthe use of acupuncture and yin tui na in Parkinson's disease outpatients:A pilot study on efficacy, tolerability, and quality of life. J Altern Complemen Med 2006; 12: 395-9.
    • (2006) J Altern Complemen Med , vol.12 , pp. 395-399
    • Eng, M.L.1    Lyons, K.E.2    Greene, M.S.3
  • 71
    • 27744447542 scopus 로고    scopus 로고
    • Evaluation of acupuncture in the treatment of Parkinson's disease: A double-blind pilot study
    • Cristian A, Katz M, Cutrone E, et al. Evaluation of acupuncture in the treatment of Parkinson's disease: A double-blind pilot study. Mov Disord 2005; 20: 1185-8.
    • (2005) Mov Disord , vol.20 , pp. 1185-1188
    • Cristian, A.1    Katz, M.2    Cutrone, E.3
  • 72
    • 55849130699 scopus 로고    scopus 로고
    • Proteomic analysis of the neuroprotective mechanisms of acupuncture treatment in a Parkinson'sdisease mouse model
    • Jeon S, Kim YJ, Kim ST, et al. Proteomic analysis of the neuroprotective mechanisms of acupuncture treatment in a Parkinson'sdisease mouse model. Proteomics 2008; 8: 4822-32.
    • (2008) Proteomics , vol.8 , pp. 4822-4832
    • Jeon, S.1    Kim, Y.J.2    Kim, S.T.3
  • 73
    • 67650376532 scopus 로고    scopus 로고
    • A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications
    • Ji B, La Y, Gao L, et al. A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications. J Proteome Res 2009; 8(7):3633-41.
    • (2009) J Proteome Res , vol.8 , Issue.7 , pp. 3633-3641
    • Ji, B.1    La, Y.2    Gao, L.3
  • 74
    • 0142244688 scopus 로고    scopus 로고
    • Schizophrenia
    • Freedman R. Schizophrenia. N Engl J Med 2003; 349(18): 1738-49.
    • (2003) N Engl J Med , vol.349 , Issue.18 , pp. 1738-1749
    • Freedman, R.1
  • 75
    • 33750842955 scopus 로고    scopus 로고
    • Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats
    • Lin ED, Lee NJ, Slack K, et al. Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats. Neuropharmacology 2006; 51: 1129-36.
    • (2006) Neuropharmacology , vol.51 , pp. 1129-1136
    • Lin, E.D.1    Lee, N.J.2    Slack, K.3
  • 76
    • 60249083428 scopus 로고    scopus 로고
    • Dose trends for secondgeneration antipsychotic treatment of schizophrenia and bipolardisorder
    • Citrome L, Reist C, Palmer L, et al. Dose trends for secondgeneration antipsychotic treatment of schizophrenia and bipolardisorder. Schiz Res 2009; 108: 238-44.
    • (2009) Schiz Res , vol.108 , pp. 238-244
    • Citrome, L.1    Reist, C.2    Palmer, L.3
  • 77
    • 57749178176 scopus 로고    scopus 로고
    • Effect of risperidone and olanzapine on reproductive hormones, psychopathology and sexual functioning in male patients with schizophrenia
    • Konarzewska B, Wolłczyński S, Szulc A, et al. Effect of risperidone and olanzapine on reproductive hormones, psychopathology and sexual functioning in male patients with schizophrenia. Psychoneuroendocrinology 2009; 34: 129-39.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 129-139
    • Konarzewska, B.1    Wolłczyński, S.2    Szulc, A.3
  • 78
    • 69349096791 scopus 로고    scopus 로고
    • Effects of typical(haloperidol) and atypical (risperidone) antipsychotic agents onprotein expression in rat neural stem cells
    • Kashem MA, Ummehany R, Ukai W, et al. Effects of typical(haloperidol) and atypical (risperidone) antipsychotic agents onprotein expression in rat neural stem cells. Neurochem Int 2009;55: 558-65.
    • (2009) Neurochem Int , vol.55 , pp. 558-565
    • Kashem, M.A.1    Ummehany, R.2    Ukai, W.3
  • 79
    • 70349236863 scopus 로고    scopus 로고
    • Differential expression profiling of the synaptosome proteome in a rat model of antipsychotic resistance
    • Ji B, Zhang Z, Zhang M, et al. Differential expression profiling of the synaptosome proteome in a rat model of antipsychotic resistance. Brain Res 2009; 1295: 170-8.
    • (2009) Brain Res , vol.1295 , pp. 170-178
    • Ji, B.1    Zhang, Z.2    Zhang, M.3
  • 80
    • 1642352614 scopus 로고    scopus 로고
    • Mitochondrial complex I subunitsexpression is altered in schizophrenia: A postmortem study
    • Karry R, Klein E, Shachar DB. Mitochondrial complex I subunitsexpression is altered in schizophrenia: a postmortem study. BiolPsychiatry 2004; 55: 676-84.
    • (2004) BiolPsychiatry , vol.55 , pp. 676-684
    • Karry, R.1    Klein, E.2    Shachar, D.B.3
  • 81
    • 0024247522 scopus 로고
    • The current status of the dopamine hypothesis ofschizophrenia
    • Carlsson A. The current status of the dopamine hypothesis ofschizophrenia. Neuropsychopharmacology 1988; 1: 179-86.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 179-186
    • Carlsson, A.1
  • 82
    • 2342582130 scopus 로고    scopus 로고
    • NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia
    • Coyle JT, Tsai G. NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia. Int Rev Neurobiol 2004; 59: 491-515
    • (2004) Int Rev Neurobiol , vol.59 , pp. 491-515
    • Coyle, J.T.1    Tsai, G.2
  • 83
    • 1242329383 scopus 로고    scopus 로고
    • Schizophrenia: From dopamineto glutamate and back
    • Carlsson ML, Carlsson A, Nilsson M. Schizophrenia: from dopamineto glutamate and back. Curr Med Chem 2004; 11: 267-77.
    • (2004) Curr Med Chem , vol.11 , pp. 267-277
    • Carlsson, M.L.1    Carlsson, A.2    Nilsson, M.3
  • 84
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney JW, Farber NB. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry 1995; 52: 998-1007.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 85
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 1991; 148: 1301-8.
    • (1991) Am J Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 86
    • 34347345955 scopus 로고    scopus 로고
    • Proteome analysis after coadministration of clozapine or haloperidol to MK-801-treated rats
    • Paulson L, Martin P, Ljung E, et al. Proteome analysis after coadministration of clozapine or haloperidol to MK-801-treated rats. J Neural Transm 2007; 114: 885-91.
    • (2007) J Neural Transm , vol.114 , pp. 885-891
    • Paulson, L.1    Martin, P.2    Ljung, E.3
  • 87
    • 0027048247 scopus 로고
    • MK-801 induced stereotypes in rats are decreased by haloperidol and increased by diazepam
    • Behrens S, Gattaz WF. MK-801 induced stereotypes in rats are decreased by haloperidol and increased by diazepam. J Neural Transm Gen Sect 1992; 90: 219-24.
    • (1992) J Neural Transm Gen Sect , vol.90 , pp. 219-224
    • Behrens, S.1    Gattaz, W.F.2
  • 88
    • 0026779303 scopus 로고
    • Typical and atypical neuroleptics antagonize MK-801- induced locomotion and stereotypy in rats
    • Hoffman DC. Typical and atypical neuroleptics antagonize MK-801- induced locomotion and stereotypy in rats. J Neural Transm Gen Sect 1992; 89: 1-10.
    • (1992) J Neural Transm Gen Sect , vol.89 , pp. 1-10
    • Hoffman, D.C.1
  • 89
    • 33750695928 scopus 로고    scopus 로고
    • Comparative proteome analysis revealed up regulation of transthyretin in rat brain under chronic clozapine treatment
    • Chen ML, Chen DH. Comparative proteome analysis revealed up regulation of transthyretin in rat brain under chronic clozapine treatment. J Psychiat Res 2007; 41: 63-8.
    • (2007) J Psychiat Res , vol.41 , pp. 63-68
    • Chen, M.L.1    Chen, D.H.2
  • 90
    • 0036910522 scopus 로고    scopus 로고
    • Hepatic synthesis, maturation and complex formation between retinal-binding protein and transthyretin
    • Gaetani S, Bellovino D, Apreda M, et al. Hepatic synthesis, maturation and complex formation between retinal-binding protein and transthyretin. Clin Chem Lab Med 2002; 40: 1211-20.
    • (2002) Clin Chem Lab Med , vol.40 , pp. 1211-1220
    • Gaetani, S.1    Bellovino, D.2    Apreda, M.3
  • 91
    • 0036910380 scopus 로고    scopus 로고
    • Transthyretin as a thyroid hormone carrier: Function revisited
    • Palha JA. Transthyretin as a thyroid hormone carrier: function revisited. Clin Chem Lab Med 2002; 40: 1292-300.
    • (2002) Clin Chem Lab Med , vol.40 , pp. 1292-1300
    • Palha, J.A.1
  • 92
    • 0032560480 scopus 로고    scopus 로고
    • Three independent lines of evidence suggest retinoids as causal to schizophrenia
    • Goodman AB. Three independent lines of evidence suggest retinoids as causal to schizophrenia. Proc Natl Acad Sci USA 1998;95: 7240-4.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7240-7244
    • Goodman, A.B.1
  • 93
    • 51449105218 scopus 로고
    • Paliperidoneas a mood stabilizer: A pre-frontal cortex synaptoneurosomalproteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression
    • Corena-McLeod MP, Oliveros A, Charlesworth C, et al. Paliperidoneas a mood stabilizer: A pre-frontal cortex synaptoneurosomalproteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression. Brain Res2008; 1233: 8-19.
    • (1233) Brain Res2008 , pp. 8-19
    • Corena-McLeod, M.P.1    Oliveros, A.2    Charlesworth, C.3
  • 94
    • 0034711425 scopus 로고    scopus 로고
    • Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
    • Richelson E, Souder T. Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci 2000; 68: 29-39.
    • (2000) Life Sci , vol.68 , pp. 29-39
    • Richelson, E.1    Souder, T.2
  • 95
    • 34548024621 scopus 로고    scopus 로고
    • Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of ratseroton in and norepinephrine neurons
    • Dremencov E, El Mansari M, Blier P. Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of ratseroton in and norepinephrine neurons. Psychopharmacology 2007;194: 63-72.
    • (2007) Psychopharmacology , vol.194 , pp. 63-72
    • Dremencov, E.1    El Mansari, M.2    Blier, P.3
  • 96
    • 0345895413 scopus 로고    scopus 로고
    • Asymmetry, stem cells and the emergence of function
    • McKay R. Asymmetry, stem cells and the emergence of function. Clin Neurosci Res 2001; 1: 183-6.
    • (2001) Clin Neurosci Res , vol.1 , pp. 183-186
    • McKay, R.1
  • 97
    • 0036645379 scopus 로고    scopus 로고
    • Atypical neuroleptics stimulate neurogenesis in adult rat brain
    • Wakade CG, Mahadik SP, Waller JL, et al. Atypical neuroleptics stimulate neurogenesis in adult rat brain. J Neurosci Res 2002; 69:72-9.
    • (2002) J Neurosci Res , vol.69 , pp. 72-79
    • Wakade, C.G.1    Mahadik, S.P.2    Waller, J.L.3
  • 98
    • 2642545991 scopus 로고    scopus 로고
    • Neurotoxic potential of haloperidol in comparison with risperidone: Implication of Akt-mediatedsignal changes by haloperidol
    • Ukai W, Ozawa H, Tateno N, et al. Neurotoxic potential of haloperidol in comparison with risperidone: implication of Akt-mediatedsignal changes by haloperidol. J Neural Transm 2004; 111: 667-81.
    • (2004) J Neural Transm , vol.111 , pp. 667-681
    • Ukai, W.1    Ozawa, H.2    Tateno, N.3
  • 99
    • 34548165477 scopus 로고    scopus 로고
    • Olanzapine potentiatesneuronal survival and neural stem cell differentiation: Regulation of endoplasmic reticulum stress response proteins
    • Kurosawa S, Hashimoto E, Ukai W, et al. Olanzapine potentiatesneuronal survival and neural stem cell differentiation: regulation of endoplasmic reticulum stress response proteins. J Neural Transm 2007; 114: 1121-8.
    • (2007) J Neural Transm , vol.114 , pp. 1121-1128
    • Kurosawa, S.1    Hashimoto, E.2    Ukai, W.3
  • 100
    • 0032712968 scopus 로고    scopus 로고
    • SPARC, a matrixcellular glyprotein with importantbiological functions
    • Yan Q, Sage EH. SPARC, a matrixcellular glyprotein with importantbiological functions. J Histochem Cytochem 1999; 47: 1495-505.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1495-1505
    • Yan, Q.1    Sage, E.H.2
  • 101
    • 0032531268 scopus 로고    scopus 로고
    • SPARC inhibits endothelial cell adhesionbut not proliferation through a tyrosine phosphorylation-dependentpathway
    • Motamed K, Sage EH. SPARC inhibits endothelial cell adhesionbut not proliferation through a tyrosine phosphorylation-dependentpathway. J Cell Biochem 1998; 70: 543-5.
    • (1998) J Cell Biochem , vol.70 , pp. 543-545
    • Motamed, K.1    Sage, E.H.2
  • 102
    • 33748688816 scopus 로고    scopus 로고
    • Effects of chronic risperidonetreatment on the striatal proteinprofiles in rats
    • O'Brien E, Dedova I, Duffy L, et al. Effects of chronic risperidonetreatment on the striatal proteinprofiles in rats. Brain Res 2006;1113: 24-32.
    • (2006) Brain Res , vol.1113 , pp. 24-32
    • O'Brien, E.1    Dedova, I.2    Duffy, L.3
  • 103
    • 0037870490 scopus 로고    scopus 로고
    • Schizophrenia: From phenomenology to neurobiology
    • Wong AH, Van Tol HH. Schizophrenia: from phenomenology to neurobiology. Neurosci. Biobehav Rev 2003; 27(3): 269-306.
    • (2003) Neurosci. Biobehav Rev , vol.27 , Issue.3 , pp. 269-306
    • Wong, A.H.1    van Tol, H.H.2
  • 104
    • 33646818313 scopus 로고    scopus 로고
    • Mechanismof action of atypicalantipsychotic drugs and the neurobiology ofschizophrenia
    • Horacek J, Bubenikova-Valesova V, Kopecek M, et al. Mechanismof action of atypicalantipsychotic drugs and the neurobiology ofschizophrenia. CNS Drugs 2006; 20(5): 389-409.
    • (2006) CNS Drugs , vol.20 , Issue.5 , pp. 389-409
    • Horacek, J.1    Bubenikova-Valesova, V.2    Kopecek, M.3
  • 105
    • 33745427099 scopus 로고    scopus 로고
    • Olanzapine differentially affects5-HT2Aand2C receptor mRNA expression in the rat brain
    • Huang XF, Han M, Huang X, et al. Olanzapine differentially affects5-HT2Aand2C receptor mRNA expression in the rat brain. Behav Brain Res 2006; 171(2): 355-62.
    • (2006) Behav Brain Res , vol.171 , Issue.2 , pp. 355-362
    • Huang, X.F.1    Han, M.2    Huang, X.3
  • 106
    • 32644463170 scopus 로고    scopus 로고
    • Treatment with olanzapineincreases cell proliferation in the subventricular zone and prefrontalcortex
    • Green W, Patil P, Marsden CA, et al. Treatment with olanzapineincreases cell proliferation in the subventricular zone and prefrontalcortex. Brain Res 2006; 1070(1): 242-5.
    • (2006) Brain Res , vol.1070 , Issue.1 , pp. 242-245
    • Green, W.1    Patil, P.2    Marsden, C.A.3
  • 107
    • 33746920344 scopus 로고    scopus 로고
    • Differential effects of haloperidol and olanzapineon the expression of erythropoietin and its receptor in rathippocampus and striatum
    • Pillai A, Mahadik SP. Differential effects of haloperidol and olanzapineon the expression of erythropoietin and its receptor in rathippocampus and striatum. J Neurochem 2006; 98(5): 1411-22.
    • (2006) J Neurochem , vol.98 , Issue.5 , pp. 1411-1422
    • Pillai, A.1    Mahadik, S.P.2
  • 108
    • 2442691413 scopus 로고    scopus 로고
    • Effects of chronichaloperidol and clozapine treatment on neurogenesis in the adult rathippocampus
    • Halim ND, Weickert CS, McClintock BW, et al. Effects of chronichaloperidol and clozapine treatment on neurogenesis in the adult rathippocampus. Neuropsychopharmacology 2004; 29(6): 1063-9.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.6 , pp. 1063-1069
    • Halim, N.D.1    Weickert, C.S.2    McClintock, B.W.3
  • 109
    • 0037414404 scopus 로고    scopus 로고
    • Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism
    • Dwyer DS, Lu XH, Bradley RJ. Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism. Brain Res 2003; 971(1): 31-9.
    • (2003) Brain Res , vol.971 , Issue.1 , pp. 31-39
    • Dwyer, D.S.1    Lu, X.H.2    Bradley, R.J.3
  • 110
    • 67650354396 scopus 로고    scopus 로고
    • Antipsychotic Treatment Alters Protein Expression Associated with Presynaptic Function and Nervous System Development in Rat Frontal Cortex
    • Ma D, Chan MK, Lockstone HE, et al. Antipsychotic Treatment Alters Protein Expression Associated with Presynaptic Function and Nervous System Development in Rat Frontal Cortex. J ProteomeRes 2009; 8: 3284-97.
    • (2009) J ProteomeRes , vol.8 , pp. 3284-3297
    • Ma, D.1    Chan, M.K.2    Lockstone, H.E.3
  • 111
    • 24344433989 scopus 로고    scopus 로고
    • Association between the neuregulin1 gene and schizophrenia: A systematic review
    • Tosato S, Dazzan P, Collier D. Association between the neuregulin1 gene and schizophrenia: a systematic review. Schizophr Bull 2005; 31(3): 613-7.
    • (2005) Schizophr Bull , vol.31 , Issue.3 , pp. 613-617
    • Tosato, S.1    Dazzan, P.2    Collier, D.3
  • 112
    • 23244446234 scopus 로고    scopus 로고
    • Changes in calcineurinexpression induced in the rat brain by the administration of antipsychotics
    • Rushlow WJ, Seah YH, Belliveau DJ, et al. Changes in calcineurinexpression induced in the rat brain by the administration of antipsychotics. J Neurochem 2005; 94(3): 587-96.
    • (2005) J Neurochem , vol.94 , Issue.3 , pp. 587-596
    • Rushlow, W.J.1    Seah, Y.H.2    Belliveau, D.J.3
  • 113
    • 33947519123 scopus 로고    scopus 로고
    • Molecular profiling of antipsychotic drug function:Convergent mechanisms in the pathology and treatment of psychiatric disorders
    • Thomas EA. Molecular profiling of antipsychotic drug function:convergent mechanisms in the pathology and treatment of psychiatric disorders. Mol Neurobiol 2006; 34(2): 109-28.
    • (2006) Mol Neurobiol , vol.34 , Issue.2 , pp. 109-128
    • Thomas, E.A.1
  • 114
    • 34848897470 scopus 로고    scopus 로고
    • Association of synapsin 2 with schizophrenia in families of Northern Europeanancestry
    • Saviouk V, Moreau MP, Tereshchenko IV, et al. Association of synapsin 2 with schizophrenia in families of Northern Europeanancestry. Schizophr Res 2007; 96(1-3): 100-11.
    • (2007) Schizophr Res , vol.96 , Issue.1-3 , pp. 100-111
    • Saviouk, V.1    Moreau, M.P.2    Tereshchenko, I.V.3
  • 115
    • 38349025623 scopus 로고    scopus 로고
    • Deficits in social behavior and sensorimotorgating in mice lacking phospholipase C beta1
    • Koh HY, Kim D, Lee J, et al. Deficits in social behavior and sensorimotorgating in mice lacking phospholipase C beta1. GenesBrain Behav 2008; 7(1): 120-8.
    • (2008) GenesBrain Behav , vol.7 , Issue.1 , pp. 120-128
    • Koh, H.Y.1    Kim, D.2    Lee, J.3
  • 116
    • 39749154052 scopus 로고    scopus 로고
    • Differential regulation of the NMDA receptor by acute and sub-chronic phencyclidine administration inthe developing rat
    • Anastasio NC, Johnson KM. Differential regulation of the NMDA receptor by acute and sub-chronic phencyclidine administration inthe developing rat. J Neurochem 2008; 104(5): 1210-8.
    • (2008) J Neurochem , vol.104 , Issue.5 , pp. 1210-1218
    • Anastasio, N.C.1    Johnson, K.M.2
  • 117
    • 34848926265 scopus 로고    scopus 로고
    • Haloperidol induces the nucleartranslocation of phosphatidylinositol 3'-kinase to disrupt Aktphosphorylation in PC12 cells
    • Dai Y, Wei Z, Sephton CF, et al. Haloperidol induces the nucleartranslocation of phosphatidylinositol 3'-kinase to disrupt Aktphosphorylation in PC12 cells. J Psychiatry Neurosci 2007; 32(5):323-30.
    • (2007) J Psychiatry Neurosci , vol.32 , Issue.5 , pp. 323-330
    • Dai, Y.1    Wei, Z.2    Sephton, C.F.3
  • 118
    • 34250777818 scopus 로고    scopus 로고
    • Olanzapine increasesRGS7 protein expression via stimulation of the Janus tyrosinekinase-signal transducer and activator of transcription signalingcascade
    • Singh RK, Shi J, Zemaitaitis BW, et al. Olanzapine increasesRGS7 protein expression via stimulation of the Janus tyrosinekinase-signal transducer and activator of transcription signalingcascade. J Pharmacol Exp Ther 2007; 322(1): 133-40.
    • (2007) J Pharmacol Exp Ther , vol.322 , Issue.1 , pp. 133-140
    • Singh, R.K.1    Shi, J.2    Zemaitaitis, B.W.3
  • 119
    • 70350464937 scopus 로고    scopus 로고
    • Proteomic analysis of lithiuminducedgene expression in the rat hypothalamus
    • Lee JY, Lee JH, Moon YW, et al. Proteomic analysis of lithiuminducedgene expression in the rat hypothalamus. Int J Neurosci 2009; 119(9): 1267-81.
    • (2009) Int J Neurosci , vol.119 , Issue.9 , pp. 1267-1281
    • Lee, J.Y.1    Lee, J.H.2    Moon, Y.W.3
  • 120
    • 34548329120 scopus 로고    scopus 로고
    • Meta-analysis of 12genomic studies in bipolar disorder
    • Elashoff M, Higgs BW, Yolken RH, et al. Meta-analysis of 12genomic studies in bipolar disorder. J Mol Neurosci 2007; 31: 221-43.
    • (2007) J Mol Neurosci , vol.31 , pp. 221-243
    • Elashoff, M.1    Higgs, B.W.2    Yolken, R.H.3
  • 121
    • 34447331043 scopus 로고    scopus 로고
    • A microarray gene expressionstudy of the molecular pharmacology of lithium carbonate onmouse brain mRNA to understand the neurobiology of mood stabilizationand treatment of bipolar affective disorder
    • McQuillin A, Rizig M, Gurling HM. A microarray gene expressionstudy of the molecular pharmacology of lithium carbonate onmouse brain mRNA to understand the neurobiology of mood stabilizationand treatment of bipolar affective disorder. PharmacogenetGenomics 2007; 17: 605-17.
    • (2007) PharmacogenetGenomics , vol.17 , pp. 605-617
    • McQuillin, A.1    Rizig, M.2    Gurling, H.M.3
  • 122
    • 0037631324 scopus 로고    scopus 로고
    • 14-3-3 connectsglycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex
    • Agarwal-Mawal A, Qureshi HY, Cafferty PW, et al. 14-3-3 connectsglycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex. J Biol Chem 2003;278: 12722-8.
    • (2003) J Biol Chem , vol.278 , pp. 12722-12728
    • Agarwal-Mawal, A.1    Qureshi, H.Y.2    Cafferty, P.W.3
  • 123
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • F.E. Bloom and D.J. Kupfer, Editors, The Fourth Generation of Progress Raven Press New YorkUSA
    • Maes M, Meltzer HY. The serotonin hypothesis of major depression. In: F.E. Bloom and D.J. Kupfer, Editors, Psychopharmacology. The Fourth Generation of Progress Raven Press New YorkUSA 1995; 933-44.
    • (1995) Psychopharmacology , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 124
    • 33846599777 scopus 로고    scopus 로고
    • Proteomic analysis of rat cortical neurons after fluoxetine treatment
    • Daniela C, Silvia M, Hubert A, et al. Proteomic analysis of rat cortical neurons after fluoxetine treatment. Brain Res 2007;1135(2): 41-51.
    • (2007) Brain Res , vol.1135 , Issue.2 , pp. 41-51
    • Daniela, C.1    Silvia, M.2    Hubert, A.3
  • 125
    • 0026029774 scopus 로고
    • Fluoxetine, a selectiveinhibitor of serotonin uptake
    • Fuller RW, Wong DT, Robertson DW. Fluoxetine, a selectiveinhibitor of serotonin uptake, Med Res Rev 1991; 11: 17-34.
    • (1991) Med Res Rev , vol.11 , pp. 17-34
    • Fuller, R.W.1    Wong, D.T.2    Robertson, D.W.3
  • 126
    • 0742287855 scopus 로고    scopus 로고
    • Proteomic Analysis of ProteinChanges Developing in Rat Hippocampus After Chronic Antidepressant Treatment: Implications for Depressive Disorders and FutureTherapies
    • Khawaja X, Xu J, Liang JJ, et al. Proteomic Analysis of ProteinChanges Developing in Rat Hippocampus After Chronic Antidepressant Treatment: Implications for Depressive Disorders and FutureTherapies. J Neurosci Res 2004; 75: 451-60.
    • (2004) J Neurosci Res , vol.75 , pp. 451-460
    • Khawaja, X.1    Xu, J.2    Liang, J.J.3
  • 127
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressanttreatment increases neurogenesis in adult rat hippocampus
    • Malberg JE, Eisch AJ, Nestler EJ, et al. Chronic antidepressanttreatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000; 20: 9104-10.
    • (2000) J Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3
  • 128
    • 33748616526 scopus 로고    scopus 로고
    • Proteomic analysis of rat hippocampusand frontal cortex after chronic treatment with fluoxetineor putative novel antidepressants: CRF1 and NK1 receptor antagonists
    • Lucia C, Miriam V, Chiara P, et al. Proteomic analysis of rat hippocampusand frontal cortex after chronic treatment with fluoxetineor putative novel antidepressants: CRF1 and NK1 receptor antagonists. Eur Neuropsychopharmacol 2006; 16: 521-37.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 521-537
    • Lucia, C.1    Miriam, V.2    Chiara, P.3
  • 129
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinitycorticotropinreleasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated
    • Zobel AW, Nickel T, Kqnzel HE, et al. Effects of the high-affinitycorticotropinreleasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J Psychiatr Res 2000; 34: 171-81.
    • (2000) J Psychiatr Res , vol.34 , pp. 171-181
    • Zobel, A.W.1    Nickel, T.2    Kqnzel, H.E.3
  • 130
    • 2642547366 scopus 로고    scopus 로고
    • Antidepressant properties of substance P antagonists:Relationship to monoaminergic mechanisms
    • Adell A. Antidepressant properties of substance P antagonists:relationship to monoaminergic mechanisms? Curr Drug Targets CNS Neurol Disord 2004; 3: 113-21.491-515.
    • (2004) Curr Drug Targets CNS Neurol Disord , vol.3
    • Adell, A.1
  • 131
    • 45349107889 scopus 로고    scopus 로고
    • Evidence-basedguidelines for treating depressive disorders with antidepressants: Arevision of the 2000 British Association for Psychopharmacologyguidelines
    • Anderson IM, Ferrier IN, Baldwin RC, et al. Evidence-basedguidelines for treating depressive disorders with antidepressants: arevision of the 2000 British Association for Psychopharmacologyguidelines. J Psychopharmacol 2008; 22: 343-96.
    • (2008) J Psychopharmacol , vol.22 , pp. 343-396
    • Anderson, I.M.1    Ferrier, I.N.2    Baldwin, R.C.3
  • 132
    • 56349103640 scopus 로고    scopus 로고
    • Why antidepressants are not antidepressants: STEPBD, STARD, and the return of neurotic depression
    • Ghaemi SN. Why antidepressants are not antidepressants: STEPBD, STARD, and the return of neurotic depression. Bipolar Disord 2008; 10(8): 957-68.
    • (2008) Bipolar Disord , vol.10 , Issue.8 , pp. 957-968
    • Ghaemi, S.N.1
  • 133
    • 33646687927 scopus 로고    scopus 로고
    • Why do we need new and better antidepressants?
    • Montgomery SA. Why do we need new and better antidepressants? Int Clin Psychopharmacol 2006; 21: S1-S10.
    • (2006) Int Clin Psychopharmacol , vol.21
    • Montgomery, S.A.1
  • 134
    • 79958787546 scopus 로고    scopus 로고
    • Escitalopram modulatesneuron-remodelling proteins in a rat gene-environment interactionmodel of depression as revealed by proteomics. Part I: Geneticbackground
    • Piubelli1 C, Vighini M, Mathé AA, et al. Escitalopram modulatesneuron-remodelling proteins in a rat gene-environment interactionmodel of depression as revealed by proteomics. Part I: geneticbackground. Int J Neuropsychopharmacol 2010; 8: 1-38.
    • (2010) Int J Neuropsychopharmacol , vol.8 , pp. 1-38
    • Piubelli, C.1    Vighini, M.2    Mathé, A.A.3
  • 135
    • 0036468982 scopus 로고    scopus 로고
    • The oncoprotein 18/stathmin family of microtubuledestabilizers
    • Cassimeris L. The oncoprotein 18/stathmin family of microtubuledestabilizers. Curr Opin Cell Biol 2002; 14:18-24.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 18-24
    • Cassimeris, L.1
  • 136
    • 73649100292 scopus 로고    scopus 로고
    • Role of the PACAPPAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophreniaand bipolar disorder: Novel treatment mechanisms?
    • Katayama T, Hattori T, Yamada K, et al. Role of the PACAPPAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophreniaand bipolar disorder: novel treatment mechanisms? Pharmacogenomics 2009; 10: 1967-78.
    • (2009) Pharmacogenomics , vol.10 , pp. 1967-1978
    • Katayama, T.1    Hattori, T.2    Yamada, K.3
  • 137
    • 33748616526 scopus 로고    scopus 로고
    • Proteomic analysis of rathippocampus and frontal cortex after chronic treatment withfluoxetine or putative novel antidepressants: CRF1 and NK1 receptorantagonists
    • Carboni L, Vighini M, Piubelli C, et al. Proteomic analysis of rathippocampus and frontal cortex after chronic treatment withfluoxetine or putative novel antidepressants: CRF1 and NK1 receptorantagonists. Eur Neuropsychopharmacol 2006; 16(7): 521-37.
    • (2006) Eur Neuropsychopharmacol , vol.16 , Issue.7 , pp. 521-537
    • Carboni, L.1    Vighini, M.2    Piubelli, C.3
  • 138
    • 44749088966 scopus 로고    scopus 로고
    • Proteomic analysis ofphospholipidosis in citalopram treated U937 cells - support for thecholesterol biosynthesis hypothesis
    • Hutchinson TH, Mahshid Y, Jonsson R, et al. Proteomic analysis ofphospholipidosis in citalopram treated U937 cells - support for thecholesterol biosynthesis hypothesis. Toxicol In Vitro 2008; 22:1198-204.
    • (2008) Toxicol In Vitro , vol.22 , pp. 1198-1204
    • Hutchinson, T.H.1    Mahshid, Y.2    Jonsson, R.3
  • 139
    • 38849096508 scopus 로고    scopus 로고
    • Proteomic analysis ofembryonic stem cell-derived neural cells exposed to the antidepressantparoxetine
    • McHugh PC, Rogers GR, Loudon B, et al. Proteomic analysis ofembryonic stem cell-derived neural cells exposed to the antidepressantparoxetine. J Neurosci Res 2008; 86: 306-16.
    • (2008) J Neurosci Res , vol.86 , pp. 306-316
    • McHugh, P.C.1    Rogers, G.R.2    Loudon, B.3
  • 140
    • 33845369874 scopus 로고    scopus 로고
    • Expression analysis ofactin-related genes as an underlying mechanism for mood disorders
    • Nakatani N, Ohnishi T, Iwamoto K, et al. Expression analysis ofactin-related genes as an underlying mechanism for mood disorders. Biochem Biophys Res Commun 2007; 352: 780-6.
    • (2007) Biochem Biophys Res Commun , vol.352 , pp. 780-786
    • Nakatani, N.1    Ohnishi, T.2    Iwamoto, K.3
  • 141
    • 0141888372 scopus 로고    scopus 로고
    • The distribution and morphology of prefrontalcortex pyramidal neurons identified using anti-neurofilamentantibodies SMI32, N200 and FNP7. Normative data and a comparisonin subjects with schizophrenia, bipolar disorder or major depression
    • Law AJ, Harrison PJ. The distribution and morphology of prefrontalcortex pyramidal neurons identified using anti-neurofilamentantibodies SMI32, N200 and FNP7. Normative data and a comparisonin subjects with schizophrenia, bipolar disorder or major depression. J Psychiatr Res 2003; 37: 487-99.
    • (2003) J Psychiatr Res , vol.37 , pp. 487-499
    • Law, A.J.1    Harrison, P.J.2
  • 142
    • 20444404230 scopus 로고    scopus 로고
    • Unchanged packingdensity but altered size of neurofilament immunoreactive neuronsin the prefrontal cortex in schizophrenia and major depression
    • Miguel-Hidalgo JJ, Dubey P, Shao Q, et al. Unchanged packingdensity but altered size of neurofilament immunoreactive neuronsin the prefrontal cortex in schizophrenia and major depression. Schizophr Res 2005; 76: 159-71.
    • (2005) Schizophr Res , vol.76 , pp. 159-171
    • Miguel-Hidalgo, J.J.1    Dubey, P.2    Shao, Q.3
  • 143
    • 34548143369 scopus 로고    scopus 로고
    • Cytoskeleton of hippocampalneurons as a target for valproic acid in an experimentalmodel of depression
    • Ferrero AJ, Cereseto M, Sifonios LL, et al. Cytoskeleton of hippocampalneurons as a target for valproic acid in an experimentalmodel of depression. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31: 1419-28.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 1419-1428
    • Ferrero, A.J.1    Cereseto, M.2    Sifonios, L.L.3
  • 144
    • 10744222370 scopus 로고    scopus 로고
    • Mechanisms of action of the antidepressants fluoxetine and the substance P antagonistL-000760735 are associated with altered neurofilamentsand synaptic remodeling
    • Guest PC, Knowles MR, Molon-Noblot S, et al. Mechanisms of action of the antidepressants fluoxetine and the substance P antagonistL-000760735 are associated with altered neurofilamentsand synaptic remodeling. Brain Res 2004; 1002: 1-10.
    • (2004) Brain Res , vol.1002 , pp. 1-10
    • Guest, P.C.1    Knowles, M.R.2    Molon-Noblot, S.3
  • 145
    • 0033987639 scopus 로고    scopus 로고
    • Alterations in heavy andlight neurofilament proteins in hippocampus following chronicECS administration
    • Vaidya VA, Terwilliger RZ, Duman RS. Alterations in heavy andlight neurofilament proteins in hippocampus following chronicECS administration. Synapse 2000; 35: 137-43.
    • (2000) Synapse , vol.35 , pp. 137-143
    • Vaidya, V.A.1    Terwilliger, R.Z.2    Duman, R.S.3
  • 146
    • 26844446528 scopus 로고    scopus 로고
    • Neuronal plasticity, stressand depression: Involvement of the cytoskeletal microtubular system?
    • Bianchi M, Hagan JJ, Heidbreder CA. Neuronal plasticity, stressand depression: involvement of the cytoskeletal microtubular system? Curr Drug Targets CNS Neurol Disord 2005; 4: 597-611.
    • (2005) Curr Drug Targets CNS Neurol Disord , vol.4 , pp. 597-611
    • Bianchi, M.1    Hagan, J.J.2    Heidbreder, C.A.3
  • 147
    • 0033041132 scopus 로고    scopus 로고
    • Alterations of tubulin functioncaused by chronic antidepressant treatment in rat brain
    • Kamada H, Saito T, Hatta S, et al. Alterations of tubulin functioncaused by chronic antidepressant treatment in rat brain. Cell MolNeurobiol 1999; 19: 109-17.
    • (1999) Cell MolNeurobiol , vol.19 , pp. 109-117
    • Kamada, H.1    Saito, T.2    Hatta, S.3
  • 148
    • 70349782392 scopus 로고    scopus 로고
    • Cytoskeletal alterations in rathippocampus following chronic unpredictable mild stress and reexposureto acute and chronic unpredictable mild stress
    • Yang C, Wang G, Wang H, et al. Cytoskeletal alterations in rathippocampus following chronic unpredictable mild stress and reexposureto acute and chronic unpredictable mild stress. BehavioralBrain Res 2009; 205: 518-24.
    • (2009) BehavioralBrain Res , vol.205 , pp. 518-524
    • Yang, C.1    Wang, G.2    Wang, H.3
  • 149
    • 0033974460 scopus 로고    scopus 로고
    • Increased temporal cortexER stress proteins in depressed subjects who died by suicide
    • Bown C, Wang JF, MacQueen G, et al. Increased temporal cortexER stress proteins in depressed subjects who died by suicide. Neuropsychopharmacology 2000; 22: 327-32.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 327-332
    • Bown, C.1    Wang, J.F.2    Macqueen, G.3
  • 150
    • 0034307061 scopus 로고    scopus 로고
    • Chronic valproate treatment increasesexpression of endoplasmic reticulum stress proteins in therat cerebral cortex and hippocampus
    • Chen B, Wang JF, Young LT. Chronic valproate treatment increasesexpression of endoplasmic reticulum stress proteins in therat cerebral cortex and hippocampus. Biol Psychiatry 2000; 48:658-64.
    • (2000) Biol Psychiatry , vol.48 , pp. 658-664
    • Chen, B.1    Wang, J.F.2    Young, L.T.3
  • 151
    • 32044462724 scopus 로고    scopus 로고
    • Mood stabilizing drug lithium increasesexpression of endoplasmic reticulum stress proteins in primary culturedrat cerebral cortical cells
    • Shao L, Sun X, Xu L, et al. Mood stabilizing drug lithium increasesexpression of endoplasmic reticulum stress proteins in primary culturedrat cerebral cortical cells. Life Sci 2006; 78: 1317-23.
    • (2006) Life Sci , vol.78 , pp. 1317-1323
    • Shao, L.1    Sun, X.2    Xu, L.3
  • 152
    • 77951909679 scopus 로고    scopus 로고
    • Proteomic analysis to identify early molecular targetsof pregabalin in C6 glial cells
    • Park S, Lee J. Proteomic analysis to identify early molecular targetsof pregabalin in C6 glial cells. Cell Biol Int 2010; 34: 27-33.
    • (2010) Cell Biol Int , vol.34 , pp. 27-33
    • Park, S.1    Lee, J.2
  • 153
    • 78751582250 scopus 로고    scopus 로고
    • Characterization, using comparativeproteomics, of differentially expressed proteins in the hippocampusof the mesial temporal lobe of epileptic rats following treatmentwith valproate
    • Wu L, Peng J, Wei C, et al. Characterization, using comparativeproteomics, of differentially expressed proteins in the hippocampusof the mesial temporal lobe of epileptic rats following treatmentwith valproate. Amino Acids 2010; 40(1): 221-38.
    • (2010) Amino Acids , vol.40 , Issue.1 , pp. 221-238
    • Wu, L.1    Peng, J.2    Wei, C.3
  • 154
    • 0027703568 scopus 로고
    • Seizures in the developing brain
    • Moshe SL. Seizures in the developing brain. Neurology 1993; 43:S3-S7.
    • (1993) Neurology , vol.43
    • Moshe, S.L.1
  • 155
    • 0028836283 scopus 로고
    • Effects of conventional antiepilepticdrugs in a model of spontaneous recurrent seizures in rats
    • Leite JP, Cavalheiro EA. Effects of conventional antiepilepticdrugs in a model of spontaneous recurrent seizures in rats. EpilepsyRes 1995; 20(2): 93-104.
    • (1995) EpilepsyRes , vol.20 , Issue.2 , pp. 93-104
    • Leite, J.P.1    Cavalheiro, E.A.2
  • 156
    • 33846030193 scopus 로고    scopus 로고
    • Targets for antiepileptic drugs in the synapse
    • Landmark CJ. Targets for antiepileptic drugs in the synapse. MedSci Monit 2007; 13(1): RA1-RA7.
    • (2007) MedSci Monit , vol.13 , Issue.1
    • Landmark, C.J.1
  • 157
    • 39149096905 scopus 로고    scopus 로고
    • Comparative proteomics andcorrelated signaling network of rat hippocampus in the pilocarpinemodel of temporal lobe epilepsy
    • Liu XY, Yang JL, Chen LJ, et al. Comparative proteomics andcorrelated signaling network of rat hippocampus in the pilocarpinemodel of temporal lobe epilepsy. Proteomics 2008; 8(3): 582-603.
    • (2008) Proteomics , vol.8 , Issue.3 , pp. 582-603
    • Liu, X.Y.1    Yang, J.L.2    Chen, L.J.3
  • 158
    • 34248183553 scopus 로고    scopus 로고
    • Proteome changes associatedwith hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus
    • Greene ND, Bamidele A, Choy M, et al. Proteome changes associatedwith hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus. Proteomics 2007; 7(8): 1336-44.
    • (2007) Proteomics , vol.7 , Issue.8 , pp. 1336-1344
    • Greene, N.D.1    Bamidele, A.2    Choy, M.3
  • 159
    • 1242321225 scopus 로고    scopus 로고
    • Riluzole enhancesglutamate uptake in rat astrocyte cultures
    • Frizzo ME, Dall'Onder LP, Dalcin KB, et al. Riluzole enhancesglutamate uptake in rat astrocyte cultures. Cell Mol Neurobiol 2004; 24: 123-8.
    • (2004) Cell Mol Neurobiol , vol.24 , pp. 123-128
    • Frizzo, M.E.1    Dall'Onder, L.P.2    Dalcin, K.B.3
  • 160
    • 33847284421 scopus 로고    scopus 로고
    • Preliminary evidence ofriluzole efficacy in antidepressant-treated patients with residual depressivesymptoms
    • Sanacora G, Kendell SF, Levin Y, et al. Preliminary evidence ofriluzole efficacy in antidepressant-treated patients with residual depressivesymptoms. Biol Psychiatry 2007; 61: 822-5.
    • (2007) Biol Psychiatry , vol.61 , pp. 822-825
    • Sanacora, G.1    Kendell, S.F.2    Levin, Y.3
  • 161
    • 13444310754 scopus 로고    scopus 로고
    • An open-label trial of theglutamate-modulating agent riluzole in combination with lithiumfor the treatment of bipolar depression
    • Zarate Jr CA, Quiroz JA, Singh JB, et al. An open-label trial of theglutamate-modulating agent riluzole in combination with lithiumfor the treatment of bipolar depression. Biol Psychiatry 2005; 57:430-2.
    • (2005) Biol Psychiatry , vol.57 , pp. 430-432
    • Zarate Jr., C.A.1    Quiroz, J.A.2    Singh, J.B.3
  • 162
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptorsas a new approach to treat schizophrenia: A randomized phase2 clinical trial
    • Patil ST, Zhang L, Martenyi F, et al. Activation of mGlu2/3 receptorsas a new approach to treat schizophrenia: a randomized phase2 clinical trial. Nat Med 2007; 13: 1102-7.
    • (2007) Nat Med , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3
  • 163
    • 33745495131 scopus 로고    scopus 로고
    • Chronic olanzapinetreatment causes differential expression of genes in frontal cortexof rats as revealed by DNA microarray technique
    • Fatemi SH, Reutiman TJ, Folsom TD, et al. Chronic olanzapinetreatment causes differential expression of genes in frontal cortexof rats as revealed by DNA microarray technique. Neuropsychopharmacology 2006; 31: 1888-99.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1888-1899
    • Fatemi, S.H.1    Reutiman, T.J.2    Folsom, T.D.3
  • 164
    • 33845801291 scopus 로고    scopus 로고
    • Lithium treatmentprevents neurocognitive deficit resulting from cranial irradiation
    • Yazlovitskaya EM, Edwards E, Thotala D, et al. Lithium treatmentprevents neurocognitive deficit resulting from cranial irradiation. Cancer Res 2006; 66: 11179-86.
    • (2006) Cancer Res , vol.66 , pp. 11179-11186
    • Yazlovitskaya, E.M.1    Edwards, E.2    Thotala, D.3
  • 166
    • 0029794770 scopus 로고    scopus 로고
    • A requirement for local protein synthesis inneurotrophin-induced hippocampal synaptic plasticity
    • Kang H, Schuman EM. A requirement for local protein synthesis inneurotrophin-induced hippocampal synaptic plasticity. Science 1996; 273(5280): 1402-6.
    • (1996) Science , vol.273 , Issue.5280 , pp. 1402-1406
    • Kang, H.1    Schuman, E.M.2
  • 167
    • 33746391137 scopus 로고    scopus 로고
    • BDNF increasessynapse density in dendrites of developing tectal neurons in vivo
    • Sanchez AL, Matthews BJ, Meynard MM, et al. BDNF increasessynapse density in dendrites of developing tectal neurons in vivo. Development 2006; 133(13): 2477-86.
    • (2006) Development , vol.133 , Issue.13 , pp. 2477-2486
    • Sanchez, A.L.1    Matthews, B.J.2    Meynard, M.M.3
  • 168
    • 0037133172 scopus 로고    scopus 로고
    • The brain-derived neurotrophicfactor enhances synthesis of Arc in synaptoneurosomes
    • Yin Y, Edelman GM, Vanderklish PW. The brain-derived neurotrophicfactor enhances synthesis of Arc in synaptoneurosomes. Proc Natl Acad Sci USA 2002; 99(4): 2368-73.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.4 , pp. 2368-2373
    • Yin, Y.1    Edelman, G.M.2    Vanderklish, P.W.3
  • 169
    • 7744224557 scopus 로고    scopus 로고
    • Brain-derived neurotrophicfactor induces mammalian target of rapamycin-dependent localactivation of translation machinery and protein synthesis in neuronaldendrites
    • Takei N, Inamura N, Kawamura M, et al. Brain-derived neurotrophicfactor induces mammalian target of rapamycin-dependent localactivation of translation machinery and protein synthesis in neuronaldendrites. J Neurosci 2004; 24(44): 9760-9.
    • (2004) J Neurosci , vol.24 , Issue.44 , pp. 9760-9769
    • Takei, N.1    Inamura, N.2    Kawamura, M.3
  • 170
    • 7244229656 scopus 로고    scopus 로고
    • BDNF regulates the translationof a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinasedependent pathway duringneuronal development
    • Schratt GM, Nigh EA, Chen WG, et al. BDNF regulates the translationof a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinasedependent pathway duringneuronal development. J Neurosci 2004; 24(33): 7366-77.
    • (2004) J Neurosci , vol.24 , Issue.33 , pp. 7366-7377
    • Schratt, G.M.1    Nigh, E.A.2    Chen, W.G.3
  • 171
    • 19944432196 scopus 로고    scopus 로고
    • Differential transport and localtranslation of cytoskeletal, injuryresponse, and neurodegenerationprotein mRNAs in axons
    • Willis D, Li KW, Zheng JQ, et al. Differential transport and localtranslation of cytoskeletal, injuryresponse, and neurodegenerationprotein mRNAs in axons. J Neurosci 2005; 25(4): 778-91.
    • (2005) J Neurosci , vol.25 , Issue.4 , pp. 778-791
    • Willis, D.1    Li, K.W.2    Zheng, J.Q.3
  • 172
    • 33947586766 scopus 로고    scopus 로고
    • BDNF Induces WidespreadChanges in Synaptic Protein Content and Up-Regulates Componentsof the Translation Machinery: An Analysis Using High-Throughput Proteomics
    • Lujian L, Julie P, Tao X, et al. BDNF Induces WidespreadChanges in Synaptic Protein Content and Up-Regulates Componentsof the Translation Machinery: An Analysis Using High-Throughput Proteomics. J Proteome Res 2007; 6:1059-71.
    • (2007) J Proteome Res , vol.6 , pp. 1059-1071
    • Lujian, L.1    Julie, P.2    Tao, X.3
  • 173
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expressionof brain-derived neurotrophic factor and receptor tyrosine kinase Bin postmortem brain of suicide subjects
    • Dwivedi Y, Rizavi HS, Conley RR, et al. Altered gene expressionof brain-derived neurotrophic factor and receptor tyrosine kinase Bin postmortem brain of suicide subjects. Arch Gen Psychiatry 2003;60: 804-15.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3
  • 174
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels inpostmortem brains of suicide victims and the effects of antemortemdiagnosis and psychotropic drugs
    • Karege F, Vaudan G, Schwald M, et al. Neurotrophin levels inpostmortem brains of suicide victims and the effects of antemortemdiagnosis and psychotropic drugs. Brain Res Mol Brain Res 2005;136: 29-37.
    • (2005) Brain Res Mol Brain Res , vol.136 , pp. 29-37
    • Karege, F.1    Vaudan, G.2    Schwald, M.3
  • 175
    • 0142040220 scopus 로고    scopus 로고
    • Effects of electroconvulsiveseizures and antidepressant drugs on brain-derived neurotrophicfactor protein in rat brain
    • Altar CA, Whitehead RE, Chen R, et al. Effects of electroconvulsiveseizures and antidepressant drugs on brain-derived neurotrophicfactor protein in rat brain. Biol Psychiatry 2003; 54: 703-9.
    • (2003) Biol Psychiatry , vol.54 , pp. 703-709
    • Altar, C.A.1    Whitehead, R.E.2    Chen, R.3
  • 176
    • 0036676160 scopus 로고    scopus 로고
    • Riluzole enhances expressionof brain-derived neurotrophic factor with consequent proliferationof granule precursor cells in the rat hippocampus
    • Katoh-Semba R, Asano T, Ueda H, et al. Riluzole enhances expressionof brain-derived neurotrophic factor with consequent proliferationof granule precursor cells in the rat hippocampus. FASEBJ 2002; 16: 1328-30.
    • (2002) FASEBJ , vol.16 , pp. 1328-1330
    • Katoh-Semba, R.1    Asano, T.2    Ueda, H.3
  • 177
    • 0033994676 scopus 로고    scopus 로고
    • Positive modulationof AMPA receptors increases neurotrophin expression by hippocampaland cortical neurons
    • Lauterborn JC, Lynch G, Vanderklish P, et al. Positive modulationof AMPA receptors increases neurotrophin expression by hippocampaland cortical neurons. J Neurosci 2000; 20: 8-21.
    • (2000) J Neurosci , vol.20 , pp. 8-21
    • Lauterborn, J.C.1    Lynch, G.2    Vanderklish, P.3
  • 178
    • 38149024046 scopus 로고    scopus 로고
    • The differential regulationof BDNF and TrkB levels in juvenile rats after four days of escitalopramand desipramine treatment
    • Kozisek ME, Middlemas D, Bylund DB. The differential regulationof BDNF and TrkB levels in juvenile rats after four days of escitalopramand desipramine treatment. Neuropharmacology 2008; 54:251-7.
    • (2008) Neuropharmacology , vol.54 , pp. 251-257
    • Kozisek, M.E.1    Middlemas, D.2    Bylund, D.B.3
  • 179
    • 0344676390 scopus 로고    scopus 로고
    • Multiple actions ofsystemic artemin in experimental neuropathy
    • Gardell LR, Wang R, Ehrenfels C, et al. Multiple actions ofsystemic artemin in experimental neuropathy. Nat Med 2003; 9:1383-9.
    • (2003) Nat Med , vol.9 , pp. 1383-1389
    • Gardell, L.R.1    Wang, R.2    Ehrenfels, C.3
  • 180
    • 0033994238 scopus 로고    scopus 로고
    • The glial cell linederivedneurotrophic factor family receptor components are differentiallyregulated within sensory neurons after nerve injury
    • Bennett DL, Boucher TJ, Armanini MP, et al. The glial cell linederivedneurotrophic factor family receptor components are differentiallyregulated within sensory neurons after nerve injury. J Neurosci 2000; 20: 427-37.
    • (2000) J Neurosci , vol.20 , pp. 427-437
    • Bennett, D.L.1    Boucher, T.J.2    Armanini, M.P.3
  • 181
    • 0034613153 scopus 로고    scopus 로고
    • Potent analgesic effects ofGDNF in neuropathic pain states
    • Boucher TJ, Okuse K, Bennett DL, et al. Potent analgesic effects ofGDNF in neuropathic pain states. Science 2000; 290: 124-7.
    • (2000) Science , vol.290 , pp. 124-127
    • Boucher, T.J.1    Okuse, K.2    Bennett, D.L.3
  • 182
    • 0034688281 scopus 로고    scopus 로고
    • Functional regeneration ofsensory axons into the adult spinal cord
    • Ramer MS, Priestley JV, McMahon SB. Functional regeneration ofsensory axons into the adult spinal cord. Nature 2000; 403: 312-6.
    • (2000) Nature , vol.403 , pp. 312-316
    • Ramer, M.S.1    Priestley, J.V.2    McMahon, S.B.3
  • 183
    • 0034687887 scopus 로고    scopus 로고
    • Neurobiology. Finding the lost target
    • Schwab ME. Neurobiology. Finding the lost target. Nature 2000;403: 257-60.
    • (2000) Nature , vol.403 , pp. 257-260
    • Schwab, M.E.1
  • 184
    • 0032408664 scopus 로고    scopus 로고
    • Artemin, a novel memberof the GDNF ligand family, supports peripheral and central neuronsand signals through the GFRα3-RET receptor complex
    • Baloh RH, Tansey MG, Lampe PA, et al. Artemin, a novel memberof the GDNF ligand family, supports peripheral and central neuronsand signals through the GFRα3-RET receptor complex. Neuron 1998; 21: 1290-302.
    • (1998) Neuron , vol.21 , pp. 1290-1302
    • Baloh, R.H.1    Tansey, M.G.2    Lampe, P.A.3
  • 185
    • 40949106814 scopus 로고    scopus 로고
    • Artemin: Basic Science and Clinical Implication
    • Park S. Artemin: Basic Science and Clinical Implication. Rev Analg 2008; 10: 23-32.
    • (2008) Rev Analg , vol.10 , pp. 23-32
    • Park, S.1
  • 186
    • 33745885330 scopus 로고    scopus 로고
    • Transcriptional regulation of artemin is relatedto neurite outgrowth and actin polymerization in mature DRG neurons
    • Park S, Hong YW. Transcriptional regulation of artemin is relatedto neurite outgrowth and actin polymerization in mature DRG neurons. Neurosci Lett 2006; 404: 61-6.
    • (2006) Neurosci Lett , vol.404 , pp. 61-66
    • Park, S.1    Hong, Y.W.2
  • 187
    • 0035282798 scopus 로고    scopus 로고
    • Pronociceptive actions ofdynorphin maintain chronic neuropathic pain
    • Wang Z, Gardell LR, Ossipov MH, et al. Pronociceptive actions ofdynorphin maintain chronic neuropathic pain. J Neurosci 2001; 21:1779-86.
    • (2001) J Neurosci , vol.21 , pp. 1779-1786
    • Wang, Z.1    Gardell, L.R.2    Ossipov, M.H.3
  • 189
    • 0036252330 scopus 로고    scopus 로고
    • Gabapentin: Pharmacology and its use in painmanagement
    • Rose MA, Kam PC. Gabapentin: pharmacology and its use in painmanagement. Anaesthesia 2002; 57: 451-62.
    • (2002) Anaesthesia , vol.57 , pp. 451-462
    • Rose, M.A.1    Kam, P.C.2
  • 190
    • 0036932994 scopus 로고    scopus 로고
    • Time course of cognitiverecovery after propofol anaesthesia: A level of processing approach
    • N'Kaoua B, Veron AL, Lespinet VC, et al. Time course of cognitiverecovery after propofol anaesthesia: a level of processing approach. J Clin Exp Neuropsychol 2002; 6: 713-9.
    • (2002) J Clin Exp Neuropsychol , vol.6 , pp. 713-719
    • N'Kaoua, B.1    Veron, A.L.2    Lespinet, V.C.3
  • 191
    • 70349332442 scopus 로고    scopus 로고
    • Proteomic profiling of the insolublefractions in the rat hippocampus post-propofol anesthesia
    • Zhanga X, Liua Y, Fengb C, et al. Proteomic profiling of the insolublefractions in the rat hippocampus post-propofol anesthesia. Neurosci Lett 2009; 465: 165-70.
    • (2009) Neurosci Lett , vol.465 , pp. 165-170
    • Zhanga, X.1    Liua, Y.2    Fengb, C.3
  • 192
    • 6344272892 scopus 로고    scopus 로고
    • Distinct patterns oftau-dependent process formation in mammalian cell lines
    • Bruijn LI, Krishnamurthy PK, Gallo JM. Distinct patterns oftau-dependent process formation in mammalian cell lines. Neuroreport 2004; 14: 2223-6.
    • (2004) Neuroreport , vol.14 , pp. 2223-2226
    • Bruijn, L.I.1    Krishnamurthy, P.K.2    Gallo, J.M.3
  • 193
    • 0030886662 scopus 로고    scopus 로고
    • Evaluation of gabapentinand S-(+)-3-isobutylgaba in a rat model of postoperative pain
    • Field MJ, Holloman EF, McCleary S, et al. Evaluation of gabapentinand S-(+)-3-isobutylgaba in a rat model of postoperative pain. JPharmacol Exp Ther 1997; 282: 1242-6.
    • (1997) JPharmacol Exp Ther , vol.282 , pp. 1242-1246
    • Field, M.J.1    Holloman, E.F.2    McCleary, S.3
  • 194
    • 0031838031 scopus 로고    scopus 로고
    • S-(+)-3-isobutylgaba and itsstereoisomer reduces the amount of inflammation and hyperalgesiain an acute arthritis model in the rat
    • Houghton AK, Lu Y, Westlund KN. S-(+)-3-isobutylgaba and itsstereoisomer reduces the amount of inflammation and hyperalgesiain an acute arthritis model in the rat. J Pharmacol Exp Ther 1998;28: 533-8.
    • (1998) J Pharmacol Exp Ther , vol.28 , pp. 533-538
    • Houghton, A.K.1    Lu, Y.2    Westlund, K.N.3
  • 195
    • 0031883542 scopus 로고    scopus 로고
    • A summary of mechanistic hypothesesof gabapentin pharmacology
    • Taylor CP, Gee NS, Su TZ, et al. A summary of mechanistic hypothesesof gabapentin pharmacology. Epilepsy Res 1998; 29: 233-49.
    • (1998) Epilepsy Res , vol.29 , pp. 233-249
    • Taylor, C.P.1    Gee, N.S.2    Su, T.Z.3
  • 196
    • 0038702425 scopus 로고    scopus 로고
    • Cellular and molecularaction of the putative GABA-mimetic gabapentin
    • Maneuf YP, Gonzalez MI, Sutton KS, et al. Cellular and molecularaction of the putative GABA-mimetic gabapentin. Cell Mol LifeSci 2003; 60: 742-50.
    • (2003) Cell Mol LifeSci , vol.60 , pp. 742-750
    • Maneuf, Y.P.1    Gonzalez, M.I.2    Sutton, K.S.3
  • 197
    • 0034653399 scopus 로고    scopus 로고
    • Proliferation anddifferentiation of progenitor cells throughout the intact adult ratspinal cord
    • Horner PJ, Power AE, Kempermann G, et al. Proliferation anddifferentiation of progenitor cells throughout the intact adult ratspinal cord. J Neurosci 2000; 20: 2218-28.
    • (2000) J Neurosci , vol.20 , pp. 2218-2228
    • Horner, P.J.1    Power, A.E.2    Kempermann, G.3
  • 198
    • 0023881117 scopus 로고
    • Microglial cells but notastrocytes undergo mitosis following rat facial nerve axotomy
    • Graeber MB, Tetzlaff W, Streit WJ, et al. Microglial cells but notastrocytes undergo mitosis following rat facial nerve axotomy. Neurosci Lett 1988; 85: 317-21.
    • (1988) Neurosci Lett , vol.85 , pp. 317-321
    • Graeber, M.B.1    Tetzlaff, W.2    Streit, W.J.3
  • 200
    • 0026051875 scopus 로고
    • Staining ofglial fibrillary acidic protein (GFAP) in lumbar spinal cordincreases following a sciatic nerve constriction injury
    • Garrison CJ, Dougherty PM, Kajander KC, et al. Staining ofglial fibrillary acidic protein (GFAP) in lumbar spinal cordincreases following a sciatic nerve constriction injury. Brain Res 1991; 565: 1-7.
    • (1991) Brain Res , vol.565 , pp. 1-7
    • Garrison, C.J.1    Dougherty, P.M.2    Kajander, K.C.3
  • 201
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of thehuman genome
    • Venter JC, Adams MD, Myers EW, et al. The sequence of thehuman genome. Science 2001; 291: 1304-51.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 202
    • 33748310730 scopus 로고    scopus 로고
    • Phosphoprotein analysis: From proteins toproteomes
    • Delom F, Chevet E. Phosphoprotein analysis: from proteins toproteomes. Proteome Sci 2006; 4: 15.
    • (2006) Proteome Sci , vol.4 , pp. 15
    • Delom, F.1    Chevet, E.2
  • 203
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: The yin and yang ofprotein phosphorylation and signaling
    • Hunter T. Protein kinases and phosphatases: the yin and yang ofprotein phosphorylation and signaling. Cell 1995; 80: 225-36.
    • (1995) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 204
    • 25844444638 scopus 로고    scopus 로고
    • Central nervoussystem drug development: An integrative biomarker approach towardindividualized medicine
    • Gomez-Mancilla B, Marrer E, Kehren J, et al. Central nervoussystem drug development: An integrative biomarker approach towardindividualized medicine. NeuroRx 2010; 2: 683-95.
    • (2010) NeuroRx , vol.2 , pp. 683-695
    • Gomez-Mancilla, B.1    Marrer, E.2    Kehren, J.3
  • 205
    • 85036718858 scopus 로고    scopus 로고
    • Deutsch EW, Lam H, http://www.nature.com/embor/journal/v9/n5/full/embor200856.html-a1
    • Deutsch, E.W.1    Lam, H.2
  • 206
    • 43049127826 scopus 로고    scopus 로고
    • PeptideAtlas: A resourcefor target selection for emerging targeted proteomics workflows
    • Aebersold R. PeptideAtlas: a resourcefor target selection for emerging targeted proteomics workflows. EMBO Rep 2008; 9: 429-34.
    • (2008) EMBO Rep , vol.9 , pp. 429-434
    • Aebersold, R.1
  • 207
    • 76649124557 scopus 로고    scopus 로고
    • A gene-centric HumanProteome project
    • HUPO - the Human Proteome organization
    • HUPO - the Human Proteome organization. A gene-centric HumanProteome project. Mol Cell Proteomics 2010; 9: 427-9.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 427-429
  • 208
    • 61349120181 scopus 로고    scopus 로고
    • Should the human proteome project be gene- or protein-centric?
    • Hochstrasser, D. Should the human proteome project be gene- or protein-centric? J Proteome Res 2008; 7: 5071.
    • (2008) J Proteome Res , vol.7 , pp. 5071
    • Hochstrasser, D.1
  • 209
    • 79955689873 scopus 로고    scopus 로고
    • Tutorial on Drug Development for Central Nervous System
    • Yoon H, Kim J. Tutorial on Drug Development for Central Nervous System. Interdisciplinary Bio Central 2010; 2: 1-5.
    • (2010) Interdisciplinary Bio Central , vol.2 , pp. 1-5
    • Yoon, H.1    Kim, J.2
  • 210
    • 72149123967 scopus 로고    scopus 로고
    • Total and phosphorylated tau protein as biological markers of Alzheimer's disease
    • Hampel H, Blennow K, Shaw LM, et al. Total and phosphorylated tau protein as biological markers of Alzheimer's disease. Exp Gerontol 2010; 45: 30-40.
    • (2010) Exp Gerontol , vol.45 , pp. 30-40
    • Hampel, H.1    Blennow, K.2    Shaw, L.M.3


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