-
1
-
-
30144443464
-
Molecular targets versus models for new antiepileptic drug discovery
-
Rogawski MA: Molecular targets versus models for new antiepileptic drug discovery. Epilepsy Res, 2006; 68: 22-28
-
(2006)
Epilepsy Res
, vol.68
, pp. 22-28
-
-
Rogawski, M.A.1
-
2
-
-
3042558629
-
Antiepileptic drugs: Indications other than epilepsy
-
Spina E, Perugi G: Antiepileptic drugs: indications other than epilepsy. Epileptic disorders 2004; 6: 57-75
-
(2004)
Epileptic disorders
, vol.6
, pp. 57-75
-
-
Spina, E.1
Perugi, G.2
-
3
-
-
3142774111
-
The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions
-
Rogawski MA, Löscher W: The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nature Medicine, 2004; 10: 685-92
-
(2004)
Nature Medicine
, vol.10
, pp. 685-692
-
-
Rogawski, M.A.1
Löscher, W.2
-
5
-
-
85047690079
-
An introduction to antiepileptic drugs
-
Perucca E: An introduction to antiepileptic drugs. Epilepsia, 2005; 46: 31-37
-
(2005)
Epilepsia
, vol.46
, pp. 31-37
-
-
Perucca, E.1
-
6
-
-
0028300225
-
Nuclear magnetic resonance detection of increased GABA in vigabatrin-treated rats in vivo
-
Preece NE, Jackson GD, Houseman JA et al: Nuclear magnetic resonance detection of increased GABA in vigabatrin-treated rats in vivo. Epilepsia, 1994; 35: 431-36
-
(1994)
Epilepsia
, vol.35
, pp. 431-436
-
-
Preece, N.E.1
Jackson, G.D.2
Houseman, J.A.3
-
7
-
-
0024361868
-
Clinical pharmacology of vigabatrin
-
Schechter PJ: Clinical pharmacology of vigabatrin. Br J Clin Pharmacol, 1989; 27: 19S-22
-
(1989)
Br J Clin Pharmacol
, vol.27
-
-
Schechter, P.J.1
-
8
-
-
0035069775
-
Visual field defects with vigabatrin: Epidemiology and therapeutic implications
-
Kälviäinen R, Nousiainen I: Visual field defects with vigabatrin: epidemiology and therapeutic implications. CNS Drugs, 2001; 15: 217-30
-
(2001)
CNS Drugs
, vol.15
, pp. 217-230
-
-
Kälviäinen, R.1
Nousiainen, I.2
-
9
-
-
0035943079
-
Visual field constriction: Accumulation of vigabatrin but not tiagabine in the retina
-
Sills GJ, Patsalos PN, Butler E et al: Visual field constriction: accumulation of vigabatrin but not tiagabine in the retina. Neurology, 2001; 57: 196-200
-
(2001)
Neurology
, vol.57
, pp. 196-200
-
-
Sills, G.J.1
Patsalos, P.N.2
Butler, E.3
-
10
-
-
0037373430
-
A controlled study comparing visual function in patients treated with vigabatrin and tiagabine
-
Krauss GL, Johnson MA, Sheth S, Miller NR: A controlled study comparing visual function in patients treated with vigabatrin and tiagabine. J Neurosurg Psychiatry, 2003; 74: 339-43
-
(2003)
J Neurosurg Psychiatry
, vol.74
, pp. 339-343
-
-
Krauss, G.L.1
Johnson, M.A.2
Sheth, S.3
Miller, N.R.4
-
11
-
-
0035009415
-
The new generation of GABA enhancers. Potential in the treatment of epilepsy
-
Czuczwar SJ, Patsalos PN: The new generation of GABA enhancers. Potential in the treatment of epilepsy. CNS Drugs, 2001; 15: 339-50
-
(2001)
CNS Drugs
, vol.15
, pp. 339-350
-
-
Czuczwar, S.J.1
Patsalos, P.N.2
-
12
-
-
28844461167
-
The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: Results of a placebo-controlled study
-
Pollack Mh, Roy-Byrne PP, Van Ameringen M et al: The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study. J Clin Psychiatry, 2005; 66: 1401-8
-
(2005)
J Clin Psychiatry
, vol.66
, pp. 1401-1408
-
-
Pollack, M.1
Roy-Byrne, P.P.2
Van Ameringen, M.3
-
13
-
-
0036402177
-
Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy
-
Löscher W: Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy. CNS Drugs, 2002; 16: 669-94
-
(2002)
CNS Drugs
, vol.16
, pp. 669-694
-
-
Löscher, W.1
-
14
-
-
4243491268
-
Valproic acid. Mechanisms of action
-
Levy RH, Mattson RH, Meldrum BS, Perucca E eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins
-
th ed. Philadelphia: Lippincott Williams & Wilkins, 2002; 767-779
-
(2002)
Antiepileptic drugs
, pp. 767-779
-
-
Löscher, W.1
-
15
-
-
0034257051
-
Mechanisms of action of valproate: A commentary
-
Johannessen CU: Mechanisms of action of valproate: a commentary. Neurochem Int, 2000; 37: 103-10
-
(2000)
Neurochem Int
, vol.37
, pp. 103-110
-
-
Johannessen, C.U.1
-
16
-
-
0035652349
-
The acute effect of valproate on cerebral energy metabolism in mice
-
Johannessen CU, Petersen D, Fonnum F, Hassel B: The acute effect of valproate on cerebral energy metabolism in mice. Epilepsy Res, 2001; 47: 247-56
-
(2001)
Epilepsy Res
, vol.47
, pp. 247-256
-
-
Johannessen, C.U.1
Petersen, D.2
Fonnum, F.3
Hassel, B.4
-
17
-
-
0026724502
-
Pharmacological, toxicological and neurochemical effects of delta 2(E)-valproate in animals
-
Löscher W: Pharmacological, toxicological and neurochemical effects of delta 2(E)-valproate in animals. Pharm Weekbl Sci, 1992; 14: 139-43
-
(1992)
Pharm Weekbl Sci
, vol.14
, pp. 139-143
-
-
Löscher, W.1
-
18
-
-
0042868293
-
Valproate: Past, Present, and Future
-
Johannessen CU, Johannessen SI: Valproate: Past, Present, and Future. CNS Drug Reviews, 2003; 9: 199-216
-
(2003)
CNS Drug Reviews
, vol.9
, pp. 199-216
-
-
Johannessen, C.U.1
Johannessen, S.I.2
-
20
-
-
0038771254
-
Search for a common mechanism of mood stabilizers
-
Harwood AJ, Agam G: Search for a common mechanism of mood stabilizers. Biochem Pharmacol, 2003; 66: 179-89
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 179-189
-
-
Harwood, A.J.1
Agam, G.2
-
21
-
-
20544478555
-
Neurochemical underpinnings in bipolar disorder and epilepsy
-
Anmann B, Grunze H: Neurochemical underpinnings in bipolar disorder and epilepsy. Epilepsia, 2005; 46: 26-30
-
(2005)
Epilepsia
, vol.46
, pp. 26-30
-
-
Anmann, B.1
Grunze, H.2
-
22
-
-
0141454852
-
Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis
-
Ju S, Greenberg ML: Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis. Mol Microbiol, 2003; 49: 1595-603
-
(2003)
Mol Microbiol
, vol.49
, pp. 1595-1603
-
-
Ju, S.1
Greenberg, M.L.2
-
23
-
-
0038383690
-
Cellular mechanisms and second messengers: Relevance to the psychopharmacology of bipolar disorders
-
Brunello N, Tascedda F: Cellular mechanisms and second messengers: relevance to the psychopharmacology of bipolar disorders. Int J Neuropsychopharmacol, 2003; 6: 181-89
-
(2003)
Int J Neuropsychopharmacol
, vol.6
, pp. 181-189
-
-
Brunello, N.1
Tascedda, F.2
-
24
-
-
27744522143
-
Altered gene expression in mice treated with the mood stabilizer sodium valproate
-
Chetcuti A, Adams LJ, Mitchell PB, Schofield PR: Altered gene expression in mice treated with the mood stabilizer sodium valproate. Int J Neuropsychopharmacol, 2005; 28: 1-10
-
(2005)
Int J Neuropsychopharmacol
, vol.28
, pp. 1-10
-
-
Chetcuti, A.1
Adams, L.J.2
Mitchell, P.B.3
Schofield, P.R.4
-
25
-
-
23644443835
-
Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release
-
Ichikawa J, Chung YC, Dai J, Meltzer HY: Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release. Brain Res, 2005; 1052: 56-62
-
(2005)
Brain Res
, vol.1052
, pp. 56-62
-
-
Ichikawa, J.1
Chung, Y.C.2
Dai, J.3
Meltzer, H.Y.4
-
26
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Göttlicher M Minucci, S Zhu P et al: Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J, 2001; 20: 6969-78
-
(2001)
EMBO J
, vol.20
, pp. 6969-6978
-
-
Göttlicher, M.1
Minucci, S.2
Zhu, P.3
-
27
-
-
0035965343
-
Histone deacetylases is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel CJ et al: Histone deacetylases is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem, 2001; 276: 36734-41
-
(2001)
J Biol Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
-
28
-
-
0141988725
-
Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis
-
Dou H, Birusingh K, Faraci J et al: Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis. J Neurosci, 2003; 23: 9162-70
-
(2003)
J Neurosci
, vol.23
, pp. 9162-9170
-
-
Dou, H.1
Birusingh, K.2
Faraci, J.3
-
29
-
-
33646850050
-
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01
-
Yeow WS, Ziauddin MF, Maxhimer JB et al: Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. Br J Cancer, 2006; 22: 1436-45
-
(2006)
Br J Cancer
, vol.22
, pp. 1436-1445
-
-
Yeow, W.S.1
Ziauddin, M.F.2
Maxhimer, J.B.3
-
30
-
-
18044381744
-
Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active constitutional isomers and derivatives
-
Eyal S, Yagen B, Shimshoni J, Bialer M: Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active constitutional isomers and derivatives. Biochem Pharmacol, 2005; 69: 1501-8
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 1501-1508
-
-
Eyal, S.1
Yagen, B.2
Shimshoni, J.3
Bialer, M.4
-
31
-
-
4644301804
-
-
Bialer M, Johannessen SI, Kupferberg HJ et al: Progress report on new antiepileptic drugs: a summary of the Seventh Eilat conference (Eilat VII). Epilepsy Res, 2004; 61: 1-48
-
Bialer M, Johannessen SI, Kupferberg HJ et al: Progress report on new antiepileptic drugs: a summary of the Seventh Eilat conference (Eilat VII). Epilepsy Res, 2004; 61: 1-48
-
-
-
-
32
-
-
0037310265
-
Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model
-
Stratton SC, Large CH, Cox B et al: Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model. Epilepsy Res, 2003; 53: 95-106
-
(2003)
Epilepsy Res
, vol.53
, pp. 95-106
-
-
Stratton, S.C.1
Large, C.H.2
Cox, B.3
-
33
-
-
3042748137
-
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch B, Lambeng N, Nocka K et al: The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci, 2004; 101: 9861-66
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 9861-9866
-
-
Lynch, B.1
Lambeng, N.2
Nocka, K.3
-
34
-
-
0036120515
-
Levetiracetam opposes the action of GABAA antagonists in hypothalamic neurones
-
Poulain P, Margineanu DG: Levetiracetam opposes the action of GABAA antagonists in hypothalamic neurones. Neuropharmacol, 2002; 42: 346-52
-
(2002)
Neuropharmacol
, vol.42
, pp. 346-352
-
-
Poulain, P.1
Margineanu, D.G.2
-
35
-
-
0035987775
-
The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents
-
Rigo JM, Hans G, Nguyen L et al: The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. Br J Pharmacol, 2002; 136: 659-72
-
(2002)
Br J Pharmacol
, vol.136
, pp. 659-672
-
-
Rigo, J.M.1
Hans, G.2
Nguyen, L.3
-
36
-
-
7244248678
-
Pilot efficacy and tolerability: A randomized, placebo-controlled trial of levetiracetam for essential tremor
-
Handforth A, Martin FC: Pilot efficacy and tolerability: a randomized, placebo-controlled trial of levetiracetam for essential tremor. Mov Disord, 2004; 19: 1215-21
-
(2004)
Mov Disord
, vol.19
, pp. 1215-1221
-
-
Handforth, A.1
Martin, F.C.2
-
37
-
-
15244341695
-
The effect of levetiracetam on essential tremor
-
Bushara KO, Malik T, Exconde RE: The effect of levetiracetam on essential tremor. Neurology, 2005; 64: 1078-80
-
(2005)
Neurology
, vol.64
, pp. 1078-1080
-
-
Bushara, K.O.1
Malik, T.2
Exconde, R.E.3
-
38
-
-
17244372257
-
Molecular pharmacology of topiramate: Managing seizures and preventing migraine
-
White HS: Molecular pharmacology of topiramate: managing seizures and preventing migraine. Headache, 2005; 45: S48-56
-
(2005)
Headache
, vol.45
-
-
White, H.S.1
-
39
-
-
1942436861
-
Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist
-
Kaminski RM, Banerjee M, Rogawski MA: Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology, 2004; 46: 1097-104
-
(2004)
Neuropharmacology
, vol.46
, pp. 1097-1104
-
-
Kaminski, R.M.1
Banerjee, M.2
Rogawski, M.A.3
-
40
-
-
23944506267
-
Topiramate add-on in treatment-resistant schizophrenia: A randomized, double-blind, placebo-controlled, crossover trial
-
Tiihonen J, Halonen P, Wahlbeck K et al: Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial. J Clin Psychiatry, 2005; 66: 1012-15
-
(2005)
J Clin Psychiatry
, vol.66
, pp. 1012-1015
-
-
Tiihonen, J.1
Halonen, P.2
Wahlbeck, K.3
-
42
-
-
0037373028
-
Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels
-
Liu G, Yarov-Yarovoy V, Nobbs M et al: Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels. Neuropharmacol, 2003; 44: 413-22
-
(2003)
Neuropharmacol
, vol.44
, pp. 413-422
-
-
Liu, G.1
Yarov-Yarovoy, V.2
Nobbs, M.3
-
43
-
-
0031754721
-
+ channels
-
+ channels. Mol Pharmacol, 1998; 54: 712-21
-
(1998)
Mol Pharmacol
, vol.54
, pp. 712-721
-
-
Kuo, X.1
-
44
-
-
0031756758
-
Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder
-
Xie X, Hagan RM: Cellular and molecular actions of lamotrigine: possible mechanisms of efficacy in bipolar disorder. Neuropsychobiology, 1998; 38: 119-30
-
(1998)
Neuropsychobiology
, vol.38
, pp. 119-130
-
-
Xie, X.1
Hagan, R.M.2
-
45
-
-
0036321057
-
Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
-
Poolos NP, Migliore M, Johnston D: Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites. Nat Neurosci, 2002; 5: 767-74
-
(2002)
Nat Neurosci
, vol.5
, pp. 767-774
-
-
Poolos, N.P.1
Migliore, M.2
Johnston, D.3
-
46
-
-
0141593927
-
Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders
-
Ketter TA, Manji HK, Post RM: Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders. J Clin Psychopharmacol, 2003; 23: 484-95
-
(2003)
J Clin Psychopharmacol
, vol.23
, pp. 484-495
-
-
Ketter, T.A.1
Manji, H.K.2
Post, R.M.3
-
47
-
-
18044398787
-
Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder
-
Muzina DJ, Elhaj O, Gajwani P et al: Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder. Acta Psychiatr Scand, 2005; 111: 21-28
-
(2005)
Acta Psychiatr Scand
, vol.111
, pp. 21-28
-
-
Muzina, D.J.1
Elhaj, O.2
Gajwani, P.3
-
48
-
-
17044399816
-
Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids
-
Ahmad S, Fowler LJ, Whitton PS: Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids. Epilepsy Res, 2005; 63: 141-49
-
(2005)
Epilepsy Res
, vol.63
, pp. 141-149
-
-
Ahmad, S.1
Fowler, L.J.2
Whitton, P.S.3
-
49
-
-
15344351223
-
What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs?
-
Schmidt D, Elger CE: What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs? Epilepsy Behav, 2004; 5: 627-35
-
(2004)
Epilepsy Behav
, vol.5
, pp. 627-635
-
-
Schmidt, D.1
Elger, C.E.2
-
50
-
-
30844440069
-
The mechanisms of action of gabapentin and pregabalin
-
Sills GJ: The mechanisms of action of gabapentin and pregabalin. Curr Opin Pharmacol, 2006; 6: 108-13
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 108-113
-
-
Sills, G.J.1
-
51
-
-
0035032465
-
Calcium channel alpha(2)delta subunits-structure and gabapentin binding
-
Marais E, Klugbauer N, Hofman F: Calcium channel alpha(2)delta subunits-structure and gabapentin binding. Mol Pharmacol, 2001; 59: 1243-48
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1243-1248
-
-
Marais, E.1
Klugbauer, N.2
Hofman, F.3
-
52
-
-
33644896021
-
Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: An ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice
-
Bian F, Li Z, Offord J et al: Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice. Brain Res, 2006; 1075: 68-80
-
(2006)
Brain Res
, vol.1075
, pp. 68-80
-
-
Bian, F.1
Li, Z.2
Offord, J.3
-
53
-
-
0035164999
-
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action
-
Ng GY, Bertrand S, Sullivan R et al: Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Mol Pharmacol, 2001; 59: 144-52
-
(2001)
Mol Pharmacol
, vol.59
, pp. 144-152
-
-
GY, N.1
Bertrand, S.2
Sullivan, R.3
-
54
-
-
1542316211
-
Migraine throughout the life cycle. Treatment through the ages
-
Landy S: Migraine throughout the life cycle. Treatment through the ages. Neurology, 2004; 62: S2-8
-
(2004)
Neurology
, vol.62
-
-
Landy, S.1
-
55
-
-
1642457196
-
Use-dependent inhibition of the N-methyl-D-aspartate currents by felbamate: A gating modifier with selective binding to the desensitized channels
-
Kuo CC, Lin BJ, Chang HR, Hsieh CP: Use-dependent inhibition of the N-methyl-D-aspartate currents by felbamate: a gating modifier with selective binding to the desensitized channels. Mol Pharmacol, 2004; 65: 370-80
-
(2004)
Mol Pharmacol
, vol.65
, pp. 370-380
-
-
Kuo, C.C.1
Lin, B.J.2
Chang, H.R.3
Hsieh, C.P.4
-
56
-
-
0011043676
-
Neuroprotective effects of the anticonvulsant, fluorofelbamate
-
Wallis RA, Panizzon KL, Niquet J et al: Neuroprotective effects of the anticonvulsant, fluorofelbamate. Epilepsia, 2000; 41: 16
-
(2000)
Epilepsia
, vol.41
, pp. 16
-
-
Wallis, R.A.1
Panizzon, K.L.2
Niquet, J.3
-
57
-
-
0023186374
-
Zonisamide enhances slow sodium inactivation in Myxicola
-
Schauf CL: Zonisamide enhances slow sodium inactivation in Myxicola. Brain Res, 1987; 413: 185-88
-
(1987)
Brain Res
, vol.413
, pp. 185-188
-
-
Schauf, C.L.1
-
58
-
-
0026643459
-
Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex
-
Suzuki S, Kawakami K, Nishimura S et al: Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex. Epilepsy Res, 1992; 12: 21-27
-
(1992)
Epilepsy Res
, vol.12
, pp. 21-27
-
-
Suzuki, S.1
Kawakami, K.2
Nishimura, S.3
-
59
-
-
0031980480
-
The anticonvulsant zonisamide scavenges free radicals
-
Mori A, Noda Y, Packer L: The anticonvulsant zonisamide scavenges free radicals. Epilepsy Res, 1998; 30: 153-58
-
(1998)
Epilepsy Res
, vol.30
, pp. 153-158
-
-
Mori, A.1
Noda, Y.2
Packer, L.3
-
60
-
-
14044261758
-
Effect of zonisamide on essential tremor: A pilot crossover study in comparison with arotinolol
-
Morita S, Miwa H, Kondo T: Effect of zonisamide on essential tremor: a pilot crossover study in comparison with arotinolol. Parkinsonism Relat Disord, 2005; 11: 101-3
-
(2005)
Parkinsonism Relat Disord
, vol.11
, pp. 101-103
-
-
Morita, S.1
Miwa, H.2
Kondo, T.3
-
61
-
-
27144484863
-
Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse
-
Tanabe M, Sakaue A, Takasu K et al: Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. Nauyn Schmiedebergs Arch Pharmacol, 2005; 372: 107-14
-
(2005)
Nauyn Schmiedebergs Arch Pharmacol
, vol.372
, pp. 107-114
-
-
Tanabe, M.1
Sakaue, A.2
Takasu, K.3
-
62
-
-
0033862433
-
Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels
-
Wickenden AD, Yu W, Zou A et al: Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels. Mol Pharmacol, 2000; 58: 591-600
-
(2000)
Mol Pharmacol
, vol.58
, pp. 591-600
-
-
Wickenden, A.D.1
Yu, W.2
Zou, A.3
-
63
-
-
0034677733
-
The novel anticonvulsant retigabine activates M-currents in Chineese hamster ovary-cells transfected with human KCNQ2/3 subunits
-
Rundfeldt C, Netzer R: The novel anticonvulsant retigabine activates M-currents in Chineese hamster ovary-cells transfected with human KCNQ2/3 subunits. Neurosci Lett, 2000; 281: 73-76
-
(2000)
Neurosci Lett
, vol.281
, pp. 73-76
-
-
Rundfeldt, C.1
Netzer, R.2
-
64
-
-
28044458967
-
Antiepileptic drug discovery: Lessons from the past and future challenges
-
Klitgaard H: Antiepileptic drug discovery: lessons from the past and future challenges. Acta Neurol Scand, 2005; 181: 68-72
-
(2005)
Acta Neurol Scand
, vol.181
, pp. 68-72
-
-
Klitgaard, H.1
-
65
-
-
33747049831
-
Diverse mechanisms of antiepileptic drugs in the development pipeline
-
in press
-
Rogawski MA: Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res, 2006; in press
-
(2006)
Epilepsy Res
-
-
Rogawski, M.A.1
-
66
-
-
0036247871
-
Non-competitive AMPA antagonists of 2,3-benzodiazepine type
-
Sólyom S, Tarnawa I: Non-competitive AMPA antagonists of 2,3-benzodiazepine type. Curr Pharm, 2002; 8: 913-39
-
(2002)
Curr Pharm
, vol.8
, pp. 913-939
-
-
Sólyom, S.1
Tarnawa, I.2
-
67
-
-
28044453713
-
Schizophrenia-related sensorimotor deficit links alpha-3-containing GABAA receptors to a dopamine hyperfunction
-
Yee BK, Keist R, von Boehmer L et al: Schizophrenia-related sensorimotor deficit links alpha-3-containing GABAA receptors to a dopamine hyperfunction. Proc Natl Acad Sci, 2005; 22(102): 17154-59
-
(2005)
Proc Natl Acad Sci
, vol.22
, Issue.102
, pp. 17154-17159
-
-
Yee, B.K.1
Keist, R.2
von Boehmer, L.3
-
69
-
-
30844463216
-
Glutamate- and GABA-based CNS therapeutics
-
Foster AC, Kemp JA: Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol, 2006; 6: 7-17
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 7-17
-
-
Foster, A.C.1
Kemp, J.A.2
-
70
-
-
30844468174
-
B receptors: A site of therapeutic benefit
-
B receptors: a site of therapeutic benefit. Curr Opin Pharmacol, 2006; 6: 37-43
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 37-43
-
-
Bowery, N.G.1
-
71
-
-
24944509512
-
Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala
-
Gryder DS, Castaneda DC, Rogawski MA: Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala. J Neurochem, 2005; 94: 1728-38
-
(2005)
J Neurochem
, vol.94
, pp. 1728-1738
-
-
Gryder, D.S.1
Castaneda, D.C.2
Rogawski, M.A.3
-
72
-
-
30844468842
-
Glutamate-based therapeutic approaches: Ampakines
-
Lynch G: Glutamate-based therapeutic approaches: ampakines. Curr Opin Pharmacol, 2006; 6: 82-88
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 82-88
-
-
Lynch, G.1
-
73
-
-
30844439634
-
Glutamate-based therapeutic approaches: Clinical trials with NMDA antagonists
-
Muir KW: Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists. Curr Opin Pharmacol, 2006; 6: 53-60
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 53-60
-
-
Muir, K.W.1
-
74
-
-
30844451008
-
Glutamate-based approaches: NR2B receptor antagonists
-
Gogas KR: Glutamate-based approaches: NR2B receptor antagonists. Curr Opin Pharmacol, 2006; 6: 68-74
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 68-74
-
-
Gogas, K.R.1
-
75
-
-
30844432624
-
Glutamate-based therapeutic approaches: Allosteric modulators of metabotropic glutamate receptors
-
Marino MJ, Conn PJ: Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors. Curr Opin Pharmacol, 2006; 6: 98-102
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 98-102
-
-
Marino, M.J.1
Conn, P.J.2
-
76
-
-
30844465708
-
Glutamate-based therapeutic approaches: Targeting the glutamate transport system
-
Dunlop J: Glutamate-based therapeutic approaches: targeting the glutamate transport system. Curr Opin Pharmacol, 2006; 6: 103-7
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 103-107
-
-
Dunlop, J.1
-
77
-
-
24744447002
-
Astrocytes get in the act in epilepsy
-
Rogawski M: Astrocytes get in the act in epilepsy. Nature Medicine, 2005; 11: 919-20
-
(2005)
Nature Medicine
, vol.11
, pp. 919-920
-
-
Rogawski, M.1
-
79
-
-
30844441616
-
Functional implications of transmitter co-release: Glutamate and GABA share the load
-
Seal R, Edwards RH: Functional implications of transmitter co-release: glutamate and GABA share the load. Curr Opin Pharmacol, 2006; 6: 114-19
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 114-119
-
-
Seal, R.1
Edwards, R.H.2
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