Proteomic Analysis of Protein Changes Developing in Rat Hippocampus after Chronic Antidepressant Treatment: Implications for Depressive Disorders and Future Therapies

Journal of Neuroscience Research

Volumn 75, Issue 4, 2004, Pages 451-460

  Khawaja, Xavier ^a   Xu, Jun ^a   Liang, Jin Jun ^b   Barrett, James E ^c  

^a CN8000   (United States)

^b SANOFI   (France)

^c Memory Pharmaceuticals Corporation   (United States)

Author keywords

BrdU; Hippocampus; MALDI TOF; Neurogenesis; Proteomics

Indexed keywords

ADENINE PHOSPHORIBOSYLTRANSFERASE; ALPHA ENOLASE; ANTIOXIDANT; ANTIOXIDANT PROTEIN 2; BROXURIDINE; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; DIHYDROPYRIMIDINASE; DIHYDROPYRIMIDINASE RELATED PROTEIN 2; DIMETHYLARGININASE; DOPACHROME TAUTOMERASE; ENOLASE; FLUOXETINE; GLIA MATURATION FACTOR; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN 10; HIPPOCAMPAL CHOLINERGIC NEUROSTIMULATING PEPTIDE; HYDROXYSTEROID SULFOTRANSFERASE; HYDROXYSTEROID SULFOTRANSFERASE A; LYMPHOTACTIN; NEUROPEPTIDE; PROBASIN; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE E1; RAS PROTEIN; RAS RELATED PROTEIN 1B; RAS RELATED PROTEIN 4A; RIBOSOME PROTEIN; SEMAPHORIN; SOMATOMEDIN C; UNCLASSIFIED DRUG; VENLAFAXINE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DEPRESSION; HIPPOCAMPUS; MAJOR DEPRESSION; MALE; MASS SPECTROMETRY; NERVE CELL PLASTICITY; NERVE REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; PROTEOMICS; RAT; SEROTONINERGIC TRANSMISSION; SILVER STAINING; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; ANTIDEPRESSIVE AGENTS; CELL DIVISION; DEPRESSIVE DISORDER; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HIPPOCAMPUS; MALE; PROTEIN BIOSYNTHESIS; PROTEINS; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0742287855     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10869     Document Type: Article

References (40)

1. Aberg MA, Aberg ND, Hedbacker H, Oscarsson J, Eriksson PS. 2000. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus. J Neurosci 20:2896-2903.
2. Anderson MF, Aberg MA, Nilsson M, Eriksson PS. 2002. Insulin-like growth factor-I and neurogenesis in the adult mammalian brain. Brain Res Dev Brain Res 134:115-122.
3. Bourin M, Chue P, Guillon Y. 2001. Paroxetine: a review. CNS Drug Rev 7:25-47.
4. Cheng CM, Cohen M, Tseng V, Bondy CA. 2001. Endogenous IGF1 enhances cell survival in the postnatal dentate gyrus. J Neurosci Res 64:341-347.
5. Frazer A. 1997. Pharmacology of antidepressants. J Clin Psychopharmacol 17(Suppl):2-18.
6. Fuchs E, Gould E. 2000. Mini-review: in vivo neurogenesis in the adult brain: regulation and functional implications. Eur J Neurosci 12:2211-2214.
7. Fukata Y, Itoh TJ, Kimura T, Menager C, Nishimura T, Shiromizu T, Watanabe H, Inagaki N, Iwamatsu A, Hotani H, Kaibuchi K. 2002. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nat Cell Biol 8:583-591.
8. Gage FH, Kempermann G, Palmer TD, Peterson DA, Ray J. 1998. Multipotent progenitor cells in the adult dentate gyrus. J Neurobiol 36:249-266.
9. Griffin LD, Conrad SC, Mellon SH. 2001. Current perspectives on the role of neurosteroids in PMS and depression. Int Rev Neurobiol 46:479-492.
10. Griffin LD, Mellon SH. 1999. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci USA 96:13512-13517.
11. Hirose T, Kawabuchi M, Tamaru T, Okumura N, Nagai K, Okada M. 2000. Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain. Eur J Biochem 267:2113-2121.
12. Inagaki N, Chihara K, Arimura N, Menager C, Kawano Y, Matsuo N, Nishimura T, Amano M, Kaibuchi K. 2001. CRMP-2 induces axons in cultured hippocampal neurons. Nat Neurosci 4:781-782.
13. Iwase T, Ojika K, Matsukawa N, Nishino H, Yamamoto T, Okada H, Fujimori O, Ueda R. 2001. Muscarinic cholinergic and glutamatergic reciprocal regulation of expression of hippocampal cholinergic neurostimulating peptide precursor protein gene in rat hippocampus. Neuroscience 102:341-352.
14. Kempermann G. 2002. Regulation of adult hippocampal neurogenesis-implications for novel theories of major depression. Bipolar Disord 4:17-33.
15. Kimoto T, Tsurugizawa T, Ohta Y, Makino J, Tamura Ho, Hojo Y, Takata N, Kawato S. 2001. Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology 142:3578-3589.
16. Lissens W, De Meirleir L, Seneca S, Liebaers I, Brown GK, Brown RM, Ito M, Naito E, Kuroda Y, Kerr DS, Wexler ID, Patel MS, Robinson BH, Seyda A. 2000. Mutations in the X-linked pyruvate dehydrogenase (E1) alpha subunit gene (PDHA1) in patients with a pyruvate dehydrogenase complex deficiency. Hum Mutat 15:209-219.
17. Liu BP, Strittmatter SM. 2001. Semaphorin-mediated axonal guidance via Rho-related G proteins. Curr Opin Cell Biol 13:619-626.
18. Malberg JE, Eisch AJ, Nestler EJ, Duman RS. 2000. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20:9104-9110.
19. Manji HK, Drevets WC, Charney DS. 2001. The cellular neurobiology of depression. Nat Med 7:541-547.
20. Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. 2002. Neurobiology of depression. Neuron 34:13-25.
21. Netto LE, Kowaltowski AJ, Castilho RF, Vercesi AE. 2002. Thiol enzymes protecting mitochondria against oxidative damage. Methods Enzymol 348:260-270.
22. Ojika K, Mitake S, Tohdoh N, Appel SH, Otsuka Y, Katada E, Matsukawa N. 2000. Hippocampal cholinergic neurostimulating peptides (HCNP). Prog Neurobiol 60:37-83.
23. Okuda T, Cleveland JL, Downing JR. 1992. PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 7:2249-2258.
24. Paxinos G, Watson C. 1986. The Rat Brain in Stereotaxic Coordinates. Second Edition. New York: Academic Press.
25. Phelan SA. 1999. AOP2 (antioxidant protein 2): structure and function of a unique thiol-specific antioxidant. Antioxid Redox Signal 1:571-84.
26. Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK. 1993. The de facto mental and addictive disorders service system. Epidemiologic Catchment Area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiatry 50:85-94.
27. Rupprecht R, Holsboer F. 2001. Neuroactive steroids in neuropsychopharmacology. Int Rev Neurobiol 46:461-477.
28. Sheline YI, Sanghavi M, Mintun MA, Gado MH. 1999. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J Neurosci 19:5034-5043.
29. Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. 2002. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 22:3251-3261.
30. Skaper SD, Moore SE, Walsh FS. 2001. Cell signalling cascades regulating neuronal growth-promoting and inhibitory cues. Prog Neurobiol 65:593-608.
31. Song H, Ming G, He Z, Lehmann M, McKerracher L, Tessier-Lavigne M, Poo M. 1998. Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science 281:1515-1518.
32. Song HJ, Ming GL, Poo MM. 1997. cAMP-induced switching in turning direction of nerve growth cones. Nature 388:275-279.
33. Tran CT, Fox MF, Vallance P, Leiper JM. 2000. Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68:101-105.
34. van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. 2002. Functional neurogenesis in the adult hippocampus. Nature 415:1030-1034.
35. Wang LH, Strittmatter SM. 1996. A family of rat CRMP genes is differentially expressed in the nervous system. J Neurosci 16:6197-6207.
36. Wang BR, Zaheer A, Lim R. 1992. Polyclonal antibody localizes glia maturation factor beta-like immunoreactivity in neurons and glia. Brain Res 591:1-7.
37. Yeung K, Janosch P, McFerran B, Rose DW, Mischak H, Sedivy JM, Kolch W. 2000. Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein. Mol Cell Biol 20:3079-3085.
38. Yildiz F, Erden BF, Ulak G, Utkan T, Gacar N. 2000. Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacol 149:41-44.
39. Zaheer A, Lim R. 1996. In vitro inhibition of MAP kinase (ERK1/ERK2) activity by phosphorylated glia maturation factor (GMF). Biochemistry 35:6283-6288.
40. Zaheer A, Weiss JL, Goyal P, Lim R. 1999. Enhanced expression of neurotrophic factors by C6 rat glioma cells after transfection with glia maturation factor. Neurosci Lett 265:203-206.