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Volumn 9, Issue 3, 2011, Pages 321-332

Effects of insulin on the vasculature

Author keywords

Atherosclerosis; Insulin; Restenosis

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; INSULIN; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 79955640848     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016111795495558     Document Type: Review
Times cited : (30)

References (212)
  • 1
    • 33746465014 scopus 로고    scopus 로고
    • Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association
    • Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Diabetes Care 2006; 29: 1697-9.
    • (2006) Diabetes Care , vol.29 , pp. 1697-1699
    • Eckel, R.H.1    Kahn, R.2    Robertson, R.M.3    Rizza, R.A.4
  • 2
    • 0034127099 scopus 로고    scopus 로고
    • Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status
    • Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status. J Am Coll Cardiol 2000; 35: 1122-9.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1122-1129
  • 3
    • 0035979350 scopus 로고    scopus 로고
    • Clinical and economic impact of diabetes mellitus on percutaneous and surgical treatment of multivessel coronary disease patients: Insights from the Arterial Revascularization Therapy Study (ARTS) trial
    • Abizaid A, Costa MA, Centemero M, et al. Clinical and economic impact of diabetes mellitus on percutaneous and surgical treatment of multivessel coronary disease patients: insights from the Arterial Revascularization Therapy Study (ARTS) trial. Circulation 2001; 104: 533-8.
    • (2001) Circulation , vol.104 , pp. 533-538
    • Abizaid, A.1    Costa, M.A.2    Centemero, M.3
  • 4
    • 34247483998 scopus 로고    scopus 로고
    • Increasing cardiovascular disease burden due to diabetes mellitus: The Framingham Heart Study
    • Fox CS, Coady S, Sorlie PD, et al. Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation 2007; 115: 1544-50.
    • (2007) Circulation , vol.115 , pp. 1544-1550
    • Fox, C.S.1    Coady, S.2    Sorlie, P.D.3
  • 5
    • 33646239391 scopus 로고    scopus 로고
    • Efficacy of drug eluting stents in patients with and without diabetes mellitus: Indirect comparison of controlled trials
    • Stettler C, Allemann S, Egger M, Windecker S, Meier B, Diem P. Efficacy of drug eluting stents in patients with and without diabetes mellitus: indirect comparison of controlled trials. Heart 2006; 92: 650-7.
    • (2006) Heart , vol.92 , pp. 650-657
    • Stettler, C.1    Allemann, S.2    Egger, M.3    Windecker, S.4    Meier, B.5    Diem, P.6
  • 6
    • 33847303686 scopus 로고    scopus 로고
    • Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: A population-based study
    • Lipscombe LL, Hux JE. Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based study. Lancet 2007; 369: 750-6.
    • (2007) Lancet , vol.369 , pp. 750-756
    • Lipscombe, L.L.1    Hux, J.E.2
  • 7
    • 2542504498 scopus 로고    scopus 로고
    • The evolving diabetes burden in the United States
    • Engelgau MM, Geiss LS, Saaddine JB, et al. The evolving diabetes burden in the United States. Ann Intern Med 2004; 140: 945-50.
    • (2004) Ann Intern Med , vol.140 , pp. 945-950
    • Engelgau, M.M.1    Geiss, L.S.2    Saaddine, J.B.3
  • 8
    • 0343209773 scopus 로고    scopus 로고
    • Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators
    • Howard G, O'Leary DH, Zaccaro D, et al. Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Circulation 1996; 93: 1809-17.
    • (1996) Circulation , vol.93 , pp. 1809-1817
    • Howard, G.1    O'Leary, D.H.2    Zaccaro, D.3
  • 9
    • 0242381316 scopus 로고    scopus 로고
    • Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with instent restenosis in patients undergoing coronary stenting
    • Piatti P, Di Mario C, Monti LD, et al. Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with instent restenosis in patients undergoing coronary stenting. Circulation 2003; 108: 2074-81.
    • (2003) Circulation , vol.108 , pp. 2074-2081
    • Piatti, P.1    Di Mario, C.2    Monti, L.D.3
  • 10
    • 1842866397 scopus 로고    scopus 로고
    • Neointimal proliferation within carotid stents is more pronounced in diabetic patients with initial poor glycaemic state
    • Willfort-Ehringer A, Ahmadi R, Gessl A, et al. Neointimal proliferation within carotid stents is more pronounced in diabetic patients with initial poor glycaemic state. Diabetologia 2004; 47: 400-6.
    • (2004) Diabetologia , vol.47 , pp. 400-406
    • Willfort-Ehringer, A.1    Ahmadi, R.2    Gessl, A.3
  • 11
    • 0028069788 scopus 로고
    • NIDDM and its metabolic control predict coronary heart disease in elderly subjects
    • Kuusisto J, Mykkanen L, Pyorala K, Laakso M. NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes 1994; 43: 960-7.
    • (1994) Diabetes , vol.43 , pp. 960-967
    • Kuusisto, J.1    Mykkanen, L.2    Pyorala, K.3    Laakso, M.4
  • 12
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
    • Grundy SM, Brewer HB Jr., Cleeman JI, Smith SC Jr., Lenfant C. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 2004; 109: 433-8.
    • (2004) Circulation , vol.109 , pp. 433-438
    • Grundy, S.M.1    Brewer Jr., H.B.2    Cleeman, J.I.3    Smith Jr., S.C.4    Lenfant, C.5
  • 13
    • 33645978121 scopus 로고    scopus 로고
    • Metabolic syndrome--a new worldwide definition. A Consensus Statement from the International Diabetes Federation
    • Alberti KG, Zimmet P, Shaw J. Metabolic syndrome--a new worldwide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med 2006; 23: 469-80.
    • (2006) Diabet Med , vol.23 , pp. 469-480
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 14
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-5.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3
  • 16
    • 76949084668 scopus 로고    scopus 로고
    • Comparison of four definitions of the metabolic syndrome in a Greek (Mediterranean) population
    • Athyros VG, Ganotakis ES, Tziomalos K, et al. Comparison of four definitions of the metabolic syndrome in a Greek (Mediterranean) population. Curr Med Res Opin 2010; 26: 713-9.
    • (2010) Curr Med Res Opin , vol.26 , pp. 713-719
    • Athyros, V.G.1    Ganotakis, E.S.2    Tziomalos, K.3
  • 17
    • 0037153158 scopus 로고    scopus 로고
    • A central role for JNK in obesity and insulin resistance
    • Hirosumi J, Tuncman G, Chang L, et al. A central role for JNK in obesity and insulin resistance. Nature 2002; 420: 333-6.
    • (2002) Nature , vol.420 , pp. 333-336
    • Hirosumi, J.1    Tuncman, G.2    Chang, L.3
  • 18
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 1996; 271: 665-8.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 19
    • 0346880505 scopus 로고    scopus 로고
    • Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity-and diet-induced insulin resistance
    • Shoelson SE, Lee J, Yuan M. Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity-and diet-induced insulin resistance. Int J Obes Relat Metab Disord 2003; 27(Suppl 3): S49-S52.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.SUPPL. 3
    • Shoelson, S.E.1    Lee, J.2    Yuan, M.3
  • 21
    • 33645304589 scopus 로고    scopus 로고
    • Insulin resistance, the insulin resistance syndrome, and cardiovascular disease
    • Reaven GM. Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. Panminerva Med 2005; 47: 201-10.
    • (2005) Panminerva Med , vol.47 , pp. 201-210
    • Reaven, G.M.1
  • 23
    • 24144484876 scopus 로고    scopus 로고
    • The metabolic syndrome: Time for a critical appraisal: Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes
    • Kahn R, Buse J, Ferrannini E, Stern M. The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2005; 28: 2289-304.
    • (2005) Diabetes Care , vol.28 , pp. 2289-2304
    • Kahn, R.1    Buse, J.2    Ferrannini, E.3    Stern, M.4
  • 24
    • 33845971890 scopus 로고    scopus 로고
    • The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes
    • Lorenzo C, Williams K, Hunt KJ, Haffner SM. The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes. Diabetes Care 2007; 30: 8-13.
    • (2007) Diabetes Care , vol.30 , pp. 8-13
    • Lorenzo, C.1    Williams, K.2    Hunt, K.J.3    Haffner, S.M.4
  • 25
    • 33947305997 scopus 로고    scopus 로고
    • Ten-year risk of cardiovascular incidence related to diabetes, prediabetes, and the metabolic syndrome
    • Liu J, Grundy SM, Wang W, et al. Ten-year risk of cardiovascular incidence related to diabetes, prediabetes, and the metabolic syndrome. Am Heart J 2007; 153: 552-8.
    • (2007) Am Heart J , vol.153 , pp. 552-558
    • Liu, J.1    Grundy, S.M.2    Wang, W.3
  • 26
    • 34249885585 scopus 로고    scopus 로고
    • Relationship between metabolic risk factor clustering and cardiovascular mortality stratified by high blood glucose and obesity: NIPPON DATA90, 1990-2000
    • Kadota A, Hozawa A, Okamura T, et al. Relationship between metabolic risk factor clustering and cardiovascular mortality stratified by high blood glucose and obesity: NIPPON DATA90, 1990-2000. Diabetes Care 2007; 30: 1533-8.
    • (2007) Diabetes Care , vol.30 , pp. 1533-1538
    • Kadota, A.1    Hozawa, A.2    Okamura, T.3
  • 27
    • 33846931618 scopus 로고    scopus 로고
    • Proinflammatory effects of glucose and anti-inflammatory effect of insulin: Relevance to cardiovascular disease
    • Dandona P, Chaudhuri A, Ghanim H, Mohanty P. Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease. Am J Cardiol 2007; 99: 15B-26B.
    • (2007) Am J Cardiol , vol.99
    • Dandona, P.1    Chaudhuri, A.2    Ghanim, H.3    Mohanty, P.4
  • 28
    • 0037177142 scopus 로고    scopus 로고
    • Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
    • Gao F, Gao E, Yue TL, et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation 2002; 105: 1497-502.
    • (2002) Circulation , vol.105 , pp. 1497-1502
    • Gao, F.1    Gao, E.2    Yue, T.L.3
  • 29
    • 0032564373 scopus 로고    scopus 로고
    • Metabolic modulation of acute myocardial infarction
    • The ECLA (Estudios Cardiologicos Latinoamerica) Collaborative Group
    • Diaz R, Paolasso EA, Piegas LS, et al. Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiologicos Latinoamerica) Collaborative Group. Circulation 1998; 98: 2227-34.
    • (1998) Circulation , vol.98 , pp. 2227-2234
    • Diaz, R.1    Paolasso, E.A.2    Piegas, L.S.3
  • 30
    • 0029069020 scopus 로고
    • Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): Effects on mortality at 1 year
    • Malmberg K, Ryden L, Efendic S, et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol 1995; 26: 57-65.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 57-65
    • Malmberg, K.1    Ryden, L.2    Efendic, S.3
  • 31
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in the critically ill patients
    • van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345: 1359-67.
    • (2001) N Engl J Med , vol.345 , pp. 1359-1367
    • van den Berghe, G.1    Wouters, P.2    Weekers, F.3
  • 32
    • 20244384563 scopus 로고    scopus 로고
    • Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): Effects on mortality and morbidity
    • Malmberg K, Ryden L, Wedel H, et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J 2005; 26: 650-61.
    • (2005) Eur Heart J , vol.26 , pp. 650-661
    • Malmberg, K.1    Ryden, L.2    Wedel, H.3
  • 33
    • 36549055740 scopus 로고    scopus 로고
    • Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction
    • Diaz R, Goyal A, Mehta SR, et al. Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. JAMA 2007; 298: 2399-405.
    • (2007) JAMA , vol.298 , pp. 2399-2405
    • Diaz, R.1    Goyal, A.2    Mehta, S.R.3
  • 34
    • 77958182585 scopus 로고    scopus 로고
    • Proinflammatory and prothrombotic effects of hypoglycemia
    • Dandona P, Chaudhuri A, Dhindsa S. Proinflammatory and prothrombotic effects of hypoglycemia. Diabetes Care 2010; 33: 1686-7.
    • (2010) Diabetes Care , vol.33 , pp. 1686-1687
    • Dandona, P.1    Chaudhuri, A.2    Dhindsa, S.3
  • 35
    • 34249692447 scopus 로고    scopus 로고
    • Effect of hyperglycemia and insulin in acute coronary syndromes
    • Dandona P, Chaudhuri A, Ghanim H, Mohanty P. Effect of hyperglycemia and insulin in acute coronary syndromes. Am J Cardiol 2007; 99: 12-18H.
    • (2007) Am J Cardiol , vol.99
    • Dandona, P.1    Chaudhuri, A.2    Ghanim, H.3    Mohanty, P.4
  • 36
    • 0019510754 scopus 로고
    • Effect of insulin on growth of cultured human arterial smooth muscle cells
    • Pfeifle B, Ditschuneit H. Effect of insulin on growth of cultured human arterial smooth muscle cells. Diabetologia 1981; 20: 155-8.
    • (1981) Diabetologia , vol.20 , pp. 155-158
    • Pfeifle, B.1    Ditschuneit, H.2
  • 37
    • 0016605726 scopus 로고
    • Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells
    • Stout RW, Bierman EL, Ross R. Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells. Circ Res 1975; 36: 319-27.
    • (1975) Circ Res , vol.36 , pp. 319-327
    • Stout, R.W.1    Bierman, E.L.2    Ross, R.3
  • 38
    • 0022002617 scopus 로고
    • Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta
    • King GL, Goodman AD, Buzney S, Moses A, Kahn CR. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. J Clin Invest 1985; 75: 1028-36.
    • (1985) J Clin Invest , vol.75 , pp. 1028-1036
    • King, G.L.1    Goodman, A.D.2    Buzney, S.3    Moses, A.4    Kahn, C.R.5
  • 39
    • 0031894221 scopus 로고    scopus 로고
    • Proliferative effect of insulin on cultured smooth muscle cells from rat mesenteric resistance vessels
    • Cruzado M, Risler N, Castro C, Ortiz A, Ruttler ME. Proliferative effect of insulin on cultured smooth muscle cells from rat mesenteric resistance vessels. Am J Hypertens 1998; 11: 54-8.
    • (1998) Am J Hypertens , vol.11 , pp. 54-58
    • Cruzado, M.1    Risler, N.2    Castro, C.3    Ortiz, A.4    Ruttler, M.E.5
  • 40
    • 0024324095 scopus 로고
    • Insulin, insulin-like growth factor I and platelet-derived growth factor interact additively in the induction of the protooncogene c-myc and cellular proliferation in cultured bovine aortic smooth muscle cells
    • Banskota NK, Taub R, Zellner K, King GL. Insulin, insulin-like growth factor I and platelet-derived growth factor interact additively in the induction of the protooncogene c-myc and cellular proliferation in cultured bovine aortic smooth muscle cells. Mol Endocrinol 1989; 3: 1183-90.
    • (1989) Mol Endocrinol , vol.3 , pp. 1183-1190
    • Banskota, N.K.1    Taub, R.2    Zellner, K.3    King, G.L.4
  • 42
    • 0030777901 scopus 로고    scopus 로고
    • Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells
    • Xi XP, Graf K, Goetze S, Hsueh WA, Law RE. Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells. FEBS Lett 1997; 417: 283-6.
    • (1997) FEBS Lett , vol.417 , pp. 283-286
    • Xi, X.P.1    Graf, K.2    Goetze, S.3    Hsueh, W.A.4    Law, R.E.5
  • 43
    • 0033972216 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for insulin-like growth factor-I-induced vascular smooth muscle cell proliferation and migration
    • Duan C, Bauchat JR, Hsieh T. Phosphatidylinositol 3-kinase is required for insulin-like growth factor-I-induced vascular smooth muscle cell proliferation and migration. Circ Res 2000; 86: 15-23.
    • (2000) Circ Res , vol.86 , pp. 15-23
    • Duan, C.1    Bauchat, J.R.2    Hsieh, T.3
  • 44
    • 17744373075 scopus 로고    scopus 로고
    • Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia
    • Draznin B, Miles P, Kruszynska Y, et al. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology 2000; 141: 1310-6.
    • (2000) Endocrinology , vol.141 , pp. 1310-1316
    • Draznin, B.1    Miles, P.2    Kruszynska, Y.3
  • 45
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV, et al. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000; 101: 1539-45.
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3
  • 47
    • 0034651949 scopus 로고    scopus 로고
    • Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin
    • Kuboki K, Jiang ZY, Takahara N, et al. Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation 2000; 101: 676-81.
    • (2000) Circulation , vol.101 , pp. 676-681
    • Kuboki, K.1    Jiang, Z.Y.2    Takahara, N.3
  • 48
    • 23744493885 scopus 로고    scopus 로고
    • Mathematical modeling of the nitric oxide/cGMP pathway in the vascular smooth muscle cell
    • Yang J, Clark JW, Bryan RM, Robertson CS. Mathematical modeling of the nitric oxide/cGMP pathway in the vascular smooth muscle cell. Am J Physiol Heart Circ Physiol 2005; 289: H886-H897.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Yang, J.1    Clark, J.W.2    Bryan, R.M.3    Robertson, C.S.4
  • 49
    • 0030936601 scopus 로고    scopus 로고
    • Dual cell cyclespecific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells
    • Sarkar R, Gordon D, Stanley JC, Webb RC. Dual cell cyclespecific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells. J Hypertens 1997; 15: 275-83.
    • (1997) J Hypertens , vol.15 , pp. 275-283
    • Sarkar, R.1    Gordon, D.2    Stanley, J.C.3    Webb, R.C.4
  • 50
    • 0032589074 scopus 로고    scopus 로고
    • alpha1-Adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: Role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase
    • Hu ZW, Shi XY, Lin RZ, Chen J, Hoffman BB. alpha1-Adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase. J Pharmacol Exp Ther 1999; 290: 28-37.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 28-37
    • Hu, Z.W.1    Shi, X.Y.2    Lin, R.Z.3    Chen, J.4    Hoffman, B.B.5
  • 51
    • 0032566624 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinase phosphatase-1 induction by insulin in vascular smooth muscle cells. Evaluation of the role of the nitric oxide signaling pathway and potential defects in hypertension
    • Begum N, Ragolia L, Rienzie J, McCarthy M, Duddy N. Regulation of mitogen-activated protein kinase phosphatase-1 induction by insulin in vascular smooth muscle cells. Evaluation of the role of the nitric oxide signaling pathway and potential defects in hypertension. J Biol Chem 1998; 273: 25164-70.
    • (1998) J Biol Chem , vol.273 , pp. 25164-25170
    • Begum, N.1    Ragolia, L.2    Rienzie, J.3    McCarthy, M.4    Duddy, N.5
  • 52
    • 0028330152 scopus 로고
    • Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation
    • Bornfeldt KE, Raines EW, Nakano T, Graves LM, Krebs EG, Ross R. Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J Clin Invest 1994; 93: 1266-74.
    • (1994) J Clin Invest , vol.93 , pp. 1266-1274
    • Bornfeldt, K.E.1    Raines, E.W.2    Nakano, T.3    Graves, L.M.4    Krebs, E.G.5    Ross, R.6
  • 53
    • 0033065928 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB (PDGF-BB) regulation of migration and focal adhesion kinase phosphorylation in rabbit aortic vascular smooth muscle cells: Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinases
    • Cospedal R, Abedi H, Zachary I. Platelet-derived growth factor-BB (PDGF-BB) regulation of migration and focal adhesion kinase phosphorylation in rabbit aortic vascular smooth muscle cells: roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinases. Cardiovasc Res 1999; 41: 708-21.
    • (1999) Cardiovasc Res , vol.41 , pp. 708-721
    • Cospedal, R.1    Abedi, H.2    Zachary, I.3
  • 54
    • 0033304619 scopus 로고    scopus 로고
    • Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascu lar smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I
    • Imai Y, Clemmons DR. Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascu lar smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I. Endocrinology 1999; 140: 4228-35.
    • (1999) Endocrinology , vol.140 , pp. 4228-4235
    • Imai, Y.1    Clemmons, D.R.2
  • 55
    • 0032213801 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle migration by mitogenactivated protein kinase and calcium/calmodulin-dependent protein kinase II signaling pathways
    • Lundberg MS, Curto KA, Bilato C, Monticone RE, Crow MT. Regulation of vascular smooth muscle migration by mitogenactivated protein kinase and calcium/calmodulin-dependent protein kinase II signaling pathways. J Mol Cell Cardiol 1998; 30: 2377-89.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 2377-2389
    • Lundberg, M.S.1    Curto, K.A.2    Bilato, C.3    Monticone, R.E.4    Crow, M.T.5
  • 56
    • 0029125685 scopus 로고
    • Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II
    • Gockerman A, Prevette T, Jones JI, Clemmons DR. Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II. Endocrinology 1995; 136: 4168-73.
    • (1995) Endocrinology , vol.136 , pp. 4168-4173
    • Gockerman, A.1    Prevette, T.2    Jones, J.I.3    Clemmons, D.R.4
  • 57
  • 58
    • 0033977725 scopus 로고    scopus 로고
    • Insulin inhibits migration of vascular smooth muscle cells with inducible nitric oxide synthase
    • Kahn AM, Allen JC, Seidel CL, Zhang S. Insulin inhibits migration of vascular smooth muscle cells with inducible nitric oxide synthase. Hypertension 2000; 35: 303-6.
    • (2000) Hypertension , vol.35 , pp. 303-306
    • Kahn, A.M.1    Allen, J.C.2    Seidel, C.L.3    Zhang, S.4
  • 59
    • 0021956761 scopus 로고
    • Stimulatory effect of insulin on aortic smooth muscle cell migration induced by 12-Lhydroxy-5,8,10,14-eicosatetraenoic acid and its modulation by elevated extracellular glucose levels
    • Nakao J, Ito H, Kanayasu T, Murota S. Stimulatory effect of insulin on aortic smooth muscle cell migration induced by 12-Lhydroxy-5,8,10,14-eicosatetraenoic acid and its modulation by elevated extracellular glucose levels. Diabetes 1985; 34: 185-91.
    • (1985) Diabetes , vol.34 , pp. 185-191
    • Nakao, J.1    Ito, H.2    Kanayasu, T.3    Murota, S.4
  • 60
    • 0037465793 scopus 로고    scopus 로고
    • Insulinstimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulindependent protein kinase II
    • Zhang S, Yang Y, Kone BC, Allen JC, Kahn AM. Insulinstimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulindependent protein kinase II. Circulation 2003; 107: 1539-44.
    • (2003) Circulation , vol.107 , pp. 1539-1544
    • Zhang, S.1    Yang, Y.2    Kone, B.C.3    Allen, J.C.4    Kahn, A.M.5
  • 61
    • 0036720934 scopus 로고    scopus 로고
    • Insulin inhibits PDGF-directed VSMC migration via NO/ cGMP increase of MKP-1 and its inactivation of MAPKs
    • Jacob A, Molkentin JD, Smolenski A, Lohmann SM, Begum N. Insulin inhibits PDGF-directed VSMC migration via NO/ cGMP increase of MKP-1 and its inactivation of MAPKs. Am J Physiol Cell Physiol 2002; 283: C704-C713.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Jacob, A.1    Molkentin, J.D.2    Smolenski, A.3    Lohmann, S.M.4    Begum, N.5
  • 62
    • 0033014071 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in human coronary atherosclerotic plaque
    • Depre C, Havaux X, Renkin J, Vanoverschelde JL, Wijns W. Expression of inducible nitric oxide synthase in human coronary atherosclerotic plaque. Cardiovasc Res 1999; 41: 465-72.
    • (1999) Cardiovasc Res , vol.41 , pp. 465-472
    • Depre, C.1    Havaux, X.2    Renkin, J.3    Vanoverschelde, J.L.4    Wijns, W.5
  • 63
    • 0344193130 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase after endothelial denudation of the rat carotid artery: Role of platelets
    • Gonzalez-Fernandez F, Lopez-Farre A, Rodriguez-Feo JA, et al. Expression of inducible nitric oxide synthase after endothelial denudation of the rat carotid artery: role of platelets. Circ Res 1998; 83: 1080-7.
    • (1998) Circ Res , vol.83 , pp. 1080-1087
    • Gonzalez-Fernandez, F.1    Lopez-Farre, A.2    Rodriguez-Feo, J.A.3
  • 64
    • 0031906154 scopus 로고    scopus 로고
    • Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells
    • Yan Z, Hansson GK. Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells. Circ Res 1998; 82: 21-9.
    • (1998) Circ Res , vol.82 , pp. 21-29
    • Yan, Z.1    Hansson, G.K.2
  • 65
    • 0141866848 scopus 로고    scopus 로고
    • Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways
    • Wang CC, Gurevich I, Draznin B. Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes 2003; 52: 2562-9.
    • (2003) Diabetes , vol.52 , pp. 2562-2569
    • Wang, C.C.1    Gurevich, I.2    Draznin, B.3
  • 66
    • 0344844386 scopus 로고    scopus 로고
    • Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix metalloproteinase-9
    • Dandona P, Aljada A, Mohanty P, Ghanim H, Bandyopadhyay A, Chaudhuri A. Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix metalloproteinase-9. Diabetes Care 2003; 26: 3310-4.
    • (2003) Diabetes Care , vol.26 , pp. 3310-3314
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Bandyopadhyay, A.5    Chaudhuri, A.6
  • 67
    • 27344448935 scopus 로고    scopus 로고
    • Insulin resistance is associated to increased MMP-2 expression in vascular cells through a PI-3 kinase dependent mechanism
    • Federici M, Menghini R, Hribal ML, et al. Insulin resistance is associated to increased MMP-2 expression in vascular cells through a PI-3 kinase dependent mechanism. Diabetes 2001; 50 (Suppl 2): A153.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Federici, M.1    Menghini, R.2    Hribal, M.L.3
  • 68
    • 0030064282 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury
    • Bendeck MP, Irvin C, Reidy MA. Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury. Circ Res 1996; 78: 38-43.
    • (1996) Circ Res , vol.78 , pp. 38-43
    • Bendeck, M.P.1    Irvin, C.2    Reidy, M.A.3
  • 69
    • 0028146228 scopus 로고
    • Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat
    • Bendeck MP, Zempo N, Clowes AW, Galardy RE, Reidy MA. Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. Circ Res 1994; 75: 539-45.
    • (1994) Circ Res , vol.75 , pp. 539-545
    • Bendeck, M.P.1    Zempo, N.2    Clowes, A.W.3    Galardy, R.E.4    Reidy, M.A.5
  • 70
    • 0033387969 scopus 로고    scopus 로고
    • eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity
    • Gurjar MV, Sharma RV, Bhalla RC. eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity. Arterioscler Thromb Vasc Biol 1999; 19: 2871-7.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2871-2877
    • Gurjar, M.V.1    Sharma, R.V.2    Bhalla, R.C.3
  • 71
    • 9144273829 scopus 로고    scopus 로고
    • Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factorkappaB and activator protein-1 activity
    • Knipp BS, Ailawadi G, Ford JW, et al. Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factorkappaB and activator protein-1 activity. J Surg Res 2004; 116: 70-80.
    • (2004) J Surg Res , vol.116 , pp. 70-80
    • Knipp, B.S.1    Ailawadi, G.2    Ford, J.W.3
  • 72
    • 0034869547 scopus 로고    scopus 로고
    • Mechanism of inhibition of matrix metalloproteinase-9 induction by NO in vascular smooth muscle cells
    • Gurjar MV, Deleon J, Sharma RV, Bhalla RC. Mechanism of inhibition of matrix metalloproteinase-9 induction by NO in vascular smooth muscle cells. J Appl Physiol 2001; 91: 1380-6.
    • (2001) J Appl Physiol , vol.91 , pp. 1380-1386
    • Gurjar, M.V.1    Deleon, J.2    Sharma, R.V.3    Bhalla, R.C.4
  • 73
    • 0035406154 scopus 로고    scopus 로고
    • Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro
    • Upchurch GR, Jr., Ford JW, Weiss SJ, et al. Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro. J Vasc Surg 2001; 34: 76-83.
    • (2001) J Vasc Surg , vol.34 , pp. 76-83
    • Upchurch Jr., G.R.1    Ford, J.W.2    Weiss, S.J.3
  • 74
    • 0141742351 scopus 로고    scopus 로고
    • Nitric oxide and cyclic GMP increase the expression of matrix metalloproteinase-9 in vascular smooth muscle
    • Marcet-Palacios M, Graham K, Cass C, Befus AD, Mayers I, Radomski MW. Nitric oxide and cyclic GMP increase the expression of matrix metalloproteinase-9 in vascular smooth muscle. J Pharmacol Exp Ther 2003; 307: 429-36.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 429-436
    • Marcet-Palacios, M.1    Graham, K.2    Cass, C.3    Befus, A.D.4    Mayers, I.5    Radomski, M.W.6
  • 75
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 76
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340: 115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 77
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 78
    • 0034721766 scopus 로고    scopus 로고
    • Hyperinsulinemia and vascular dysfunction: The role of nuclear factor-kappaB, yet again
    • Schmidt AM, Stern DM. Hyperinsulinemia and vascular dysfunction: the role of nuclear factor-kappaB, yet again. Circ Res 2000; 87: 722-4.
    • (2000) Circ Res , vol.87 , pp. 722-724
    • Schmidt, A.M.1    Stern, D.M.2
  • 79
    • 0034456622 scopus 로고    scopus 로고
    • Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide
    • Aljada A, Saadeh R, Assian E, Ghanim H, Dandona P. Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide. J Clin Endocrinol Metab 2000; 85: 2572-5.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2572-2575
    • Aljada, A.1    Saadeh, R.2    Assian, E.3    Ghanim, H.4    Dandona, P.5
  • 80
    • 0034746443 scopus 로고    scopus 로고
    • Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells
    • Aljada A, Ghanim H, Saadeh R, Dandona P. Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells. J Clin Endocrinol Metab 2001; 86: 450-3.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 450-453
    • Aljada, A.1    Ghanim, H.2    Saadeh, R.3    Dandona, P.4
  • 81
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferatoractivated receptor gamma activity by mitogen-activated protein kinase
    • Camp HS, Tafuri SR. Regulation of peroxisome proliferatoractivated receptor gamma activity by mitogen-activated protein kinase. J Biol Chem 1997; 272: 10811-6.
    • (1997) J Biol Chem , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 82
    • 0034721925 scopus 로고    scopus 로고
    • Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells
    • Golovchenko I, Goalstone ML, Watson P, Brownlee M, Draznin B. Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells. Circ Res 2000; 87: 746-52.
    • (2000) Circ Res , vol.87 , pp. 746-752
    • Golovchenko, I.1    Goalstone, M.L.2    Watson, P.3    Brownlee, M.4    Draznin, B.5
  • 83
    • 0035061658 scopus 로고    scopus 로고
    • Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury
    • Pluta RM, Rak R, Wink DA, Woodward JJ, Khaldi A, Oldfield EH, Watson JC. Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury. Neurosurgery 2001; 48: 884-92.
    • (2001) Neurosurgery , vol.48 , pp. 884-892
    • Pluta, R.M.1    Rak, R.2    Wink, D.A.3    Woodward, J.J.4    Khaldi, A.5    Oldfield, E.H.6    Watson, J.C.7
  • 84
    • 0035887540 scopus 로고    scopus 로고
    • Insulin enhances platelet activation in vitro
    • Yngen M, Li N, Hjemdahl P, Wallen NH. Insulin enhances platelet activation in vitro. Thromb Res 2001; 104: 85-91.
    • (2001) Thromb Res , vol.104 , pp. 85-91
    • Yngen, M.1    Li, N.2    Hjemdahl, P.3    Wallen, N.H.4
  • 85
    • 0029866631 scopus 로고    scopus 로고
    • Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations
    • Anfossi G, Massucco P, Mattiello L, et al. Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations. Thromb Res 1996; 82: 57-68.
    • (1996) Thromb Res , vol.82 , pp. 57-68
    • Anfossi, G.1    Massucco, P.2    Mattiello, L.3
  • 86
    • 0031838104 scopus 로고    scopus 로고
    • Insulin, insulin resistance and platelet function: Similarities with insulin effects on cultured vascular smooth muscle cells
    • Trovati M, Anfossi G. Insulin, insulin resistance and platelet function: similarities with insulin effects on cultured vascular smooth muscle cells. Diabetologia 1998; 41: 609-22.
    • (1998) Diabetologia , vol.41 , pp. 609-622
    • Trovati, M.1    Anfossi, G.2
  • 87
    • 0023277526 scopus 로고
    • Reduction of platelet aggregation induced by euglycaemic insulin clamp
    • Hiramatsu K, Nozaki H, Arimori S. Reduction of platelet aggregation induced by euglycaemic insulin clamp. Diabetologia 1987; 30: 310-3.
    • (1987) Diabetologia , vol.30 , pp. 310-313
    • Hiramatsu, K.1    Nozaki, H.2    Arimori, S.3
  • 88
    • 0027136514 scopus 로고
    • Inhibition of platelet aggregation and the stimulation of prostacyclin synthesis by insulin in humans
    • Kahn NN, Bauman WA, Hatcher VB, Sinha AK. Inhibition of platelet aggregation and the stimulation of prostacyclin synthesis by insulin in humans. Am J Physiol 1993; 265: H2160-H2167.
    • (1993) Am J Physiol , vol.265
    • Kahn, N.N.1    Bauman, W.A.2    Hatcher, V.B.3    Sinha, A.K.4
  • 89
    • 0024213166 scopus 로고
    • Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo
    • Trovati M, Anfossi G, Cavalot F, Massucco P, Mularoni E, Emanuelli G. Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo. Diabetes 1988; 37: 780-6.
    • (1988) Diabetes , vol.37 , pp. 780-786
    • Trovati, M.1    Anfossi, G.2    Cavalot, F.3    Massucco, P.4    Mularoni, E.5    Emanuelli, G.6
  • 90
    • 0036144715 scopus 로고    scopus 로고
    • Inhibition of platelet-collagen interaction: An in vivo action of insulin abolished by insulin resistance in obesity
    • Westerbacka J, Yki-Jarvinen H, Turpeinen A, et al. Inhibition of platelet-collagen interaction: an in vivo action of insulin abolished by insulin resistance in obesity. Arterioscler Thromb Vasc Biol 2002; 22: 167-72.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 167-172
    • Westerbacka, J.1    Yki-Jarvinen, H.2    Turpeinen, A.3
  • 91
    • 2942530422 scopus 로고    scopus 로고
    • Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription
    • Vulin AI, Stanley FM. Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription. J Biol Chem 2004; 279: 25172-8.
    • (2004) J Biol Chem , vol.279 , pp. 25172-25178
    • Vulin, A.I.1    Stanley, F.M.2
  • 92
    • 0036964978 scopus 로고    scopus 로고
    • Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations
    • Aljada A, Ghanim H, Mohanty P, Kapur N, Dandona P. Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J Clin Endocrinol Metab 2002; 87: 1419-22.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1419-1422
    • Aljada, A.1    Ghanim, H.2    Mohanty, P.3    Kapur, N.4    Dandona, P.5
  • 93
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P, Aljada A, Mohanty P, et al. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 2001; 86: 3257-65.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3
  • 94
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 95
    • 0028836794 scopus 로고
    • Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases
    • Galis ZS, Sukhova GK, Kranzhofer R, Clark S, Libby P. Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci USA 1995; 92: 402-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 402-406
    • Galis, Z.S.1    Sukhova, G.K.2    Kranzhofer, R.3    Clark, S.4    Libby, P.5
  • 96
    • 0021244574 scopus 로고
    • Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death
    • Davies MJ, Thomas A. Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death. N Engl J Med 1984; 310: 1137-40.
    • (1984) N Engl J Med , vol.310 , pp. 1137-1140
    • Davies, M.J.1    Thomas, A.2
  • 98
    • 0033867723 scopus 로고    scopus 로고
    • Plasma insulin and all-cause, cardiovascular, and noncardiovascular mortality: The 22-year follow-up results of the Helsinki Policemen Study
    • Pyorala M, Miettinen H, Laakso M, Pyorala K. Plasma insulin and all-cause, cardiovascular, and noncardiovascular mortality: the 22-year follow-up results of the Helsinki Policemen Study. Diabetes Care 2000; 23: 1097-102.
    • (2000) Diabetes Care , vol.23 , pp. 1097-1102
    • Pyorala, M.1    Miettinen, H.2    Laakso, M.3    Pyorala, K.4
  • 99
    • 0027974879 scopus 로고
    • Insulin in ischaemic heart disease: Are associations explained by triglyceride concentrations? The Caerphilly prospective study
    • Yarnell JW, Sweetnam PM, Marks V, Teale JD, Bolton CH. Insulin in ischaemic heart disease: are associations explained by triglyceride concentrations? The Caerphilly prospective study. Br Heart J 1994; 71: 293-6.
    • (1994) Br Heart J , vol.71 , pp. 293-296
    • Yarnell, J.W.1    Sweetnam, P.M.2    Marks, V.3    Teale, J.D.4    Bolton, C.H.5
  • 100
    • 0030907355 scopus 로고    scopus 로고
    • Hyperinsulinemia in patients with coronary heart disease in absence of overt risk factors
    • Ariza CR, Frati AC, Gomez G, Almazan A. Hyperinsulinemia in patients with coronary heart disease in absence of overt risk factors. Arch Med Res 1997; 28: 115-9.
    • (1997) Arch Med Res , vol.28 , pp. 115-119
    • Ariza, C.R.1    Frati, A.C.2    Gomez, G.3    Almazan, A.4
  • 101
    • 0030028633 scopus 로고    scopus 로고
    • Role of insulin resistance associated with compensatory hyperinsulinemia in ischemic stroke
    • Shinozaki K, Naritomi H, Shimizu T, et al. Role of insulin resistance associated with compensatory hyperinsulinemia in ischemic stroke. Stroke 1996; 27: 37-43.
    • (1996) Stroke , vol.27 , pp. 37-43
    • Shinozaki, K.1    Naritomi, H.2    Shimizu, T.3
  • 102
    • 0030057686 scopus 로고    scopus 로고
    • Demonstration of insulin resistance in coronary artery disease documented with angiography
    • Shinozaki K, Suzuki M, Ikebuchi M, Hara Y, Harano Y. Demonstration of insulin resistance in coronary artery disease documented with angiography. Diabetes Care 1996; 19: 1-7.
    • (1996) Diabetes Care , vol.19 , pp. 1-7
    • Shinozaki, K.1    Suzuki, M.2    Ikebuchi, M.3    Hara, Y.4    Harano, Y.5
  • 103
    • 0029061911 scopus 로고
    • Carotid artery wall intima-media thickness is associated with insulin-mediated glucose disposal in men at high and low coronary risk
    • Agewall S, Fagerberg B, Attvall S, Wendelhag I, Urbanavicius V, Wikstrand J. Carotid artery wall intima-media thickness is associated with insulin-mediated glucose disposal in men at high and low coronary risk. Stroke 1995; 26: 956-60.
    • (1995) Stroke , vol.26 , pp. 956-960
    • Agewall, S.1    Fagerberg, B.2    Attvall, S.3    Wendelhag, I.4    Urbanavicius, V.5    Wikstrand, J.6
  • 104
    • 0025915745 scopus 로고
    • Asymptomatic atherosclerosis and insulin resistance
    • Laakso M, Sarlund H, Salonen R, et al. Asymptomatic atherosclerosis and insulin resistance. Arterioscler Thromb 1991; 11: 1068-76.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1068-1076
    • Laakso, M.1    Sarlund, H.2    Salonen, R.3
  • 105
    • 29144453326 scopus 로고    scopus 로고
    • Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
    • Nathan DM, Cleary PA, Backlund JY, et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005; 353: 2643-53.
    • (2005) N Engl J Med , vol.353 , pp. 2643-2653
    • Nathan, D.M.1    Cleary, P.A.2    Backlund, J.Y.3
  • 106
    • 33745794471 scopus 로고    scopus 로고
    • Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: A prospective observational study (UKPDS 75)
    • Stratton IM, Cull CA, Adler AI, Matthews DR, Neil HA, Holman RR. Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: a prospective observational study (UKPDS 75). Diabetologia 2006; 49: 1761-9.
    • (2006) Diabetologia , vol.49 , pp. 1761-1769
    • Stratton, I.M.1    Cull, C.A.2    Adler, A.I.3    Matthews, D.R.4    Neil, H.A.5    Holman, R.R.6
  • 107
    • 45149131667 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in type 2 diabetes
    • Gerstein HC, Miller ME, Byington RP, et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008; 358: 2545-59.
    • (2008) N Engl J Med , vol.358 , pp. 2545-2559
    • Gerstein, H.C.1    Miller, M.E.2    Byington, R.P.3
  • 108
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • Patel A, MacMahon S, Chalmers J, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358: 2560-72.
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
    • Patel, A.1    McMahon, S.2    Chalmers, J.3
  • 109
    • 58149389215 scopus 로고    scopus 로고
    • Glucose control and vascular complications in veterans with type 2 diabetes
    • Duckworth W, Abraira C, Moritz T, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360: 129-39.
    • (2009) N Engl J Med , vol.360 , pp. 129-139
    • Duckworth, W.1    Abraira, C.2    Moritz, T.3
  • 110
    • 74949117631 scopus 로고    scopus 로고
    • The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: Retrospective epidemiological analysis of the ACCORD study
    • Bonds DE, Miller ME, Bergenstal RM, et al. The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study. BMJ 2010; 340: b4909.
    • (2010) BMJ , vol.340
    • Bonds, D.E.1    Miller, M.E.2    Bergenstal, R.M.3
  • 111
    • 77950511412 scopus 로고    scopus 로고
    • Executive summary: Standards of medical care in diabetes--2010
    • Executive summary: Standards of medical care in diabetes--2010. Diabetes Care 2010; 33(Suppl 1): S4-10.
    • (2010) Diabetes Care , vol.33 , Issue.SUPPL. 1
  • 112
    • 67149142042 scopus 로고    scopus 로고
    • A randomized trial of therapies for type 2 diabetes and coronary artery disease
    • Frye RL, August P, Brooks MM, et al. A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med 2009; 360: 2503-15.
    • (2009) N Engl J Med , vol.360 , pp. 2503-2515
    • Frye, R.L.1    August, P.2    Brooks, M.M.3
  • 113
    • 0000514852 scopus 로고
    • The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit
    • Duff GL, Brechin DJ, Finkelstein WE. The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit. J Exp Med 1954; 100: 371-80.
    • (1954) J Exp Med , vol.100 , pp. 371-380
    • Duff, G.L.1    Brechin, D.J.2    Finkelstein, W.E.3
  • 114
    • 0017811360 scopus 로고
    • Effect of insulin in the induction and regression of experimental cholesterol atherosclerosis in the rabbit
    • Marquie G. Effect of insulin in the induction and regression of experimental cholesterol atherosclerosis in the rabbit. Postgrad Med J 1978; 54: 80-5.
    • (1978) Postgrad Med J , vol.54 , pp. 80-85
    • Marquie, G.1
  • 115
    • 0000330734 scopus 로고
    • Effect of insulin in the induction and regression of atherosclerosis in the chick
    • Stamler J, Pick R, Katz LN. Effect of insulin in the induction and regression of atherosclerosis in the chick. Circ Res 1960; 8: 572-6.
    • (1960) Circ Res , vol.8 , pp. 572-576
    • Stamler, J.1    Pick, R.2    Katz, L.N.3
  • 116
    • 0031002083 scopus 로고    scopus 로고
    • Effect of exogenous hyperinsulinaemia on atherogenesis in cholesterol-fed rabbits
    • Nordestgaard BG, Agerholm-Larsen B, Stender S. Effect of exogenous hyperinsulinaemia on atherogenesis in cholesterol-fed rabbits. Diabetologia 1997; 40: 512-20.
    • (1997) Diabetologia , vol.40 , pp. 512-520
    • Nordestgaard, B.G.1    Agerholm-Larsen, B.2    Stender, S.3
  • 117
    • 0037231634 scopus 로고    scopus 로고
    • Oral insulin supplementation attenuates atherosclerosis progression in apolipoprotein E-deficient mice
    • Shamir R, Shehadeh N, Rosenblat M, et al. Oral insulin supplementation attenuates atherosclerosis progression in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2003; 23: 104-10.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 104-110
    • Shamir, R.1    Shehadeh, N.2    Rosenblat, M.3
  • 118
    • 17844383449 scopus 로고    scopus 로고
    • Attenuation of accumulation of neointimal lipid by pioglitazone in mice genetically deficient in insulin receptor substrate-2 and apolipoprotein E
    • Clough MH, Schneider DJ, Sobel BE, White MF, Wadsworth MP, Taatjes DJ. Attenuation of accumulation of neointimal lipid by pioglitazone in mice genetically deficient in insulin receptor substrate-2 and apolipoprotein E. J Histochem Cytochem 2005; 53: 603-10.
    • (2005) J Histochem Cytochem , vol.53 , pp. 603-610
    • Clough, M.H.1    Schneider, D.J.2    Sobel, B.E.3    White, M.F.4    Wadsworth, M.P.5    Taatjes, D.J.6
  • 119
    • 33645563765 scopus 로고    scopus 로고
    • Myeloid lineage cellrestricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
    • Baumgartl J, Baudler S, Scherner M, et al. Myeloid lineage cellrestricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Cell Metab 2006; 3: 247-56.
    • (2006) Cell Metab , vol.3 , pp. 247-256
    • Baumgartl, J.1    Baudler, S.2    Scherner, M.3
  • 120
    • 36048950184 scopus 로고    scopus 로고
    • Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice
    • Gonzalez-Navarro H, Vila-Caballer M, Pastor MF, et al. Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice. Front Biosci 2007; 12: 2291-8.
    • (2007) Front Biosci , vol.12 , pp. 2291-2298
    • Gonzalez-Navarro, H.1    Vila-Caballer, M.2    Pastor, M.F.3
  • 121
    • 57549092036 scopus 로고    scopus 로고
    • Molecular mechanisms of atherosclerosis in metabolic syndrome: Role of reduced IRS2-dependent signaling
    • Gonzalez-Navarro H, Vinue A, Vila-Caballer M, et al. Molecular mechanisms of atherosclerosis in metabolic syndrome: role of reduced IRS2-dependent signaling. Arterioscler Thromb Vasc Biol 2008; 28: 2187-94.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2187-2194
    • Gonzalez-Navarro, H.1    Vinue, A.2    Vila-Caballer, M.3
  • 122
    • 36448943901 scopus 로고    scopus 로고
    • Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease
    • Fernandez-Hernando C, Ackah E, Yu J, et al. Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metab 2007; 6: 446-57.
    • (2007) Cell Metab , vol.6 , pp. 446-457
    • Fernandez-Hernando, C.1    Ackah, E.2    Yu, J.3
  • 123
    • 73849128842 scopus 로고    scopus 로고
    • Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis
    • Fernandez-Hernando C, Jozsef L, Jenkins D, Di LA, Sessa WC. Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis. Arterioscler Thromb Vasc Biol 2009; 29: 2033-40.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 2033-2040
    • Fernandez-Hernando, C.1    Jozsef, L.2    Jenkins, D.3    Di, L.A.4    Sessa, W.C.5
  • 124
    • 0032567937 scopus 로고    scopus 로고
    • Disruption of IRS-2 causes type 2 diabetes in mice
    • Withers DJ, Gutierrez JS, Towery H, et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 1998; 391: 900-4.
    • (1998) Nature , vol.391 , pp. 900-904
    • Withers, D.J.1    Gutierrez, J.S.2    Towery, H.3
  • 125
    • 0033755408 scopus 로고    scopus 로고
    • Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia
    • Kubota N, Tobe K, Terauchi Y, et al. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes 2000; 49: 1880-9.
    • (2000) Diabetes , vol.49 , pp. 1880-1889
    • Kubota, N.1    Tobe, K.2    Terauchi, Y.3
  • 126
    • 33645567816 scopus 로고    scopus 로고
    • Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions
    • Han S, Liang CP, DeVries-Seimon T, et al. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metab 2006; 3: 257-66.
    • (2006) Cell Metab , vol.3 , pp. 257-266
    • Han, S.1    Liang, C.P.2    DeVries-Seimon, T.3
  • 127
    • 77955292064 scopus 로고    scopus 로고
    • Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice
    • Rask-Madsen C, Li Q, Freund B, et al. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab 2010; 11: 379-89.
    • (2010) Cell Metab , vol.11 , pp. 379-389
    • Rask-Madsen, C.1    Li, Q.2    Freund, B.3
  • 128
    • 34250795031 scopus 로고    scopus 로고
    • Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet
    • Harrington SC, Simari RD, Conover CA. Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet. Circ Res 2007; 100: 1696-702.
    • (2007) Circ Res , vol.100 , pp. 1696-1702
    • Harrington, S.C.1    Simari, R.D.2    Conover, C.A.3
  • 129
    • 36349028053 scopus 로고    scopus 로고
    • IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice
    • Sukhanov S, Higashi Y, Shai SY, et al. IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2007; 27: 2684-90.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2684-2690
    • Sukhanov, S.1    Higashi, Y.2    Shai, S.Y.3
  • 130
    • 0037137293 scopus 로고    scopus 로고
    • Coronary bypass graft patency in patients with diabetes in the Bypass Angioplasty Revascularization Investigation (BARI)
    • Schwartz L, Kip KE, Frye RL, Alderman EL, Schaff HV, Detre KM. Coronary bypass graft patency in patients with diabetes in the Bypass Angioplasty Revascularization Investigation (BARI). Circulation 2002; 106: 2652-8.
    • (2002) Circulation , vol.106 , pp. 2652-2658
    • Schwartz, L.1    Kip, K.E.2    Frye, R.L.3    Alderman, E.L.4    Schaff, H.V.5    Detre, K.M.6
  • 131
    • 0032414341 scopus 로고    scopus 로고
    • Restenosis after percutaneous transluminal coronary angioplasty in patients with non-insulindependent diabetes mellitus (NIDDM)
    • Asakura Y, Suzuki M, Nonogi H, et al. Restenosis after percutaneous transluminal coronary angioplasty in patients with non-insulindependent diabetes mellitus (NIDDM). J Cardiovasc Risk 1998; 5: 331-4.
    • (1998) J Cardiovasc Risk , vol.5 , pp. 331-334
    • Asakura, Y.1    Suzuki, M.2    Nonogi, H.3
  • 132
    • 2542453844 scopus 로고    scopus 로고
    • Impact of sirolimus-eluting stents on outcome in diabetic patients: A SIRIUS (SIRolImUScoated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy
    • Moussa I, Leon MB, Baim DS, et al. Impact of sirolimus-eluting stents on outcome in diabetic patients: a SIRIUS (SIRolImUScoated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy. Circulation 2004; 109: 2273-8.
    • (2004) Circulation , vol.109 , pp. 2273-2278
    • Moussa, I.1    Leon, M.B.2    Baim, D.S.3
  • 133
    • 11144357913 scopus 로고    scopus 로고
    • One-year clinical results with the slow-release, polymer-based, paclitaxel-eluting TAXUS stent: The TAXUS-IV trial
    • Stone GW, Ellis SG, Cox DA, et al. One-year clinical results with the slow-release, polymer-based, paclitaxel-eluting TAXUS stent: the TAXUS-IV trial. Circulation 2004; 109: 1942-7.
    • (2004) Circulation , vol.109 , pp. 1942-1947
    • Stone, G.W.1    Ellis, S.G.2    Cox, D.A.3
  • 134
    • 0032521534 scopus 로고    scopus 로고
    • Usefulness of enhanced insulin secretion during an oral glucose tolerance test as a predictor of restenosis after direct percutaneous transluminal coronary angioplasty during acute myocardial infarction in patients without diabetes mellitus
    • Osanai H, Kanayama H, Miyazaki Y, Fukushima A, Shinoda M, Ito T. Usefulness of enhanced insulin secretion during an oral glucose tolerance test as a predictor of restenosis after direct percutaneous transluminal coronary angioplasty during acute myocardial infarction in patients without diabetes mellitus. Am J Cardiol 1998; 81: 698-701.
    • (1998) Am J Cardiol , vol.81 , pp. 698-701
    • Osanai, H.1    Kanayama, H.2    Miyazaki, Y.3    Fukushima, A.4    Shinoda, M.5    Ito, T.6
  • 136
    • 0033851375 scopus 로고    scopus 로고
    • Hyperinsulinemia during oral glucose tolerance test is associated with increased neointimal tissue proliferation after coronary stent implantation in nondiabetic patients: A serial intravascular ultrasound study
    • Takagi T, Yoshida K, Akasaka T, et al. Hyperinsulinemia during oral glucose tolerance test is associated with increased neointimal tissue proliferation after coronary stent implantation in nondiabetic patients: a serial intravascular ultrasound study. J Am Coll Cardiol 2000; 36: 731-8.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 731-738
    • Takagi, T.1    Yoshida, K.2    Akasaka, T.3
  • 137
    • 0034057386 scopus 로고    scopus 로고
    • The mechanisms of coronary restenosis: Insights from experimental models
    • Ferns GA, Avades TY. The mechanisms of coronary restenosis: insights from experimental models. Int J Exp Pathol 2000; 81: 63-88.
    • (2000) Int J Exp Pathol , vol.81 , pp. 63-88
    • Ferns, G.A.1    Avades, T.Y.2
  • 138
    • 0029098078 scopus 로고
    • The intima. Soil for atherosclerosis and restenosis
    • Schwartz SM, deBlois D, O'Brien ER. The intima. Soil for atherosclerosis and restenosis. Circ Res 1995; 77: 445-65.
    • (1995) Circ Res , vol.77 , pp. 445-465
    • Schwartz, S.M.1    deBlois, D.2    O'Brien, E.R.3
  • 139
    • 0028947782 scopus 로고
    • Serial intravascular ultrasound studies fail to show evidence of chronic Palmaz-Schatz stent recoil
    • Painter JA, Mintz GS, Wong SC, et al. Serial intravascular ultrasound studies fail to show evidence of chronic Palmaz-Schatz stent recoil. Am J Cardiol 1995; 75: 398-400.
    • (1995) Am J Cardiol , vol.75 , pp. 398-400
    • Painter, J.A.1    Mintz, G.S.2    Wong, S.C.3
  • 140
    • 0030895089 scopus 로고    scopus 로고
    • Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia. A serial intravascular ultrasound study
    • Kornowski R, Mintz GS, Kent KM, et al. Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia. A serial intravascular ultrasound study. Circulation 1997; 95: 1366-9.
    • (1997) Circulation , vol.95 , pp. 1366-1369
    • Kornowski, R.1    Mintz, G.S.2    Kent, K.M.3
  • 141
    • 0029585327 scopus 로고
    • Interrelation between atherosclerosis and restenosis
    • Kranzhofer R, Libby P. Interrelation between atherosclerosis and restenosis. Z Kardiol 1995; 84 (Suppl 4): 125-8.
    • (1995) Z Kardiol , vol.84 , Issue.SUPPL. 4 , pp. 125-128
    • Kranzhofer, R.1    Libby, P.2
  • 143
    • 0031593126 scopus 로고    scopus 로고
    • The pathogenesis of atherosclerosis
    • Schachter M. The pathogenesis of atherosclerosis. Int J Cardiol 1997; 62 (Suppl 2): S3-S7.
    • (1997) Int J Cardiol , vol.62 , Issue.SUPPL. 2
    • Schachter, M.1
  • 144
    • 0037112738 scopus 로고    scopus 로고
    • Smooth-muscle progenitor cells of bone marrow origin contribute to the development of neointimal thickenings in rat aortic allografts and injured rat carotid arteries
    • Religa P, Bojakowski K, Maksymowicz M, et al. Smooth-muscle progenitor cells of bone marrow origin contribute to the development of neointimal thickenings in rat aortic allografts and injured rat carotid arteries. Transplantation 2002; 74: 1310-5.
    • (2002) Transplantation , vol.74 , pp. 1310-1315
    • Religa, P.1    Bojakowski, K.2    Maksymowicz, M.3
  • 145
    • 0038433336 scopus 로고    scopus 로고
    • Migration of adventitial myofibroblasts following vascular balloon injury: Insights from in vivo gene transfer to rat carotid arteries
    • Siow RC, Mallawaarachchi CM, Weissberg PL. Migration of adventitial myofibroblasts following vascular balloon injury: insights from in vivo gene transfer to rat carotid arteries. Cardiovasc Res 2003; 59: 212-21.
    • (2003) Cardiovasc Res , vol.59 , pp. 212-221
    • Siow, R.C.1    Mallawaarachchi, C.M.2    Weissberg, P.L.3
  • 146
    • 34347375949 scopus 로고    scopus 로고
    • The role of vascular stem cells in atherogenesis and post-angioplasty restenosis
    • Qian H, Yang Y, Li J, Huang J, Dou K, Yang G. The role of vascular stem cells in atherogenesis and post-angioplasty restenosis. Ageing Res Rev 2007; 6: 109-27.
    • (2007) Ageing Res Rev , vol.6 , pp. 109-127
    • Qian, H.1    Yang, Y.2    Li, J.3    Huang, J.4    Dou, K.5    Yang, G.6
  • 147
    • 0037173080 scopus 로고    scopus 로고
    • Statin therapy accelerates reendothelialization: A novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells
    • Walter DH, Rittig K, Bahlmann FH, et al. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 2002; 105: 3017-24.
    • (2002) Circulation , vol.105 , pp. 3017-3024
    • Walter, D.H.1    Rittig, K.2    Bahlmann, F.H.3
  • 148
    • 0346157997 scopus 로고    scopus 로고
    • Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury
    • Iwakura A, Luedemann C, Shastry S, et al. Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury. Circulation 2003; 108: 3115-21.
    • (2003) Circulation , vol.108 , pp. 3115-3121
    • Iwakura, A.1    Luedemann, C.2    Shastry, S.3
  • 149
    • 0020502095 scopus 로고
    • Mechanisms of stenosis after arterial injury
    • Clowes AW, Reidy MA, Clowes MM. Mechanisms of stenosis after arterial injury. Lab Invest 1983; 49: 208-15.
    • (1983) Lab Invest , vol.49 , pp. 208-215
    • Clowes, A.W.1    Reidy, M.A.2    Clowes, M.M.3
  • 150
    • 68349086694 scopus 로고    scopus 로고
    • Glycaemic control and restenosis after percutaneous coronary interventions in patients with diabetes mellitus: A report from the Insulin Diabetes Angioplasty study
    • Hage C, Norhammar A, Grip L, et al. Glycaemic control and restenosis after percutaneous coronary interventions in patients with diabetes mellitus: a report from the Insulin Diabetes Angioplasty study. Diab Vasc Dis Res 2009; 6: 71-9.
    • (2009) Diab Vasc Dis Res , vol.6 , pp. 71-79
    • Hage, C.1    Norhammar, A.2    Grip, L.3
  • 151
    • 33846783062 scopus 로고    scopus 로고
    • Preprocedure hyperglycemia is more strongly associated with restenosis in diabetic patients after percutaneous coronary intervention than is hemoglobin A1C
    • Lindsay J, Sharma AK, Canos D, et al. Preprocedure hyperglycemia is more strongly associated with restenosis in diabetic patients after percutaneous coronary intervention than is hemoglobin A1C. Cardiovasc Revasc Med 2007; 8: 15-20.
    • (2007) Cardiovasc Revasc Med , vol.8 , pp. 15-20
    • Lindsay, J.1    Sharma, A.K.2    Canos, D.3
  • 152
    • 39749195580 scopus 로고    scopus 로고
    • An increase in HbA1c after percutaneous coronary intervention raises the risk for restenosis in patients without type 2 diabetes mellitus
    • Diedrichs H, Pfister R, Hagemeister J, et al. An increase in HbA1c after percutaneous coronary intervention raises the risk for restenosis in patients without type 2 diabetes mellitus. Diabet Med 2008; 25: 228-31.
    • (2008) Diabet Med , vol.25 , pp. 228-231
    • Diedrichs, H.1    Pfister, R.2    Hagemeister, J.3
  • 153
    • 46249085232 scopus 로고    scopus 로고
    • Association between Creactive protein and angiographic restenosis after bare metal stents: An updated and comprehensive meta-analysis of 2747 patients
    • Ferrante G, Niccoli G, Biasucci LM, et al. Association between Creactive protein and angiographic restenosis after bare metal stents: an updated and comprehensive meta-analysis of 2747 patients. Cardiovasc Revasc Med 2008; 9: 156-65.
    • (2008) Cardiovasc Revasc Med , vol.9 , pp. 156-165
    • Ferrante, G.1    Niccoli, G.2    Biasucci, L.M.3
  • 154
    • 0026532669 scopus 로고
    • In vivo proliferation of rat vascular smooth muscle in relation to diabetes mellitus insulin-like growth factor I and insulin
    • Bornfeldt KE, Arnqvist HJ, Capron L. In vivo proliferation of rat vascular smooth muscle in relation to diabetes mellitus insulin-like growth factor I and insulin. Diabetologia 1992; 35: 104-8.
    • (1992) Diabetologia , vol.35 , pp. 104-108
    • Bornfeldt, K.E.1    Arnqvist, H.J.2    Capron, L.3
  • 155
    • 0035912899 scopus 로고    scopus 로고
    • Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats
    • Indolfi C, Torella D, Cavuto L, et al. Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats. Circulation 2001; 103: 2980-6.
    • (2001) Circulation , vol.103 , pp. 2980-2986
    • Indolfi, C.1    Torella, D.2    Cavuto, L.3
  • 156
    • 0033398589 scopus 로고    scopus 로고
    • Balloon catheter vascular injury of the alloxan-induced diabetic rabbit: The role of insulin-like growth factor-1
    • Schiller NK, McNamara DB. Balloon catheter vascular injury of the alloxan-induced diabetic rabbit: the role of insulin-like growth factor-1. Mol Cell Biochem 1999; 202: 159-67.
    • (1999) Mol Cell Biochem , vol.202 , pp. 159-167
    • Schiller, N.K.1    McNamara, D.B.2
  • 158
    • 0035859799 scopus 로고    scopus 로고
    • Neointimal hyperplasia after arterial injury is increased in a rat model of non-insulin-dependent diabetes mellitus
    • Park SH, Marso SP, Zhou Z, Foroudi F, Topol EJ, Lincoff AM. Neointimal hyperplasia after arterial injury is increased in a rat model of non-insulin-dependent diabetes mellitus. Circulation 2001; 104: 815-9.
    • (2001) Circulation , vol.104 , pp. 815-819
    • Park, S.H.1    Marso, S.P.2    Zhou, Z.3    Foroudi, F.4    Topol, E.J.5    Lincoff, A.M.6
  • 159
    • 0027959886 scopus 로고
    • Increased SMC proliferation after endothelial injury in hyperinsulinemic obese Zucker rats
    • Ridray S, Heudes D, Michel O, Penicaud L, Ktorza A. Increased SMC proliferation after endothelial injury in hyperinsulinemic obese Zucker rats. Am J Physiol 1994; 267: H1976-H1983.
    • (1994) Am J Physiol , vol.267
    • Ridray, S.1    Heudes, D.2    Michel, O.3    Penicaud, L.4    Ktorza, A.5
  • 160
    • 0034042021 scopus 로고    scopus 로고
    • Increased hyaluronan and hyaluronidase production and hyaluronan degradation in injured aorta of insulin-resistant rats
    • Chajara A, Raoudi M, Delpech B, Leroy M, Basuyau JP, Levesque H. Increased hyaluronan and hyaluronidase production and hyaluronan degradation in injured aorta of insulin-resistant rats. Arterioscler Thromb Vasc Biol 2000; 20: 1480-7.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1480-1487
    • Chajara, A.1    Raoudi, M.2    Delpech, B.3    Leroy, M.4    Basuyau, J.P.5    Levesque, H.6
  • 161
    • 0034063211 scopus 로고    scopus 로고
    • Increased atherogenesis in Otsuka Long-Evans Tokushima fatty rats before the onset of diabetes mellitus: Association with overexpression of PDGF betareceptors in aortic smooth muscle cells
    • Tamura K, Kanzaki T, Tashiro J, et al. Increased atherogenesis in Otsuka Long-Evans Tokushima fatty rats before the onset of diabetes mellitus: association with overexpression of PDGF betareceptors in aortic smooth muscle cells. Atherosclerosis 2000; 149: 351-8.
    • (2000) Atherosclerosis , vol.149 , pp. 351-358
    • Tamura, K.1    Kanzaki, T.2    Tashiro, J.3
  • 162
    • 26244463378 scopus 로고    scopus 로고
    • Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals
    • Jonas M, Edelman ER, Groothuis A, Baker AB, Seifert P, Rogers C. Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals. Circ Res 2005; 97: 725-33.
    • (2005) Circ Res , vol.97 , pp. 725-733
    • Jonas, M.1    Edelman, E.R.2    Groothuis, A.3    Baker, A.B.4    Seifert, P.5    Rogers, C.6
  • 163
    • 0022445661 scopus 로고
    • Growth-promoting effects of diabetes and insulin on arteries. An in vivo study of rat aorta
    • Capron L, Jarnet J, Kazandjian S, Housset E. Growth-promoting effects of diabetes and insulin on arteries. An in vivo study of rat aorta. Diabetes 1986; 35: 973-8.
    • (1986) Diabetes , vol.35 , pp. 973-978
    • Capron, L.1    Jarnet, J.2    Kazandjian, S.3    Housset, E.4
  • 164
    • 0026716321 scopus 로고
    • In vivo effect of insulin on the acute proliferative response of the rat aorta to injury
    • Ridray S, Ktorza A, Picon L, Capron L. In vivo effect of insulin on the acute proliferative response of the rat aorta to injury. Arterioscler Thromb 1992; 12: 633-8.
    • (1992) Arterioscler Thromb , vol.12 , pp. 633-638
    • Ridray, S.1    Ktorza, A.2    Picon, L.3    Capron, L.4
  • 165
    • 0037662849 scopus 로고    scopus 로고
    • Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury
    • Kubota T, Kubota N, Moroi M, et al. Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury. Circulation 2003; 107: 3073-80.
    • (2003) Circulation , vol.107 , pp. 3073-3080
    • Kubota, T.1    Kubota, N.2    Moroi, M.3
  • 166
    • 27344455048 scopus 로고    scopus 로고
    • Anti-atherogenic effect of insulin in vivo
    • Kim T, Chan KK, Dhaliwall JK, et al. Anti-atherogenic effect of insulin in vivo. J Vasc Res 2005; 42: 455-62.
    • (2005) J Vasc Res , vol.42 , pp. 455-462
    • Kim, T.1    Chan, K.K.2    Dhaliwall, J.K.3
  • 167
    • 67650290816 scopus 로고    scopus 로고
    • Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury
    • Breen DM, Chan KK, Dhaliwall JK, et al. Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury. Arterioscler Thromb Vasc Biol 2009; 29: 1060-6.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1060-1066
    • Breen, D.M.1    Chan, K.K.2    Dhaliwall, J.K.3
  • 168
    • 0033743379 scopus 로고    scopus 로고
    • In vivo transfer of human hepatocyte growth factor gene accelerates reendothelialization and inhibits neointimal formation after balloon injury in rat model
    • Hayashi K, Nakamura S, Morishita R, et al. In vivo transfer of human hepatocyte growth factor gene accelerates reendothelialization and inhibits neointimal formation after balloon injury in rat model. Gene Ther 2000; 7: 1664-71.
    • (2000) Gene Ther , vol.7 , pp. 1664-1671
    • Hayashi, K.1    Nakamura, S.2    Morishita, R.3
  • 169
    • 79955598754 scopus 로고    scopus 로고
    • In vivo effect of insulin to decrease matrix metalloproteinase (MMP)-2 activity
    • Dhaliwall JK, Chan KK, Al Koudsi N, et al. In vivo effect of insulin to decrease matrix metalloproteinase (MMP)-2 activity. Diabetes (Suppl 1) 2005; 54: A189.
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 1
    • Dhaliwall, J.K.1    Chan, K.K.2    Al Koudsi, N.3
  • 170
    • 33645466068 scopus 로고    scopus 로고
    • Insulin stimulates arterial neointima formation in normal rats after balloon injury
    • Foster E, Zhang S, Kahn AM. Insulin stimulates arterial neointima formation in normal rats after balloon injury. Diabetes Obes Metab 2006; 8: 348-51.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 348-351
    • Foster, E.1    Zhang, S.2    Kahn, A.M.3
  • 171
    • 0042090554 scopus 로고    scopus 로고
    • Intimal hyperplasia following carotid endarterectomy in an insulin-resistant rat model
    • Brown AT, Smith TP, Cruz CP, et al. Intimal hyperplasia following carotid endarterectomy in an insulin-resistant rat model. Metabolism 2003; 52: 834-9.
    • (2003) Metabolism , vol.52 , pp. 834-839
    • Brown, A.T.1    Smith, T.P.2    Cruz, C.P.3
  • 172
    • 0028598170 scopus 로고
    • Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat
    • Lee MK, Miles PD, Khoursheed M, Gao KM, Moossa AR, Olefsky JM. Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes 1994; 43: 1435-9.
    • (1994) Diabetes , vol.43 , pp. 1435-1439
    • Lee, M.K.1    Miles, P.D.2    Khoursheed, M.3    Gao, K.M.4    Moossa, A.R.5    Olefsky, J.M.6
  • 174
    • 76049103621 scopus 로고    scopus 로고
    • Insulin Inhibits and Oral Sucrose Increases Neointimal Growth after Arterial Injury in Rats
    • Breen DM, Dhaliwall JK, Chan KK, et al. Insulin Inhibits and Oral Sucrose Increases Neointimal Growth after Arterial Injury in Rats. J Vasc Res 2010; 47: 412-22.
    • (2010) J Vasc Res , vol.47 , pp. 412-422
    • Breen, D.M.1    Dhaliwall, J.K.2    Chan, K.K.3
  • 175
    • 58149520029 scopus 로고    scopus 로고
    • Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling, and amplifies neointima formation in the balloon-injured rat artery
    • Pu Q, Chang Y, Zhang C, Cai Y, Hassid A. Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling, and amplifies neointima formation in the balloon-injured rat artery. Am J Physiol Heart Circ Physiol 2009; 296: H132-H139.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Pu, Q.1    Chang, Y.2    Zhang, C.3    Cai, Y.4    Hassid, A.5
  • 176
    • 16844370268 scopus 로고    scopus 로고
    • Regulation of insulin signalling by hyperinsulinaemia: Role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
    • Ueno M, Carvalheira JB, Tambascia RC, et al. Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 2005; 48: 506-18.
    • (2005) Diabetologia , vol.48 , pp. 506-518
    • Ueno, M.1    Carvalheira, J.B.2    Tambascia, R.C.3
  • 177
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle
    • Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle. J Clin Invest 2000; 105: 311-20.
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3
  • 178
    • 0032719024 scopus 로고    scopus 로고
    • Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
    • Jiang ZY, Lin YW, Clemont A, et al. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest 1999; 104: 447-57.
    • (1999) J Clin Invest , vol.104 , pp. 447-457
    • Jiang, Z.Y.1    Lin, Y.W.2    Clemont, A.3
  • 179
    • 77958510970 scopus 로고    scopus 로고
    • Postprocedure administration of insulin in canine autologous vein grafting: A potential strategy to attenuate intimal hyperplasia
    • Zhou N, Yu QJ, Si R, et al. Postprocedure administration of insulin in canine autologous vein grafting: a potential strategy to attenuate intimal hyperplasia. J Cardiovasc Pharmacol 2010; 56: 402-12.
    • (2010) J Cardiovasc Pharmacol , vol.56 , pp. 402-412
    • Zhou, N.1    Yu, Q.J.2    Si, R.3
  • 180
    • 63849242880 scopus 로고    scopus 로고
    • Insulin glargine reduces carotid intimal hyperplasia after balloon catheter injury in Zucker fatty rats possibly by reduction in oxidative stress
    • Murthy SN, Sukhanov S, McGee J, et al. Insulin glargine reduces carotid intimal hyperplasia after balloon catheter injury in Zucker fatty rats possibly by reduction in oxidative stress. Mol Cell Biochem 2009; 330: 1-8.
    • (2009) Mol Cell Biochem , vol.330 , pp. 1-8
    • Murthy, S.N.1    Sukhanov, S.2    McGee, J.3
  • 181
    • 0025437434 scopus 로고
    • Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation
    • Cercek B, Fishbein MC, Forrester JS, Helfant RH, Fagin JA. Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation. Circ Res 1990; 66: 1755-60.
    • (1990) Circ Res , vol.66 , pp. 1755-1760
    • Cercek, B.1    Fishbein, M.C.2    Forrester, J.S.3    Helfant, R.H.4    Fagin, J.A.5
  • 182
    • 0028885821 scopus 로고
    • Stabile D-peptide analog of insulin-like growth factor-1 inhibits smooth muscle cell proliferation after carotid ballooning injury in the rat
    • Hayry P, Myllarniemi M, Aavik E, et al. Stabile D-peptide analog of insulin-like growth factor-1 inhibits smooth muscle cell proliferation after carotid ballooning injury in the rat. FASEB J 1995; 9: 1336-44.
    • (1995) FASEB J , vol.9 , pp. 1336-1344
    • Hayry, P.1    Myllarniemi, M.2    Aavik, E.3
  • 183
    • 8444219631 scopus 로고    scopus 로고
    • Dominant negative insulin-like growth factor-1 receptor inhibits neointimal formation through suppression of vascular smooth muscle cell migration and proliferation, and induction of apoptosis
    • Lim HJ, Park HY, Ko YG, et al. Dominant negative insulin-like growth factor-1 receptor inhibits neointimal formation through suppression of vascular smooth muscle cell migration and proliferation, and induction of apoptosis. Biochem Biophys Res Commun 2004; 325: 1106-14.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 1106-1114
    • Lim, H.J.1    Park, H.Y.2    Ko, Y.G.3
  • 184
    • 0036818716 scopus 로고    scopus 로고
    • Arterial injury in mice with severe insulin-like growth factor-1 (IGF-1) deficiency
    • Li H, Dimayuga P, Yamashita M, et al. Arterial injury in mice with severe insulin-like growth factor-1 (IGF-1) deficiency. J Cardiovasc Pharmacol Ther 2002; 7: 227-33.
    • (2002) J Cardiovasc Pharmacol Ther , vol.7 , pp. 227-233
    • Li, H.1    Dimayuga, P.2    Yamashita, M.3
  • 185
    • 0034922869 scopus 로고    scopus 로고
    • Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury
    • Zhu B, Zhao G, Witte DP, Hui DY, Fagin JA. Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury. Endocrinology 2001; 142: 3598-606.
    • (2001) Endocrinology , vol.142 , pp. 3598-3606
    • Zhu, B.1    Zhao, G.2    Witte, D.P.3    Hui, D.Y.4    Fagin, J.A.5
  • 186
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS) Group
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352: 854-65.
    • (1998) Lancet , vol.352 , pp. 854-865
  • 187
    • 48349116165 scopus 로고    scopus 로고
    • Metformin: Effects on micro and macrovascular complications in type 2 diabetes
    • Bailey CJ. Metformin: effects on micro and macrovascular complications in type 2 diabetes. Cardiovasc Drugs Ther 2008; 22: 215-24.
    • (2008) Cardiovasc Drugs Ther , vol.22 , pp. 215-224
    • Bailey, C.J.1
  • 188
    • 0842306338 scopus 로고    scopus 로고
    • Effect of metformin treatment on multiple cardiovascular disease risk factors in patients with type 2 diabetes mellitus
    • Abbasi F, Chu JW, McLaughlin T, Lamendola C, Leary ET, Reaven GM. Effect of metformin treatment on multiple cardiovascular disease risk factors in patients with type 2 diabetes mellitus. Metabolism 2004; 53: 159-64.
    • (2004) Metabolism , vol.53 , pp. 159-164
    • Abbasi, F.1    Chu, J.W.2    McLaughlin, T.3    Lamendola, C.4    Leary, E.T.5    Reaven, G.M.6
  • 189
    • 0029778182 scopus 로고    scopus 로고
    • Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients
    • Marfella R, Acampora R, Verrazzo G, et al. Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients. Diabetes Care 1996; 19: 934-9.
    • (1996) Diabetes Care , vol.19 , pp. 934-939
    • Marfella, R.1    Acampora, R.2    Verrazzo, G.3
  • 190
    • 0033958239 scopus 로고    scopus 로고
    • Metformin improves vascular function in insulin-resistant rats
    • Katakam PV, Ujhelyi MR, Hoenig M, Miller AW. Metformin improves vascular function in insulin-resistant rats. Hypertension 2000; 35: 108-12.
    • (2000) Hypertension , vol.35 , pp. 108-112
    • Katakam, P.V.1    Ujhelyi, M.R.2    Hoenig, M.3    Miller, A.W.4
  • 191
    • 33644747421 scopus 로고    scopus 로고
    • Activation of the AMPactivated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
    • Davis BJ, Xie Z, Viollet B, Zou MH. Activation of the AMPactivated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes 2006; 55: 496-505.
    • (2006) Diabetes , vol.55 , pp. 496-505
    • Davis, B.J.1    Xie, Z.2    Viollet, B.3    Zou, M.H.4
  • 192
    • 2342446628 scopus 로고    scopus 로고
    • Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes
    • Matsumoto K, Sera Y, Abe Y, Tominaga T, Yeki Y, Miyake S. Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes. Diabetes Res Clin Pract 2004; 64: 225-8.
    • (2004) Diabetes Res Clin Pract , vol.64 , pp. 225-228
    • Matsumoto, K.1    Sera, Y.2    Abe, Y.3    Tominaga, T.4    Yeki, Y.5    Miyake, S.6
  • 193
    • 46749120271 scopus 로고    scopus 로고
    • Metformin, arterial function, intima-media thickness and nitroxidation in metabolic syndrome: The mefisto study
    • Meaney E, Vela A, Samaniego V, et al. Metformin, arterial function, intima-media thickness and nitroxidation in metabolic syndrome: the mefisto study. Clin Exp Pharmacol Physiol 2008; 35: 895-903.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 895-903
    • Meaney, E.1    Vela, A.2    Samaniego, V.3
  • 194
    • 2542425599 scopus 로고    scopus 로고
    • Relation of metformin treatment to clinical events in diabetic patients undergoing percutaneous intervention
    • Kao J, Tobis J, McClelland RL, et al. Relation of metformin treatment to clinical events in diabetic patients undergoing percutaneous intervention. Am J Cardiol 2004; 93: 1347-50.
    • (2004) Am J Cardiol , vol.93 , pp. 1347-1350
    • Kao, J.1    Tobis, J.2    McClelland, R.L.3
  • 195
    • 35448967441 scopus 로고    scopus 로고
    • Angiographic and clinical outcomes of rosiglitazone in patients with type 2 diabetes mellitus after percutaneous coronary interventions: A single center experience
    • Fang CC, Ng Jao YT, Yi C, Yu CL, Chen CL, Wang SP. Angiographic and clinical outcomes of rosiglitazone in patients with type 2 diabetes mellitus after percutaneous coronary interventions: a single center experience. Angiology 2007; 58: 523-34.
    • (2007) Angiology , vol.58 , pp. 523-534
    • Fang, C.C.1    Ng Jao, Y.T.2    Yi, C.3    Yu, C.L.4    Chen, C.L.5    Wang, S.P.6
  • 196
    • 0018739904 scopus 로고
    • Comparative effects of metformin and phenformin on the progression and regression of cholesterol induced athreosclerosis in rabbits
    • Marquie G. Comparative effects of metformin and phenformin on the progression and regression of cholesterol induced athreosclerosis in rabbits. Paroi Arterielle 1979; 5: 209-18.
    • (1979) Paroi Arterielle , vol.5 , pp. 209-218
    • Marquie, G.1
  • 197
    • 0017858366 scopus 로고
    • Effect of metformin on lipid metabolism in the rabbit aortic wall
    • Marquie G. Effect of metformin on lipid metabolism in the rabbit aortic wall. Atherosclerosis 1978; 30: 165-75.
    • (1978) Atherosclerosis , vol.30 , pp. 165-175
    • Marquie, G.1
  • 198
    • 0020639876 scopus 로고
    • Metformin action on lipid metabolism in lesions of experimental aortic atherosclerosis of rabbits
    • Marquie G. Metformin action on lipid metabolism in lesions of experimental aortic atherosclerosis of rabbits. Atherosclerosis 1983; 47: 7-17.
    • (1983) Atherosclerosis , vol.47 , pp. 7-17
    • Marquie, G.1
  • 199
    • 78751615823 scopus 로고    scopus 로고
    • Pioglitazone modulates the balance of effector and regulatory T cells in apolipoprotein E deficient mice
    • Tian Y, Yuan Z, Liu Y, et al. Pioglitazone modulates the balance of effector and regulatory T cells in apolipoprotein E deficient mice. Nutr Metab Cardiovasc Dis 2011; 21: 25-32.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , pp. 25-32
    • Tian, Y.1    Yuan, Z.2    Liu, Y.3
  • 200
    • 48049096575 scopus 로고    scopus 로고
    • Rosiglitazone promotes atherosclerotic plaque stability in fat-fed ApoE-knockout mice
    • Zhou M, Xu H, Pan L, Wen J, Liao W, Chen K. Rosiglitazone promotes atherosclerotic plaque stability in fat-fed ApoE-knockout mice. Eur J Pharmacol 2008; 590: 297-302.
    • (2008) Eur J Pharmacol , vol.590 , pp. 297-302
    • Zhou, M.1    Xu, H.2    Pan, L.3    Wen, J.4    Liao, W.5    Chen, K.6
  • 201
    • 0035093258 scopus 로고    scopus 로고
    • Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
    • Collins AR, Meehan WP, Kintscher U, et al. Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol 2001; 21: 365-71.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 365-371
    • Collins, A.R.1    Meehan, W.P.2    Kintscher, U.3
  • 202
    • 0035943010 scopus 로고    scopus 로고
    • Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia
    • Aizawa Y, Kawabe J, Hasebe N, Takehara N, Kikuchi K. Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia. Circulation 2001; 104: 455-60.
    • (2001) Circulation , vol.104 , pp. 455-460
    • Aizawa, Y.1    Kawabe, J.2    Hasebe, N.3    Takehara, N.4    Kikuchi, K.5
  • 203
    • 63449092586 scopus 로고    scopus 로고
    • New mechanism of rosiglitazone to reduce neointimal hyperplasia: Activation of glycogen synthase kinase-3beta followed by inhibition of MMP-9
    • Lee CS, Kwon YW, Yang HM, et al. New mechanism of rosiglitazone to reduce neointimal hyperplasia: activation of glycogen synthase kinase-3beta followed by inhibition of MMP-9. Arterioscler Thromb Vasc Biol 2009; 29: 472-9.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 472-479
    • Lee, C.S.1    Kwon, Y.W.2    Yang, H.M.3
  • 204
    • 0029861097 scopus 로고    scopus 로고
    • Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
    • Law RE, Meehan WP, Xi XP, et al. Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia. J Clin Invest 1996; 98: 1897-905.
    • (1996) J Clin Invest , vol.98 , pp. 1897-1905
    • Law, R.E.1    Meehan, W.P.2    Xi, X.P.3
  • 205
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
    • Dormandy JA, Charbonnel B, Eckland DJ, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 2005; 366: 1279-89.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3
  • 206
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356: 2457-71.
    • (2007) N Engl J Med , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 207
    • 77953638099 scopus 로고    scopus 로고
    • Critics press FDA to act on evidence of rosiglitazone's cardiac safety issues
    • Mitka M. Critics press FDA to act on evidence of rosiglitazone's cardiac safety issues. JAMA 2010; 303: 2341-2.
    • (2010) JAMA , vol.303 , pp. 2341-2342
    • Mitka, M.1
  • 208
    • 58549087924 scopus 로고    scopus 로고
    • Effect of thiazolidinediones on in-stent restenosis in patients after coronary stenting: A meta-analysis of randomized controlled trials
    • Geng DF, Jin DM, Wu W, Wang Z, Wang JF. Effect of thiazolidinediones on in-stent restenosis in patients after coronary stenting: a meta-analysis of randomized controlled trials. Atherosclerosis 2009; 202: 521-8.
    • (2009) Atherosclerosis , vol.202 , pp. 521-528
    • Geng, D.F.1    Jin, D.M.2    Wu, W.3    Wang, Z.4    Wang, J.F.5
  • 209
    • 0036467866 scopus 로고    scopus 로고
    • Impact of troglitazone on coronary stent implantation using small stents in patients with type 2 diabetes mellitus
    • Takagi T, Yamamuro A, Tamita K, et al. Impact of troglitazone on coronary stent implantation using small stents in patients with type 2 diabetes mellitus. Am J Cardiol 2002; 89: 318-22.
    • (2002) Am J Cardiol , vol.89 , pp. 318-322
    • Takagi, T.1    Yamamuro, A.2    Tamita, K.3
  • 210
    • 7444231513 scopus 로고    scopus 로고
    • Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes
    • Choi D, Kim SK, Choi SH, et al. Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes. Diabetes Care 2004; 27: 2654-60.
    • (2004) Diabetes Care , vol.27 , pp. 2654-2660
    • Choi, D.1    Kim, S.K.2    Choi, S.H.3
  • 211
    • 33644875072 scopus 로고    scopus 로고
    • A randomized comparison of pioglitazone to inhibit restenosis after coronary stenting in patients with type 2 diabetes
    • Nishio K, Sakurai M, Kusuyama T, et al. A randomized comparison of pioglitazone to inhibit restenosis after coronary stenting in patients with type 2 diabetes. Diabetes Care 2006; 29: 101-6.
    • (2006) Diabetes Care , vol.29 , pp. 101-106
    • Nishio, K.1    Sakurai, M.2    Kusuyama, T.3
  • 212
    • 58649091997 scopus 로고    scopus 로고
    • Predictive factors for in-stent late loss and coronary lesion progression in patients with type 2 diabetes mellitus randomized to rosiglitazone or placebo
    • Finn AV, Oh JS, Hendricks M, et al. Predictive factors for in-stent late loss and coronary lesion progression in patients with type 2 diabetes mellitus randomized to rosiglitazone or placebo. Am Heart J 2009; 157: 383-8.
    • (2009) Am Heart J , vol.157 , pp. 383-388
    • Finn, A.V.1    Oh, J.S.2    Hendricks, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.