Intimal hyperplasia following carotid endarterectomy in an insulin-resistant rat model

Metabolism: Clinical and Experimental

Volumn 52, Issue 7, 2003, Pages 834-839

  Brown, Aliza T ^a,b   Smith, Todd P ^a,b   Cruz, Carlos P ^a,b   Poirier, Lionel A ^a,b   Simmons, Debra ^a,b   Williams, D Keith ^a,b   Wang, Yunfang ^a,b   Eidt, John F ^a,b   Moursi, Mohammed M ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CARBOHYDRATE; CYSTATHIONINE BETA SYNTHASE; FOLIC ACID; HOMOCYSTEINE; INSULIN; LIPID; SUCROSE;

AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD; BODY WEIGHT; CARDIOVASCULAR DISEASE; CAROTID ARTERY; CAROTID ENDARTERECTOMY; COMPUTER ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; COST EFFECTIVENESS ANALYSIS; DIET SUPPLEMENTATION; DIET THERAPY; ENZYME ACTIVITY; FEEDING; FOLIC ACID BLOOD LEVEL; HYPERHOMOCYSTEINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; LIVER; LOW FAT DIET; MALE; METABOLIC PARAMETERS; MORPHOMETRICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; RISK FACTOR; STENOSIS; SURGICAL TECHNIQUE; VASCULAR DISEASE;

EID: 0042090554     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(03)00097-0     Document Type: Article

References (25)

1. Reaven GM: The role of insulin resistance and hyperinsulinemia in coronary heart disease. Metabolism 41:16-19, 1992
2. DeFronzo RA: Insulin resistance, hyperinsulinemia, and coronary artery disease: A complex metabolic web. Coron Artery Dis 3:11-25, 1992
3. Aronson D, Bloomgarden Z, Rayfield EJ: Potential mechanisms promoting restenosis in diabetic patients. J Am Coll Cardiol 27:528-535, 1996
4. Ross R: Atherosclerosis - An inflammatory disease. N Engl J Med 340:115-126, 1999
5. Stephen D, San H, Yang ZY, et al: Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon. Mol Med 3:593-599, 1997
6. Fonseca V, Dicker-Brown AT, Ranganathan S, et al: Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat. Metabolism 49:736-741, 2000
7. Barnard RJ, Faria DJ, Menges JE, et al: Effects of a high-fat, sucrose diet on serum insulin and related atherosclerotic risk factors in rats. Atherosclerosis 100:229-236, 1993
8. Barnard RJ, Youngren JF, Martin DA: Diet, not aging, causes skeletal muscle insulin resistance. Gerontology 41:205-211, 1995
9. North American Symptomatic Carotid Endarterectomy Trial Collaborators (NASCET): Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325:445-453, 1991
10. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study (ACAS): Endarterectomy for asymptomatic carotid artery stenosis. JAMA 273:1421-1428, 1995
11. Healy DA, Zeirler RE, Nicholls SC, et al: Long-term follow-up and clinical outcome of carotid restenosis. J Vasc Surg 10:662-669, 1989
12. Southern FN, Cruz N, Fink LM, et al: Hyperhomocysteinemia increases intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg 28:909-918, 1998
13. Southern FN, Eidt J, Drouilhet J, et al: Increasing levels of dietary homocysteine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia. Atherosclerosis 158:129-138, 2001
14. Smith TP, Cruz CP, Brown AT, et al: Folate supplementation inhibits intimal hyperplasia induced by a high-homocysteine diet in a rat carotid endarterectomy model. J Vasc Surg 34:474-481, 2001
15. Cruz CP, Eidt JF, Drouilhet J, et al: Saratin, an inhibitor of von Willebrand factor-dependent platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg 34:724-729, 2001
16. Ubbink J, Hayward VW, Bissport S: Rapid high performance liquid chromatographic assay for total homocysteine levels in human serum. J Chromatogr 565:441-446, 1991
17. Law MM, Gelabert HA, Moore WS, et al: Cigarette smoking increases the development of intimal hyperplasia after vascular injury. J Vasc Surg 23:401-409, 1996
18. Sanchez-Margalet V, Valle M, Ruz FJ, et al: Elevated plasma total homocysteine levels in hyperinsulinemic obese subjects. J Nutr Biochem 13:75-79, 2002
19. Meigs JB, Jacques PF, Selhub J, et al: Framingham Offspring Study. Fasting plasma homocysteine levels in the insulin resistance syndrome. Diabetes Care 24:1403-1410, 2001
20. Kang SS, Wong PW, Malinow MR: Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Ann Rev Nutr 12:279-298, 1992
21. Ueland PM, Refsum H, Stabler SP, et al: Total homocysteine in plasma or serum: Methods and clinical applications. Clin Chem 39: 1764-1779, 1993
22. Roberts CK, Barnard RJ, Liang KH, et al: Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: Implications for obesity and hyperlipidemia. Atherosclerosis 161:133-141, 2002
23. Youngren JF, Paik J, Barnard RJ: Impaired insulin-receptor autophosphorylation is an early defect in fat-fed, insulin resistant rats. J Appl Physiol 91:2240-2247, 2001
24. Poirier LA, Wise CK, Delongchamp RR, et al: Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: Correlations with diet. Cancer Epidemiol Biomarkers Prev 10:649-655, 2001
25. Rogers AE, Newberne PM: Dietary effects on chemical carcinogenesis in animal models for colon and liver tumors. Cancer Res 35:3427-3471, 1975