Insulin inhibits migration of vascular smooth muscle cells with inducible nitric oxide synthase

Hypertension

Volumn 35, Issue 1 II, 2000, Pages 303-306

  Kahn, Andrew M ^a,c   Allen, Julius C ^b   Seidel, Charles L ^b   Zhang, Sui ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Cyclic 3',5'guanosine monophosphate; Insulin; Muscle, smooth, vascular; Nitric oxide

Indexed keywords

CYCLIC GMP; INSULIN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; CELL MIGRATION; CONFERENCE PAPER; CONTROLLED STUDY; DOG; ENZYME INDUCTION; GEL ELECTROPHORESIS; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RESTENOSIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0033977725     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.35.1.303     Document Type: Conference Paper

References (21)

1. Stout RW. Insulin and atheroma: 20-yr perspective. Diabetes Care. 1990; 13:631-654.
2. Asakura Y, Suzuki M, Nonogi H, Haze K, Sato A, Inada H, Okuda Y, Yamashita K, Harano Y. Restenosis after percutaneous transluminal coronary angioplasty in patients with non-insulin-dependent diabetes mellitus (NIDDM). J Cardiovasc Risk. 1998;5:331-334.
3. Osanai H, Kanayama H, Miyazaki Y, Fukishima A, Shinoda M, Ito T. Usefulness of enhanced insulin secretion during an oral glucose tolerance test as a predictor of restenosis after direct percutaneous transluminal coronary angioplasty during acute myocardial infarction in patients without diabetes mellitus. Am J Cardiol. 1998;81:698-701.
4. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (Lond). 1993;362:801-809.
5. Stout RW. Insulin as a mitogenic factor: role in the pathogenesis of cardiovascular disease. Am J Med. 1991;90:2A-625-2A-645.
6. Grotendorst GR, Chang T, Seppa HEJ, Kleinman HK, Martin GR. Platelet-derived growth factor is a chemoattractant for vascular smooth muscle cells. J Cell Physiol. 1982;113:261-266.
7. Nakao J, Ito H, Kanayasu T, Murota S. Stimulatory effect of insulin on aortic smooth muscle cell migration induced by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid and its modulation by elevated extracellular glucose levels. Diabetes. 1985;34:185-191.
8. Gockerman A, Prevette T, Jones JI, Clemmons DR. Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II. Endocrinology. 1995;136:4168-4173.
9. Bornfeldt KE, Raines EW, Nakano T, Graves LM, Krebs EG, Ross R. Insulin-like growth factor-1 and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J Clin Invest. 1994;93:1266-1274.
10. Kahn AM, Husid A, Allen JC, Seidel CL, Song T. Insulin acutely inhibits cultured vascular smooth muscle cell contraction by a nitric oxide synthase-dependent pathway. Hypertension. 1997;30:928-933.
11. 2+ concentration. Am J Physiol. 1998;274:E885-E892.
12. Dubey RK, Jackson EK, Luscher TF. Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell: role of cyclic-nucleotides and angiotensin, receptors. J Clin Invest. 1995;96:141-149.
13. Weisbrodt NW, Pressley TA, Young-Fang L, Zembowicz MJ, Higham SC, Zembowicz A, Lodato RF, Moody FG. Decreased ileal muscle contractility and increased NOS II expression induced by lipopolysaccharide. Am J Physiol. 1996;271:G454-G450.
14. Seidel CL, Helgason T, Allen JC, Wilson C. Migratory abilities of different vascular cells from the tunica media of canine vessels. Am J Physiol. 1997;272:C847-C852.
15. Schini-Kerth VB, Vanhoutte PM. Nitric oxide synthases in vascular cells. Exp Physiol. 1995;80:885-905.
16. Duff GL, Brechin DJH, Findelstein WE. The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit, IV: the effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit. J Exp Med. 1954;100:371-380.
17. Brown C, Pan X, Hassid A. Nitric oxide and C-type atrial natriuretic peptide stimulate primary aortic smooth muscle cell migration via a cGMP-dependent mechanism: relationship to microfilament dissociation and altered cell morphology. Circ Res. 1999;84:655-667.
18. Verbeuren TJ, Bonhomme E, Laubie M, Simonet S. Evidence for induction of nonendothelial NO synthase in aortas of cholesterol-fed rabbits. J Cardiovasc Pharm. 1993;21:841-845.
19. Yan Z, Hansson GK. Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells. Circ Res. 1998;82:21-29.
20. Sowers JR. Insulin and insulin-like growth factor in normal and pathological cardiovascular physiology. Hypertension. 1997;29:691-699.
21. Reaven GM, Chen YDI. Insulin resistance, its consequences, and coronary heart disease: must we choose one culprit? Circulation. 1996;93: 1780-1783.