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Volumn 87, Issue 3, 2002, Pages 1419-1422

Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations

Author keywords

[No Author keywords available]

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; GLUCOSE; INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; POTASSIUM CHLORIDE; THROMBOPLASTIN;

EID: 0036964978     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.87.3.8462     Document Type: Article
Times cited : (239)

References (20)
  • 1
    • 0029996110 scopus 로고    scopus 로고
    • Egr-1-induced endothelial gene expression: A common theme in vascular injury
    • Khachigian LM, Lindner V, Williams AJ, Collins T. Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 1996;271:1427-31.
    • (1996) Science , vol.271 , pp. 1427-1431
    • Khachigian, L.M.1    Lindner, V.2    Williams, A.J.3    Collins, T.4
  • 3
    • 0029864377 scopus 로고    scopus 로고
    • Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: Role for transcription factor EGR1
    • Maltzman JS, Carmen JA, Monroe JG. Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1. J Exp Med 1996;183:1747-59.
    • (1996) J Exp Med , vol.183 , pp. 1747-1759
    • Maltzman, J.S.1    Carmen, J.A.2    Monroe, J.G.3
  • 4
    • 0029100932 scopus 로고
    • Regulation of the tissue factor gene
    • Mackman N. Regulation of the tissue factor gene. Faseb J 1995;9:883-9.
    • (1995) Faseb J , vol.9 , pp. 883-889
    • Mackman, N.1
  • 5
    • 0032701914 scopus 로고    scopus 로고
    • Native and oxidized low density lipoprotein induction of tissue factor gene expression in smooth muscle cells is mediated by both Egr-1 and Sp1
    • Cui MZ, Penn MS, Chisolm GM. Native and oxidized low density lipoprotein induction of tissue factor gene expression in smooth muscle cells is mediated by both Egr-1 and Sp1. J Biol Chem 1999;274:32795-802.
    • (1999) J Biol Chem , vol.274 , pp. 32795-32802
    • Cui, M.Z.1    Penn, M.S.2    Chisolm, G.M.3
  • 9
    • 0035045084 scopus 로고    scopus 로고
    • Suppression of nuclear factor-kappa B and stimulation of inhibitor kappa B by troglitazone: Evidence for an antiinflammatory effect and a potential antiathersclerotic effect in the obese
    • Ghanim H, Garg R, Aljada A, Kumbkarni Y, Mohanty P, E. A, Hamouda W, Dandona P. Suppression of nuclear factor-kappa B and stimulation of inhibitor kappa B by troglitazone: Evidence for an antiinflammatory effect and a potential antiathersclerotic effect in the obese. J Clin Endocrinol Metab 2001;86.
    • (2001) J Clin Endocrinol Metab , vol.86
    • Ghanim, H.1    Garg, R.2    Aljada, A.3    Kumbkarni, Y.4    Mohanty, P.5    E., A.6    Hamouda, W.7    Dandona, P.8
  • 10
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear NFkB and stimulates IkB in mononuclear cells in obese subjects: Evidence for an antiinflammatory effect?
    • in press
    • Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, E. A, Ahmad S. Insulin Inhibits Intranuclear NFkB and Stimulates IkB in Mononuclear Cells in Obese Subjects: Evidence for an Antiinflammatory Effect? J Clin Endocrinol Metab 2001;in press.
    • (2001) J Clin Endocrinol Metab
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    E., A.6    Ahmad, S.7
  • 11
    • 0033959248 scopus 로고    scopus 로고
    • Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids
    • Dandona P, Karne R, Ghanim H, Hamouda W, Aljada A, Magsino CH, Jr. Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids. Circulation 2000; 101:122-4.
    • (2000) Circulation , vol.101 , pp. 122-124
    • Dandona, P.1    Karne, R.2    Ghanim, H.3    Hamouda, W.4    Aljada, A.5    Magsino C.H., Jr.6
  • 12
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 1991;19:2499.
    • (1991) Nucleic Acids Res , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 13
    • 0033237645 scopus 로고    scopus 로고
    • Increased IκB expression and diminished nuclear NFκB in human mononuclear cells following hydrocortisone injection
    • Aljada A, Ghamin H, Assian E, Mohanty P, Hamouda W, Garg R, Dandona P. Increased IκB Expression and Diminished Nuclear NFκB in Human Mononuclear Cells Following Hydrocortisone Injection. J Clin Endocrinol Metab 1999; 84:3386-89.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3386-3389
    • Aljada, A.1    Ghamin, H.2    Assian, E.3    Mohanty, P.4    Hamouda, W.5    Garg, R.6    Dandona, P.7
  • 14
    • 0035814837 scopus 로고    scopus 로고
    • Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences
    • Rauch U, Osende J, Fuster V, Badimon J, Fayad Z, Chesebro J. Thrombus formation on atherosclerotic plaques: pathogenesis and clinical consequences. Ann Intern Med 2001;134:224-238.
    • (2001) Ann Intern Med , vol.134 , pp. 224-238
    • Rauch, U.1    Osende, J.2    Fuster, V.3    Badimon, J.4    Fayad, Z.5    Chesebro, J.6
  • 15
    • 0242585716 scopus 로고    scopus 로고
    • Blood coagulation
    • Dahlback B. Blood coagulation. Lancet 2000;355:1627-32.
    • (2000) Lancet , vol.355 , pp. 1627-1632
    • Dahlback, B.1
  • 16
    • 0031756985 scopus 로고    scopus 로고
    • Tissue factor expression by monocytes: Regulation and pathophysiological roles
    • Osterud B. Tissue factor expression by monocytes: regulation and pathophysiological roles. Blood Coagul Fibrinolysis 1998;9 Suppl 1:S9-14.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , Issue.SUPPL. 1
    • Osterud, B.1
  • 17
    • 0032828231 scopus 로고    scopus 로고
    • Hypoxia/Hypoxemia-induced activation of the procoagulant pathways and the pathogenesis of ischemia-associated thrombosis
    • Yan SF, Mackman N, Kisiel W, Stern DM, Pinsky DJ. Hypoxia/Hypoxemia-induced activation of the procoagulant pathways and the pathogenesis of ischemia-associated thrombosis. Arterioscler Thromb Vasc Biol 1999;19:2029-35.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2029-2035
    • Yan, S.F.1    Mackman, N.2    Kisiel, W.3    Stern, D.M.4    Pinsky, D.J.5
  • 18
    • 0034746443 scopus 로고    scopus 로고
    • Insulin inhibits NFkB and MCP-1 expression in human aortic endothelial cells
    • Aljada A, Ghanim H, Saadeh R, Dandona P. Insulin Inhibits NFkB and MCP-1 Expression in Human Aortic Endothelial Cells. J Clin Endocrinol Metab 2001;86:450-53.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 450-453
    • Aljada, A.1    Ghanim, H.2    Saadeh, R.3    Dandona, P.4
  • 19
    • 0034456622 scopus 로고    scopus 로고
    • Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide
    • Aljada A, Saadeh R, Assian E, Ghanim H, Dandona P. Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide. J Clin Endocrinol Metab 2000;85:2572-5.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2572-2575
    • Aljada, A.1    Saadeh, R.2    Assian, E.3    Ghanim, H.4    Dandona, P.5
  • 20
    • 0033602795 scopus 로고    scopus 로고
    • Glycometabolic state at admission: Important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: Long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study
    • Malmberg K, Norhammar A, Wedel H, Ryden L. Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study. Circulation 1999;99:2626-32.
    • (1999) Circulation , vol.99 , pp. 2626-2632
    • Malmberg, K.1    Norhammar, A.2    Wedel, H.3    Ryden, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.