Expanded CAG/CTG repeat DNA induces a checkpoint response that impacts cell proliferation in Saccharomyces cerevisiae

PLoS Genetics

Volumn 7, Issue 3, 2011, Pages

  Sundararajan, Rangapriya ^a   Freudenreich, Catherine H ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 2; FUNGAL DNA; MRE11 PROTEIN; MRX COMPLEX; PROTEIN XRS2; RAD50 PROTEIN; RAD52 PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DEOXYRIBONUCLEASE; EXODEOXYRIBONUCLEASE; HYDROXYUREA; MRE11 PROTEIN, S CEREVISIAE; NUCLEIC ACID SYNTHESIS INHIBITOR; PROTEIN SERINE THREONINE KINASE; RAD53 PROTEIN, S CEREVISIAE;

ARTICLE; CAG REPEAT; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL EXPANSION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE ACTIVATION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; NONHUMAN; PEDIGREE ANALYSIS; PHENOTYPE; SACCHAROMYCES CEREVISIAE; TISSUE DEGENERATION; TRINUCLEOTIDE REPEAT; YEAST; CELL CYCLE; CYTOLOGY; DNA DAMAGE; DNA REPLICATION; GENETICS; METABOLISM;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

CELL CYCLE; CELL CYCLE PROTEINS; CELL PROLIFERATION; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; HYDROXYUREA; NUCLEIC ACID SYNTHESIS INHIBITORS; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 79953753026     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001339     Document Type: Article

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