The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

EMBO Journal

Volumn 28, Issue 8, 2009, Pages 1142-1156

  Tittel Elmer, Mireille ^a,b   Alabert, Constance ^c   Pasero, Philippe ^c   Cobb, Jennifer A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c INSTITUTE OF HUMAN GENETICS   (France)

Author keywords

DNA replication; MRX complex; Replisome stability; Sister chromatid cohesion (SCC); Stalled forks

Indexed keywords

DNA; MRE11 PROTEIN; NUCLEASE; NUCLEIC ACID BINDING PROTEIN; RAD50 PROTEIN; REPLISOME; UNCLASSIFIED DRUG; XRS2 PROTEIN;

ARTICLE; CELL CYCLE S PHASE; CELL STRESS; CELL VIABILITY; CHROMOSOME REARRANGEMENT; COMPLEX FORMATION; DNA REPLICATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SISTER CHROMATID;

ANIMALS; DNA POLYMERASE II; DNA REPLICATION; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; EPISTASIS, GENETIC; EXODEOXYRIBONUCLEASES; HUMANS; HYDROXYUREA; MULTIPROTEIN COMPLEXES; PROTEIN SYNTHESIS INHIBITORS; S PHASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 67349167663     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.60     Document Type: Article

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