-
1
-
-
21344457432
-
RNA interference: From gene silencing to gene-specific therapeutics
-
DOI 10.1016/j.pharmthera.2005.03.004, PII S0163725805000628
-
Leung RK, Whittaker PA. RNA interference: From gene silencing to gene-specific therapeutics. Pharmacol Ther 2005;8(2):222-39. This is a review paper discussing the mechanism of RNAi and the potential of siRNA being used as gene-specific therapeutics. (Pubitemid 40910042)
-
(2005)
Pharmacology and Therapeutics
, vol.107
, Issue.2
, pp. 222-239
-
-
Leung, R.K.M.1
Whittaker, P.A.2
-
3
-
-
77952500494
-
Strategies for in vivo delivery of siRNAs: Recent progress
-
This is a good review paper about the recent progress of in vivo delivery of siRNA therapeutics
-
Higuchi Y, Kawakami S, Hashida M. Strategies for in vivo delivery of siRNAs: Recent progress. BioDrugs 2010;24(3):195-205. This is a good review paper about the recent progress of in vivo delivery of siRNA therapeutics.
-
(2010)
BioDrugs
, vol.24
, Issue.3
, pp. 195-205
-
-
Higuchi, Y.1
Kawakami, S.2
Hashida, M.3
-
4
-
-
76749134014
-
Multifunctional nanocomplexes for gene transfer and gene therapy
-
Hart SL. Multifunctional nanocomplexes for gene transfer and gene therapy. Cell Biol Toxicol 2010;26(1):69-81
-
(2010)
Cell Biol Toxicol
, vol.26
, Issue.1
, pp. 69-81
-
-
Hart, S.L.1
-
5
-
-
70350780521
-
Nanoparticle-mediated gene delivery
-
Jin S, Leach JC, Ye K. Nanoparticle-mediated gene delivery. Methods Mol Biol 2009;544:547-57
-
(2009)
Methods Mol Biol
, vol.544
, pp. 547-557
-
-
Jin, S.1
Leach, J.C.2
Ye, K.3
-
6
-
-
73449101112
-
Recent trends in non-viral vector-mediated gene delivery
-
Pathak A, Patnaik S, Gupta KC. Recent trends in non-viral vector-mediated gene delivery. Biotechnol J 2009;4(11):1559-72
-
(2009)
Biotechnol J
, vol.4
, Issue.11
, pp. 1559-1572
-
-
Pathak, A.1
Patnaik, S.2
Gupta, K.C.3
-
7
-
-
70350639339
-
Strategies for short hairpin RNA delivery in cancer gene therapy
-
This is a review paper regarding possible utilization of shRNA for long-term gene silencing for cancer gene therapy
-
Wang SL, Yao HH, Qin ZH. Strategies for short hairpin RNA delivery in cancer gene therapy. Expert Opin Biol Ther 2009;9(11):1357-68. This is a review paper regarding possible utilization of shRNA for long-term gene silencing for cancer gene therapy.
-
(2009)
Expert Opin Biol Ther
, vol.9
, Issue.11
, pp. 1357-1368
-
-
Wang, S.L.1
Yao, H.H.2
Qin, Z.H.3
-
8
-
-
74049099526
-
The therapeutic potential of cell-internalizing aptamers
-
Zhou J, Rossi JJ. The therapeutic potential of cell-internalizing aptamers. Curr Top Med Chem 2009;9(12):1144-57
-
(2009)
Curr Top Med Chem
, vol.9
, Issue.12
, pp. 1144-1157
-
-
Zhou, J.1
Rossi, J.J.2
-
9
-
-
77953636470
-
Effect of nanoparticle conjugation on gene silencing by RNA interference
-
Singh N, Agrawal A, Leung AK, et al. Effect of nanoparticle conjugation on gene silencing by RNA interference. J Am Chem Soc 2010;132(24):8241-3
-
(2010)
J Am Chem Soc
, vol.132
, Issue.24
, pp. 8241-8243
-
-
Singh, N.1
Agrawal, A.2
Leung, A.K.3
-
10
-
-
77949888515
-
Electrostatic surface modifications to improve gene delivery
-
Shmueli RB, Anderson DG, Green JJ. Electrostatic surface modifications to improve gene delivery. Expert Opin Drug Deliv 2010;7(4):535-50
-
(2010)
Expert Opin Drug Deliv
, vol.7
, Issue.4
, pp. 535-550
-
-
Shmueli, R.B.1
Anderson, D.G.2
Green, J.J.3
-
11
-
-
60749099046
-
Polymer nanocarriers for the delivery of small fragments of nucleic acids: Oligonucleotides and siRNA
-
de Martimprey H, Vauthier C, Malvy C, et al. Polymer nanocarriers for the delivery of small fragments of nucleic acids: Oligonucleotides and siRNA. Eur J Pharm Biopharm 2009;71(3):490-504
-
(2009)
Eur J Pharm Biopharm
, vol.71
, Issue.3
, pp. 490-504
-
-
De Martimprey, H.1
Vauthier, C.2
Malvy, C.3
-
13
-
-
75549085405
-
Targeted drug delivery in pancreatic cancer
-
Yu X, Zhang Y, Chen C, et al. Targeted drug delivery in pancreatic cancer. Biochim Biophys Acta 2010;1805(1):97-104
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.1
, pp. 97-104
-
-
Yu, X.1
Zhang, Y.2
Chen, C.3
-
14
-
-
57749169059
-
Animal models for target diseases in gene therapy-using DNA and siRNA delivery strategies
-
This paper introduces some animal models for target diseases by using siRNA therapeutics
-
Blagbrough IS, Zara C. Animal models for target diseases in gene therapy-using DNA and siRNA delivery strategies. Pharm Res 2009;26(1):1-18. This paper introduces some animal models for target diseases by using siRNA therapeutics.
-
(2009)
Pharm Res
, vol.26
, Issue.1
, pp. 1-18
-
-
Blagbrough, I.S.1
Zara, C.2
-
15
-
-
33750043211
-
SiRNA drug delivery by biodegradable polymeric nanoparticles
-
DOI 10.1166/jnn.2006.436
-
Yuan X, Li L, Rathinavelu A, et al. SiRNA drug delivery by biodegradable polymeric nanoparticles. J Nanosci Nanotechnol 2006;6(9-10):2821-8. This is one of earliest papers reporting about siRNA silencing by polymeric nanoparticles. (Pubitemid 44579952)
-
(2006)
Journal of Nanoscience and Nanotechnology
, vol.6
, Issue.9-10
, pp. 2821-2828
-
-
Yuan, X.1
Li, N.2
Rathinavelu, A.3
Hao, J.4
Narasimhan, M.5
He, M.6
Heitlage, V.7
Tam, L.8
Viqar, S.9
Salehi, M.10
-
16
-
-
77951254207
-
Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery
-
Cun D, Foged C, Yang M, et al. Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery. Int J Pharm 2010;390(1):70-5
-
(2010)
Int J Pharm
, vol.390
, Issue.1
, pp. 70-75
-
-
Cun, D.1
Foged, C.2
Yang, M.3
-
17
-
-
70350707597
-
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
-
Patil YB, Swaminathan SK, Sadhukha T, et al. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials 2010;31(2):358-65
-
(2010)
Biomaterials
, vol.31
, Issue.2
, pp. 358-365
-
-
Patil, Y.B.1
Swaminathan, S.K.2
Sadhukha, T.3
-
18
-
-
67549130802
-
Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth
-
Braden AR, Kafka MT, Cunningham L, et al. Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth. J Nanosci Nanotechnol 2010;9(5):2856-65
-
(2010)
J Nanosci Nanotechnol
, vol.9
, Issue.5
, pp. 2856-2865
-
-
Braden, A.R.1
Kafka, M.T.2
Cunningham, L.3
-
19
-
-
66149145455
-
RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles
-
Luo G, Jin C, Long J, et al. RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles. Cancer Biol Ther 2009;8(7):594-8
-
(2009)
Cancer Biol Ther
, vol.8
, Issue.7
, pp. 594-598
-
-
Luo, G.1
Jin, C.2
Long, J.3
-
20
-
-
76749153731
-
Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
-
Jensen DM, Cun D, Maltesen MJ, et al. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. J Control Release 2010;142(1):138-45
-
(2010)
J Control Release
, vol.142
, Issue.1
, pp. 138-145
-
-
Jensen, D.M.1
Cun, D.2
Maltesen, M.J.3
-
21
-
-
77953025822
-
Surface functionalisation of PLGA nanoparticles for gene silencing
-
This paper reports on the strategies to functionalize the PLGA nanoparticles for improved gene silencing by siRNA
-
Andersen MO, Lichawska A, Arpanaei A, et al. Surface functionalisation of PLGA nanoparticles for gene silencing. Biomaterials 2010;31(21):5671-7. This paper reports on the strategies to functionalize the PLGA nanoparticles for improved gene silencing by siRNA.
-
(2010)
Biomaterials
, vol.31
, Issue.21
, pp. 5671-5677
-
-
Andersen, M.O.1
Lichawska, A.2
Arpanaei, A.3
-
22
-
-
77953616889
-
The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery
-
This paper reports the cationic chitosan-modified PLGA nanoparticles for improved delivery and enhanced gene silencing by siRNA
-
Yuan X, Shah BA, Kotadia NK, et al. The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery. Pharm Res 2010;27(7):1285-95. This paper reports the cationic chitosan-modified PLGA nanoparticles for improved delivery and enhanced gene silencing by siRNA.
-
(2010)
Pharm Res
, vol.27
, Issue.7
, pp. 1285-1295
-
-
Yuan, X.1
Shah, B.A.2
Kotadia, N.K.3
-
23
-
-
77649186723
-
Chitosan-modified poly(D,L-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects
-
Tahara K, Yamamoto H, Hirashima N, et al. Chitosan-modified poly(D,L-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects. Eur J Pharm Biopharm 2010;74(3):421-6
-
(2010)
Eur J Pharm Biopharm
, vol.74
, Issue.3
, pp. 421-426
-
-
Tahara, K.1
Yamamoto, H.2
Hirashima, N.3
-
24
-
-
84871405936
-
Controlled release of siRNA nanoparticles loaded in a novel external stent prepared by emulsion electrospinning attenuates neointima hyperplasia in vein grafts
-
Qiu XF, Dong NG, Sun ZQ, et al. Controlled release of siRNA nanoparticles loaded in a novel external stent prepared by emulsion electrospinning attenuates neointima hyperplasia in vein grafts. Zhonghua Yi Xue Za Zhi 2009;89(41):2938-42
-
(2009)
Zhonghua Yi Xue Za Zhi
, vol.89
, Issue.41
, pp. 2938-2942
-
-
Qiu, X.F.1
Dong, N.G.2
Sun, Z.Q.3
-
25
-
-
84862833394
-
Chitosan-siRNA complex nanoparticles for gene silencing
-
Liu X. Chitosan-siRNA complex nanoparticles for gene silencing. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2010;27(1):97-101
-
(2010)
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
, vol.27
, Issue.1
, pp. 97-101
-
-
Liu, X.1
-
26
-
-
85047685252
-
Cancer, chitosan nanoparticles and catalytic nucleic acids
-
Tan ML, Choong PF, Dass CR. Cancer, chitosan nanoparticles and catalytic nucleic acids. J Pharm Pharmacol 2010;61(1):3-12
-
(2010)
J Pharm Pharmacol
, vol.61
, Issue.1
, pp. 3-12
-
-
Tan, M.L.1
Choong, P.F.2
Dass, C.R.3
-
27
-
-
60949100618
-
Selection of optimal sites for TGFB1 gene silencing by chitosan-TPP nanoparticle-mediated delivery of shRNA
-
Wang SL, Yao HH, Guo LL, et al. Selection of optimal sites for TGFB1 gene silencing by chitosan-TPP nanoparticle-mediated delivery of shRNA. Cancer Genet Cytogenet 2009;190(1):8-14
-
(2009)
Cancer Genet Cytogenet
, vol.190
, Issue.1
, pp. 8-14
-
-
Wang, S.L.1
Yao, H.H.2
Guo, L.L.3
-
28
-
-
70349656993
-
Functional gene silencing mediated by chitosan/ siRNA nanocomplexes
-
Ji AM, Su D, Che O, et al. Functional gene silencing mediated by chitosan/ siRNA nanocomplexes. Nanotechnology 2009;20(40):405103
-
(2009)
Nanotechnology
, vol.20
, Issue.40
, pp. 405103
-
-
Ji, A.M.1
Su, D.2
Che, O.3
-
29
-
-
70350589264
-
Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells
-
Malhotra M, Kulamarva A, Sebak S, et al. Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells. Drug Dev Ind Pharm 2009;35(6):719-26
-
(2009)
Drug Dev Ind Pharm
, vol.35
, Issue.6
, pp. 719-726
-
-
Malhotra, M.1
Kulamarva, A.2
Sebak, S.3
-
30
-
-
70350127316
-
Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats
-
Cai YQ, Chen SR, Han HD, et al. Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats. J Neurochem 2009;111(4):1000-10
-
(2009)
J Neurochem
, vol.111
, Issue.4
, pp. 1000-1010
-
-
Cai, Y.Q.1
Chen, S.R.2
Han, H.D.3
-
31
-
-
77949270747
-
New core-shell nanoparticules for the intravenous delivery of siRNA to experimental thyroid papillary carcinoma
-
de Martimprey H, Bertrand JR, Malvy C, et al. New core-shell nanoparticules for the intravenous delivery of siRNA to experimental thyroid papillary carcinoma. Pharm Res 2010;27(3):498-509
-
(2010)
Pharm Res
, vol.27
, Issue.3
, pp. 498-509
-
-
De Martimprey, H.1
Bertrand, J.R.2
Malvy, C.3
-
32
-
-
77955113615
-
Targeted gene silencing using rgd-labeled chitosan nanoparticles
-
Hee-Dong H, Mangala LS, Lee JW, et al. Targeted gene silencing using rgd-labeled chitosan nanoparticles. Clin Cancer Res 2010;16:3910-22
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3910-3922
-
-
Hee-Dong, H.1
Mangala, L.S.2
Lee, J.W.3
-
33
-
-
70349335809
-
RNAi using a chitosan/siRNA nanoparticle system: In vitro and in vivo applications
-
Andersen MO, Howard KA, Kjems J. RNAi using a chitosan/siRNA nanoparticle system: In vitro and in vivo applications. Methods Mol Biol 2009;555:77-86
-
(2009)
Methods Mol Biol
, vol.555
, pp. 77-86
-
-
Andersen, M.O.1
Howard, K.A.2
Kjems, J.3
-
34
-
-
77954120438
-
Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA
-
Ghosn B, Singh A, Li M, et al. Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA. Oligonucleotides 2010;20(3):163-72
-
(2010)
Oligonucleotides
, vol.20
, Issue.3
, pp. 163-172
-
-
Ghosn, B.1
Singh, A.2
Li, M.3
-
35
-
-
66249133061
-
Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration
-
Glud SZ, Bramsen JB, Dagnaes-Hansen F, et al. Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. Oligonucleotides 2010;19(2):163-8
-
(2010)
Oligonucleotides
, vol.19
, Issue.2
, pp. 163-168
-
-
Glud, S.Z.1
Bramsen, J.B.2
Dagnaes-Hansen, F.3
-
36
-
-
67649865399
-
The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice
-
Gao S, Dagnaes-Hansen F, Nielsen EJ, et al. The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Mol Ther 2010;17(7):1225-33
-
(2010)
Mol Ther
, vol.17
, Issue.7
, pp. 1225-1233
-
-
Gao, S.1
Dagnaes-Hansen, F.2
Nielsen, E.J.3
-
37
-
-
58149215702
-
Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
-
Howard KA, Paludan SR, Behlke MA, et al. Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Mol Ther 2010;17(1):162-8
-
(2010)
Mol Ther
, vol.17
, Issue.1
, pp. 162-168
-
-
Howard, K.A.1
Paludan, S.R.2
Behlke, M.A.3
-
38
-
-
77449112631
-
Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro
-
Dehousse V, Garbacki N, Jaspart S, et al. Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro. Int J Biol Macromol 2010;46(3):342-9
-
(2010)
Int J Biol Macromol
, vol.46
, Issue.3
, pp. 342-349
-
-
Dehousse, V.1
Garbacki, N.2
Jaspart, S.3
-
39
-
-
73249126217
-
Development of pH-responsive nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA delivery
-
Dehousse V, Garbacki N, Colige A, et al. Development of pH-responsive nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA delivery. Biomaterials 2010;31(7):1839-49
-
(2010)
Biomaterials
, vol.31
, Issue.7
, pp. 1839-1849
-
-
Dehousse, V.1
Garbacki, N.2
Colige, A.3
-
40
-
-
69949128210
-
Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery
-
Lee DW, Yun KS, Ban HS, et al. Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery. J Control Release 2009;139(2):146-52
-
(2009)
J Control Release
, vol.139
, Issue.2
, pp. 146-152
-
-
Lee, D.W.1
Yun, K.S.2
Ban, H.S.3
-
41
-
-
77956544799
-
Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma
-
Susa M, Iyer AK, Ryu K, et al. Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS One 2010;5(5):e10764
-
(2010)
PLoS One
, vol.5
, Issue.5
-
-
Susa, M.1
Iyer, A.K.2
Ryu, K.3
-
42
-
-
67249128859
-
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
This paper reports the fist targeted delivery of siRNA in humans by cyclodextrin-based nanoparticles
-
Davis ME. The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic. Mol Pharm 2009;6(3):659-68. This paper reports the fist targeted delivery of siRNA in humans by cyclodextrin-based nanoparticles.
-
(2009)
Mol Pharm
, vol.6
, Issue.3
, pp. 659-668
-
-
Davis, M.E.1
-
43
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
This paper reports the first targeted delivery of siRNA in humans from systemically administered cyclodextrin-based and targeted nanoparticles
-
Davis ME, Zuckerman JE, Choi CH, et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010;464(7291):1067-70. This paper reports the first targeted delivery of siRNA in humans from systemically administered cyclodextrin-based and targeted nanoparticles.
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 1067-1070
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.3
-
44
-
-
67349242729
-
Delivery of RNA interference therapeutics using polycation-based nanoparticles
-
This paper reviews polycation-based nanoparticles for siRNA delivery
-
Howard KA. Delivery of RNA interference therapeutics using polycation-based nanoparticles. Adv Drug Deliv Rev 2009;61(9):710-20. This paper reviews polycation-based nanoparticles for siRNA delivery.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.9
, pp. 710-720
-
-
Howard, K.A.1
-
45
-
-
70849097385
-
Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
-
Buyens K, Meyer M, Wagner E, et al. Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy. J Control Release 2010;141(1):38-41
-
(2010)
J Control Release
, vol.141
, Issue.1
, pp. 38-41
-
-
Buyens, K.1
Meyer, M.2
Wagner, E.3
-
46
-
-
68849112640
-
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity
-
This paper reports the use of siRNA-loaded nanoparticles for cancer immunotherapy
-
Cubillos-Ruiz JR, Engle X, Scarlett UK, et al. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. J Clin Invest 2009;119(8):2231-44. This paper reports the use of siRNA-loaded nanoparticles for cancer immunotherapy.
-
(2009)
J Clin Invest
, vol.119
, Issue.8
, pp. 2231-2244
-
-
Cubillos-Ruiz, J.R.1
Engle, X.2
Scarlett, U.K.3
-
47
-
-
67349147013
-
Effect of homobifunctional crosslinkers on nucleic acids delivery ability of PEI nanoparticles
-
Swami A, Goyal R, Tripathi SK, et al. Effect of homobifunctional crosslinkers on nucleic acids delivery ability of PEI nanoparticles. Int J Pharm 2009;374(1-2):125-38
-
(2009)
Int J Pharm
, vol.374
, Issue.1-2
, pp. 125-138
-
-
Swami, A.1
Goyal, R.2
Tripathi, S.K.3
-
48
-
-
60549086379
-
In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application
-
Beyerle A, Hobel S, Czubayko F, et al. In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application. Toxicol In Vitro 2009;23(3):500-8
-
(2009)
Toxicol In Vitro
, vol.23
, Issue.3
, pp. 500-508
-
-
Beyerle, A.1
Hobel, S.2
Czubayko, F.3
-
49
-
-
72149101228
-
The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine
-
Alshamsan A, Hamdy S, Samuel J, et al. The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials 2010;31(6):1420-8
-
(2010)
Biomaterials
, vol.31
, Issue.6
, pp. 1420-1428
-
-
Alshamsan, A.1
Hamdy, S.2
Samuel, J.3
-
50
-
-
68349130528
-
Polyethylenimine nanoparticles as an efficient in vitro siRNA delivery system
-
Nimesh S, Chandra R. Polyethylenimine nanoparticles as an efficient in vitro siRNA delivery system. Eur J Pharm Biopharm 2009;73(1):43-9
-
(2009)
Eur J Pharm Biopharm
, vol.73
, Issue.1
, pp. 43-49
-
-
Nimesh, S.1
Chandra, R.2
-
51
-
-
72149100454
-
PEI-alginate nanocomposites: Efficient non-viral vectors for nucleic acids
-
Patnaik S, Arif M, Pathak A, et al. PEI-alginate nanocomposites: Efficient non-viral vectors for nucleic acids. Int J Pharm 2010;385(1-2):194-202
-
(2010)
Int J Pharm
, vol.385
, Issue.1-2
, pp. 194-202
-
-
Patnaik, S.1
Arif, M.2
Pathak, A.3
-
52
-
-
77949914688
-
Cross-linked polyethylenimine-hexametaphosphate nanoparticles to deliver nucleic acids therapeutics
-
Patnaik S, Arif M, Pathak A, et al. Cross-linked polyethylenimine- hexametaphosphate nanoparticles to deliver nucleic acids therapeutics. Nanomedicine 2010;6(2):344-54
-
(2010)
Nanomedicine
, vol.6
, Issue.2
, pp. 344-354
-
-
Patnaik, S.1
Arif, M.2
Pathak, A.3
-
53
-
-
71249151558
-
Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery
-
Philipp A, Zhao X, Tarcha P, et al. Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery. Bioconjug Chem 2009;20(11):2055-61
-
(2009)
Bioconjug Chem
, vol.20
, Issue.11
, pp. 2055-2061
-
-
Philipp, A.1
Zhao, X.2
Tarcha, P.3
-
54
-
-
77956505985
-
Reductive degradation behavior of bioreducible poly(disulfide amine) for enhancing siRNA efficiency
-
Kim SH, Ou M, Bull DA, et al. Reductive degradation behavior of bioreducible poly(disulfide amine) for enhancing siRNA efficiency. Macromol Biosci 2010;10(8):898-905
-
(2010)
Macromol Biosci
, vol.10
, Issue.8
, pp. 898-905
-
-
Kim, S.H.1
Ou, M.2
Bull, D.A.3
-
55
-
-
58249112846
-
Polymeric nanoparticles for siRNA delivery and gene silencing
-
Patil Y, Panyam J. Polymeric nanoparticles for siRNA delivery and gene silencing. Int J Pharm 2009;367(1-2):195-203
-
(2009)
Int J Pharm
, vol.367
, Issue.1-2
, pp. 195-203
-
-
Patil, Y.1
Panyam, J.2
-
56
-
-
61349137559
-
Preparation of polyethyleneimine incorporated poly(D,L-lactide- coglycolide) nanoparticles by spontaneous emulsion diffusion method for small interfering RNA delivery
-
Katas H, Cevher E, Alpar HO. Preparation of polyethyleneimine incorporated poly(D,L-lactide-coglycolide) nanoparticles by spontaneous emulsion diffusion method for small interfering RNA delivery. Int J Pharm 2009;369(1-2):144-54
-
(2009)
Int J Pharm
, vol.369
, Issue.1-2
, pp. 144-154
-
-
Katas, H.1
Cevher, E.2
Alpar, H.O.3
-
57
-
-
77952507261
-
Biodegradable nano-polymeric system for efficient Akt1 siRNA delivery
-
Jere D, Arote R, Jiang HL, et al. Biodegradable nano-polymeric system for efficient Akt1 siRNA delivery. J Nanosci Nanotechnol 2010;10(5):3366-9
-
(2010)
J Nanosci Nanotechnol
, vol.10
, Issue.5
, pp. 3366-3369
-
-
Jere, D.1
Arote, R.2
Jiang, H.L.3
-
58
-
-
58849095012
-
Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells
-
Yadav S, van Vlerken LE, Little SR, et al. Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells. Cancer Chemother Pharmacol 2009;63(4):711-22
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, Issue.4
, pp. 711-722
-
-
Yadav, S.1
Van Vlerken, L.E.2
Little, S.R.3
-
59
-
-
77951159570
-
The investigation of polymer-siRNA nanoparticle for gene therapy of gastric cancer in vitro
-
Wu Y, Wang W, Chen Y, et al. The investigation of polymer-siRNA nanoparticle for gene therapy of gastric cancer in vitro. Int J Nanomedicine 2010;5:129-36
-
(2010)
Int J Nanomedicine
, vol.5
, pp. 129-136
-
-
Wu, Y.1
Wang, W.2
Chen, Y.3
-
60
-
-
70450169244
-
Self-assembled lipid nanomedicines for siRNA tumor targeting
-
Tseng YC, Huang L. Self-assembled lipid nanomedicines for siRNA tumor targeting. J Biomed Nanotechnol 2009;5(4):351-63
-
(2009)
J Biomed Nanotechnol
, vol.5
, Issue.4
, pp. 351-363
-
-
Tseng, Y.C.1
Huang, L.2
-
61
-
-
77956265264
-
Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver
-
Tao W, Davide JP, Cai M, et al. Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver. Mol Ther 2010;18(9):1657-66
-
(2010)
Mol Ther
, vol.18
, Issue.9
, pp. 1657-1666
-
-
Tao, W.1
Davide, J.P.2
Cai, M.3
-
62
-
-
77749340522
-
Increase of the therapeutic effect by treating nasopharyngeal tumor with combination of HER-2 siRNA and paclitaxel
-
Hattori Y, Hakoshima M, Koga K, et al. Increase of the therapeutic effect by treating nasopharyngeal tumor with combination of HER-2 siRNA and paclitaxel. Int J Oncol 2010;36(4):1039-46
-
(2010)
Int J Oncol
, vol.36
, Issue.4
, pp. 1039-1046
-
-
Hattori, Y.1
Hakoshima, M.2
Koga, K.3
-
63
-
-
77955968222
-
Development of non-viral vector for cancer gene therapy
-
Hattori Y. Development of non-viral vector for cancer gene therapy. Yakugaku Zasshi 2010;130(7):917-23
-
(2010)
Yakugaku Zasshi
, vol.130
, Issue.7
, pp. 917-923
-
-
Hattori, Y.1
-
64
-
-
63149190290
-
High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis
-
Hamelers IH, Staffhorst RW, Voortman J, et al. High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis. Clin Cancer Res 2009;15(4):1259-68
-
(2009)
Clin Cancer Res
, vol.15
, Issue.4
, pp. 1259-1268
-
-
Hamelers, I.H.1
Staffhorst, R.W.2
Voortman, J.3
-
65
-
-
77952238647
-
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation
-
Akita H, Kogure K, Moriguchi R, et al. Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation. J Control Release 2010;143(3):311-17
-
(2010)
J Control Release
, vol.143
, Issue.3
, pp. 311-317
-
-
Akita, H.1
Kogure, K.2
Moriguchi, R.3
-
66
-
-
66749134637
-
Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system
-
Sakurai Y, Hatakeyama H, Akita H, et al. Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system. Biol Pharm Bull 2009;32(5):928-32
-
(2009)
Biol Pharm Bull
, vol.32
, Issue.5
, pp. 928-932
-
-
Sakurai, Y.1
Hatakeyama, H.2
Akita, H.3
-
67
-
-
57749098534
-
Efficient nucleic acid transduction with lipoplexes containing novel piperazine- and polyamine-conjugated cholesterol derivatives
-
Islam RU, Hean J, van Otterlo WA, et al. Efficient nucleic acid transduction with lipoplexes containing novel piperazine- and polyamine-conjugated cholesterol derivatives. Bioorg Med Chem Lett 2009;19(1):100-3
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.1
, pp. 100-103
-
-
Islam, R.U.1
Hean, J.2
Van Otterlo, W.A.3
-
68
-
-
57749173422
-
Very long chain N4, N9-diacyl spermines: Non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery
-
Ghonaim HM, Li S, Blagbrough IS. Very long chain N4, N9-diacyl spermines: Non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery. Pharm Res 2009;26(1):19-31
-
(2009)
Pharm Res
, vol.26
, Issue.1
, pp. 19-31
-
-
Ghonaim, H.M.1
Li, S.2
Blagbrough, I.S.3
-
69
-
-
72949086404
-
N1 N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation
-
Ghonaim HM, Li S, Blagbrough IS. N1, N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation. Pharm Res 2010;27(1):17-29
-
(2010)
Pharm Res
, vol.27
, Issue.1
, pp. 17-29
-
-
Ghonaim, H.M.1
Li, S.2
Blagbrough, I.S.3
-
70
-
-
77951066315
-
Nucleic acid transfer with hemifluorinated polycationic lipids
-
Klein E, Leborgne C, Ciobanu M, et al. Nucleic acid transfer with hemifluorinated polycationic lipids. Biomaterials 2010;31(17):4781-8
-
(2010)
Biomaterials
, vol.31
, Issue.17
, pp. 4781-4718
-
-
Klein, E.1
Leborgne, C.2
Ciobanu, M.3
-
71
-
-
69949168026
-
Drug delivery-mediated control of RNA immunostimulation
-
Nguyen DN, Chen SC, Lu J, et al. Drug delivery-mediated control of RNA immunostimulation. Mol Ther 2009;17(9):1555-62
-
(2009)
Mol Ther
, vol.17
, Issue.9
, pp. 1555-1562
-
-
Nguyen, D.N.1
Chen, S.C.2
Lu, J.3
-
72
-
-
77950368673
-
DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA
-
Mevel M, Kamaly N, Carmona S, et al. DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA. J Control Release 2010;143(2):222-32
-
(2010)
J Control Release
, vol.143
, Issue.2
, pp. 222-232
-
-
Mevel, M.1
Kamaly, N.2
Carmona, S.3
-
73
-
-
68549130637
-
Chemical vectors for gene delivery: A current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers
-
Midoux P, Pichon C, Yaouanc JJ, et al. Chemical vectors for gene delivery: A current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. Br J Pharmacol 2009;157(2):166-78
-
(2009)
Br J Pharmacol
, vol.157
, Issue.2
, pp. 166-178
-
-
Midoux, P.1
Pichon, C.2
Yaouanc, J.J.3
-
74
-
-
77953360479
-
Delivery of DNA and siRNA by novel gemini-like amphiphilic peptides
-
Damen M, Aarbiou J, van Dongen SF, et al. Delivery of DNA and siRNA by novel gemini-like amphiphilic peptides. J Control Release 2010;145(1):33-9
-
(2010)
J Control Release
, vol.145
, Issue.1
, pp. 33-39
-
-
Damen, M.1
Aarbiou, J.2
Van Dongen, S.F.3
-
75
-
-
71949099757
-
Lipid-based nanotherapeutics for siRNA delivery
-
Schroeder A, Levins CG, Cortez C, et al. Lipid-based nanotherapeutics for siRNA delivery. J Intern Med 2010;267(1):9-21
-
(2010)
J Intern Med
, vol.267
, Issue.1
, pp. 9-21
-
-
Schroeder, A.1
Levins, C.G.2
Cortez, C.3
-
76
-
-
70350142394
-
An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation
-
Huang Z, King MR. An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation. Gene Ther 2009;16(10):1271-82
-
(2009)
Gene Ther
, vol.16
, Issue.10
, pp. 1271-1282
-
-
Huang, Z.1
King, M.R.2
-
77
-
-
84934435712
-
Systemic delivery and pre-clinical evaluation of nanoparticles containing antisense oligonucleotides and siRNAs
-
Zhang C, Newsome JT, Mewani R, et al. Systemic delivery and pre-clinical evaluation of nanoparticles containing antisense oligonucleotides and siRNAs. Methods Mol Biol 2009;480:65-83
-
(2009)
Methods Mol Biol
, vol.480
, pp. 65-83
-
-
Zhang, C.1
Newsome, J.T.2
Mewani, R.3
-
78
-
-
71949092463
-
Nanomedicine based approaches for the delivery of siRNA in cancer
-
This paper reviews the use of nanomedicine for the delivery of siRNA to cancer
-
Ozpolat B, Sood AK, Lopez-Berestein G. Nanomedicine based approaches for the delivery of siRNA in cancer. J Intern Med 2010;267(1):44-53. This paper reviews the use of nanomedicine for the delivery of siRNA to cancer.
-
(2010)
J Intern Med
, vol.267
, Issue.1
, pp. 44-53
-
-
Ozpolat, B.1
Sood, A.K.2
Lopez-Berestein, G.3
-
79
-
-
70349542520
-
Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer
-
Li SD, Huang L. Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer. Biochim Biophys Acta 2009;1788(10):2259-66
-
(2009)
Biochim Biophys Acta
, vol.1788
, Issue.10
, pp. 2259-2266
-
-
Li, S.D.1
Huang, L.2
-
80
-
-
77954599597
-
Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer
-
Chen Y, Bathula SR, Li J, et al. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. J Biol Chem 2010;285(29):22639-50
-
(2010)
J Biol Chem
, vol.285
, Issue.29
, pp. 22639-22650
-
-
Chen, Y.1
Bathula, S.R.2
Li, J.3
-
81
-
-
77956269093
-
Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
-
Chen Y, Zhu X, Zhang X, et al. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol Ther 2010;18(9):1650-6
-
(2010)
Mol Ther
, vol.18
, Issue.9
, pp. 1650-1656
-
-
Chen, Y.1
Zhu, X.2
Zhang, X.3
-
82
-
-
69249150822
-
A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo
-
Yagi N, Manabe I, Tottori T, et al. A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo. Cancer Res 2009;69(16):6531-8
-
(2009)
Cancer Res
, vol.69
, Issue.16
, pp. 6531-6538
-
-
Yagi, N.1
Manabe, I.2
Tottori, T.3
-
83
-
-
59349118475
-
Targeted delivery of siRNA against hepatitis C virus by apolipoprotein A-I-bound cationic liposomes
-
Kim SI, Shin D, Lee H, et al. Targeted delivery of siRNA against hepatitis C virus by apolipoprotein A-I-bound cationic liposomes. J Hepatol 2009;50(3):479-88
-
(2009)
J Hepatol
, vol.50
, Issue.3
, pp. 479-488
-
-
Kim, S.I.1
Shin, D.2
Lee, H.3
-
84
-
-
66249083866
-
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
-
Woodrow KA, Cu Y, Booth CJ, et al. Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat Mater 2009;8(6):526-33
-
(2009)
Nat Mater
, vol.8
, Issue.6
, pp. 526-533
-
-
Woodrow, K.A.1
Cu, Y.2
Booth, C.J.3
-
85
-
-
77951122502
-
Knocking down gene expression with dendritic vectors
-
Ravina M, Paolicelli P, Seijo B, et al. Knocking down gene expression with dendritic vectors. Mini Rev Med Chem 2010;10(1):73-86
-
(2010)
Mini Rev Med Chem
, vol.10
, Issue.1
, pp. 73-86
-
-
Ravina, M.1
Paolicelli, P.2
Seijo, B.3
-
86
-
-
77749280012
-
Ability to adapt: Different generations of PAMAM dendrimers show different behaviors in binding siRNA
-
This paper discusses interaction of siRNA with different generations of PAMAM dendrimers
-
Pavan GM, Albertazzi L, Danani A. Ability to adapt: Different generations of PAMAM dendrimers show different behaviors in binding siRNA. J Phys Chem B 2010;114(8):2667-75. This paper discusses interaction of siRNA with different generations of PAMAM dendrimers.
-
(2010)
J Phys Chem B
, vol.114
, Issue.8
, pp. 2667-2675
-
-
Pavan, G.M.1
Albertazzi, L.2
Danani, A.3
-
87
-
-
77953471152
-
LHRH-targeted nanoparticles for cancer therapeutics
-
Minko T, Patil ML, Zhang M, et al. LHRH-targeted nanoparticles for cancer therapeutics. Methods Mol Biol 2010;624:281-94
-
(2010)
Methods Mol Biol
, vol.624
, pp. 281-294
-
-
Minko, T.1
Patil, M.L.2
Zhang, M.3
-
88
-
-
64149113037
-
Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: Effect of the degree of quaternization and cancer targeting
-
Patil ML, Zhang M, Taratula O, et al. Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: Effect of the degree of quaternization and cancer targeting. Biomacromolecules 2009;10(2):258-66
-
(2009)
Biomacromolecules
, vol.10
, Issue.2
, pp. 258-626
-
-
Patil, M.L.1
Zhang, M.2
Taratula, O.3
-
89
-
-
65549120153
-
Acetylation of PAMAM dendrimers for cellular delivery of siRNA
-
Waite CL, Sparks SM, Uhrich KE, et al. Acetylation of PAMAM dendrimers for cellular delivery of siRNA. BMC Biotechnol 2009;9:38
-
(2009)
BMC Biotechnol
, vol.9
, pp. 38
-
-
Waite, C.L.1
Sparks, S.M.2
Uhrich, K.E.3
-
90
-
-
77953542134
-
Dynamic contrast-enhanced folate-receptor-targeted MR imaging using a Gd-loaded PEG-dendrimer-folate conjugate in a mouse xenograft tumor model
-
Chen WT, Thirumalai D, Shih TT, et al. Dynamic contrast-enhanced folate-receptor-targeted MR imaging using a Gd-loaded PEG-dendrimer-folate conjugate in a mouse xenograft tumor model. Mol Imaging Biol 2010;12(2):145-54
-
(2010)
Mol Imaging Biol
, vol.12
, Issue.2
, pp. 145-154
-
-
Chen, W.T.1
Thirumalai, D.2
Shih, T.T.3
-
91
-
-
69549086354
-
Ethylendiamine core PAMAM dendrimers/siRNA complexes as in vitro silencing agents
-
Perez AP, Romero EL, Morilla MJ. Ethylendiamine core PAMAM dendrimers/siRNA complexes as in vitro silencing agents. Int J Pharm 2009;380(1-2):189-200
-
(2009)
Int J Pharm
, vol.380
, Issue.1-2
, pp. 189-200
-
-
Perez, A.P.1
Romero, E.L.2
Morilla, M.J.3
-
92
-
-
68149163646
-
PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells
-
Liu XX, Rocchi P, Qu FQ, et al. PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells. ChemMedChem 2009;4(8):1302-10
-
(2009)
ChemMedChem
, vol.4
, Issue.8
, pp. 1302-1310
-
-
Liu, X.X.1
Rocchi, P.2
Qu, F.Q.3
-
93
-
-
70449700090
-
Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
-
Taratula O, Garbuzenko OB, Kirkpatrick P, et al. Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery. J Control Release 2009;140(3):284-93
-
(2009)
J Control Release
, vol.140
, Issue.3
, pp. 284-293
-
-
Taratula, O.1
Garbuzenko, O.B.2
Kirkpatrick, P.3
-
94
-
-
63949086284
-
Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity
-
Posadas I, Lopez-Hernandez B, Clemente MI, et al. Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity. Pharm Res 2009;26(5):1181-91
-
(2009)
Pharm Res
, vol.26
, Issue.5
, pp. 1181-1191
-
-
Posadas, I.1
Lopez-Hernandez, B.2
Clemente, M.I.3
-
95
-
-
60049085119
-
Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16
-
Gras R, Almonacid L, Ortega P, et al. Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16. Pharm Res 2009;26(3):577-86
-
(2009)
Pharm Res
, vol.26
, Issue.3
, pp. 577-586
-
-
Gras, R.1
Almonacid, L.2
Ortega, P.3
-
96
-
-
70349551739
-
Functional delivery of siRNA in mice using dendriworms
-
Agrawal A, Min DH, Singh N, et al. Functional delivery of siRNA in mice using dendriworms. ACS Nano 2009;3(9):2495-504
-
(2009)
ACS Nano
, vol.3
, Issue.9
, pp. 2495-2504
-
-
Agrawal, A.1
Min, D.H.2
Singh, N.3
-
97
-
-
77950948806
-
Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo
-
Han L, Zhang A, Wang H, et al. Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo. Hum Gene Ther 2010;21(4):417-26
-
(2010)
Hum Gene Ther
, vol.21
, Issue.4
, pp. 417-426
-
-
Han, L.1
Zhang, A.2
Wang, H.3
-
98
-
-
78650847411
-
First evidence of RNA interference mechanism induced in human: Getting closer to a cure?
-
[Epub ahead of print] This paper discusses the significance of the first RNAi mechanism induced in humans
-
Roth L. First evidence of RNA interference mechanism induced in human: Getting closer to a cure? Cell Adh Migr 2011 [Epub ahead of print] This paper discusses the significance of the first RNAi mechanism induced in humans.
-
(2011)
Cell Adh Migr
-
-
Roth, L.1
-
99
-
-
77953287724
-
Clinical status of duplex RNA
-
Watts JK, Corey DR. Clinical status of duplex RNA. Bioorg Med Chem Lett 2010;20(11):3203-7
-
(2010)
Bioorg Med Chem Lett
, vol.20
, Issue.11
, pp. 3203-3207
-
-
Watts, J.K.1
Corey, D.R.2
-
100
-
-
77958135080
-
RNA interference advances to early-stage clinical trials
-
This paper reports the current status of clinical trials of several siRNA products
-
Brower V. RNA interference advances to early-stage clinical trials. J Natl Cancer Inst 2010;102(19):1459-61. This paper reports the current status of clinical trials of several siRNA products.
-
(2010)
J Natl Cancer Inst
, vol.102
, Issue.19
, pp. 1459-1461
-
-
Brower, V.1
|