Drug delivery-mediated control of RNA immunostimulation

Molecular Therapy

Volumn 17, Issue 9, 2009, Pages 1555-1562

  Nguyen, David N ^a   Chen, Steve C Y ^a   Lu, James ^a   Goldberg, Michael ^a   Kim, Phillip ^a,b   Sprague, Andrew ^c   Novobrantseva, Tatiana ^c   Sherman, Jennifer ^c   Shulga Morskaya, Svetlana ^c   de Fougerolles, Antonin ^c   Chen, Jianzhu ^a   Langer, Robert ^a,b   Anderson, Daniel G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; GENE ACTIVATION; GENE ACTIVITY; GENE TARGETING; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFLUENZA VIRUS A; INNATE IMMUNITY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHARMACOLOGICAL BLOCKING; RNA INTERFERENCE; RNA SEQUENCE; SEQUENCE HOMOLOGY; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; HUMANS; IMMUNIZATION; INFLUENZA A VIRUS; MALE; MICE; NANOPARTICLES; ORTHOMYXOVIRIDAE INFECTIONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTORS; VERO CELLS; VIRUS REPLICATION;

INFLUENZA A VIRUS;

EID: 69949168026     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.147     Document Type: Article

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