Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery

Bioconjugate Chemistry

Volumn 20, Issue 11, 2009, Pages 2055-2061

  Philipp, Alexander ^a   Zhao, Xiaobin ^b   Tarcha, Peter ^b   Wagner, Ernst ^a   Zintchenko, Arkadi ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b ABBOTT LABORATORIES   (United States)

^c UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; BIOCOMPATIBILITY; CELL MEMBRANES; DISEASES; STRUCTURAL OPTIMIZATION;

'CURRENT; DELIVERY VEHICLE; LOW MOLECULAR WEIGHT; MICHAEL ADDITIONS; POLYMERIC DELIVERY; POLYPLEXES; RNA INTERFERENCE; SIRNA DELIVERY; THERAPEUTIC STRATEGY; TRANSFECTION AGENTS;

RNA;

ACRYLIC ACID DERIVATIVE; ACRYLIC ACID HEXYL ESTER; DRUG VEHICLE; LAURYL ACRYLATE; LUCIFERASE; NANOPARTICLE; OLIGOETHYLENIMINE DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOCOMPATIBILITY; BIODEGRADATION; CELL MEMBRANE; CELL VIABILITY; CHEMICAL BOND; COLLOID; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; DRUG STABILITY; ENZYME ACTIVITY; GENE DELIVERY SYSTEM; GENE SILENCING; GENETIC TRANSFECTION; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; MACROMOLECULE; MICHAEL ADDITION; MOLECULAR WEIGHT; NEOPLASM; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; RNA INTERFERENCE; ZETA POTENTIAL;

EID: 71249151558     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9001536     Document Type: Article

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