Delivery of DNA and siRNA by novel gemini-like amphiphilic peptides

Journal of Controlled Release

Volumn 145, Issue 1, 2010, Pages 33-39

  Damen, Mark ^a   Aarbiou, Jamil ^b   van Dongen, Stijn F M ^b   Buijs Offerman, Ruvalic M ^b   Spijkers, Patricia P ^b   van den Heuvel, Maaike ^a   Kvashnina, Kristina ^c   Nolte, Roeland J M ^a   Scholte, Bob J ^b   Feiters, Martin C ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

Author keywords

Geminoid; Gene transfection; Lipopeptide; Lipoplex; RNA interference

Indexed keywords

AMPHIPHILICS; BINDING MOTIF; BIOLOGICAL ACTIVITIES; CYTOTOXIC EFFECTS; GENE TRANSFECTION; HEXAGONAL PACKING; LIPOPEPTIDES; LIPOPLEXES; RNA INTERFERENCE; SIRNA DELIVERY;

DNA; DRUG THERAPY; GENES; HYDROCARBONS; NUCLEIC ACIDS; PEPTIDES;

RNA;

DNA; LIPOPEPTIDE; LIPOPLEX; NANOPARTICLE; SMALL INTERFERING RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENDOCYTOSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTON NUCLEAR MAGNETIC RESONANCE; RNA INTERFERENCE; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; ANIMALS; CATIONS; DNA; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPIDS; LIPOSOMES; MODELS, MOLECULAR; NANOPARTICLES; OLEIC ACIDS; OLIGOPEPTIDES; PARTICLE SIZE; PLASMIDS; RNA, SMALL INTERFERING; SALMON; SCATTERING, SMALL ANGLE; SURFACE-ACTIVE AGENTS; TRANSFECTION; X-RAY DIFFRACTION;

EID: 77953360479     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.03.028     Document Type: Article

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