N1,N12-diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation

Pharmaceutical Research

Volumn 27, Issue 1, 2010, Pages 17-29

  Ghonaim, Hassan M ^a   Li, Shi ^a   Blagbrough, Ian S ^a  

^a University of Bath   (United Kingdom)

Author keywords

Gene delivery; Primary skin cells; SiRNA delivery; Transfection; TransIT TKO

Indexed keywords

AMINE; ENHANCED GREEN FLUORESCENT PROTEIN; ETHIDIUM BROMIDE; FLUORESCEIN; LIPOGEN; LIPOPOLYAMINE; LIPOSOME; LIPOSPERMINE; N 1,N 12 DIACYL SPERMINE DERIVATIVE; N 1,N 12 DIDECANOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N 1,N 12 DIMYRISTOLEOY 1,12 DIAMINO 4,9 DIAZADODECANE; N 1,N 12 DIMYRISTOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N 1,N 12 DIOLEOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N 1,N 12 DISTEAROYL 1,12 DIAMINO 4,9 DIAZADODECANE; NANOPARTICLE; NUCLEASE; NUCLEOTIDE; PLASMID DNA; SMALL INTERFERING RNA; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS VECTOR; DNA; DRUG CARRIER; DRUG DERIVATIVE; POLYAMINE; SPERMINE;

ACYLATION; ARTICLE; CELL IMMORTALIZATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA TRANSFECTION; DRUG FORMULATION; DRUG STRUCTURE; ENDOCYTOSIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; RNA BINDING; SKIN CELL; STRUCTURE ACTIVITY RELATION; SYNTHESIS; BIOLOGICAL MODEL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; METHODOLOGY; PLASMID; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DNA; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; PLASMIDS; POLYAMINES; RNA, SMALL INTERFERING; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 72949086404     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9764-3     Document Type: Article

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