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Volumn 26, Issue 1, 2009, Pages 19-31

Very long chain N4, N9-diacyl spermines: Non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery

Author keywords

Erucic acid; N4, N9 dioleoyl spermine; Primary skin cells; siRNA delivery; Very long chain fatty acid

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; N4,N9 DIACYLSPERMINE DERIVATIVE; N4,N9 DIARACHIDONOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N4,N9 DIARACHIDOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N4,N9 DIEICOSENOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N4,N9 DIERUCOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N4,N9 DINERVONOYL 1,12 DIAMINO 4,9 DIAZADODECANE; N4,N9 DIOLEOYL 1,12 DIAMINO 4,9 DIAZADODECANE; NANOPARTICLE; PLASMID DNA; SMALL INTERFERING RNA; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID; DNA; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; ETHIDIUM; FATTY ACID; FLUORESCENT DYE; GREEN FLUORESCENT PROTEIN; LIPOSOME; SPERMINE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

EID: 57749173422     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9705-1     Document Type: Article
Times cited : (13)

References (70)
  • 1
    • 33847099637 scopus 로고    scopus 로고
    • Lipid-based nanoparticles for nucleic acid delivery
    • W. J. Li F. C. Szoka 2007 Lipid-based nanoparticles for nucleic acid delivery Pharm. Res. 24 438 449
    • (2007) Pharm. Res. , vol.24 , pp. 438-449
    • Li, W.J.1    Szoka, F.C.2
  • 3
    • 32244431760 scopus 로고    scopus 로고
    • 9 -dioctadecanoyl spermines: Nonviral lipopolyamine vectors for more efficient plasmid DNA formulation
    • 9 -dioctadecanoyl spermines: Nonviral lipopolyamine vectors for more efficient plasmid DNA formulation Pharm. Res. 23 31 40
    • (2006) Pharm. Res. , vol.23 , pp. 31-40
    • Ahmed, O.A.A.1    Pourzand, C.2    Blagbrough, I.S.3
  • 4
    • 34247181222 scopus 로고    scopus 로고
    • Gene delivery by cationic lipid vectors: Overcoming cellular barriers
    • I. S. Zuhorn J. B. F. N. Engberts D. Hoekstra 2007 Gene delivery by cationic lipid vectors: overcoming cellular barriers Eur. Biophys. J. Biophys. 36 349 362
    • (2007) Eur. Biophys. J. Biophys. , vol.36 , pp. 349-362
    • Zuhorn, I.S.1    Engberts, J.B.F.N.2    Hoekstra, D.3
  • 5
    • 33847194591 scopus 로고    scopus 로고
    • Transcriptionally targeted nonviral gene transfer using a β-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells
    • L. Gaedtke J. Pelisek K. S. Lipinski C. J. Wrighton E. Wagner 2007 Transcriptionally targeted nonviral gene transfer using a β-catenin/TCF- dependent promoter in a series of different human low passage colon cancer cells Mol. Pharm. 4 129 139
    • (2007) Mol. Pharm. , vol.4 , pp. 129-139
    • Gaedtke, L.1    Pelisek, J.2    Lipinski, K.S.3    Wrighton, C.J.4    Wagner, E.5
  • 7
    • 33751005847 scopus 로고    scopus 로고
    • DNA condensation and cell transfection properties of guanidinium calixarenes: Dependence on macrocycle lipophilicity, size, and conformation
    • F. Sansone M. Dudic G. Donofrio C. Rivetti L. Baldini A. Casnati S. Cellai R. Ungaro 2006 DNA condensation and cell transfection properties of guanidinium calixarenes: Dependence on macrocycle lipophilicity, size, and conformation J. Am. Chem. Soc. 128 14528 14536
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 14528-14536
    • Sansone, F.1    Dudic, M.2    Donofrio, G.3    Rivetti, C.4    Baldini, L.5    Casnati, A.6    Cellai, S.7    Ungaro, R.8
  • 8
    • 33646892850 scopus 로고    scopus 로고
    • Chitosan-modified dry powder formulations for pulmonary gene delivery
    • H. Y. Li J. Birchall 2006 Chitosan-modified dry powder formulations for pulmonary gene delivery Pharm. Res. 23 941 950
    • (2006) Pharm. Res. , vol.23 , pp. 941-950
    • Li, H.Y.1    Birchall, J.2
  • 9
    • 0028501007 scopus 로고
    • Gene-transfer with synthetic cationic amphiphiles-prospects for gene-therapy
    • J. P. Behr 1994 Gene-transfer with synthetic cationic amphiphiles-prospects for gene-therapy Bioconjug. Chem. 5 382 389
    • (1994) Bioconjug. Chem. , vol.5 , pp. 382-389
    • Behr, J.P.1
  • 10
    • 33748290173 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Non-viral gene therapy by systemic delivery
    • S. D. Li L. Huang 2006 Gene therapy progress and prospects: non-viral gene therapy by systemic delivery Gene Ther. 13 1313 1319
    • (2006) Gene Ther. , vol.13 , pp. 1313-1319
    • Li, S.D.1    Huang, L.2
  • 12
    • 34347342795 scopus 로고    scopus 로고
    • Gene-based therapy for hypertension do preclinical data suggest a promising future?
    • G. M. Puddu E. Cravero E. Ferrari A. Muscari P. Puddu 2007 Gene-based therapy for hypertension do preclinical data suggest a promising future? Cardiology 108 40 47
    • (2007) Cardiology , vol.108 , pp. 40-47
    • Puddu, G.M.1    Cravero, E.2    Ferrari, E.3    Muscari, A.4    Puddu, P.5
  • 13
    • 33645500266 scopus 로고    scopus 로고
    • Progress towards in vivo use of siRNAs
    • M. A. Behlke 2006 Progress towards in vivo use of siRNAs Mol. Ther. 13 644 670
    • (2006) Mol. Ther. , vol.13 , pp. 644-670
    • Behlke, M.A.1
  • 15
    • 33746931297 scopus 로고    scopus 로고
    • Ligand-targeted delivery of therapeutic siRNA
    • Y. Ikeda K. Taira 2006 Ligand-targeted delivery of therapeutic siRNA Pharm. Res. 23 1631 1640
    • (2006) Pharm. Res. , vol.23 , pp. 1631-1640
    • Ikeda, Y.1    Taira, K.2
  • 17
    • 33746871416 scopus 로고    scopus 로고
    • Can siRNA technology provide the tools for gene therapy of the future?
    • Z. Racz P. Hamar 2006 Can siRNA technology provide the tools for gene therapy of the future? Curr. Med. Chem. 13 2299 2307
    • (2006) Curr. Med. Chem. , vol.13 , pp. 2299-2307
    • Racz, Z.1    Hamar, P.2
  • 18
    • 37049003720 scopus 로고    scopus 로고
    • Polycation-based nanoparticle delivery for improved RNA interference therapeutics
    • K. A. Howard J. Kjems 2007 Polycation-based nanoparticle delivery for improved RNA interference therapeutics Expert Opin. Biol. Ther. 7 1811 1822
    • (2007) Expert Opin. Biol. Ther. , vol.7 , pp. 1811-1822
    • Howard, K.A.1    Kjems, J.2
  • 19
    • 36649030332 scopus 로고    scopus 로고
    • Delivery of large biopharmaceuticals from cardiovascular stents: A review
    • H. Takahashi D. Letourneur D. W. Grainger 2007 Delivery of large biopharmaceuticals from cardiovascular stents: A review Biomacromolecules 8 3281 3293
    • (2007) Biomacromolecules , vol.8 , pp. 3281-3293
    • Takahashi, H.1    Letourneur, D.2    Grainger, D.W.3
  • 20
    • 34548818764 scopus 로고    scopus 로고
    • Cationic lipids and polymers mediated vectors for delivery of siRNA
    • S. B. Zhang B. Zhao H. M. Jiang B. Wang B. C. Ma 2007 Cationic lipids and polymers mediated vectors for delivery of siRNA J. Control. Release 123 1 10
    • (2007) J. Control. Release , vol.123 , pp. 1-10
    • Zhang, S.B.1    Zhao, B.2    Jiang, H.M.3    Wang, B.4    Ma, B.C.5
  • 21
    • 39549117983 scopus 로고    scopus 로고
    • Delivery vehicles for small interfering RNA in vivo
    • A. R. De Fougerolles 2008 Delivery vehicles for small interfering RNA in vivo Hum. Gene Ther. 19 125 132
    • (2008) Hum. Gene Ther. , vol.19 , pp. 125-132
    • De Fougerolles, A.R.1
  • 22
    • 40449083756 scopus 로고    scopus 로고
    • Targeted delivery of small interfering RNA: Approaching effective cancer therapies
    • K. F. Pirollo E. H. Chang 2008 Targeted delivery of small interfering RNA: Approaching effective cancer therapies Cancer Res. 68 1247 1250
    • (2008) Cancer Res. , vol.68 , pp. 1247-1250
    • Pirollo, K.F.1    Chang, E.H.2
  • 24
    • 34249077607 scopus 로고    scopus 로고
    • Cell and tissue targeting of nucleic acids for cancer gene therapy
    • V. Russ E. Wagner 2007 Cell and tissue targeting of nucleic acids for cancer gene therapy Pharm. Res. 24 1047 1057
    • (2007) Pharm. Res. , vol.24 , pp. 1047-1057
    • Russ, V.1    Wagner, E.2
  • 25
    • 34247647106 scopus 로고    scopus 로고
    • Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis
    • K. Morimoto M. Kondo K. Kawahara H. Ushijima Y. Tomino M. Miyajima J. Kimura 2007 Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis Pharm. Res. 24 946 954
    • (2007) Pharm. Res. , vol.24 , pp. 946-954
    • Morimoto, K.1    Kondo, M.2    Kawahara, K.3    Ushijima, H.4    Tomino, Y.5    Miyajima, M.6    Kimura, J.7
  • 28
    • 33846167801 scopus 로고    scopus 로고
    • Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: Implications for cancer gene therapy
    • M. Walsh M. Tangney M. O'Neill J. Larkin D. Soden S. McKenna R. Darcy G. O'Sullivan C. O'Driscoll 2006 Evaluation of cellular uptake and gene transfer efficiency of pegylated poly-L-lysine compacted DNA: Implications for cancer gene therapy Mol. Pharm. 3 644 653
    • (2006) Mol. Pharm. , vol.3 , pp. 644-653
    • Walsh, M.1    Tangney, M.2    O'Neill, M.3    Larkin, J.4    Soden, D.5    McKenna, S.6    Darcy, R.7    O'Sullivan, G.8    O'Driscoll, C.9
  • 29
    • 34249108022 scopus 로고    scopus 로고
    • Intracellular kinetics of non-viral gene delivery using polyethylenimine carriers
    • J. Y. Zhou J. W. Yockman S. W. Kim S. E. Kern 2007 Intracellular kinetics of non-viral gene delivery using polyethylenimine carriers Pharm. Res. 24 1079 1087
    • (2007) Pharm. Res. , vol.24 , pp. 1079-1087
    • Zhou, J.Y.1    Yockman, J.W.2    Kim, S.W.3    Kern, S.E.4
  • 31
    • 0034214275 scopus 로고    scopus 로고
    • Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy
    • A. J. Geall I. S. Blagbrough 2000 Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy J. Pharm. Biomed. Anal. 22 849 859
    • (2000) J. Pharm. Biomed. Anal. , vol.22 , pp. 849-859
    • Geall, A.J.1    Blagbrough, I.S.2
  • 32
    • 0000893449 scopus 로고
    • Efficient gene-transfer into mammalian primary endocrine-cells with lipopolyamine-coated DNA
    • J. P. Behr B. Demeneix J. P. Loeffler J. P. Mutul 1989 Efficient gene-transfer into mammalian primary endocrine-cells with lipopolyamine-coated DNA Proc. Natl. Acad. Sci. U. S. A. 86 6982 6986
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 6982-6986
    • Behr, J.P.1    Demeneix, B.2    Loeffler, J.P.3    Mutul, J.P.4
  • 33
    • 0028535425 scopus 로고
    • Gene-transfer with a series of lipophilic DNA-binding molecules
    • J. S. Remy C. Sirlin P. Vierling J. P. Behr 1994 Gene-transfer with a series of lipophilic DNA-binding molecules Bioconjug. Chem. 5 647 654
    • (1994) Bioconjug. Chem. , vol.5 , pp. 647-654
    • Remy, J.S.1    Sirlin, C.2    Vierling, P.3    Behr, J.P.4
  • 37
    • 0022516835 scopus 로고
    • Quantitative differences in host-cell reactivation of ultraviolet-damaged virus in human-skin fibroblasts and epidermal-keratinocytes cultured from the same foreskin biopsy
    • R. M. Tyrrell M. Pidoux 1986 Quantitative differences in host-cell reactivation of ultraviolet-damaged virus in human-skin fibroblasts and epidermal-keratinocytes cultured from the same foreskin biopsy Cancer Res. 46 2665 2669
    • (1986) Cancer Res. , vol.46 , pp. 2665-2669
    • Tyrrell, R.M.1    Pidoux, M.2
  • 38
    • 0026720075 scopus 로고
    • Tight control of gene-expression in mammalian-cells by tetracycline-responsive promoters
    • M. Gossen H. Bujard 1992 Tight control of gene-expression in mammalian-cells by tetracycline-responsive promoters Proc. Natl. Acad. Sci. U. S. A. 89 5547 5551
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 39
    • 0038004448 scopus 로고    scopus 로고
    • A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity
    • D. Fischer T. Bieber Y. X. Li H. P. Elsasser T. Kissel 1999 A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity Pharm. Res. 16 1273 1279
    • (1999) Pharm. Res. , vol.16 , pp. 1273-1279
    • Fischer, D.1    Bieber, T.2    Li, Y.X.3    Elsasser, H.P.4    Kissel, T.5
  • 40
    • 0029044308 scopus 로고
    • A one-step procedure for the selective trifluoroacetylation of primary amino-groups of polyamines
    • M. C. O'Sullivan D. M. Dalrymple 1995 A one-step procedure for the selective trifluoroacetylation of primary amino-groups of polyamines Tetrahedron Lett. 36 3451 3452
    • (1995) Tetrahedron Lett. , vol.36 , pp. 3451-3452
    • O'Sullivan, M.C.1    Dalrymple, D.M.2
  • 41
    • 0029130012 scopus 로고
    • Ethyl trifluoroacetate - A powerful reagent for differentiating amino-groups
    • D. Xu K. Prasad O. Repic T. J. Blacklock 1995 Ethyl trifluoroacetate - a powerful reagent for differentiating amino-groups Tetrahedron Lett. 36 7357 7360
    • (1995) Tetrahedron Lett. , vol.36 , pp. 7357-7360
    • Xu, D.1    Prasad, K.2    Repic, O.3    Blacklock, T.J.4
  • 42
    • 0034647016 scopus 로고    scopus 로고
    • Homologation of polyamines in the rapid synthesis of lipospermine conjugates and related lipoplexes
    • A. J. Geall I. S. Blagbrough 2000 Homologation of polyamines in the rapid synthesis of lipospermine conjugates and related lipoplexes Tetrahedron 56 2449 2460
    • (2000) Tetrahedron , vol.56 , pp. 2449-2460
    • Geall, A.J.1    Blagbrough, I.S.2
  • 43
    • 0023220536 scopus 로고
    • Total synthesis of (±)-15-deoxyspergualin
    • R. J. Bergeron J. S. McManis 1987 Total synthesis of (±)-15- deoxyspergualin J. Org. Chem. 52 1700 1703
    • (1987) J. Org. Chem. , vol.52 , pp. 1700-1703
    • Bergeron, R.J.1    McManis, J.S.2
  • 45
    • 13444292883 scopus 로고    scopus 로고
    • Design, syntheses, and transfection biology of novel non- cholesterol-based guanidinylated cationic lipids
    • J. Sen A. Chaudhuri 2005 Design, syntheses, and transfection biology of novel non- cholesterol-based guanidinylated cationic lipids J. Med. Chem. 48 812 820
    • (2005) J. Med. Chem. , vol.48 , pp. 812-820
    • Sen, J.1    Chaudhuri, A.2
  • 46
    • 13844265668 scopus 로고    scopus 로고
    • Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery
    • H. S. Yoo J. E. Lee H. Chung I. C. Kwon S. Y. Jeong 2005 Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery J. Control. Release 103 235 243
    • (2005) J. Control. Release , vol.103 , pp. 235-243
    • Yoo, H.S.1    Lee, J.E.2    Chung, H.3    Kwon, I.C.4    Jeong, S.Y.5
  • 47
    • 0031447208 scopus 로고    scopus 로고
    • DNA condensation by multivalent cations
    • V. A. Bloomfield 1997 DNA condensation by multivalent cations Biopolymers 44 269 282
    • (1997) Biopolymers , vol.44 , pp. 269-282
    • Bloomfield, V.A.1
  • 48
    • 11844251258 scopus 로고    scopus 로고
    • Physicochemical characterization and gene transfection efficiency of lipid, emulsions with various co-emulsifiers
    • C. F. Hung T. L. Hwang C. C. Chang J. Y. Fang 2005 Physicochemical characterization and gene transfection efficiency of lipid, emulsions with various co-emulsifiers Int. J. Pharm. 289 197 208
    • (2005) Int. J. Pharm. , vol.289 , pp. 197-208
    • Hung, C.F.1    Hwang, T.L.2    Chang, C.C.3    Fang, J.Y.4
  • 49
    • 14044272234 scopus 로고    scopus 로고
    • Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters)
    • D. G. Anderson A. Akinc N. Hossain R. Langer 2005 Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters) Mol. Ther. 11 426 434
    • (2005) Mol. Ther. , vol.11 , pp. 426-434
    • Anderson, D.G.1    Akinc, A.2    Hossain, N.3    Langer, R.4
  • 50
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of cationic liposome-mediated gene delivery by polycations
    • X. Gao L. Huang 1996 Potentiation of cationic liposome-mediated gene delivery by polycations Biochemistry 35 1027 1036
    • (1996) Biochemistry , vol.35 , pp. 1027-1036
    • Gao, X.1    Huang, L.2
  • 52
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • J. Panyam V. Labhasetwar 2003 Biodegradable nanoparticles for drug and gene delivery to cells and tissue Adv. Drug Deliv. Rev. 55 329 347
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 54
    • 0034685930 scopus 로고    scopus 로고
    • Cheno-, urso- and deoxycholic acid spermine conjugates: Relative binding affinities for calf thymus DNA
    • I. S. Blagbrough D. Al-Hadithi A. J. Geall 2000 Cheno-, urso- and deoxycholic acid spermine conjugates: Relative binding affinities for calf thymus DNA Tetrahedron 56 3439 3447
    • (2000) Tetrahedron , vol.56 , pp. 3439-3447
    • Blagbrough, I.S.1    Al-Hadithi, D.2    Geall, A.J.3
  • 55
    • 5344263246 scopus 로고    scopus 로고
    • Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer
    • M. Ruponen P. Honkakoski M. Tammi A. Urtti 2004 Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer J. Gene Med. 6 405 414
    • (2004) J. Gene Med. , vol.6 , pp. 405-414
    • Ruponen, M.1    Honkakoski, P.2    Tammi, M.3    Urtti, A.4
  • 56
    • 0346494422 scopus 로고    scopus 로고
    • Compositional effects of cationic lipid/DNA delivery systems on transgene expression in cell culture
    • C. M. Wiethoff J. G. Koe G. S. Koe C. R. Middaugh 2004 Compositional effects of cationic lipid/DNA delivery systems on transgene expression in cell culture J. Pharm. Sci. 93 108 123
    • (2004) J. Pharm. Sci. , vol.93 , pp. 108-123
    • Wiethoff, C.M.1    Koe, J.G.2    Koe, G.S.3    Middaugh, C.R.4
  • 58
    • 34848817960 scopus 로고    scopus 로고
    • Cellular binding, motion, and internalization of synthetic gene delivery polymers
    • G. T. Hess W. H. Humphries N. C. Fay C. K. Payne 2007 Cellular binding, motion, and internalization of synthetic gene delivery polymers Biochim. Biophys. Acta 1773 1583 1588
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1583-1588
    • Hess, G.T.1    Humphries, W.H.2    Fay, N.C.3    Payne, C.K.4
  • 60
    • 0032881481 scopus 로고    scopus 로고
    • The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection
    • A. J. Geall M. A. W. Eaton T. Baker C. Catterall I. S. Blagbrough 1999 The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection FEBS Lett. 459 337 342
    • (1999) FEBS Lett. , vol.459 , pp. 337-342
    • Geall, A.J.1    Eaton, M.A.W.2    Baker, T.3    Catterall, C.4    Blagbrough, I.S.5
  • 61
    • 0037398046 scopus 로고    scopus 로고
    • Polyamines and novel polyamine conjugates interact with DNA in ways that can be exploited in non-viral gene therapy
    • I. S. Blagbrough A. J. Geall A. P. Neal 2003 Polyamines and novel polyamine conjugates interact with DNA in ways that can be exploited in non-viral gene therapy Biochem. Soc. Trans. 31 397 406
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 397-406
    • Blagbrough, I.S.1    Geall, A.J.2    Neal, A.P.3
  • 62
    • 33745605174 scopus 로고    scopus 로고
    • Lipopolyamine-mediated single nanoparticle formation of calf thymus DNA analyzed by fluorescence correlation spectroscopy
    • N. Adjimatera T. Kral M. Hof I. S. Blagbrough 2006 Lipopolyamine-mediated single nanoparticle formation of calf thymus DNA analyzed by fluorescence correlation spectroscopy Pharm. Res. 23 1564 1573
    • (2006) Pharm. Res. , vol.23 , pp. 1564-1573
    • Adjimatera, N.1    Kral, T.2    Hof, M.3    Blagbrough, I.S.4
  • 63
    • 0034801465 scopus 로고    scopus 로고
    • Rational approaches to the design of cationic gemini surfactants for gene delivery
    • C. McGregor C. Perrin M. Monck P. Camilleri A. J. Kirby 2001 Rational approaches to the design of cationic gemini surfactants for gene delivery J. Am. Chem. Soc. 123 6215 6220
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 6215-6220
    • McGregor, C.1    Perrin, C.2    Monck, M.3    Camilleri, P.4    Kirby, A.J.5
  • 65
    • 0032543524 scopus 로고    scopus 로고
    • Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery
    • J. K. Wang X. Guo Y. H. Xu L. Barron F. C. Szoka 1998 Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery J. Med. Chem. 41 2207 2215
    • (1998) J. Med. Chem. , vol.41 , pp. 2207-2215
    • Wang, J.K.1    Guo, X.2    Xu, Y.H.3    Barron, L.4    Szoka, F.C.5
  • 66
    • 0037011904 scopus 로고    scopus 로고
    • Synthesis of novel cationic lipids: Effect of structural modification on the efficiency of gene transfer
    • J. A. Heyes D. Niculescu-Duvaz R. G. Cooper C. J. Springer 2002 Synthesis of novel cationic lipids: Effect of structural modification on the efficiency of gene transfer J. Med. Chem. 45 99 114
    • (2002) J. Med. Chem. , vol.45 , pp. 99-114
    • Heyes, J.A.1    Niculescu-Duvaz, D.2    Cooper, R.G.3    Springer, C.J.4
  • 67
    • 29244457243 scopus 로고    scopus 로고
    • Structural variation of cationic lipids: Minimum requirement for improved oligonucleotide delivery into cells
    • L. H. Lindner R. Brock D. Arndt-Jovin H. Eibl 2006 Structural variation of cationic lipids: Minimum requirement for improved oligonucleotide delivery into cells J. Control. Release 110 444 456
    • (2006) J. Control. Release , vol.110 , pp. 444-456
    • Lindner, L.H.1    Brock, R.2    Arndt-Jovin, D.3    Eibl, H.4
  • 70
    • 0033036668 scopus 로고    scopus 로고
    • Stabilized plasmid-lipid particles: Factors influencing plasmid entrapment and transfection properties
    • K. W. C. Mok A. M. I. Lam P. R. Cullis 1999 Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties Biochim. Biophys. Acta Biomembr. 1419 137 150
    • (1999) Biochim. Biophys. Acta Biomembr. , vol.1419 , pp. 137-150
    • Mok, K.W.C.1    Lam, A.M.I.2    Cullis, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.