-
1
-
-
20844444135
-
Targeting Stat3 in cancer therapy
-
Jing N., and Tweardy D.J. Targeting Stat3 in cancer therapy. Anticancer Drugs 16 6 (2005) 601-607
-
(2005)
Anticancer Drugs
, vol.16
, Issue.6
, pp. 601-607
-
-
Jing, N.1
Tweardy, D.J.2
-
2
-
-
0034722896
-
STAT proteins: novel molecular targets for cancer drug discovery
-
Turkson J., and Jove R. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 19 (2000) 6613-6626
-
(2000)
Oncogene
, vol.19
, pp. 6613-6626
-
-
Turkson, J.1
Jove, R.2
-
3
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R., Mora L.B., and Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8 (2002) 945-954
-
(2002)
Clin Cancer Res
, vol.8
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
4
-
-
0029069540
-
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
-
Yu C.L., Meyer D.J., Campbell G.S., Larner A.C., Carter-Su C., Schwartz J., et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269 5220 (1995) 81-83
-
(1995)
Science
, vol.269
, Issue.5220
, pp. 81-83
-
-
Yu, C.L.1
Meyer, D.J.2
Campbell, G.S.3
Larner, A.C.4
Carter-Su, C.5
Schwartz, J.6
-
5
-
-
1042302005
-
The STATs of cancer-new molecular targets come of age
-
Yu H., and Jove R. The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 4 2 (2004) 97-105
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.2
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
6
-
-
0037444373
-
Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
-
Blaskovich M.A., Sun J., Cantor A., Turkson J., Jove R., and Sebti S.M. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 63 6 (2003) 1270-1279
-
(2003)
Cancer Res
, vol.63
, Issue.6
, pp. 1270-1279
-
-
Blaskovich, M.A.1
Sun, J.2
Cantor, A.3
Turkson, J.4
Jove, R.5
Sebti, S.M.6
-
7
-
-
0141955061
-
Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells
-
Bharti A.C., Donato N., and Aggarwal B.B. Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J Immunol 171 7 (2003) 3863-3871
-
(2003)
J Immunol
, vol.171
, Issue.7
, pp. 3863-3871
-
-
Bharti, A.C.1
Donato, N.2
Aggarwal, B.B.3
-
8
-
-
0035977055
-
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
-
Turkson J., Ryan D., Kim J.S., Zhang Y., Chen Z., Haura E., et al. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J Biol Chem 276 48 (2001) 45443-45455
-
(2001)
J Biol Chem
, vol.276
, Issue.48
, pp. 45443-45455
-
-
Turkson, J.1
Ryan, D.2
Kim, J.S.3
Zhang, Y.4
Chen, Z.5
Haura, E.6
-
9
-
-
35748976581
-
STAT3-decoy ODN inhibits cytokine autocrine of murine tumor cells
-
Liu X., Li J., and Zhang J. STAT3-decoy ODN inhibits cytokine autocrine of murine tumor cells. Cell Mol Immunol 4 4 (2007) 309-313
-
(2007)
Cell Mol Immunol
, vol.4
, Issue.4
, pp. 309-313
-
-
Liu, X.1
Li, J.2
Zhang, J.3
-
10
-
-
33847396951
-
Small molecule inhibitors of Stat3 signaling pathway
-
Deng J., Grande F., and Neamati N. Small molecule inhibitors of Stat3 signaling pathway. Curr Cancer Drug Targets 7 1 (2007) 91-107
-
(2007)
Curr Cancer Drug Targets
, vol.7
, Issue.1
, pp. 91-107
-
-
Deng, J.1
Grande, F.2
Neamati, N.3
-
11
-
-
64849111865
-
Targeting STAT3 in cancer: how successful are we?
-
Yue P., and Turkson J. Targeting STAT3 in cancer: how successful are we?. Expert Opin Investig Drugs 18 1 (2009) 45-56
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.1
, pp. 45-56
-
-
Yue, P.1
Turkson, J.2
-
12
-
-
30344454402
-
Short interfering RNA (siRNA): tool or therapeutic?
-
Cejka D., Losert D., and Wacheck V. Short interfering RNA (siRNA): tool or therapeutic?. Clin Sci (Lond) 110 1 (2006) 47-58
-
(2006)
Clin Sci (Lond)
, vol.110
, Issue.1
, pp. 47-58
-
-
Cejka, D.1
Losert, D.2
Wacheck, V.3
-
13
-
-
15244350338
-
Inhibition of STAT3 expression by siRNA suppresses growth and induces apoptosis in laryngeal cancer cells
-
Gao L.F., Xu D.Q., Wen L.J., Zhang X.Y., Shao Y.T., and Zhao X.J. Inhibition of STAT3 expression by siRNA suppresses growth and induces apoptosis in laryngeal cancer cells. Acta Pharmacol Sin 26 3 (2005) 377-383
-
(2005)
Acta Pharmacol Sin
, vol.26
, Issue.3
, pp. 377-383
-
-
Gao, L.F.1
Xu, D.Q.2
Wen, L.J.3
Zhang, X.Y.4
Shao, Y.T.5
Zhao, X.J.6
-
14
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
Konnikova L., Kotecki M., Kruger M.M., and Cochran B.H. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 3 (2003) 23
-
(2003)
BMC Cancer
, vol.3
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
15
-
-
0347756922
-
Toxicogenomics of non-viral vectors for gene therapy: a microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells
-
Omidi Y., Hollins A.J., Benboubetra M., Drayton R., Benter I.F., and Akhtar S. Toxicogenomics of non-viral vectors for gene therapy: a microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells. J Drug Target 11 6 (2003) 311-323
-
(2003)
J Drug Target
, vol.11
, Issue.6
, pp. 311-323
-
-
Omidi, Y.1
Hollins, A.J.2
Benboubetra, M.3
Drayton, R.4
Benter, I.F.5
Akhtar, S.6
-
16
-
-
34248650151
-
Non-viral siRNA delivery to the lung
-
Thomas M., Lu J.J., Chen J., and Klibanov A.M. Non-viral siRNA delivery to the lung. Adv Drug Deliv Rev 59 2-3 (2007) 124-133
-
(2007)
Adv Drug Deliv Rev
, vol.59
, Issue.2-3
, pp. 124-133
-
-
Thomas, M.1
Lu, J.J.2
Chen, J.3
Klibanov, A.M.4
-
17
-
-
26944499005
-
The therapeutic potential of RNA interference
-
Uprichard S.L. The therapeutic potential of RNA interference. FEBS Lett 579 26 (2005) 5996-6007
-
(2005)
FEBS Lett
, vol.579
, Issue.26
, pp. 5996-6007
-
-
Uprichard, S.L.1
-
18
-
-
0037147179
-
Breakthrough of the year
-
Kennedy D. Breakthrough of the year. Science 298 5602 (2002) 2283
-
(2002)
Science
, vol.298
, Issue.5602
, pp. 2283
-
-
Kennedy, D.1
-
19
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke M.A. Progress towards in vivo use of siRNAs. Mol Ther 13 4 (2006) 644-670
-
(2006)
Mol Ther
, vol.13
, Issue.4
, pp. 644-670
-
-
Behlke, M.A.1
-
20
-
-
33748747613
-
RNA-interference effectors and their delivery
-
Putnam D., and Doody A. RNA-interference effectors and their delivery. Crit Rev Ther Drug Carrier Syst 23 2 (2006) 137-164
-
(2006)
Crit Rev Ther Drug Carrier Syst
, vol.23
, Issue.2
, pp. 137-164
-
-
Putnam, D.1
Doody, A.2
-
21
-
-
33645891183
-
Polyethylenimine (PEI)
-
Demeneix B., and Behr J.P. Polyethylenimine (PEI). Adv Genet 53 (2005) 217-230
-
(2005)
Adv Genet
, vol.53
, pp. 217-230
-
-
Demeneix, B.1
Behr, J.P.2
-
22
-
-
33646190173
-
Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs
-
Aigner A. Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs. J Biotechnol 124 1 (2006) 12-25
-
(2006)
J Biotechnol
, vol.124
, Issue.1
, pp. 12-25
-
-
Aigner, A.1
-
23
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
Urban-Klein B., Werth S., Abuharbeid S., Czubayko F., and Aigner A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther 12 5 (2005) 461-466
-
(2005)
Gene Ther
, vol.12
, Issue.5
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
24
-
-
20444377785
-
Polyethylenimine-based non-viral gene delivery systems
-
Lungwitz U., Breunig M., Blunk T., and Gopferich A. Polyethylenimine-based non-viral gene delivery systems. Eur J Pharm Biopharm 60 2 (2005) 247-266
-
(2005)
Eur J Pharm Biopharm
, vol.60
, Issue.2
, pp. 247-266
-
-
Lungwitz, U.1
Breunig, M.2
Blunk, T.3
Gopferich, A.4
-
25
-
-
0032892476
-
Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
-
Godbey W.T., Wu K.K., and Mikos A.G. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J Biomed Mater Res 45 3 (1999) 268-275
-
(1999)
J Biomed Mater Res
, vol.45
, Issue.3
, pp. 268-275
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
26
-
-
62649108009
-
Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine
-
Alshamsan A., Haddadi A., Incani V., Samuel J., Lavasanifar A., and Uludag H. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. Mol Pharm 6 1 (2009) 121-133
-
(2009)
Mol Pharm
, vol.6
, Issue.1
, pp. 121-133
-
-
Alshamsan, A.1
Haddadi, A.2
Incani, V.3
Samuel, J.4
Lavasanifar, A.5
Uludag, H.6
-
27
-
-
46949083070
-
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis
-
Kataoka K., Kim D.J., Carbajal S., Clifford J.L., and DiGiovanni J. Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis. Carcinogenesis 29 6 (2008) 1108-1114
-
(2008)
Carcinogenesis
, vol.29
, Issue.6
, pp. 1108-1114
-
-
Kataoka, K.1
Kim, D.J.2
Carbajal, S.3
Clifford, J.L.4
DiGiovanni, J.5
-
28
-
-
34247620340
-
Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells
-
Incani V., Tunis E., Clements B.A., Olson C., Kucharski C., Lavasanifar A., et al. Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells. J Biomed Mater Res A 81 2 (2007) 493-504
-
(2007)
J Biomed Mater Res A
, vol.81
, Issue.2
, pp. 493-504
-
-
Incani, V.1
Tunis, E.2
Clements, B.A.3
Olson, C.4
Kucharski, C.5
Lavasanifar, A.6
-
29
-
-
0013689209
-
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro
-
Grandis J.R., Drenning S.D., Chakraborty A., Zhou M.Y., Zeng Q., Pitt A.S., et al. Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro. J Clin Invest 102 7 (1998) 1385-1392
-
(1998)
J Clin Invest
, vol.102
, Issue.7
, pp. 1385-1392
-
-
Grandis, J.R.1
Drenning, S.D.2
Chakraborty, A.3
Zhou, M.Y.4
Zeng, Q.5
Pitt, A.S.6
-
30
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora L.B., Buettner R., Seigne J., Diaz J., Ahmad N., Garcia R., et al. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 62 22 (2002) 6659-6666
-
(2002)
Cancer Res
, vol.62
, Issue.22
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
Diaz, J.4
Ahmad, N.5
Garcia, R.6
-
31
-
-
47349089471
-
STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNalpha therapy
-
Wang W., Edington H.D., Rao U.N., Jukic D.M., Wang H., Shipe-Spotloe J.M., et al. STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNalpha therapy. J Invest Dermatol 128 8 (2008) 1997-2002
-
(2008)
J Invest Dermatol
, vol.128
, Issue.8
, pp. 1997-2002
-
-
Wang, W.1
Edington, H.D.2
Rao, U.N.3
Jukic, D.M.4
Wang, H.5
Shipe-Spotloe, J.M.6
-
32
-
-
20944441928
-
Validating Stat3 in cancer therapy
-
Darnell J.E. Validating Stat3 in cancer therapy. Nat Med 11 6 (2005) 595-596
-
(2005)
Nat Med
, vol.11
, Issue.6
, pp. 595-596
-
-
Darnell, J.E.1
-
33
-
-
38849199799
-
STAT3 as a target for inducing apoptosis in solid and hematological tumors
-
Al Zaid Siddiquee K., and Turkson J. STAT3 as a target for inducing apoptosis in solid and hematological tumors. Cell Res 18 2 (2008) 254-267
-
(2008)
Cell Res
, vol.18
, Issue.2
, pp. 254-267
-
-
Al Zaid Siddiquee, K.1
Turkson, J.2
-
34
-
-
40149094813
-
Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells
-
Xiong H., Zhang Z.G., Tian X.Q., Sun D.F., Liang Q.C., Zhang Y.J., et al. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia 10 3 (2008) 287-297
-
(2008)
Neoplasia
, vol.10
, Issue.3
, pp. 287-297
-
-
Xiong, H.1
Zhang, Z.G.2
Tian, X.Q.3
Sun, D.F.4
Liang, Q.C.5
Zhang, Y.J.6
-
35
-
-
65249189344
-
Phase II trial of tipifarnib plus neoadjuvant doxorubicin-cyclophosphamide in patients with clinical stage IIB-IIIC breast cancer
-
Sparano J.A., Moulder S., Kazi A., Coppola D., Negassa A., Vahdat L., et al. Phase II trial of tipifarnib plus neoadjuvant doxorubicin-cyclophosphamide in patients with clinical stage IIB-IIIC breast cancer. Clin Cancer Res 15 8 (2009) 2942-2948
-
(2009)
Clin Cancer Res
, vol.15
, Issue.8
, pp. 2942-2948
-
-
Sparano, J.A.1
Moulder, S.2
Kazi, A.3
Coppola, D.4
Negassa, A.5
Vahdat, L.6
-
36
-
-
33646928625
-
STAT3-independent inhibition of lysophosphatidic acid-mediated upregulation of connective tissue growth factor (CTGF) by cucurbitacin I
-
Graness A., Poli V., and Goppelt-Struebe M. STAT3-independent inhibition of lysophosphatidic acid-mediated upregulation of connective tissue growth factor (CTGF) by cucurbitacin I. Biochem Pharmacol 72 1 (2006) 32-41
-
(2006)
Biochem Pharmacol
, vol.72
, Issue.1
, pp. 32-41
-
-
Graness, A.1
Poli, V.2
Goppelt-Struebe, M.3
-
37
-
-
43949131788
-
Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells
-
Mackenzie G.G., Queisser N., Wolfson M.L., Fraga C.G., Adamo A.M., and Oteiza P.I. Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells. Int J Cancer 123 1 (2008) 56-65
-
(2008)
Int J Cancer
, vol.123
, Issue.1
, pp. 56-65
-
-
Mackenzie, G.G.1
Queisser, N.2
Wolfson, M.L.3
Fraga, C.G.4
Adamo, A.M.5
Oteiza, P.I.6
-
38
-
-
51649118928
-
Phase II trial of curcumin in patients with advanced pancreatic cancer
-
Dhillon N., Aggarwal B.B., Newman R.A., Wolff R.A., Kunnumakkara A.B., Abbruzzese J.L., et al. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res 14 14 (2008) 4491-4499
-
(2008)
Clin Cancer Res
, vol.14
, Issue.14
, pp. 4491-4499
-
-
Dhillon, N.1
Aggarwal, B.B.2
Newman, R.A.3
Wolff, R.A.4
Kunnumakkara, A.B.5
Abbruzzese, J.L.6
-
39
-
-
33646685202
-
Delivery strategies for siRNA-mediated gene silencing
-
Gilmore I.R., Fox S.P., Hollins A.J., and Akhtar S. Delivery strategies for siRNA-mediated gene silencing. Curr Drug Deliv 3 2 (2006) 145-155
-
(2006)
Curr Drug Deliv
, vol.3
, Issue.2
, pp. 145-155
-
-
Gilmore, I.R.1
Fox, S.P.2
Hollins, A.J.3
Akhtar, S.4
-
40
-
-
33745885674
-
STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines
-
Zhou W., Grandis J.R., and Wells A. STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines. Br J Cancer 95 2 (2006) 164-171
-
(2006)
Br J Cancer
, vol.95
, Issue.2
, pp. 164-171
-
-
Zhou, W.1
Grandis, J.R.2
Wells, A.3
-
41
-
-
0035870249
-
Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
-
Niu G., Shain K.H., Huang M., Ravi R., Bedi A., Dalton W.S., et al. Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res 61 8 (2001) 3276-3280
-
(2001)
Cancer Res
, vol.61
, Issue.8
, pp. 3276-3280
-
-
Niu, G.1
Shain, K.H.2
Huang, M.3
Ravi, R.4
Bedi, A.5
Dalton, W.S.6
-
42
-
-
33845216721
-
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
-
Kim S.H., Jeong J.H., Lee S.H., Kim S.W., and Park T.G. PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J Control Release 116 2 (2006) 123-129
-
(2006)
J Control Release
, vol.116
, Issue.2
, pp. 123-129
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
43
-
-
46549085779
-
Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer
-
Kim S.H., Jeong J.H., Lee S.H., Kim S.W., and Park T.G. Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer. J Control Release 129 2 (2008) 107-116
-
(2008)
J Control Release
, vol.129
, Issue.2
, pp. 107-116
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
44
-
-
42649145837
-
Interactions of host IL-6 and IFN-gamma and cancer-derived TGF-beta1 on MHC molecule expression during tumor spontaneous regression
-
Hsiao Y.W., Liao K.W., Chung T.F., Liu C.H., Hsu C.D., and Chu R.M. Interactions of host IL-6 and IFN-gamma and cancer-derived TGF-beta1 on MHC molecule expression during tumor spontaneous regression. Cancer Immunol Immunother 57 7 (2008) 1091-1104
-
(2008)
Cancer Immunol Immunother
, vol.57
, Issue.7
, pp. 1091-1104
-
-
Hsiao, Y.W.1
Liao, K.W.2
Chung, T.F.3
Liu, C.H.4
Hsu, C.D.5
Chu, R.M.6
-
45
-
-
0033556164
-
The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro
-
Rakemann T., Niehof M., Kubicka S., Fischer M., Manns M.P., Rose-John S., et al. The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro. J Biol Chem 274 3 (1999) 1257-1266
-
(1999)
J Biol Chem
, vol.274
, Issue.3
, pp. 1257-1266
-
-
Rakemann, T.1
Niehof, M.2
Kubicka, S.3
Fischer, M.4
Manns, M.P.5
Rose-John, S.6
-
46
-
-
24344499530
-
Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation
-
Haan S., Keller J.F., Behrmann I., Heinrich P.C., and Haan C. Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation. Cell Signal 17 12 (2005) 1542-1550
-
(2005)
Cell Signal
, vol.17
, Issue.12
, pp. 1542-1550
-
-
Haan, S.1
Keller, J.F.2
Behrmann, I.3
Heinrich, P.C.4
Haan, C.5
-
47
-
-
0037062503
-
Mutational switch of an IL-6 response to an interferon-gamma-like response
-
Costa-Pereira A.P., Tininini S., Strobl B., Alonzi T., Schlaak J.F., Is'harc H., et al. Mutational switch of an IL-6 response to an interferon-gamma-like response. Proc Natl Acad Sci U S A 99 12 (2002) 8043-8047
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.12
, pp. 8043-8047
-
-
Costa-Pereira, A.P.1
Tininini, S.2
Strobl, B.3
Alonzi, T.4
Schlaak, J.F.5
Is'harc, H.6
-
48
-
-
0036161827
-
Inhibition of B16 melanoma experimental metastasis by interferon-gamma through direct inhibition of cell proliferation and activation of antitumour host mechanisms
-
Kakuta S., Tagawa Y., Shibata S., Nanno M., and Iwakura Y. Inhibition of B16 melanoma experimental metastasis by interferon-gamma through direct inhibition of cell proliferation and activation of antitumour host mechanisms. Immunology 105 1 (2002) 92-100
-
(2002)
Immunology
, vol.105
, Issue.1
, pp. 92-100
-
-
Kakuta, S.1
Tagawa, Y.2
Shibata, S.3
Nanno, M.4
Iwakura, Y.5
-
49
-
-
0033554041
-
Cell-specific differences in the regulation of IL-6 expression by PMA
-
Costanzo C., Piacentini G., Vicentini L., Armenante F., Mazzi P., Savio C., et al. Cell-specific differences in the regulation of IL-6 expression by PMA. Biochem Biophys Res Commun 260 3 (1999) 577-581
-
(1999)
Biochem Biophys Res Commun
, vol.260
, Issue.3
, pp. 577-581
-
-
Costanzo, C.1
Piacentini, G.2
Vicentini, L.3
Armenante, F.4
Mazzi, P.5
Savio, C.6
-
50
-
-
0025343895
-
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
-
Libermann T.A., and Baltimore D. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol Cell Biol 10 5 (1990) 2327-2334
-
(1990)
Mol Cell Biol
, vol.10
, Issue.5
, pp. 2327-2334
-
-
Libermann, T.A.1
Baltimore, D.2
-
51
-
-
65549111372
-
Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy
-
Kortylewski M., Kujawski M., Herrmann A., Yang C., Wang L., Liu Y., et al. Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy. Cancer Res 69 6 (2009) 2497-2505
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2497-2505
-
-
Kortylewski, M.1
Kujawski, M.2
Herrmann, A.3
Yang, C.4
Wang, L.5
Liu, Y.6
-
52
-
-
34249681852
-
An RNA-binding protein alphaCP-1 is involved in the STAT3-mediated suppression of NF-kappaB transcriptional activity
-
Nishinakamura H., Minoda Y., Saeki K., Koga K., Takaesu G., Onodera M., et al. An RNA-binding protein alphaCP-1 is involved in the STAT3-mediated suppression of NF-kappaB transcriptional activity. Int Immunol 19 5 (2007) 609-619
-
(2007)
Int Immunol
, vol.19
, Issue.5
, pp. 609-619
-
-
Nishinakamura, H.1
Minoda, Y.2
Saeki, K.3
Koga, K.4
Takaesu, G.5
Onodera, M.6
-
53
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang T., Niu G., Kortylewski M., Burdelya L., Shain K., Zhang S., et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 10 1 (2004) 48-54
-
(2004)
Nat Med
, vol.10
, Issue.1
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
Burdelya, L.4
Shain, K.5
Zhang, S.6
-
54
-
-
0036797750
-
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB
-
Yu Z., Zhang W., and Kone B.C. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem J 367 Pt 1 (2002) 97-105
-
(2002)
Biochem J
, vol.367
, Issue.PART 1
, pp. 97-105
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
55
-
-
41849116690
-
Roles of unphosphorylated STATs in signaling
-
Yang J., and Stark G.R. Roles of unphosphorylated STATs in signaling. Cell Res 18 4 (2008) 443-451
-
(2008)
Cell Res
, vol.18
, Issue.4
, pp. 443-451
-
-
Yang, J.1
Stark, G.R.2
-
56
-
-
39549102220
-
STAT3: a critical transcription activator in angiogenesis
-
Chen Z., and Han Z.C. STAT3: a critical transcription activator in angiogenesis. Med Res Rev 28 2 (2008) 185-200
-
(2008)
Med Res Rev
, vol.28
, Issue.2
, pp. 185-200
-
-
Chen, Z.1
Han, Z.C.2
-
57
-
-
35848962527
-
Augmented antitumor effects of combination therapy with VEGF antibody and cisplatin on murine B16F10 melanoma cells
-
Ghosh S., and Maity P. Augmented antitumor effects of combination therapy with VEGF antibody and cisplatin on murine B16F10 melanoma cells. Int Immunopharmacol 7 13 (2007) 1598-1608
-
(2007)
Int Immunopharmacol
, vol.7
, Issue.13
, pp. 1598-1608
-
-
Ghosh, S.1
Maity, P.2
-
58
-
-
0032718891
-
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
-
Niu G., Heller R., Catlett-Falcone R., Coppola D., Jaroszeski M., Dalton W., et al. Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res 59 20 (1999) 5059-5063
-
(1999)
Cancer Res
, vol.59
, Issue.20
, pp. 5059-5063
-
-
Niu, G.1
Heller, R.2
Catlett-Falcone, R.3
Coppola, D.4
Jaroszeski, M.5
Dalton, W.6
|