-
1
-
-
0036806311
-
Evolution of protein kinase signaling from yeast to man
-
Manning, G., Plowman, G. D., Hunter, T. and Sudarsanam, S. (2002) Evolution of protein kinase signaling from yeast to man. Trends Biochem. Sci. 27, 514-520
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 514-520
-
-
Manning, G.1
Plowman, G.D.2
Hunter, T.3
Sudarsanam, S.4
-
2
-
-
0036830564
-
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival
-
DOI 10.1053/jhep.2002.36160
-
Coutant, A., Rescan, C., Gilot, D., Loyer, P., Guguen-Guillouzo, C. and Baffet, G. (2002) PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival. Hepatology 36, 1079-1088 (Pubitemid 35253423)
-
(2002)
Hepatology
, vol.36
, Issue.5 II
, pp. 1079-1088
-
-
Coutant, A.1
Rescan, C.2
Gilot, D.3
Loyer, P.4
Guguen-Guillouzo, C.5
Baffet, G.6
-
3
-
-
33744990592
-
Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation
-
DOI 10.1038/nature04694, PII NATURE04694
-
Foukas, L. C., Claret, M., Pearce, W., Okkenhaug, K., Meek, S., Peskett, E., Sancho, S., Smith, A. J., Withers, D. J. and Vanhaesebroeck, B. (2006) Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature 441, 366-370 (Pubitemid 44050203)
-
(2006)
Nature
, vol.441
, Issue.7091
, pp. 366-370
-
-
Foukas, L.C.1
Claret, M.2
Pearce, W.3
Okkenhaug, K.4
Meek, S.5
Peskett, E.6
Sancho, S.7
Smith, A.J.H.8
Withers, D.J.9
Vanhaesebroeck, B.10
-
4
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke, T. F., Kaplan, D. R. and Cantley, L. C. (1997) PI3K: downstream AKTion blocks apoptosis. Cell 88, 435-437
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
5
-
-
0026672998
-
MAP kinases: Charting the regulatory pathways
-
Pelech, S. L. and Sanghera, J. S. (1992) MAP kinases: charting the regulatory pathways. Science 257, 1355-1356
-
(1992)
Science
, vol.257
, pp. 1355-1356
-
-
Pelech, S.L.1
Sanghera, J.S.2
-
6
-
-
0034635264
-
Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki, T., Irie-Sasaki, J., Jones, R. G., Oliveira-dos-Santos, A. J., Stanford, W. L., Bolon, B., Wakeham, A., Itie, A., Bouchard, D., Kozieradzki, I. et al. (2000) Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration. Science 287, 1040-1046
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-Dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
Wakeham, A.7
Itie, A.8
Bouchard, D.9
Kozieradzki, I.10
-
7
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesebroeck, B. and Alessi, D. R. (2000) The PI3K-PDK1 connection: more than just a road to PKB. Biochem J. 346, 561-576
-
(2000)
Biochem J.
, vol.346
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
8
-
-
0034625170
-
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
-
Xia, Y., Makris, C., Su, B., Li, E., Yang, J., Nemerow, G. R. and Karin, M. (2000) MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc. Natl. Acad. Sci. U.S.A. 97, 5243-5248
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5243-5248
-
-
Xia, Y.1
Makris, C.2
Su, B.3
Li, E.4
Yang, J.5
Nemerow, G.R.6
Karin, M.7
-
9
-
-
0033968126
-
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
-
Cusi, K., Maezono, K., Osman, A., Pendergrass, M., Patti, M. E., Pratipanawatr, T., DeFronzo, R. A., Kahn, C. R. and Mandarino, L. J. (2000) Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J. Clin. Invest. 105, 311-320
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 311-320
-
-
Cusi, K.1
Maezono, K.2
Osman, A.3
Pendergrass, M.4
Patti, M.E.5
Pratipanawatr, T.6
DeFronzo, R.A.7
Kahn, C.R.8
Mandarino, L.J.9
-
10
-
-
33745815985
-
AMP-activated protein kinase signaling in metabolic regulation
-
Long, Y. C. and Zierath, J. R. (2006) AMP-activated protein kinase signaling in metabolic regulation. J. Clin. Invest. 116, 1776-1783
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1776-1783
-
-
Long, Y.C.1
Zierath, J.R.2
-
11
-
-
1642382889
-
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: Implications for neurodegenerative diseases
-
Mandel, S., Weinreb, O., Amit, T. and Youdim, M. B. (2004) Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases. J. Neurochem. 88, 1555-1569
-
(2004)
J. Neurochem.
, vol.88
, pp. 1555-1569
-
-
Mandel, S.1
Weinreb, O.2
Amit, T.3
Youdim, M.B.4
-
12
-
-
33646190885
-
The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases
-
Sekine, Y., Takeda, K. and Ichijo, H. (2006) The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases. Curr. Mol. Med. 6, 87-97
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 87-97
-
-
Sekine, Y.1
Takeda, K.2
Ichijo, H.3
-
13
-
-
66749134594
-
Targeting innate immunity protein kinase signalling in inflammation
-
Gaestel, M., Kotlyarov, A. and Kracht, M. (2009) Targeting innate immunity protein kinase signalling in inflammation. Nat. Rev. Drug Discovery 8, 480-499
-
(2009)
Nat. Rev. Drug Discovery
, vol.8
, pp. 480-499
-
-
Gaestel, M.1
Kotlyarov, A.2
Kracht, M.3
-
14
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
DOI 10.1038/sj.onc.1204349
-
Garcia, R., Bowman, T. L., Niu, G., Yu, H., Minton, S., Muro-Cacho, C. A., Cox, C. E., Falcone, R., Fairclough, R., Parsons, S. et al. (2001) Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20, 2499-2513 (Pubitemid 32531347)
-
(2001)
Oncogene
, vol.20
, Issue.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
Yu, H.4
Minton, S.5
Muro-Cacho, C.A.6
Cox, C.E.7
Falcone, R.8
Fairclough, R.9
Parsons, S.10
Laudano, A.11
Gazit, A.12
Levitzki, A.13
Kraker, A.14
Jove, R.15
-
15
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy, B. T., Smith, D. L., Ram, P. T., Lu, Y. and Mills, G. B. (2005) Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat. Rev. Drug Discovery 4, 988-1004
-
(2005)
Nat. Rev. Drug Discovery
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
16
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
Luo, J., Manning, B. D. and Cantley, L. C. (2003) Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4, 257-262
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
17
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
DOI 10.1038/sj.onc.1210422, PII 1210422
-
Roberts, P. J. and Der, C. J. (2007) Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26, 3291-3310 (Pubitemid 46763022)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
18
-
-
0036607064
-
Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
-
Stork, P. J. and Schmitt, J. M. (2002) Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol. 12, 258-266
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 258-266
-
-
Stork, P.J.1
Schmitt, J.M.2
-
19
-
-
0037163050
-
Regulation of Raf-Akt Cross-talk
-
Moelling, K., Schad, K., Bosse, M., Zimmermann, S. and Schweneker, M. (2002) Regulation of Raf-Akt Cross-talk. J. Biol. Chem. 277, 31099-31106
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
20
-
-
0033607784
-
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt
-
Rommel, C., Clarke, B. A., Zimmermann, S., Nunez, L., Rossman, R., Reid, K., Moelling, K., Yancopoulos, G. D. and Glass, D. J. (1999) Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286, 1738-1741 (Pubitemid 129515881)
-
(1999)
Science
, vol.286
, Issue.5445
, pp. 1738-1741
-
-
Rommel, C.1
Clarke, B.A.2
Zimmermann, S.3
Nunez, L.4
Rossman, R.5
Reid, K.6
Moelling, K.7
Yancopoulos, G.D.8
Glass, D.J.9
-
21
-
-
0036295365
-
Molecular crosstalk between p70S6k and MAPK cell signaling pathways
-
Lehman, J. A. and Gomez-Cambronero, J. (2002) Molecular crosstalk between p70S6k and MAPK cell signaling pathways. Biochem. Biophys. Res. Commun. 293, 463-469
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 463-469
-
-
Lehman, J.A.1
Gomez-Cambronero, J.2
-
22
-
-
65549142508
-
Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines
-
Ulivi, P., Arienti, C., Amadori, D., Fabbri, F., Carloni, S., Tesei, A., Vannini, I., Silvestrini, R. and Zoli, W. (2009) Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines. J. Cell. Physiol. 220, 214-221
-
(2009)
J. Cell. Physiol.
, vol.220
, pp. 214-221
-
-
Ulivi, P.1
Arienti, C.2
Amadori, D.3
Fabbri, F.4
Carloni, S.5
Tesei, A.6
Vannini, I.7
Silvestrini, R.8
Zoli, W.9
-
23
-
-
0034625005
-
Cell signaling pathways as control modules: Complexity for simplicity?
-
Lauffenburger, D. A. (2000) Cell signaling pathways as control modules: complexity for simplicity? Proc. Natl. Acad. Sci. U.S.A. 97, 5031-5033
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5031-5033
-
-
Lauffenburger, D.A.1
-
24
-
-
33644524741
-
Cell-signalling dynamics in time and space
-
Kholodenko, B. N. (2006) Cell-signalling dynamics in time and space. Nat. Rev. Mol. Cell Biol. 7, 165-176
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 165-176
-
-
Kholodenko, B.N.1
-
25
-
-
0029790351
-
Ultrasensitivity in the mitogen-activated protein kinase cascade
-
Huang, C. Y. and Ferrell, Jr, J. E. (1996) Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. U.S.A. 93, 10078-10083
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 10078-10083
-
-
Huang, C.Y.1
Ferrell Jr., J.E.2
-
26
-
-
4544346660
-
Robustness of cellular functions
-
DOI 10.1016/j.cell.2004.09.008, PII S0092867404008402
-
Stelling, J., Sauer, U., Szallasi, Z., Doyle, 3rd, F. J. and Doyle, J. (2004) Robustness of cellular functions. Cell 118, 675-685 (Pubitemid 39221728)
-
(2004)
Cell
, vol.118
, Issue.6
, pp. 675-685
-
-
Stelling, J.1
Sauer, U.2
Szallasi, Z.3
Doyle III, F.J.4
Doyle, J.5
-
27
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla, U. S. and Iyengar, R. (1999) Emergent properties of networks of biological signaling pathways. Science 283, 381-387
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
29
-
-
28844441230
-
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
-
Janes, K. A., Albeck, J. G., Gaudet, S., Sorger, P. K., Lauffenburger, D. A. and Yaffe, M. B. (2005) A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 310, 1646-1653
-
(2005)
Science
, vol.310
, pp. 1646-1653
-
-
Janes, K.A.1
Albeck, J.G.2
Gaudet, S.3
Sorger, P.K.4
Lauffenburger, D.A.5
Yaffe, M.B.6
-
30
-
-
70349518562
-
Positive selection of tyrosine loss in metazoan evolution
-
Tan, C. S., Pasculescu, A., Lim, W. A., Pawson, T., Bader, G. D. and Linding, R. (2009) Positive selection of tyrosine loss in metazoan evolution. Science 325, 1686-1688
-
(2009)
Science
, vol.325
, pp. 1686-1688
-
-
Tan, C.S.1
Pasculescu, A.2
Lim, W.A.3
Pawson, T.4
Bader, G.D.5
Linding, R.6
-
31
-
-
59849125136
-
Dynamic modularity in protein interaction networks predicts breast cancer outcome
-
Taylor, I. W., Linding, R., Warde-Farley, D., Liu, Y., Pesquita, C., Faria, D., Bull, S., Pawson, T., Morris, Q. and Wrana, J. L. (2009) Dynamic modularity in protein interaction networks predicts breast cancer outcome. Nat. Biotechnol. 27, 199-204
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 199-204
-
-
Taylor, I.W.1
Linding, R.2
Warde-Farley, D.3
Liu, Y.4
Pesquita, C.5
Faria, D.6
Bull, S.7
Pawson, T.8
Morris, Q.9
Wrana, J.L.10
-
32
-
-
30044441052
-
KESTREL: A powerful method for identifying the physiological substrates of protein kinases
-
DOI 10.1042/BJ20051545
-
Cohen, P. and Knebel, A. (2006) KESTREL: a powerful method for identifying the physiological substrates of protein kinases. Biochem. J. 393, 1-6 (Pubitemid 43049297)
-
(2006)
Biochemical Journal
, vol.393
, Issue.1
, pp. 1-6
-
-
Cohen, P.1
Knebelt, A.2
-
33
-
-
77953077420
-
A global protein kinase and phosphatase interaction network in yeast
-
Breitkreutz, A., Choi, H., Sharom, J. R., Boucher, L., Neduva, V., Larsen, B., Lin, Z. Y., Breitkreutz, B. J., Stark, C., Liu, G. et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328, 1043-1046
-
(2010)
Science
, vol.328
, pp. 1043-1046
-
-
Breitkreutz, A.1
Choi, H.2
Sharom, J.R.3
Boucher, L.4
Neduva, V.5
Larsen, B.6
Lin, Z.Y.7
Breitkreutz, B.J.8
Stark, C.9
Liu, G.10
-
34
-
-
73349139547
-
Cell fate decisions are specified by the dynamic ERK interactome
-
von Kriegsheim, A., Baiocchi, D., Birtwistle, M., Sumpton, D., Bienvenut, W., Morrice, N., Yamada, K., Lamond, A., Kalna, G., Orton, R. et al. (2009) Cell fate decisions are specified by the dynamic ERK interactome. Nat. Cell Biol. 11, 1458-1464
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1458-1464
-
-
Von Kriegsheim, A.1
Baiocchi, D.2
Birtwistle, M.3
Sumpton, D.4
Bienvenut, W.5
Morrice, N.6
Yamada, K.7
Lamond, A.8
Kalna, G.9
Orton, R.10
-
35
-
-
66149125644
-
Challenges and opportunities in defining the essential cancer kinome
-
Manning, B. D. (2009) Challenges and opportunities in defining the essential cancer kinome. Sci. Signaling 2, pe15
-
(2009)
Sci. Signaling
, vol.2
-
-
Manning, B.D.1
-
36
-
-
56949094800
-
Targeted therapies in breast cancer: Where are we now?
-
Di Cosimo, S. and Baselga, J. (2008) Targeted therapies in breast cancer: where are we now? Eur. J. Cancer 44, 2781-2790
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 2781-2790
-
-
Di Cosimo, S.1
Baselga, J.2
-
37
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel, C. L., Cobleigh, M. A., Tripathy, D., Gutheil, J. C., Harris, L. N., Fehrenbacher, L., Slamon, D. J., Murphy, M., Novotny, W. F., Burchmore, M. et al. (2002) Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 20, 719-726
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
-
38
-
-
34848929062
-
Flying under the radar: The new wave of BCR-ABL inhibitors
-
Quintas-Cardama, A., Kantarjian, H. and Cortes, J. (2007) Flying under the radar: the new wave of BCR-ABL inhibitors. Nat. Rev. Drug Discovery 6, 834-848
-
(2007)
Nat. Rev. Drug Discovery
, vol.6
, pp. 834-848
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Cortes, J.3
-
39
-
-
55949117661
-
Kinase requirements in human cells. I. Comparing kinase requirements across various cell types
-
Grueneberg, D. A., Degot, S., Pearlberg, J., Li, W., Davies, J. E., Baldwin, A., Endege, W., Doench, J., Sawyer, J., Hu, Y. et al. (2008) Kinase requirements in human cells. I. Comparing kinase requirements across various cell types. Proc. Natl. Acad. Sci. U.S.A. 105, 16472-16477
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 16472-16477
-
-
Grueneberg, D.A.1
Degot, S.2
Pearlberg, J.3
Li, W.4
Davies, J.E.5
Baldwin, A.6
Endege, W.7
Doench, J.8
Sawyer, J.9
Hu, Y.10
-
40
-
-
55949096610
-
Kinase requirements in human cells. IV. Differential kinase requirements in cervical and renal human tumor cell lines
-
Grueneberg, D. A., Li, W., Davies, J. E., Sawyer, J., Pearlberg, J. and Harlow, E. (2008) Kinase requirements in human cells. IV. Differential kinase requirements in cervical and renal human tumor cell lines. Proc. Natl. Acad. Sci. U.S.A. 105, 16490-16495
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 16490-16495
-
-
Grueneberg, D.A.1
Li, W.2
Davies, J.E.3
Sawyer, J.4
Pearlberg, J.5
Harlow, E.6
-
41
-
-
38849098442
-
Cancer proliferation gene discovery through functional genomics
-
DOI 10.1126/science.1149200
-
Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q., Li, M. Z., Zhao, Z., Smogorzewska, A., Sowa, M. E., Ang, X. L. et al. (2008) Cancer proliferation gene discovery through functional genomics. Science 319, 620-624 (Pubitemid 351197064)
-
(2008)
Science
, vol.319
, Issue.5863
, pp. 620-624
-
-
Schlabach, M.R.1
Luo, J.2
Solimini, N.L.3
Hu, G.4
Xu, Q.5
Li, M.Z.6
Zhao, Z.7
Smogorzewska, A.8
Sowa, M.E.9
Ang, X.L.10
Westbrook, T.F.11
Liang, A.C.12
Chang, K.13
Hackett, J.A.14
Harper, J.W.15
Hannon, G.J.16
Elledge, S.J.17
-
42
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
DOI 10.1038/nature05610, PII NATURE05610
-
Greenman, C., Stephens, P., Smith, R., Dalgliesh, G. L., Hunter, C., Bignell, G., Davies, H., Teague, J., Butler, A., Stevens, C. et al. (2007) Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158 (Pubitemid 46398669)
-
(2007)
Nature
, vol.446
, Issue.7132
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'Meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
Menzies, A.31
Mironenko, T.32
Perry, J.33
Raine, K.34
Richardson, D.35
Shepherd, R.36
Small, A.37
Tofts, C.38
Varian, J.39
Webb, T.40
West, S.41
Widaa, S.42
Yates, A.43
Cahill, D.P.44
Louis, D.N.45
Goldstraw, P.46
Nicholson, A.G.47
Brasseur, F.48
Looijenga, L.49
Weber, B.L.50
Chiew, Y.-E.51
DeFazio, A.52
Greaves, M.F.53
Green, A.R.54
Campbell, P.55
Birney, E.56
Easton, D.F.57
Chenevix-Trench, G.58
Tan, M.-H.59
Khoo, S.K.60
Teh, B.T.61
Yuen, S.T.62
Leung, S.Y.63
Wooster, R.64
Futreal, P.A.65
Stratton, M.R.66
more..
-
43
-
-
33947188719
-
Cancer: Drivers and passengers
-
DOI 10.1038/446145a, PII 446145A
-
Haber, D. A. and Settleman, J. (2007) Cancer: drivers and passengers. Nature 446, 145-146 (Pubitemid 46398653)
-
(2007)
Nature
, vol.446
, Issue.7132
, pp. 145-146
-
-
Haber, D.A.1
Settleman, J.2
-
44
-
-
77953626646
-
Genomic screening with RNAi: Results and challenges
-
Mohr, S., Bakal, C. and Perrimon, N. (2010) Genomic screening with RNAi: results and challenges. Annu. Rev. Biochem. 79, 37-64
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 37-64
-
-
Mohr, S.1
Bakal, C.2
Perrimon, N.3
-
45
-
-
79951539168
-
Quantification of protein kinase activities by LC-MS
-
Alcolea, M. P. and Cutillas, P. R. (2010) Quantification of protein kinase activities by LC-MS. Methods Mol. Biol. 658, 325-337
-
(2010)
Methods Mol. Biol.
, vol.658
, pp. 325-337
-
-
Alcolea, M.P.1
Cutillas, P.R.2
-
46
-
-
33745159317
-
Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry
-
Cutillas, P. R., Khwaja, A., Graupera, M., Pearce, W., Gharbi, S., Waterfield, M. and Vanhaesebroeck, B. (2006) Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry. Proc. Natl. Acad. Sci. U.S.A. 103, 8959-8964
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 8959-8964
-
-
Cutillas, P.R.1
Khwaja, A.2
Graupera, M.3
Pearce, W.4
Gharbi, S.5
Waterfield, M.6
Vanhaesebroeck, B.7
-
47
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck, B., Leevers, S. J., Ahmadi, K., Timms, J., Katso, R., Driscoll, P. C., Woscholski, R., Parker, P. J. and Waterfield, M. D. (2001) Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70, 535-602
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
48
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley, L. C. (2002) The phosphoinositide 3-kinase pathway. Science 296, 1655-1657
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
49
-
-
33750113074
-
The role of phosphoinositide 3-kinase in human disease
-
Cantley, L. C. (2004) The role of phosphoinositide 3-kinase in human disease. Harvey Lect. 100, 103-122
-
(2004)
Harvey Lect.
, vol.100
, pp. 103-122
-
-
Cantley, L.C.1
-
50
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
-
DOI 10.1016/S0014-5793(96)01370-1, PII S0014579396013701
-
Alessi, D. R., Caudwell, F. B., Andjelkovic, M., Hemmings, B. A. and Cohen, P. (1996) Molecular basis for the substrate specificity of protein kinase B: comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399, 333-338 (Pubitemid 26426877)
-
(1996)
FEBS Letters
, vol.399
, Issue.3
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
51
-
-
0036605838
-
The synthetic peptide RPRAATF allows specific assay of Akt activity in cell lysates
-
Bozinovski, S., Cristiano, B. E., Marmy-Conus, N. and Pearson, R. B. (2002) The synthetic peptide RPRAATF allows specific assay of Akt activity in cell lysates. Anal. Biochem. 305, 32-39
-
(2002)
Anal. Biochem.
, vol.305
, pp. 32-39
-
-
Bozinovski, S.1
Cristiano, B.E.2
Marmy-Conus, N.3
Pearson, R.B.4
-
52
-
-
79951528136
-
Activitomics: Multiplexed quantification of protein kinase activities by mass spectrometry
-
Presentation at the
-
Cutillas, P. (2004) Activitomics: multiplexed quantification of protein kinase activities by mass spectrometry. Presentation at the 52nd ASMS Conference on Mass Spectrometry and Allied Topics, May 23-27, Gaylord Opryland Hotel, Nashville, Tennessee
-
(2004)
52nd ASMS Conference on Mass Spectrometry and Allied Topics, May 23-27, Gaylord Opryland Hotel, Nashville, Tennessee
-
-
Cutillas, P.1
-
53
-
-
70349961430
-
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification
-
Kubota, K., Anjum, R., Yu, Y., Kunz, R. C., Andersen, J. N., Kraus, M., Keilhack, H., Nagashima, K., Krauss, S., Paweletz, C. et al. (2009) Sensitive multiplexed analysis of kinase activities and activity-based kinase identification. Nat. Biotechnol. 27, 933-940
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 933-940
-
-
Kubota, K.1
Anjum, R.2
Yu, Y.3
Kunz, R.C.4
Andersen, J.N.5
Kraus, M.6
Keilhack, H.7
Nagashima, K.8
Krauss, S.9
Paweletz, C.10
-
54
-
-
55749111058
-
Linear motif atlas for phosphorylation-dependent signaling
-
Miller, M. L., Jensen, L. J., Diella, F., Jorgensen, C., Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T. et al. (2008) Linear motif atlas for phosphorylation-dependent signaling. Sci. Signaling 1, ra2
-
(2008)
Sci. Signaling
, vol.1
-
-
Miller, M.L.1
Jensen, L.J.2
Diella, F.3
Jorgensen, C.4
Tinti, M.5
Li, L.6
Hsiung, M.7
Parker, S.A.8
Bordeaux, J.9
Sicheritz-Ponten, T.10
-
55
-
-
77952986553
-
Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs
-
Mok, J., Kim, P. M., Lam, H. Y., Piccirillo, S., Zhou, X., Jeschke, G. R., Sheridan, D. L., Parker, S. A., Desai, V., Jwa, M. et al. (2010) Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Sci. Signaling 3, ra12
-
(2010)
Sci. Signaling
, vol.3
-
-
Mok, J.1
Kim, P.M.2
Lam, H.Y.3
Piccirillo, S.4
Zhou, X.5
Jeschke, G.R.6
Sheridan, D.L.7
Parker, S.A.8
Desai, V.9
Jwa, M.10
-
56
-
-
77956621143
-
Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases
-
Moritz, A., Li, Y., Guo, A., Villen, J., Wang, Y., MacNeill, J., Kornhauser, J., Sprott, K., Zhou, J., Possemato, A. et al. (2010) Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases. Sci. Signaling 3, ra64
-
(2010)
Sci. Signaling
, vol.3
-
-
Moritz, A.1
Li, Y.2
Guo, A.3
Villen, J.4
Wang, Y.5
MacNeill, J.6
Kornhauser, J.7
Sprott, K.8
Zhou, J.9
Possemato, A.10
-
57
-
-
79951548992
-
Approaches and applications of quantitative LC-MS for proteomics and activitomics
-
Cutillas, P. R. and Timms, J. F. (2010) Approaches and applications of quantitative LC-MS for proteomics and activitomics. Methods Mol. Biol. 658, 3-17
-
(2010)
Methods Mol. Biol.
, vol.658
, pp. 3-17
-
-
Cutillas, P.R.1
Timms, J.F.2
-
58
-
-
65549088630
-
Tracing pathway activities with kinase inhibitors and reverse phase protein arrays
-
van Oostrum, J., Calonder, C., Rechsteiner, D., Ehrat, M., Mestan, J., Fabbro, D. and Voshol, H. (2009) Tracing pathway activities with kinase inhibitors and reverse phase protein arrays. Proteomics Clin. Appl. 3, 412-422
-
(2009)
Proteomics Clin. Appl.
, vol.3
, pp. 412-422
-
-
Van Oostrum, J.1
Calonder, C.2
Rechsteiner, D.3
Ehrat, M.4
Mestan, J.5
Fabbro, D.6
Voshol, H.7
-
59
-
-
0030712317
-
Further evidence that the inhibition of glycogen synthase kinase-3β by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216
-
Shaw, M., Cohen, P. and Alessi, D. R. (1997) Further evidence that the inhibition of glycogen synthase kinase-3β by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216. FEBS Lett. 416, 307-311
-
(1997)
FEBS Lett.
, vol.416
, pp. 307-311
-
-
Shaw, M.1
Cohen, P.2
Alessi, D.R.3
-
60
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning, B. D. and Cantley, L. C. (2007) AKT/PKB signaling: navigating downstream. Cell 129, 1261-1274
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
61
-
-
65349155149
-
Weak functional constraints on phosphoproteomes
-
Landry, C. R., Levy, E. D. and Michnick, S. W. (2009) Weak functional constraints on phosphoproteomes. Trends Genet. 25, 193-197
-
(2009)
Trends Genet.
, vol.25
, pp. 193-197
-
-
Landry, C.R.1
Levy, E.D.2
Michnick, S.W.3
-
62
-
-
48149087568
-
Non-functional phosphorylations?
-
Lienhard, G. E. (2008) Non-functional phosphorylations? Trends Biochem. Sci. 33, 351-352
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 351-352
-
-
Lienhard, G.E.1
-
63
-
-
77956625920
-
(R)evolution of complex regulatory systems
-
Linding, R. (2010) (R)evolution of complex regulatory systems. Sci. Signaling 3, eg4
-
(2010)
Sci. Signaling
, vol.3
-
-
Linding, R.1
-
64
-
-
77953563038
-
Roles of 'junk phosphorylation' in modulating biomolecular association of phosphorylated proteins?
-
Tan, C. S., Jorgensen, C. and Linding, R. (2010) Roles of 'junk phosphorylation' in modulating biomolecular association of phosphorylated proteins? Cell Cycle 9, 1276-1280
-
(2010)
Cell Cycle
, vol.9
, pp. 1276-1280
-
-
Tan, C.S.1
Jorgensen, C.2
Linding, R.3
-
65
-
-
68549104477
-
Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets
-
Alcolea, M. P., Kleiner, O. and Cutillas, P. R. (2009) Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets. J. Proteome Res. 8, 3808-3815
-
(2009)
J. Proteome Res.
, vol.8
, pp. 3808-3815
-
-
Alcolea, M.P.1
Kleiner, O.2
Cutillas, P.R.3
-
66
-
-
38549109487
-
NetworKIN: A resource for exploring cellular phosphorylation networks
-
DOI 10.1093/nar/gkm902
-
Linding, R., Jensen, L. J., Pasculescu, A., Olhovsky, M., Colwill, K., Bork, P., Yaffe, M. B. and Pawson, T. (2008) NetworKIN: a resource for exploring cellular phosphorylation networks. Nucleic Acids Res. 36, D695-D699 (Pubitemid 351149809)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.SUPPL. 1
-
-
Linding, R.1
Jensen, L.J.2
Pasculescu, A.3
Olhovsky, M.4
Colwill, K.5
Bork, P.6
Yaffe, M.B.7
Pawson, T.8
-
67
-
-
0242300176
-
Targets of the cyclin-dependent kinase Cdk1
-
Ubersax, J. A., Woodbury, E. L., Quang, P. N., Paraz, M., Blethrow, J. D., Shah, K., Shokat, K. M. and Morgan, D. O. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425, 859-864
-
(2003)
Nature
, vol.425
, pp. 859-864
-
-
Ubersax, J.A.1
Woodbury, E.L.2
Quang, P.N.3
Paraz, M.4
Blethrow, J.D.5
Shah, K.6
Shokat, K.M.7
Morgan, D.O.8
-
68
-
-
77952406753
-
QIKS: Quantitative identification of kinase substrates
-
Morandell, S., Grosstessner-Hain, K., Roitinger, E., Hudecz, O., Lindhorst, T., Teis, D., Wrulich, O. A., Mazanek, M., Taus, T., Ueberall, F. et al. (2010) QIKS: quantitative identification of kinase substrates. Proteomics 10, 2015-2025
-
(2010)
Proteomics
, vol.10
, pp. 2015-2025
-
-
Morandell, S.1
Grosstessner-Hain, K.2
Roitinger, E.3
Hudecz, O.4
Lindhorst, T.5
Teis, D.6
Wrulich, O.A.7
Mazanek, M.8
Taus, T.9
Ueberall, F.10
-
69
-
-
36749080969
-
STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells
-
Onishi, A., Chen, Q., Humtsoe, J. O. and Kramer, R. H. (2008) STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells. Exp. Cell Res. 314, 377-386
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 377-386
-
-
Onishi, A.1
Chen, Q.2
Humtsoe, J.O.3
Kramer, R.H.4
-
70
-
-
77951644400
-
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
-
Olsen, J. V., Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, L. J., Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A. et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci. Signaling 3, ra3
-
(2010)
Sci. Signaling
, vol.3
-
-
Olsen, J.V.1
Vermeulen, M.2
Santamaria, A.3
Kumar, C.4
Miller, M.L.5
Jensen, L.J.6
Gnad, F.7
Cox, J.8
Jensen, T.S.9
Nigg, E.A.10
-
71
-
-
65249137629
-
Global and site-specific quantitative phosphoproteomics: Principles and applications
-
Macek, B., Mann, M. and Olsen, J. V. (2009) Global and site-specific quantitative phosphoproteomics: principles and applications. Annu. Rev. Pharmacol. Toxicol. 49, 199-221
-
(2009)
Annu. Rev. Pharmacol. Toxicol.
, vol.49
, pp. 199-221
-
-
Macek, B.1
Mann, M.2
Olsen, J.V.3
-
72
-
-
79951531728
-
Overview of quantitative LC-MS techniques for proteomics and activitomics
-
Timms, J. F. and Cutillas, P. R. (2010) Overview of quantitative LC-MS techniques for proteomics and activitomics. Methods Mol. Biol. 658, 19-45
-
(2010)
Methods Mol. Biol.
, vol.658
, pp. 19-45
-
-
Timms, J.F.1
Cutillas, P.R.2
-
73
-
-
63049113651
-
Analytical strategies for phosphoproteomics
-
Thingholm, T. E., Jensen, O. N. and Larsen, M. R. (2009) Analytical strategies for phosphoproteomics. Proteomics 9, 1451-1468
-
(2009)
Proteomics
, vol.9
, pp. 1451-1468
-
-
Thingholm, T.E.1
Jensen, O.N.2
Larsen, M.R.3
-
74
-
-
33750336592
-
Quantitative proteomics to study mitogen-activated protein kinases
-
DOI 10.1016/j.ymeth.2006.08.001, PII S1046202306001691
-
Blagoev, B. and Mann, M. (2006) Quantitative proteomics to study mitogen-activated protein kinases. Methods 40, 243-250 (Pubitemid 44635297)
-
(2006)
Methods
, vol.40
, Issue.3
, pp. 243-250
-
-
Blagoev, B.1
Mann, M.2
-
75
-
-
38049184488
-
Profiling of UV-induced ATM/ATR signaling pathways
-
Stokes, M. P., Rush, J., Macneill, J., Ren, J. M., Sprott, K., Nardone, J., Yang, V., Beausoleil, S. A., Gygi, S. P., Livingstone, M. et al. (2007) Profiling of UV-induced ATM/ATR signaling pathways. Proc. Natl. Acad. Sci. U.S.A. 104, 19855-19860
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19855-19860
-
-
Stokes, M.P.1
Rush, J.2
Macneill, J.3
Ren, J.M.4
Sprott, K.5
Nardone, J.6
Yang, V.7
Beausoleil, S.A.8
Gygi, S.P.9
Livingstone, M.10
-
76
-
-
24044467381
-
Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: Analysis of phosphoprotein dynamics in a B cell lymphoma cell line
-
Cutillas, P. R., Geering, B., Waterfield, M. D. and Vanhaesebroeck, B. (2005) Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: analysis of phosphoprotein dynamics in a B cell lymphoma cell line. Mol. Cell. Proteomics 4, 1038-1051
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 1038-1051
-
-
Cutillas, P.R.1
Geering, B.2
Waterfield, M.D.3
Vanhaesebroeck, B.4
-
77
-
-
15344341157
-
Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS
-
Steen, H., Jebanathirajah, J. A., Springer, M. and Kirschner, M. W. (2005) Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS. Proc. Natl. Acad. Sci. U.S.A. 102, 3948-3953
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 3948-3953
-
-
Steen, H.1
Jebanathirajah, J.A.2
Springer, M.3
Kirschner, M.W.4
-
78
-
-
33750456519
-
Global, in Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
-
DOI 10.1016/j.cell.2006.09.026, PII S0092867406012748
-
Olsen, J. V., Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. and Mann, M. (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127, 635-648 (Pubitemid 44647421)
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 635-648
-
-
Olsen, J.V.1
Blagoev, B.2
Gnad, F.3
Macek, B.4
Kumar, C.5
Mortensen, P.6
Mann, M.7
-
79
-
-
70350572219
-
Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling
-
Amanchy, R., Zhong, J., Hong, R., Kim, J. H., Gucek, M., Cole, R. N., Molina, H. and Pandey, A. (2009) Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling. Mol. Oncol. 3, 439-450
-
(2009)
Mol. Oncol.
, vol.3
, pp. 439-450
-
-
Amanchy, R.1
Zhong, J.2
Hong, R.3
Kim, J.H.4
Gucek, M.5
Cole, R.N.6
Molina, H.7
Pandey, A.8
-
80
-
-
40649117198
-
Dissection of the insulin signaling pathway via quantitative phosphoproteomics
-
Kruger, M., Kratchmarova, I., Blagoev, B., Tseng, Y. H., Kahn, C. R. and Mann, M. (2008) Dissection of the insulin signaling pathway via quantitative phosphoproteomics. Proc. Natl. Acad. Sci. U.S.A. 105, 2451-2456
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 2451-2456
-
-
Kruger, M.1
Kratchmarova, I.2
Blagoev, B.3
Tseng, Y.H.4
Kahn, C.R.5
Mann, M.6
-
81
-
-
34948875686
-
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
-
Bantscheff, M., Eberhard, D., Abraham, Y., Bastuck, S., Boesche, M., Hobson, S., Mathieson, T., Perrin, J., Raida, M., Rau, C. et al. (2007) Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat. Biotechnol. 25, 1035-1044
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1035-1044
-
-
Bantscheff, M.1
Eberhard, D.2
Abraham, Y.3
Bastuck, S.4
Boesche, M.5
Hobson, S.6
Mathieson, T.7
Perrin, J.8
Raida, M.9
Rau, C.10
-
82
-
-
76649110554
-
In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling
-
Boersema, P. J., Foong, L. Y., Ding, V. M., Lemeer, S., van Breukelen, B., Philp, R., Boekhorst, J., Snel, B., den Hertog, J., Choo, A. B. and Heck, A. J. (2009) In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling. Mol. Cell. Proteomics 9, 84-99
-
(2009)
Mol. Cell. Proteomics
, vol.9
, pp. 84-99
-
-
Boersema, P.J.1
Foong, L.Y.2
Ding, V.M.3
Lemeer, S.4
Van Breukelen, B.5
Philp, R.6
Boekhorst, J.7
Snel, B.8
Den Hertog, J.9
Choo, A.B.10
Heck, A.J.11
-
83
-
-
26844576371
-
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules
-
Zhang, Y., Wolf-Yadlin, A., Ross, P. L., Pappin, D. J., Rush, J., Lauffenburger, D. A. and White, F. M. (2005) Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Mol. Cell. Proteomics 4, 1240-1250
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 1240-1250
-
-
Zhang, Y.1
Wolf-Yadlin, A.2
Ross, P.L.3
Pappin, D.J.4
Rush, J.5
Lauffenburger, D.A.6
White, F.M.7
-
84
-
-
0037795741
-
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
-
Gerber, S. A., Rush, J., Stemman, O., Kirschner, M. W. and Gygi, S. P. (2003) Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Proc. Natl. Acad. Sci. U.S.A. 100, 6940-6945
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 6940-6945
-
-
Gerber, S.A.1
Rush, J.2
Stemman, O.3
Kirschner, M.W.4
Gygi, S.P.5
-
85
-
-
44149105911
-
PHOSIDA (phosphorylation site database): Management, structural and evolutionary investigation, and prediction of phosphosites
-
Gnad, F., Ren, S., Cox, J., Olsen, J. V., Macek, B., Oroshi, M. and Mann, M. (2007) PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites. Genome Biol. 8, R250
-
(2007)
Genome Biol.
, vol.8
-
-
Gnad, F.1
Ren, S.2
Cox, J.3
Olsen, J.V.4
Macek, B.5
Oroshi, M.6
Mann, M.7
-
86
-
-
38549092088
-
Phospho. ELM: A database of phosphorylation sites: Update 2008
-
Diella, F., Gould, C. M., Chica, C., Via, A. and Gibson, T. J. (2008) Phospho. ELM: a database of phosphorylation sites: update 2008. Nucleic Acids Res. 36, D240-D244
-
(2008)
Nucleic Acids Res.
, vol.36
-
-
Diella, F.1
Gould, C.M.2
Chica, C.3
Via, A.4
Gibson, T.J.5
-
87
-
-
2942598149
-
PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation
-
DOI 10.1002/pmic.200300772
-
Hornbeck, P. V., Chabra, I., Kornhauser, J. M., Skrzypek, E. and Zhang, B. (2004) PhosphoSite: a bioinformatics resource dedicated to physiological protein phosphorylation. Proteomics 4, 1551-1561 (Pubitemid 38738314)
-
(2004)
Proteomics
, vol.4
, Issue.6
, pp. 1551-1561
-
-
Hornbeck, P.V.1
Chabra, I.2
Kornhauser, J.M.3
Skrzypek, E.4
Zhang, B.5
-
88
-
-
79951543918
-
Tranche distributed repository and ProteomeCommons.org
-
Smith, B. E., Hill, J. A., Gjukich, M. A. and Andrews, P. C. (2010) Tranche distributed repository and ProteomeCommons.org. Methods Mol. Biol. 696, 123-145
-
(2010)
Methods Mol. Biol.
, vol.696
, pp. 123-145
-
-
Smith, B.E.1
Hill, J.A.2
Gjukich, M.A.3
Andrews, P.C.4
-
89
-
-
77957220208
-
Proteomics data repositories: Providing a safe haven for your data and acting as a springboard for further research
-
Vizcaino, J. A., Foster, J. M. and Martens, L. (2010) Proteomics data repositories: providing a safe haven for your data and acting as a springboard for further research. J. Proteomics 73, 2136-2146
-
(2010)
J. Proteomics
, vol.73
, pp. 2136-2146
-
-
Vizcaino, J.A.1
Foster, J.M.2
Martens, L.3
-
90
-
-
68049101085
-
Application of label-free quantitative peptidomics for the identification of urinary biomarkers of kidney chronic allograft dysfunction
-
Quintana, L. F., Campistol, J. M., Alcolea, M. P., Banon-Maneus, E., Sol-Gonzalez, A. and Cutillas, P. R. (2009) Application of label-free quantitative peptidomics for the identification of urinary biomarkers of kidney chronic allograft dysfunction. Mol. Cell. Proteomics 8, 1658-1673
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 1658-1673
-
-
Quintana, L.F.1
Campistol, J.M.2
Alcolea, M.P.3
Banon-Maneus, E.4
Sol-Gonzalez, A.5
Cutillas, P.R.6
-
91
-
-
46049096420
-
Drug testing
-
Cowan, D. A. (2008) Drug testing. Essays Biochem. 44, 139-148
-
(2008)
Essays Biochem.
, vol.44
, pp. 139-148
-
-
Cowan, D.A.1
-
92
-
-
33645721632
-
Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins
-
Anderson, L. and Hunter, C. L. (2006) Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins. Mol. Cell. Proteomics 5, 573-588
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 573-588
-
-
Anderson, L.1
Hunter, C.L.2
-
93
-
-
67650564834
-
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma
-
Addona, T. A., Abbatiello, S. E., Schilling, B., Skates, S. J., Mani, D. R., Bunk, D. M., Spiegelman, C. H., Zimmerman, L. J., Ham, A. J., Keshishian, H. et al. (2009) Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat. Biotechnol. 27, 633-641
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 633-641
-
-
Addona, T.A.1
Abbatiello, S.E.2
Schilling, B.3
Skates, S.J.4
Mani, D.R.5
Bunk, D.M.6
Spiegelman, C.H.7
Zimmerman, L.J.8
Ham, A.J.9
Keshishian, H.10
-
94
-
-
34250722602
-
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks
-
Wolf-Yadlin, A., Hautaniemi, S., Lauffenburger, D. A. and White, F. M. (2007) Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Proc. Natl. Acad. Sci. U.S.A. 104, 5860-5865
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 5860-5865
-
-
Wolf-Yadlin, A.1
Hautaniemi, S.2
Lauffenburger, D.A.3
White, F.M.4
-
95
-
-
79953227740
-
Increased selectivity, analytical precision, and throughput in targeted proteomics
-
doi: 10.1074/mcp.M110.002931
-
Kiyonami, R., Schoen, A., Prakash, A., Peterman, S., Zabrouskov, V., Picotti, P., Aebersold, R., Huhmer, A. and Domon, B. (2010) Increased selectivity, analytical precision, and throughput in targeted proteomics. Mol. Cell. Proteomics, doi: 10.1074/mcp.M110.002931
-
(2010)
Mol. Cell. Proteomics
-
-
Kiyonami, R.1
Schoen, A.2
Prakash, A.3
Peterman, S.4
Zabrouskov, V.5
Picotti, P.6
Aebersold, R.7
Huhmer, A.8
Domon, B.9
-
96
-
-
34848822499
-
Quantitative profile of five murine core proteomes using label-free functional proteomics
-
Cutillas, P. R. and Vanhaesebroeck, B. (2007) Quantitative profile of five murine core proteomes using label-free functional proteomics. Mol. Cell. Proteomics 6, 1560-1573
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 1560-1573
-
-
Cutillas, P.R.1
Vanhaesebroeck, B.2
-
97
-
-
36348975222
-
Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition
-
DOI 10.1021/pr070068e
-
Yang, F., Jaitly, N., Jayachandran, H., Luo, Q., Monroe, M. E., Du, X., Gritsenko, M. A., Zhang, R., Anderson, D. J., Purvine, S. O. et al. (2007) Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition. J. Proteome Res. 6, 4489-4497 (Pubitemid 350158524)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.11
, pp. 4489-4497
-
-
Yang, F.1
Jaitly, N.2
Jayachandran, H.3
Luo, Q.4
Monroe, M.E.5
Du, X.6
Gritsenko, M.A.7
Zhang, R.8
Anderson, D.J.9
Purvine, S.O.10
Adkins, J.N.11
Moore, R.J.12
Mottaz, H.M.13
Ding, S.-J.14
Lipton, M.S.15
Camp II, D.G.16
Udseth, H.R.17
Smith, R.D.18
Rossie, S.19
-
98
-
-
41549117597
-
A quantitative analysis software tool for mass spectrometry-based proteomics
-
DOI 10.1038/nmeth.1195, PII NMETH.1195
-
Park, S. K., Venable, J. D., Xu, T. and Yates, 3rd, J. R. (2008) A quantitative analysis software tool for mass spectrometry-based proteomics. Nat. Methods 5, 319-322 (Pubitemid 351459367)
-
(2008)
Nature Methods
, vol.5
, Issue.4
, pp. 319-322
-
-
Park, S.K.1
Venable, J.D.2
Xu, T.3
Yates III, J.R.4
-
99
-
-
78651083717
-
A self-validating quantitative mass spectrometry method for assessing the accuracy of high-content phosphoproteomic experiments
-
Casado, P. and Cutillas, P. R. (2011) A self-validating quantitative mass spectrometry method for assessing the accuracy of high-content phosphoproteomic experiments. Mol. Cell. Proteomics 10, M110.003079
-
(2011)
Mol. Cell. Proteomics
, vol.10
-
-
Casado, P.1
Cutillas, P.R.2
|