Further evidence that the inhibition of glycogen synthase kinase-3β by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

FEBS Letters

Volumn 416, Issue 3, 1997, Pages 307-311

  Shaw, Morag ^a   Cohen, Philip ^a   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

3 Phosphoinositide dependent protein kinase; Glycogen synthase; Glycogen synthase kinase 3; Insulin; Insulin like growth factor 1; Protein kinase B

Indexed keywords

INSULIN; PROTEIN KINASE; SOMATOMEDIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MUTANT; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ALANINE; AMINO ACID SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; ISOENZYMES; MUTAGENESIS, SITE-DIRECTED; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTYROSINE; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SERINE; TRANSFECTION; TYROSINE;

ANIMALIA;

EID: 0030712317     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01235-0     Document Type: Article

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