Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 24, 2006, Pages 8959-8964

  Cutillas, Pedro R ^a,b   Khwaja, Asim ^c   Graupera, Mariona ^a   Pearce, Wayne ^a   Gharbi, Severine ^a   Waterfield, Mike ^a,b   Vanhaesebroeck, Bart ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cancer stem cells; Patient stratification; Personalized therapies; Quantitative analysis; Signaling pathway

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER THERAPY; CANCER TISSUE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE AMPLIFICATION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

EID: 33745159317     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0602101103     Document Type: Article

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