-
1
-
-
34748837360
-
Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis
-
Katoh, M. Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev., 2007, 3, 30-38.
-
(2007)
Stem Cell Rev
, vol.3
, pp. 30-38
-
-
Katoh, M.1
-
2
-
-
23244448347
-
Expression pattern of Wnt signaling components in the adult intestine
-
Gregorieff, A.; Pinto, D.; Begthel, H.; Destrée, O.; Kielman, M.; Clevers, H. Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology, 2005, 129, 626-638.
-
(2005)
Gastroenterology
, vol.129
, pp. 626-638
-
-
Gregorieff, A.1
Pinto, D.2
Begthel, H.3
Destrée, O.4
Kielman, M.5
Clevers, H.6
-
3
-
-
43049144313
-
Wnt signaling and stem cell control
-
Nusse, R. Wnt signaling and stem cell control. Cell Res., 2008, 18, 523-527.
-
(2008)
Cell Res
, vol.18
, pp. 523-527
-
-
Nusse, R.1
-
4
-
-
67449150167
-
A Wnt survival guide: From flies to human disease
-
Chien, A. J.; Conrad, W. H.; Moon, R. T. A Wnt survival guide: from flies to human disease. J. Invest. Dermatol., 2009, 129, 1614-1627.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 1614-1627
-
-
Chien, A.J.1
Conrad, W.H.2
Moon, R.T.3
-
5
-
-
34547107319
-
WNT signaling pathway and stem cell signaling network
-
Katoh, M.; Katoh, M. WNT signaling pathway and stem cell signaling network. Clin. Cancer Res., 2007, 13, 4042-4045.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 4042-4045
-
-
Katoh, M.1
Katoh, M.2
-
6
-
-
18144415072
-
Mechanisms underlying differential responses to FGF signaling
-
Dailey, L.; Ambrosetti, D.; Mansukhani, A.; Basilico, C. Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev., 2005, 16, 233-247.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 233-247
-
-
Dailey, L.1
Ambrosetti, D.2
Mansukhani, A.3
Basilico, C.4
-
7
-
-
67651121761
-
FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies
-
Katoh, M. FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies. J. Invest. Dermatol., 2009, 129, 1862-1867.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 1862-1867
-
-
Katoh, M.1
-
8
-
-
78349232462
-
Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases
-
Bae, J. H.; Schlessinger, J. Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases. Mol. Cells, 2010, 29, 443-448.
-
(2010)
Mol. Cells
, vol.29
, pp. 443-448
-
-
Bae, J.H.1
Schlessinger, J.2
-
9
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumor suppressor?
-
Radtke, F.; Raj, K. The role of Notch in tumorigenesis: Oncogene or tumor suppressor? Nat. Rev. Cancer, 2003, 3, 765-767.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 765-767
-
-
Radtke, F.1
Raj, K.2
-
10
-
-
33644782668
-
Recent insight into the role of Notch signaling in tumorigenesis
-
Leong, K. G.; Karsan A. Recent insight into the role of Notch signaling in tumorigenesis. Blood, 2006, 107, 2223-2233.
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
11
-
-
34748828940
-
Notch signaling in gastrointestinal tract
-
Katoh, M.; Katoh, M. Notch signaling in gastrointestinal tract. Int. J. Oncol., 2007, 30, 247-251.
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 247-251
-
-
Katoh, M.1
Katoh, M.2
-
12
-
-
44449149171
-
Dynamic control of TGF β signaling and its links to the cytoskeleton
-
Moustakas, A.; Heldin, C. H. Dynamic control of TGF β signaling and its links to the cytoskeleton. FEBS Lett., 2008, 582, 2051-2065.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2051-2065
-
-
Moustakas, A.1
Heldin, C.H.2
-
13
-
-
47549090432
-
TGFβ in cancer
-
Massagué, J. TGFβ in cancer. Cell, 2008, 134, 215-230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
14
-
-
2942738996
-
The Hedgehog response network: Sensors, switches, and routers
-
Lum, L.; Beachy, P. A. The Hedgehog response network: sensors, switches, and routers. Science, 2004, 304, 1755-1759.
-
(2004)
Science
, vol.304
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
15
-
-
27744583597
-
Hedgehog signaling in gastric cancer
-
Katoh, Y.; Katoh, M. Hedgehog signaling in gastric cancer. Cancer Biol. Ther., 2005, 4, 1050-1054.
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 1050-1054
-
-
Katoh, Y.1
Katoh, M.2
-
16
-
-
53549125545
-
A genomescale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
-
Vokes, S. A.; Ji, H.; Wong, W. H.; McMahon, A.P. A genomescale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes Dev., 2008, 22, 2651-2663.
-
(2008)
Genes Dev
, vol.22
, pp. 2651-2663
-
-
Vokes, S.A.1
Ji, H.2
Wong, W.H.3
McMahon, A.P.4
-
17
-
-
77953316514
-
Mechanism and evolution of cytosolic Hedgehog signal transduction
-
Wilson, C. W.; Chuang, P. T. Mechanism and evolution of cytosolic Hedgehog signal transduction. Development, 2010, 137, 2079-2094.
-
(2010)
Development
, vol.137
, pp. 2079-2094
-
-
Wilson, C.W.1
Chuang, P.T.2
-
18
-
-
0242381919
-
WNT and FGF gene clusters
-
Katoh, M. WNT and FGF gene clusters. Int. J. Oncol., 2002, 21, 1269-1273.
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 1269-1273
-
-
Katoh, M.1
-
19
-
-
0344464720
-
Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
-
Nusse, R. Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development, 2003, 130, 5297-5305.
-
(2003)
Development
, vol.130
, pp. 5297-5305
-
-
Nusse, R.1
-
20
-
-
33947521050
-
Helping Wingless take flight: How WNT proteins are secreted
-
Hausmann, G.; Bänziger, C.; Basler, K. Helping Wingless take flight: how WNT proteins are secreted. Nat. Rev. Mol. Cell Biol., 2007, 8, 331-336.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 331-336
-
-
Hausmann, G.1
Bänziger, C.2
Basler, K.3
-
21
-
-
0033584401
-
Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family
-
Koike, J.; Takagi, A.; Miwa, T.; Hira,i M.; Terada, M.; Katoh, M. Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family. Biochem. Biophys. Res. Commun., 1999, 262, 39-43.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 39-43
-
-
Koike, J.1
Takagi, A.2
Miwa, T.3
Terada, M.4
Katoh, M.5
-
22
-
-
42149181885
-
Structural diversity of G proteincoupled receptors and significance for drug discovery
-
Lagerström, M. C.; Schiöth, H. B. Structural diversity of G proteincoupled receptors and significance for drug discovery. Nat. Rev. Drug Discov., 2008, 7, 339-357.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 339-357
-
-
Lagerström, M.C.1
Schiöth, H.B.2
-
23
-
-
73949153978
-
Wnt modulators in the biotech pipeline
-
Rey, J. P.; Ellies, D. L. Wnt modulators in the biotech pipeline. Dev. Dyn., 2010, 239, 102-114.
-
(2010)
Dev. Dyn.
, vol.239
, pp. 102-114
-
-
Rey, J.P.1
Ellies, D.L.2
-
24
-
-
77953288698
-
Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with β-catenin
-
Fan, X. S.; Wu, H. Y.; Yu, H. P.; Zhou, Q.; Zhang, Y. F.; Huang, Q. Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with β-catenin. Int. J. Colorectal Dis., 2010, 25, 583-590.
-
(2010)
Int. J. Colorectal Dis.
, vol.25
, pp. 583-590
-
-
Fan, X.S.1
Wu, H.Y.2
Yu, H.P.3
Zhou, Q.4
Zhang, Y.F.5
Huang, Q.6
-
25
-
-
42949121156
-
Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
-
Fukuda, T.; Chen, L.; Endo, T.; Tang, L.; Lu, D.; Castro, J. E.; Widhopf, G. F2nd.; Rassenti, L. Z.; Cantwell, M. J.; Prussak, C. E.; Carson, D. A.; Kipps, T. J. Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a. Proc. Natl. Acad. Sci. USA, 2008, 105, 3047-3052.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3047-3052
-
-
Fukuda, T.1
Chen, L.2
Endo, T.3
Tang, L.4
Lu, D.5
Castro, J.E.6
Widhopf, G.7
Rassenti, L.Z.8
Cantwell, M.J.9
Prussak, C.E.10
Carson, D.A.11
Kipps, T.J.12
-
26
-
-
70350100352
-
Hear the Wnt Ror: How melanoma cells adjust to changes in Wnt
-
O'Connell, M. P.; Weeraratna, A.T. Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt. Pig. Cell Melanoma Res., 2009, 22, 724-739.
-
(2009)
Pig. Cell Melanoma Res
, vol.22
, pp. 724-739
-
-
O'Connell, M.P.1
Weeraratna, A.T.2
-
27
-
-
73949156925
-
Ror-family receptor tyrosine kinases in non-canonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
-
Minami, Y.; Oishi, I.; Endo, M.; Nishita, M. Ror-family receptor tyrosine kinases in non-canonical Wnt signaling: their implications in developmental morphogenesis and human diseases. Dev. Dyn., 2010, 239, 1-15.
-
(2010)
Dev. Dyn
, vol.239
, pp. 1-15
-
-
Minami, Y.1
Oishi, I.2
Endo, M.3
Nishita, M.4
-
28
-
-
77950190313
-
Role of secreted frizzled-related protein 3 in human renal cell carcinoma
-
Hirata, H.; Hinoda, Y.; Ueno, K.; Majid, S.; Saini, S.; Dahiya, R. Role of secreted frizzled-related protein 3 in human renal cell carcinoma. Cancer Res., 2010, 70, 1896-1905.
-
(2010)
Cancer Res
, vol.70
, pp. 1896-1905
-
-
Hirata, H.1
Hinoda, Y.2
Ueno, K.3
Majid, S.4
Saini, S.5
Dahiya, R.6
-
29
-
-
78149357406
-
Transcriptional down-regulation of the Wnt antagonist SFRP1 in haematopoietic cells of patients with different risk types of MDS
-
Reins, J.; Mossner, M.; Neumann, M.; Platzbecker, U.; Schumann, C.; Thiel, E.; Hofmann, W.K. Transcriptional down-regulation of the Wnt antagonist SFRP1 in haematopoietic cells of patients with different risk types of MDS. Leuk. Res., 2010, 34(12), 1610-1616.
-
(2010)
Leuk. Res.
, vol.34
, Issue.12
, pp. 1610-1616
-
-
Reins, J.1
Mossner, M.2
Neumann, M.3
Platzbecker, U.4
Schumann, C.5
Thiel, E.6
Hofmann, W.K.7
-
30
-
-
46049083566
-
Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex
-
Yamamoto, S.; Nishimura, O.; Misaki, K.; Nishita, M.; Minami, Y.; Yonemura, S.; Tarui, H.; Sasaki, H. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev. Cell, 2008, 15, 23-36.
-
(2008)
Dev. Cell
, vol.15
, pp. 23-36
-
-
Yamamoto, S.1
Nishimura, O.2
Misaki, K.3
Nishita, M.4
Minami, Y.5
Yonemura, S.6
Tarui, H.7
Sasaki, H.8
-
31
-
-
33845352082
-
Wnts as ligands: Processing, secretion and reception
-
Mikels, A. J.; Nusse, R. Wnts as ligands: processing, secretion and reception. Oncogene, 2006, 25, 7461-7468.
-
(2006)
Oncogene
, vol.25
, pp. 7461-7468
-
-
Mikels, A.J.1
Nusse, R.2
-
32
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers, S.; Moon, R.T. Proximal events in Wnt signal transduction. Nat. Rev. Mol. Cell Biol., 2009, 10, 468-477.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
33
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin, P. J.; Sparks, A. B.; Korinek, V.; Barker, N.; Clevers, H.; Vogelstein, B.; Kinzler, K.W. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science, 1997, 275, 1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
34
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker, N.; Clevers, H. Mining the Wnt pathway for cancer therapeutics. Nat. Rev. Drug Discov., 2006, 5, 997-1014.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
35
-
-
0030800831
-
Three-dimensional structure of the armadillo repeat region of β-catenin
-
Huber, A. H.; Nelson, W. J.; Weis, W.I. Three-dimensional structure of the armadillo repeat region of β-catenin. Cell, 1997, 90, 871-882.
-
(1997)
Cell
, vol.90
, pp. 871-882
-
-
Huber, A.H.1
Nelson, W.J.2
Weis, W.I.3
-
36
-
-
0142106808
-
Armadillo repeat proteins: Beyond the animal kingdom
-
Coates, J. C. Armadillo repeat proteins: beyond the animal kingdom. Trends Cell Biol., 2003, 13, 463-471.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 463-471
-
-
Coates, J.C.1
-
37
-
-
62849106337
-
β-catenin hits chromatin: Regulation of Wnt target gene activation
-
Mosimann, C.; Hausmann, G.; Basler, K. β-catenin hits chromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell Biol., 2009, 10, 276-286.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 276-286
-
-
Mosimann, C.1
Hausmann, G.2
Basler, K.3
-
38
-
-
33845351956
-
β-catenin destruction complex: Insights and questions from a structural perspective
-
Kimelman, D.; Xu, W. β-catenin destruction complex: insights and questions from a structural perspective. Oncogene, 2006, 25, 7482-7491.
-
(2006)
Oncogene
, vol.25
, pp. 7482-7491
-
-
Kimelman, D.1
Xu, W.2
-
39
-
-
73949093736
-
Regulation of Wnt/β-catenin signaling by protein kinases
-
Verheyen, E. M.; Gottardi, C.J. Regulation of Wnt/β-catenin signaling by protein kinases. Dev. Dyn., 2010, 239, 34-44.
-
(2010)
Dev. Dyn
, vol.239
, pp. 34-44
-
-
Verheyen, E.M.1
Gottardi, C.J.2
-
40
-
-
0034607129
-
Molecular cloning and genomic structure of the βTRCP2 gene on chromosome 5q35.1
-
Koike, J.; Sagara, N.; Kirikoshi, H.; Takagi, A.; Miwa, T.; Hirai, M.; Katoh, M. Molecular cloning and genomic structure of the βTRCP2 gene on chromosome 5q35.1. Biochem. Biophys. Res. Commun., 2000, 269, 103-109.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.269
, pp. 103-109
-
-
Koike, J.1
Sagara, N.2
Kirikoshi, H.3
Takagi, A.4
Miwa, T.5
Hirai, M.6
Katoh, M.7
-
41
-
-
85047697637
-
Inhibition of HOS expression and activities by Wnt pathway
-
Spiegelman, V. S.; Tang, W.; Katoh, M.; Slaga, T. J.; Fuchs, S. Y. Inhibition of HOS expression and activities by Wnt pathway. Oncogene, 2002, 21, 856-860.
-
(2002)
Oncogene
, vol.21
, pp. 856-860
-
-
Spiegelman, V.S.1
Tang, W.2
Katoh, M.3
Slaga, T.J.4
Fuchs, S.Y.5
-
42
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: Tipping the scales of cancer
-
Frescas, D.; Pagano, M. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer. Nat. Rev. Cancer, 2008, 8, 438-449.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
43
-
-
0344413477
-
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the Cterminal region of Frizzled
-
Wong, H. C.; Bourdelas, A.; Krauss, A.; Lee, H. J.; Shao, Y.; Wu, D.; Mlodzik, M.; Shi, D. L.; Zheng, J. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the Cterminal region of Frizzled. Mol. Cell, 2003, 12, 1251-1260.
-
(2003)
Mol. Cell
, vol.12
, pp. 1251-1260
-
-
Wong, H.C.1
Bourdelas, A.2
Krauss, A.3
Lee, H.J.4
Shao, Y.5
Wu, D.6
Mlodzik, M.7
Shi, D.L.8
Zheng, J.9
-
44
-
-
0037343952
-
Wg/Wnt signal can be transmitted through arrow/ LRP5,6 and Axin independently of Zw3/Gsk3β activity
-
Tolwinski, N. S.; Wehrli, M.; Rives, A.; Erdeniz, N.; DiNardo, S.; Wieschaus, E. Wg/Wnt signal can be transmitted through arrow/ LRP5,6 and Axin independently of Zw3/Gsk3β activity. Dev. Cell, 2003, 4, 407-418.
-
(2003)
Dev. Cell
, vol.4
, pp. 407-418
-
-
Tolwinski, N.S.1
Wehrli, M.2
Rives, A.3
Erdeniz, N.4
Dinardo, S.5
Wieschaus, E.6
-
45
-
-
0032501156
-
Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7
-
Sagara, N.; Toda, G.; Hirai, M.; Terada, M.; Katoh, M. Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7. Biochem. Biophys. Res. Commun., 1998, 252, 117-122.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.252
, pp. 117-122
-
-
Sagara, N.1
Toda, G.2
Hirai, M.3
Terada, M.4
Katoh, M.5
-
46
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert, J.; Epping, M.; Pollack, J. R.; Brown, P. O.; Nusse, R.A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev. Biol., 2002, 2, 8.
-
(2002)
BMC Dev. Biol.
, vol.2
, pp. 8
-
-
Willert, J.1
Epping, M.2
Pollack, J.R.3
Brown, P.O.4
Nusse, R.5
-
47
-
-
13244299109
-
FGF20 and DKK1 are transcriptional targets of β-catenin and FGF20 is implicated in cancer and development
-
Chamorro, M. N.; Schwartz, D. R.; Vonica, A.; Brivanlou, A. H.; Cho, K. R.; Varmus, H. E. FGF20 and DKK1 are transcriptional targets of β-catenin and FGF20 is implicated in cancer and development. EMBO J., 2005, 24, 73-84.
-
(2005)
EMBO J
, vol.24
, pp. 73-84
-
-
Chamorro, M.N.1
Schwartz, D.R.2
Vonica, A.3
Brivanlou, A.H.4
Cho, K.R.5
Varmus, H.E.6
-
48
-
-
0033636775
-
Wnt/β-catenin signaling induces the expression and activity of βTrCP ubiquitin ligase receptor
-
Spiegelman, V. S.; Slaga, T. J.; Pagano, M.; Minamoto, T.; Ronai, Z.; Fuchs, S.Y. Wnt/β-catenin signaling induces the expression and activity of βTrCP ubiquitin ligase receptor. Mol. Cell, 2000, 5, 877-882.
-
(2000)
Mol. Cell
, vol.5
, pp. 877-882
-
-
Spiegelman, V.S.1
Slaga, T.J.2
Pagano, M.3
Minamoto, T.4
Ronai, Z.5
Fuchs, S.Y.6
-
49
-
-
0035650678
-
Molecular cloning and characterization of human WNT11
-
Kirikoshi, H.; Sekihara, H.; Katoh, M. Molecular cloning and characterization of human WNT11. Int. J. Mol. Med., 2001, 8, 651-656.
-
(2001)
Int. J. Mol. Med.
, vol.8
, pp. 651-656
-
-
Kirikoshi, H.1
Sekihara, H.2
Katoh, M.3
-
50
-
-
34250888462
-
β-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis
-
Lin, L.; Cui, L.; Zhou, W.; Dufort, D.; Zhang, X.; Cai, C.L.; Bu, L.; Yang, L.; Martin, J.; Kemler, R.; Rosenfeld, M. G.; Chen, J.; Evans, S. M. β-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc. Natl. Acad. Sci. USA, 2007, 104, 9313-9318.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9313-9318
-
-
Lin, L.1
Cui, L.2
Zhou, W.3
Dufort, D.4
Zhang, X.5
Cai, C.L.6
Bu, L.7
Yang, L.8
Martin, J.9
Kemler, R.10
Rosenfeld, M.G.11
Chen, J.12
Evans, S.M.13
-
51
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He, T. C.; Sparks, A. B.; Rago, C.; Hermeking, H.; Zawel, L.; da Costa, L. T.; Morin, P. J.; Vogelstein, B.; Kinzler, K. W. Identification of c-MYC as a target of the APC pathway. Science, 1998, 281, 1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
52
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu, O.; McCormick, F. β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature, 1999, 398, 422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
53
-
-
0034596239
-
Molecular cloning and characterization of human FGF20 on chromosome
-
Kirikoshi, H.; Sagara, N.; Saitoh, T.; Tanaka, K.; Sekihara, H.; Shiokawa, K.; Katoh, M. Molecular cloning and characterization of human FGF20 on chromosome 8p21.3-p22. Biochem. Biophys. Res. Commun., 2000, 274, 337-343.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.274
, pp. 337-343
-
-
Kirikoshi, H.1
Sagara, N.2
Saitoh, T.3
Tanaka, K.4
Sekihara, H.5
Shiokawa, K.6
Katoh, M.7
-
54
-
-
33746765208
-
Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells
-
Katoh, M.; Katoh, M. Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells. Int. J. Mol. Med., 2006, 17, 681-685.
-
(2006)
Int. J. Mol. Med.
, vol.17
, pp. 681-685
-
-
Katoh, M.1
Katoh, M.2
-
55
-
-
10744228797
-
Identification of BAMBI, an inhibitor of TGFβ signaling, as a target of the β-catenin pathway in colorectal tumor cells
-
Sekiya, T.; Adachi, S.; Kohu, K.; Yamada, T.; Higuchi, O.; Furukawa, Y.; Nakamura, Y.; Nakamura, T.; Tashiro, K.; Kuhara, S.; Ohwada, S.; Akiyama, T. Identification of BAMBI, an inhibitor of TGFβ signaling, as a target of the β-catenin pathway in colorectal tumor cells. J. Biol. Chem., 2004, 279, 6840-6846.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6840-6846
-
-
Sekiya, T.1
Adachi, S.2
Kohu, K.3
Yamada, T.4
Higuchi, O.5
Furukawa, Y.6
Nakamura, Y.7
Nakamura, T.8
Tashiro, K.9
Kuhara, S.10
Ohwada, S.11
Akiyama, T.12
-
56
-
-
0041695485
-
A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling
-
Veeman, M. T.; Axelrod, J. D.; Moon, R. T. A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev. Cell, 2003, 5, 367-377.
-
(2003)
Dev. Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
57
-
-
33644698339
-
WNT/PCP signaling pathway and human cancer
-
Katoh, M. WNT/PCP signaling pathway and human cancer. Oncol. Rep., 2005, 14, 1583-1588.
-
(2005)
Oncol. Rep
, vol.14
, pp. 1583-1588
-
-
Katoh, M.1
-
58
-
-
42349093195
-
Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
-
Witze, E. S.; Litman, E. S.; Argast, G. M.; Moon, R. T.; Ahn, N. G. Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. Science, 2008, 320, 365-369.
-
(2008)
Science
, vol.320
, pp. 365-369
-
-
Witze, E.S.1
Litman, E.S.2
Argast, G.M.3
Moon, R.T.4
Ahn, N.G.5
-
59
-
-
34347376485
-
Dishevelled promotes axon differentiation by regulating aPKC
-
Zhang, X.; Zhu, J.; Yang, G. Y.; Wang, Q. J.; Qian, L.; Chen, Y. M.; Chen, F.; Tao, Y.; Hu, H. S.; Wang, T.; Luo, Z. G. Dishevelled promotes axon differentiation by regulating aPKC. Nat. Cell Biol., 2007, 9, 743-754.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 743-754
-
-
Zhang, X.1
Zhu, J.2
Yang, G.Y.3
Wang, Q.J.4
Qian, L.5
Chen, Y.M.6
Chen, F.7
Tao, Y.8
Hu, H.S.9
Wang, T.10
Luo, Z.G.11
-
60
-
-
33746990262
-
Wnt5a/Ca2+-induced NFAT activity is counteracted by Wnt5a/Yes-Cdc42-CK1β signaling in human mammary epithelial cells
-
Dejmek, J.; Säfholm, A.; Kamp Nielsen, C.; Andersson, T.; Leandersson, K. Wnt5a/Ca2+-induced NFAT activity is counteracted by Wnt5a/Yes-Cdc42-CK1β signaling in human mammary epithelial cells. Mol. Cell. Biol., 2006, 26, 6024-6036.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6024-6036
-
-
Dejmek, J.1
Säfholm, A.2
Kamp Nielsen, C.3
Andersson, T.4
Leandersson, K.5
-
61
-
-
0033600239
-
The TAK1-NLK pathway antagonizes signalling between β-catenin and transcription factor TCF
-
Ishitani, T.; Ninomiya-Tsuji, J.; Nagai, S.; Nishita, M.; Meneghini, M.; Barker, N.; Waterman, M.; Bowerman, B.; Clevers, H.; Shibuya, H.; Matsumoto, K. The TAK1-NLK pathway antagonizes signalling between β-catenin and transcription factor TCF. Nature, 1999, 399, 798-802.
-
(1999)
Nature
, vol.399
, pp. 798-802
-
-
Ishitani, T.1
Ninomiya-Tsuji, J.2
Nagai, S.3
Nishita, M.4
Meneghini, M.5
Barker, N.6
Waterman, M.7
Bowerman, B.8
Clevers, H.9
Shibuya, H.10
Matsumoto, K.11
-
62
-
-
68849097853
-
Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy
-
Wang, Y. Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy. Mol. Cancer Ther., 2009, 8, 2103-2109.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2103-2109
-
-
Wang, Y.1
-
63
-
-
34447131518
-
The Wnt5A/PKC pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of EMT
-
Dissanayake, S. K.; Wade, M.; Johnson, C. E.; O'Connell, M. P.; Leotlela, P. D.; French, A. D.; Shah, K. V.; Hewitt, K. J.; Rosenthal, D.T.; Indig, F. E.; Jiang, Y.; Nickoloff, B. J.; Taub, D. D.; Trent, J. M.; Moon, R. T.; Bittner, M.; Weeraratna, A. T. The Wnt5A/PKC pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of EMT. J. Biol. Chem., 2007, 282, 17259-17271.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17259-17271
-
-
Dissanayake, S.K.1
Wade, M.2
Johnson, C.E.3
O'Connell, M.P.4
Leotlela, P.D.5
French, A.D.6
Shah, K.V.7
Hewitt, K.J.8
Rosenthal, D.T.9
Indig, F.E.10
Jiang, Y.11
Nickoloff, B.J.12
Taub, D.D.13
Trent, J.M.14
Moon, R.T.15
Bittner, M.16
Weeraratna, A.T.17
-
64
-
-
0037229938
-
Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
-
Jr., Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Dev. Biol., 2003, 253, 1-17.
-
(2003)
Dev. Biol.
, vol.253
, pp. 1-17
-
-
-
65
-
-
18844438774
-
Formin proteins: A domain-based approach
-
Higgs, H. N. Formin proteins: a domain-based approach. Trends Biochem. Sci., 2005, 30, 342-353.
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 342-353
-
-
Higgs, H.N.1
-
66
-
-
77951053765
-
Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis
-
Ju, R.; Cirone, P.; Lin, S.; Griesbach, H.; Slusarski, D. C.; Crews, C. M. Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc. Natl. Acad. Sci. USA, 2010, 107, 6906-6911.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 6906-6911
-
-
Ju, R.1
Cirone, P.2
Lin, S.3
Griesbach, H.4
Slusarski, D.C.5
Crews, C.M.6
-
67
-
-
0031456672
-
Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
-
Slusarski, D. C.; Corces, V. G.; Moon, R. T. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature, 1997, 390, 410-413.
-
(1997)
Nature
, vol.390
, pp. 410-413
-
-
Slusarski, D.C.1
Corces, V.G.2
Moon, R.T.3
-
68
-
-
33845666522
-
TGF-β activated kinase-1: New insights into the diverse roles of TAK1 in development and immunity
-
Delaney, J. R.; Mlodzik, M. TGF-β activated kinase-1: new insights into the diverse roles of TAK1 in development and immunity. Cell Cycle, 2006, 5, 2852-2855.
-
(2006)
Cell Cycle
, vol.5
, pp. 2852-2855
-
-
Delaney, J.R.1
Mlodzik, M.2
-
69
-
-
34248570795
-
Ubiquitin-mediated activation of TAK1 and IKK
-
Adhikari, A.; Xu, M.; Chen, Z. J. Ubiquitin-mediated activation of TAK1 and IKK. Oncogene, 2007, 26, 3214-3226.
-
(2007)
Oncogene
, vol.26
, pp. 3214-3226
-
-
Adhikari, A.1
Xu, M.2
Chen, Z.J.3
-
70
-
-
65349096856
-
TGF-β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells
-
Thakur, N.; Sorrentino, A.; Heldin, C. H.; Landström, M. TGF-β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells. Future Oncol., 2009, 5, 1-3.
-
(2009)
Future Oncol
, vol.5
, pp. 1-3
-
-
Thakur, N.1
Sorrentino, A.2
Heldin, C.H.3
Landström, M.4
-
71
-
-
77649273214
-
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex
-
Ishitani, T.; Hirao, T.; Suzuki, M.; Isoda, M.; Ishitani, S.; Harigaya, K.; Kitagawa, M.; Matsumoto, K.; Itoh, M. Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex. Nat. Cell Biol., 2010, 12, 278-285.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 278-285
-
-
Ishitani, T.1
Hirao, T.2
Suzuki, M.3
Isoda, M.4
Ishitani, S.5
Harigaya, K.6
Kitagawa, M.7
Matsumoto, K.8
Itoh, M.9
-
72
-
-
35748960839
-
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-β transactivation
-
Takada, I.; Mihara, M.; Suzawa, M.; Ohtake, F.; Kobayashi, S.; Igarashi, M.; Kato, S. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-β transactivation. Nat. Cell Biol., 2007, 9, 1273-1285.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1273-1285
-
-
Takada, I.1
Mihara, M.2
Suzawa, M.3
Ohtake, F.4
Kobayashi, S.5
Igarashi, M.6
Kato, S.7
-
73
-
-
40249109853
-
The IβB kinase: A bridge between inflammation and cancer
-
Karin, M. The IβB kinase: a bridge between inflammation and cancer. Cell Res., 2008, 18, 334-342.
-
(2008)
Cell Res
, vol.18
, pp. 334-342
-
-
Karin, M.1
-
74
-
-
0027395703
-
MMTV infection accelerates mammary carcinogenesis in Wnt1 transgenic mice by insertional activation of Fgf3 and Fgf4
-
Shackleford, G. M.; MacArthur, C. A.; Kwan, H. C.; Varmus, H. E. MMTV infection accelerates mammary carcinogenesis in Wnt1 transgenic mice by insertional activation of Fgf3 and Fgf4. Proc. Natl. Acad. Sci. USA, 1993, 90, 740-744.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 740-744
-
-
Shackleford, G.M.1
Macarthur, C.A.2
Kwan, H.C.3
Varmus, H.E.4
-
75
-
-
0028911173
-
Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of Fgf3 transgenic mice
-
Lee, F. S.; Lane, T. F.; Kuo, A.; Shackleford, G. M.; Leder, P. Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of Fgf3 transgenic mice. Proc. Natl. Acad. Sci. USA, 1995, 92, 2268-2272.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2268-2272
-
-
Lee, F.S.1
Lane, T.F.2
Kuo, A.3
Shackleford, G.M.4
Leder, P.5
-
76
-
-
50849124804
-
Common integration sites for MMTV in viral induced mouse mammary tumors
-
Callahan, R.; Smith, G. H. Common integration sites for MMTV in viral induced mouse mammary tumors. J. Mammary Gland Biol. Neoplasia, 2008, 13, 309-321.
-
(2008)
J. Mammary Gland Biol. Neoplasia
, vol.13
, pp. 309-321
-
-
Callahan, R.1
Smith, G.H.2
-
77
-
-
0141919600
-
Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/TCF complex
-
Shimokawa, T.; Furukawa, Y.; Sakai, M.; Li, M.; Miwa, N.; Lin, Y. M.; Nakamura, Y. Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/TCF complex. Cancer Res., 2003, 63, 6116-6120.
-
(2003)
Cancer Res
, vol.63
, pp. 6116-6120
-
-
Shimokawa, T.1
Furukawa, Y.2
Sakai, M.3
Li, M.4
Miwa, N.5
Lin, Y.M.6
Nakamura, Y.7
-
78
-
-
48549092215
-
Inhibition of FGF19 reduces tumor growth by modulating β- catenin signaling
-
Pai, R.; Dunlap, D.; Qing, J.; Mohtashemi, I.; Hotzel, K.; French, D. M. Inhibition of FGF19 reduces tumor growth by modulating β- catenin signaling. Cancer Res., 2008, 68, 5086-5095.
-
(2008)
Cancer Res
, vol.68
, pp. 5086-5095
-
-
Pai, R.1
Dunlap, D.2
Qing, J.3
Mohtashemi, I.4
Hotzel, K.5
French, D.M.6
-
79
-
-
77953732983
-
FGF receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the MMTV-Wnt1 mouse model of breast cancer
-
Pond, A. C.; Herschkowitz, J. I.; Schwertfeger, K. L.; Welm, B.; Zhang, Y.; York, B.; Cardiff, R. D.; Hilsenbeck, S.; Perou, C. M.; Creighton, C. J.; Lloyd, R. E.; Rosen, J. M. FGF receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the MMTV-Wnt1 mouse model of breast cancer. Cancer Res., 2010, 70, 4868-4679.
-
(2010)
Cancer Res
, vol.70
, pp. 4868-4679
-
-
Pond, A.C.1
Herschkowitz, J.I.2
Schwertfeger, K.L.3
Welm, B.4
Zhang, Y.5
York, B.6
Cardiff, R.D.7
Hilsenbeck, S.8
Perou, C.M.9
Creighton, C.J.10
Lloyd, R.E.11
Rosen, J.M.12
-
80
-
-
61449231683
-
Effects of age and gender on WNT gene expression in human bone marrow stromal cells
-
Shen, L.; Zhou, S.; Glowacki, J. Effects of age and gender on WNT gene expression in human bone marrow stromal cells. J. Cell. Biochem., 2009, 106, 337-343.
-
(2009)
J. Cell. Biochem.
, vol.106
, pp. 337-343
-
-
Shen, L.1
Zhou, S.2
Glowacki, J.3
-
81
-
-
77956557074
-
Expression profile of the embryonic markers Nanog, Oct-4, SSEA-1, SSEA-4 and FRIZZLED-9 receptor in human periodontal ligament mesenchymal stem cells
-
Trubiani, O.; Zalzal, S. F.; Paganelli, R.; Marchisio, M.; Giancola, R.; Pizzicannella, J.; Bühring, H. J.; Piattelli, M.; Caputi, S.; Nanci, A. Expression profile of the embryonic markers Nanog, Oct-4, SSEA-1, SSEA-4 and FRIZZLED-9 receptor in human periodontal ligament mesenchymal stem cells. J. Cell. Physiol., 2010, 225(1), 123-131.
-
(2010)
J. Cell. Physiol.
, vol.225
, Issue.1
, pp. 123-131
-
-
Trubiani, O.1
Zalzal, S.F.2
Paganelli, R.3
Marchisio, M.4
Giancola, R.5
Pizzicannella, J.6
Bühring, H.J.7
Piattelli, M.8
Caputi, S.9
Nanci, A.10
-
82
-
-
77953851809
-
The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development
-
Maruyama, T.; Mirando, A. J.; Deng, C. X.; Hsu, W. The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development. Sci Signal., 2010, 3, ra40.
-
(2010)
Sci Signal
, vol.3
-
-
Maruyama, T.1
Mirando, A.J.2
Deng, C.X.3
Hsu, W.4
-
83
-
-
0034637103
-
Inhibition of adipogenesis by Wnt signaling
-
Ross, S. E.; Hemati, N.; Longo, K. A.; Bennett, C. N.; Lucas, P. C.; Erickson, R. L.; MacDougald, O. A. Inhibition of adipogenesis by Wnt signaling. Science, 2000, 289, 950-953.
-
(2000)
Science
, vol.289
, pp. 950-953
-
-
Ross, S.E.1
Hemati, N.2
Longo, K.A.3
Bennett, C.N.4
Lucas, P.C.5
Erickson, R.L.6
Macdougald, O.A.7
-
84
-
-
77951519413
-
Activation of canonical Wnt signaling in mature adipocytes increases β-catenin levels and leads to cell dedifferentiation and insulin resistance
-
Gustafson, B.; Smith, U. Activation of canonical Wnt signaling in mature adipocytes increases β-catenin levels and leads to cell dedifferentiation and insulin resistance. J. Biol. Chem., 2010, 285, 14031-14041.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 14031-14041
-
-
Gustafson, B.1
Smith, U.2
-
85
-
-
40949128686
-
Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways
-
Raucci, A.; Bellosta, P.; Grassi, R.; Basilico, C.; Mansukhani, A. Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways. J. Cell. Physiol., 2008, 215, 442-451.
-
(2008)
J. Cell. Physiol.
, vol.215
, pp. 442-451
-
-
Raucci, A.1
Bellosta, P.2
Grassi, R.3
Basilico, C.4
Mansukhani, A.5
-
86
-
-
2342542418
-
Roles of Fgf10 in adipogenesis in vivo
-
Asaki, T.; Konishi, M.; Miyake, A.; Kato, S.; Tomizawa, M.; Itoh, N. Roles of Fgf10 in adipogenesis in vivo. Mol. Cell. Endocrinol., 2004, 218, 119-128.
-
(2004)
Mol. Cell. Endocrinol
, vol.218
, pp. 119-128
-
-
Asaki, T.1
Konishi, M.2
Miyake, A.3
Kato, S.4
Tomizawa, M.5
Itoh, N.6
-
87
-
-
0036225314
-
Dapper, a Dishevelled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation
-
Cheyette, B. N.; Waxman, J. S.; Miller, J. R.; Takemaru, K.; Sheldahl, L. C.; Khlebtsova, N.; Fox, E. P.; Earnest, T.; Moon, R. T. Dapper, a Dishevelled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation. Dev. Cell, 2002, 2, 449-461.
-
(2002)
Dev. Cell
, vol.2
, pp. 449-461
-
-
Cheyette, B.N.1
Waxman, J.S.2
Miller, J.R.3
Takemaru, K.4
Sheldahl, L.C.5
Khlebtsova, N.6
Fox, E.P.7
Earnest, T.8
Moon, R.T.9
-
88
-
-
0642348017
-
Identification and characterization of human DAPPER1 and DAPPER2 genes in silico
-
Katoh, M.; Katoh, M. Identification and characterization of human DAPPER1 and DAPPER2 genes in silico. Int. J. Oncol., 2003, 22, 907-913.
-
(2003)
Int. J. Oncol.
, vol.22
, pp. 907-913
-
-
Katoh, M.1
Katoh, M.2
-
89
-
-
33750982724
-
Dact1 presomitic mesoderm expression oscillates in phase with Axin2 in the somitogenesis clock of mice
-
Suriben, R.; Fisher, D. A.; Cheyette, B. N. Dact1 presomitic mesoderm expression oscillates in phase with Axin2 in the somitogenesis clock of mice. Dev. Dyn., 2006, 235, 3177-3183.
-
(2006)
Dev. Dyn
, vol.235
, pp. 3177-3183
-
-
Suriben, R.1
Fisher, D.A.2
Cheyette, B.N.3
-
90
-
-
33845892748
-
Jag1 is a β-catenin target gene required for ectopic hair follicle formation in adult epidermis
-
Estrach, S.; Ambler, C. A.; Lo Celso, C.; Hozumi, K.; Watt, F. M. Jag1 is a β-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development, 2006, 133, 4427-4438.
-
(2006)
Development
, vol.133
, pp. 4427-4438
-
-
Estrach, S.1
Ambler, C.A.2
Lo Celso, C.3
Hozumi, K.4
Watt, F.M.5
-
91
-
-
57449090247
-
Control of early fate decisions in human ES cells by distinct states of TGFβ pathway activity
-
Greber, B.; Lehrach, H.; Adjaye, J. Control of early fate decisions in human ES cells by distinct states of TGFβ pathway activity. Stem Cells Dev., 2008, 17, 1065-1077.
-
(2008)
Stem Cells Dev
, vol.17
, pp. 1065-1077
-
-
Greber, B.1
Lehrach, H.2
Adjaye, J.3
-
92
-
-
36549025433
-
Wnt5a is required for proper mammary gland development and TGFβ-mediated inhibition of ductal growth
-
Roarty, K.; Serra, R. Wnt5a is required for proper mammary gland development and TGFβ-mediated inhibition of ductal growth. Development, 2007, 134, 3929-3939.
-
(2007)
Development
, vol.134
, pp. 3929-3939
-
-
Roarty, K.1
Serra, R.2
-
93
-
-
2442622480
-
Ihh gene is a target of the BMP signaling pathway
-
Seki, K.; Hata, A. Ihh gene is a target of the BMP signaling pathway. J. Biol. Chem., 2004, 279, 18544-18549.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18544-18549
-
-
Seki, K.1
Hata, A.2
-
94
-
-
0037085379
-
Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation
-
Yoon, J. W.; Kita, Y.; Frank, D. J.; Majewski, R. R.; Konicek, B. A.; Nobrega, M. A.; Jacob, H.; Walterhouse, D.; Iannaccone, P. Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation. J. Biol. Chem., 2002, 277, 5548-5555.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5548-5555
-
-
Yoon, J.W.1
Kita, Y.2
Frank, D.J.3
Majewski, R.R.4
Konicek, B.A.5
Nobrega, M.A.6
Jacob, H.7
Walterhouse, D.8
Iannaccone, P.9
-
95
-
-
33746951471
-
Selective modulation of Hedgehog/GLI target gene expression by EGF signaling in human keratinocytes
-
Kasper, M.; Schnidar, H.; Neill, G. W.; Hanneder, M.; Klingler, S.; Blaas, L.; Schmid, C.; Hauser-Kronberger, C.; Regl, G.; Philpott, M. P.; Aberger, F. Selective modulation of Hedgehog/GLI target gene expression by EGF signaling in human keratinocytes. Mol. Cell. Biol., 2006, 26, 6283-6298.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6283-6298
-
-
Kasper, M.1
Schnidar, H.2
Neill, G.W.3
Hanneder, M.4
Klingler, S.5
Blaas, L.6
Schmid, C.7
Hauser-Kronberger, C.8
Regl, G.9
Philpott, M.P.10
Aberger, F.11
-
96
-
-
30344439849
-
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity
-
Hallikas, O.; Palin, K.; Sinjushina, N.; Rautiainen, R.; Partanen, J.; Ukkonen, E.; Taipale, J. Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell, 2006, 124, 47-59.
-
(2006)
Cell
, vol.124
, pp. 47-59
-
-
Hallikas, O.1
Palin, K.2
Sinjushina, N.3
Rautiainen, R.4
Partanen, J.5
Ukkonen, E.6
Taipale, J.7
-
97
-
-
33644878320
-
WNT antagonist, SFRP1, is Hedgehog signaling target
-
Katoh, Y.; Katoh, M. WNT antagonist, SFRP1, is Hedgehog signaling target. Int. J. Mol. Med., 2006, 17, 171-175.
-
(2006)
Int. J. Mol. Med.
, vol.17
, pp. 171-175
-
-
Katoh, Y.1
Katoh, M.2
-
98
-
-
70350534843
-
Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Katoh, Y.; Katoh, M. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr. Mol. Med., 2009, 9, 873-886.
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
99
-
-
10744233571
-
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
-
van den Brink, G. R.; Bleuming, S. A.; Hardwick, J. C.; Schepman, B. L.; Offerhaus, G. J.; Keller, J. J.; Nielsen, C.; Gaffield, W.; van Deventer, S. J.; Roberts, D. J.; Peppelenbosch, M. P. Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. Nat. Genet., 2004, 36, 277-282.
-
(2004)
Nat. Genet
, vol.36
, pp. 277-282
-
-
van den Brink, G.R.1
Bleuming, S.A.2
Hardwick, J.C.3
Schepman, B.L.4
Offerhaus, G.J.5
Keller, J.J.6
Nielsen, C.7
Gaffield, W.8
van Deventer, S.J.9
Roberts, D.J.10
Peppelenbosch, M.P.11
-
100
-
-
40949137792
-
Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGFβ-mediated activation of the ALK5-Smad3 pathway
-
Yoo, Y. A.; Kang, M. H.; Kim, J. S.; Oh, S. C. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGFβ-mediated activation of the ALK5-Smad3 pathway. Carcinogenesis, 2008, 29, 480-490.
-
(2008)
Carcinogenesis
, vol.29
, pp. 480-490
-
-
Yoo, Y.A.1
Kang, M.H.2
Kim, J.S.3
Oh, S.C.4
-
101
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
G. R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA, 1981, 78, 7634-7638.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 7634-7638
-
-
-
102
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J. A.; Itskovitz-Eldor, J.; Shapiro, S. S.; Waknitz, M. A.; Swiergiel, J. J.; Marshall, V. S.; Jones, J. M. Embryonic stem cell lines derived from human blastocysts. Science, 1998, 282, 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
103
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
Tesar, P. J.; Chenoweth, J. G.; Brook, F. A.; Davies, T. J.; Evans, E. P.; Mack, D. L.; Gardner, R. L.; McKay, R. D. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 2007, 448, 196-199.
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
Gardner, R.L.7
McKay, R.D.8
-
104
-
-
48749109823
-
Pluripotent stem cell lines
-
Yu, J.; Thomson, J. A. Pluripotent stem cell lines. Genes Dev., 2008, 22, 1987-1997.
-
(2008)
Genes Dev
, vol.22
, pp. 1987-1997
-
-
Yu, J.1
Thomson, J.A.2
-
105
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K.; Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 2006, 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
106
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park, I. H.; Zhao, R.; West, J. A.; Yabuuchi, A.; Huo, H.; Ince, T. A.; Lerou, P. H.; Lensch, M. W.; Daley, G. Q. Reprogramming of human somatic cells to pluripotency with defined factors. Nature, 2008, 451, 141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
Lerou, P.H.7
Lensch, M.W.8
Daley, G.Q.9
-
107
-
-
67649222358
-
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
-
Chin, M. H.; Mason, M. J.; Xie, W.; Volinia, S.; Singer, M.; Peterson, C.; Ambartsumyan, G.; Aimiuwu, O.; Richter, L.; Zhang, J.; Khvorostov, I.; Ott, V.; Grunstein, M.; Lavon, N.; Benvenisty, N.; Croce, C. M.; Clark, A. T.; Baxter, T.; Pyle, A. D.; Teitell, M. A.; Pelegrini, M.; Plath, K.; Lowry, W. E. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell, 2009, 5, 111-123.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 111-123
-
-
Chin, M.H.1
Mason, M.J.2
Xie, W.3
Volinia, S.4
Singer, M.5
Peterson, C.6
Ambartsumyan, G.7
Aimiuwu, O.8
Richter, L.9
Zhang, J.10
Khvorostov, I.11
Ott, V.12
Grunstein, M.13
Lavon, N.14
Benvenisty, N.15
Croce, C.M.16
Clark, A.T.17
Baxter, T.18
Pyle, A.D.19
Teitell, M.A.20
Pelegrini, M.21
Plath, K.22
Lowry, W.E.23
more..
-
108
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng, B.; Ng, J. H.; Heng, J. C.; Ng, H. H. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell, 2009, 4, 301-312.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng, J.H.2
Heng, J.C.3
Ng, H.H.4
-
109
-
-
48149107133
-
Wnt signaling promotes reprogramming of somatic cells to pluripotency
-
Marson, A.; Foreman, R.; Chevalier, B.; Bilodeau, S.; Kahn, M.; Young, R. A.; Jaenisch, R. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell, 2008, 3, 132-135.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 132-135
-
-
Marson, A.1
Foreman, R.2
Chevalier, B.3
Bilodeau, S.4
Kahn, M.5
Young, R.A.6
Jaenisch, R.7
-
110
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui, K.; Tokuzawa, Y.; Itoh, H.; Segawa, K.; Murakami, M.; Takahashi, K.; Maruyama, M.; Maeda, M.; Yamanaka, S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell, 2003, 113, 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
111
-
-
41149174852
-
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
-
Cole, M. F.; Johnstone, S. E.; Newman, J. J.; Kagey, M. H.; Young, R. A. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev., 2008, 22, 746-755.
-
(2008)
Genes Dev
, vol.22
, pp. 746-755
-
-
Cole, M.F.1
Johnstone, S.E.2
Newman, J.J.3
Kagey, M.H.4
Young, R.A.5
-
112
-
-
58049192815
-
Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors
-
Li, W.; Wei, W.; Zhu, S.; Zhu, J.; Shi, Y.; Lin, T.; Hao, E.; Hayek, A.; Deng, H.; Ding, S. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell, 2009, 4, 16-19.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 16-19
-
-
Li, W.1
Wei, W.2
Zhu, S.3
Zhu, J.4
Shi, Y.5
Lin, T.6
Hao, E.7
Hayek, A.8
Deng, H.9
Ding, S.10
-
113
-
-
52449116723
-
WNT signaling in stem cell biology and regenerative medicine
-
M. WNT signaling in stem cell biology and regenerative medicine. Curr. Drug Targets, 2008, 9, 565-570.
-
(2008)
Curr. Drug Targets
, vol.9
, pp. 565-570
-
-
-
114
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet, D.; Dick, J. E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med., 1997, 3, 730-737.
-
(1997)
Nat. Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
115
-
-
77953720558
-
Cancer stem cells and self-renewal
-
O'Brien, C. A.; Kreso, A.; Jamieson, C. H. Cancer stem cells and self-renewal. Clin. Cancer Res., 2010, 16, 3113-3120.
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 3113-3120
-
-
O'Brien, C.A.1
Kreso, A.2
Jamieson, C.H.3
-
116
-
-
42449146614
-
Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change, and genetic alteration in gastric cancer
-
M. Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change, and genetic alteration in gastric cancer. Cancer Biol. Ther., 2007, 6, 832-839.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 832-839
-
-
-
117
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann, P. C.; Huber, S. L.; Herrler, T.; Aicher, A.; Ellwart, J.W.; Guba, M.; Bruns, C. J.; Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell, 2007, 1, 313-323.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
118
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman, D. M.; Karhadkar, S. S.; Maitra, A.; Montes De Oca, R.; Gerstenblith, M. R.; Briggs, K.; Parker, A. R.; Shimada, Y.; Eshleman, J. R.; Watkins, D.N.; Beachy, P. A. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature, 2003, 425, 846-851.
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
119
-
-
75449087368
-
Integrative genomic analyses of CXCR4: Transcriptional regulation of CXCR4 based on TGFβ, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors
-
Katoh, M.; Katoh, M. Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFβ, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. Int. J. Oncol., 2010, 36, 415-20.
-
(2010)
Int. J. Oncol.
, vol.36
, pp. 415-420
-
-
Katoh, M.1
Katoh, M.2
-
120
-
-
53049097596
-
Hedgehog signaling, epithelial-tomesenchymal transition, and miRNA
-
Katoh, Y.; Katoh, M. Hedgehog signaling, epithelial-tomesenchymal transition, and miRNA. Int. J. Mol. Med., 2008, 22, 271-275.
-
(2008)
Int. J. Mol. Med.
, vol.22
, pp. 271-275
-
-
Katoh, Y.1
Katoh, M.2
|