Transcriptional down-regulation of the Wnt antagonist SFRP1 in haematopoietic cells of patients with different risk types of MDS

Leukemia Research

Volumn 34, Issue 12, 2010, Pages 1610-1616

  Reins, Jana ^a   Mossner, Maximilian ^a   Neumann, Martin ^a   Platzbecker, Uwe ^b   Schumann, Christiane ^c   Thiel, Eckhard ^a   Hofmann, Wolf Karsten ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Acute leukaemia; MDS; Promoter methylation; Pyrosequencing; SFRP; Wnt signalling

Indexed keywords

FRIZZLED PROTEIN; FRIZZLED PROTEIN 3; MESSENGER RNA; SECRETED FRIZZLED RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; DOWN REGULATION; GENE MUTATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ACUTE DISEASE; CHRONIC DISEASE; DNA METHYLATION; DOWN-REGULATION; FEMALE; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LEUKEMIA, MYELOID, ACUTE; MALE; MEMBRANE PROTEINS; MYELODYSPLASTIC SYNDROMES; PROMOTER REGIONS, GENETIC; RECEPTORS, G-PROTEIN-COUPLED; RISK FACTORS; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 78149357406     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.04.013     Document Type: Article

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