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Volumn 5, Issue 1, 2009, Pages 1-3

TGF-β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE LKB1; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE;

EID: 65349096856     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/14796694.5.1.1     Document Type: Editorial
Times cited : (20)

References (27)
  • 1
    • 47549090432 scopus 로고    scopus 로고
    • TGFβ in cancer
    • Massagué J: TGFβ in cancer. Cell 134(2), 215-230 (2008).
    • (2008) Cell , vol.134 , Issue.2 , pp. 215-230
    • Massagué, J.1
  • 2
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, ten Dijke P: TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390(6659), 465-471 (1997).
    • (1997) Nature , vol.390 , Issue.6659 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    ten Dijke, P.3
  • 3
    • 53349164136 scopus 로고    scopus 로고
    • The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
    • Sorrentino A, Thakur N, Grimsby S et al.: The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat. Cell Biol. 10(10), 1199-1207 (2008).
    • (2008) Nat. Cell Biol , vol.10 , Issue.10 , pp. 1199-1207
    • Sorrentino, A.1    Thakur, N.2    Grimsby, S.3
  • 4
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • Thiery JP: Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 15 (6), 740-746 (2003).
    • (2003) Curr. Opin. Cell Biol , vol.15 , Issue.6 , pp. 740-746
    • Thiery, J.P.1
  • 5
    • 22144461325 scopus 로고    scopus 로고
    • Transforming growth factor-β signaling during epithelial-mesenchymal transformation: Implications for embryogenesis and tumor metastasis
    • Nawshad A, Lagamba D, Polad A, Hay ED: Transforming growth factor-β signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 179(1-2), 11-23 (2005).
    • (2005) Cells Tissues Organs , vol.179 , Issue.1-2 , pp. 11-23
    • Nawshad, A.1    Lagamba, D.2    Polad, A.3    Hay, E.D.4
  • 6
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
    • Moustakas A, Heldin CH: Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 98(10), 1512-1520 (2007).
    • (2007) Cancer Sci , vol.98 , Issue.10 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.H.2
  • 7
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP: Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7(2), 131-142 (2006).
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 8
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
    • Yamaguchi K, Shirakabe K, Shibuya H et al.: Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270(5244), 2008-2011 (1995).
    • (1995) Science , vol.270 , Issue.5244 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3
  • 9
    • 34248570795 scopus 로고    scopus 로고
    • Ubiquitin-mediated activation-of TAK1 and IKK
    • Adhikari A, Xu M, Chen ZJ: Ubiquitin-mediated activation-of TAK1 and IKK. Oncogene 26(22), 3214-3226 (2007).
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3214-3226
    • Adhikari, A.1    Xu, M.2    Chen, Z.J.3
  • 10
    • 33748747706 scopus 로고    scopus 로고
    • Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
    • Momcilovic M, Hong SP, Carlson M: Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J. Biol. Chem. 281(35), 25336-25343 (2006).
    • (2006) J. Biol. Chem , vol.281 , Issue.35 , pp. 25336-25343
    • Momcilovic, M.1    Hong, S.P.2    Carlson, M.3
  • 11
    • 33751229931 scopus 로고    scopus 로고
    • A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
    • Xie M, Zhang D, Dyck JR et al.: A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc. Natl Acad. Sci. USA 103(46), 17378-17383 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.46 , pp. 17378-17383
    • Xie, M.1    Zhang, D.2    Dyck, J.R.3
  • 12
    • 50049105823 scopus 로고    scopus 로고
    • The regulation of AMP-activated protein kinase by upstream kinases
    • Carling D, Sanders MJ, Woods A: The regulation of AMP-activated protein kinase by upstream kinases. Int. J. Obes. Lond. 32(Suppl. 4), S55-S59 (2008).
    • (2008) Int. J. Obes. Lond , vol.32 , Issue.SUPPL. 4
    • Carling, D.1    Sanders, M.J.2    Woods, A.3
  • 13
    • 0035913278 scopus 로고    scopus 로고
    • TAK1 is a ubiquitin-dependent kinase of MKK and IKK
    • Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ: TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412(6844), 346-351 (2001).
    • (2001) Nature , vol.412 , Issue.6844 , pp. 346-351
    • Wang, C.1    Deng, L.2    Hong, M.3    Akkaraju, G.R.4    Inoue, J.5    Chen, Z.J.6
  • 14
    • 4344712350 scopus 로고    scopus 로고
    • TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
    • Kanayama A, Seth RB, Sun L et al.: TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains. Mol. Cell 15(4), 535-548 (2004).
    • (2004) Mol. Cell , vol.15 , Issue.4 , pp. 535-548
    • Kanayama, A.1    Seth, R.B.2    Sun, L.3
  • 15
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng L, Wang C, Spencer E et al.: Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103(2), 351-361 (2000).
    • (2000) Cell , vol.103 , Issue.2 , pp. 351-361
    • Deng, L.1    Wang, C.2    Spencer, E.3
  • 16
    • 39149139338 scopus 로고    scopus 로고
    • TGF-β signalling-related markers in cancer patients with bone metastasis
    • Baselga J, Rothenberg ML, Tabernero J et al.: TGF-β signalling-related markers in cancer patients with bone metastasis. Biomarkers 13(2), 217-236 (2008).
    • (2008) Biomarkers , vol.13 , Issue.2 , pp. 217-236
    • Baselga, J.1    Rothenberg, M.L.2    Tabernero, J.3
  • 17
    • 44649098788 scopus 로고    scopus 로고
    • Androgen receptor signalling in prostate: Effects of stromal factors on normal and cancer stem cells
    • Berry PA, Maitland NJ, Collins AT: Androgen receptor signalling in prostate: effects of stromal factors on normal and cancer stem cells. Mol. Cell. Endocrinol. 288(1-2), 30-37 (2008).
    • (2008) Mol. Cell. Endocrinol , vol.288 , Issue.1-2 , pp. 30-37
    • Berry, P.A.1    Maitland, N.J.2    Collins, A.T.3
  • 18
    • 47149102561 scopus 로고    scopus 로고
    • Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
    • Birnie R, Bryce SD, Roome C et al.: Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biol. 9(5), R83 (2008).
    • (2008) Genome Biol , vol.9 , Issue.5
    • Birnie, R.1    Bryce, S.D.2    Roome, C.3
  • 19
    • 58249122148 scopus 로고    scopus 로고
    • Androgen receptor and growth factor signaling partnerships in prostate cancer cells
    • Zhu ML, Kyprianou N: Androgen receptor and growth factor signaling partnerships in prostate cancer cells. Endocr. Relat. Cancer 15(4), 841-849 (2008).
    • (2008) Endocr. Relat. Cancer , vol.15 , Issue.4 , pp. 841-849
    • Zhu, M.L.1    Kyprianou, N.2
  • 20
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin M: Nuclear factor-κB in cancer development and progression Nature 441(7092), 431-436 (2006).
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 21
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signalling
    • Derynck R, Zhang YE: Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425(6958), 577-584 (2003).
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 22
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-β signals
    • Moustakas A, Heldin CH: Non-Smad TGF-β signals. J. Cell Sci. 118(Pt 16), 3573-3584 (2005).
    • (2005) J. Cell Sci , vol.118 , Issue.PART 16 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 23
    • 33750352214 scopus 로고    scopus 로고
    • Results of G004, a Phase IIb study in recurrent glioblastoma patients with the TGF-β2 targeted compound AP 12009
    • Abstract 1553
    • Bogdahn U, Oliushine VE, Parfenov VE et al.: Results of G004, a Phase IIb study in recurrent glioblastoma patients with the TGF-β2 targeted compound AP 12009. J. Clin. Oncol., 2006 ASCO Annual Meeting Proceedings 24(18S) (2006) (Abstract 1553).
    • (2006) J. Clin. Oncol., 2006 ASCO Annual Meeting Proceedings , vol.24 , Issue.18 S
    • Bogdahn, U.1    Oliushine, V.E.2    Parfenov, V.E.3
  • 24
    • 48449086316 scopus 로고    scopus 로고
    • TGF-β: A master of all T cell trades
    • Li MO, Flavell RA: TGF-β: a master of all T cell trades. Cell 134(3), 392-404 (2008).
    • (2008) Cell , vol.134 , Issue.3 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 25
    • 58149250280 scopus 로고    scopus 로고
    • Review of the activation of TGF-β in immunity
    • Taylor AW. Review of the activation of TGF-β in immunity. J. Leukoc. Biol. 85(1), 29-33 (2008).
    • (2008) J. Leukoc. Biol , vol.85 , Issue.1 , pp. 29-33
    • Taylor, A.W.1
  • 26
    • 39149107801 scopus 로고    scopus 로고
    • Understanding the role of transforming growth factor-β signalling in the heart: Overview of studies using genetic mouse models
    • Xiao H, Zhang YY. Understanding the role of transforming growth factor-β signalling in the heart: overview of studies using genetic mouse models. Clin. Exp. Pharmacol. Physiol. 35(3), 335-341 (2008).
    • (2008) Clin. Exp. Pharmacol. Physiol , vol.35 , Issue.3 , pp. 335-341
    • Xiao, H.1    Zhang, Y.Y.2
  • 27
    • 34548832771 scopus 로고    scopus 로고
    • Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers
    • Liu W, Chang BL, Cramer S et al.: Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers. Clin. Cancer Res. 13(17), 5028-5033 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.17 , pp. 5028-5033
    • Liu, W.1    Chang, B.L.2    Cramer, S.3


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