-
1
-
-
47549090432
-
TGFβ in cancer
-
Massagué J: TGFβ in cancer. Cell 134(2), 215-230 (2008).
-
(2008)
Cell
, vol.134
, Issue.2
, pp. 215-230
-
-
Massagué, J.1
-
2
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, ten Dijke P: TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390(6659), 465-471 (1997).
-
(1997)
Nature
, vol.390
, Issue.6659
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
ten Dijke, P.3
-
3
-
-
53349164136
-
The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
-
Sorrentino A, Thakur N, Grimsby S et al.: The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat. Cell Biol. 10(10), 1199-1207 (2008).
-
(2008)
Nat. Cell Biol
, vol.10
, Issue.10
, pp. 1199-1207
-
-
Sorrentino, A.1
Thakur, N.2
Grimsby, S.3
-
4
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery JP: Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 15 (6), 740-746 (2003).
-
(2003)
Curr. Opin. Cell Biol
, vol.15
, Issue.6
, pp. 740-746
-
-
Thiery, J.P.1
-
5
-
-
22144461325
-
Transforming growth factor-β signaling during epithelial-mesenchymal transformation: Implications for embryogenesis and tumor metastasis
-
Nawshad A, Lagamba D, Polad A, Hay ED: Transforming growth factor-β signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 179(1-2), 11-23 (2005).
-
(2005)
Cells Tissues Organs
, vol.179
, Issue.1-2
, pp. 11-23
-
-
Nawshad, A.1
Lagamba, D.2
Polad, A.3
Hay, E.D.4
-
6
-
-
34548175512
-
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
-
Moustakas A, Heldin CH: Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 98(10), 1512-1520 (2007).
-
(2007)
Cancer Sci
, vol.98
, Issue.10
, pp. 1512-1520
-
-
Moustakas, A.1
Heldin, C.H.2
-
7
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
Thiery JP, Sleeman JP: Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7(2), 131-142 (2006).
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, Issue.2
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
8
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H et al.: Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270(5244), 2008-2011 (1995).
-
(1995)
Science
, vol.270
, Issue.5244
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
-
9
-
-
34248570795
-
Ubiquitin-mediated activation-of TAK1 and IKK
-
Adhikari A, Xu M, Chen ZJ: Ubiquitin-mediated activation-of TAK1 and IKK. Oncogene 26(22), 3214-3226 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3214-3226
-
-
Adhikari, A.1
Xu, M.2
Chen, Z.J.3
-
10
-
-
33748747706
-
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
-
Momcilovic M, Hong SP, Carlson M: Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J. Biol. Chem. 281(35), 25336-25343 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.35
, pp. 25336-25343
-
-
Momcilovic, M.1
Hong, S.P.2
Carlson, M.3
-
11
-
-
33751229931
-
A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
-
Xie M, Zhang D, Dyck JR et al.: A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc. Natl Acad. Sci. USA 103(46), 17378-17383 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.46
, pp. 17378-17383
-
-
Xie, M.1
Zhang, D.2
Dyck, J.R.3
-
12
-
-
50049105823
-
The regulation of AMP-activated protein kinase by upstream kinases
-
Carling D, Sanders MJ, Woods A: The regulation of AMP-activated protein kinase by upstream kinases. Int. J. Obes. Lond. 32(Suppl. 4), S55-S59 (2008).
-
(2008)
Int. J. Obes. Lond
, vol.32
, Issue.SUPPL. 4
-
-
Carling, D.1
Sanders, M.J.2
Woods, A.3
-
13
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ: TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412(6844), 346-351 (2001).
-
(2001)
Nature
, vol.412
, Issue.6844
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
14
-
-
4344712350
-
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
-
Kanayama A, Seth RB, Sun L et al.: TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains. Mol. Cell 15(4), 535-548 (2004).
-
(2004)
Mol. Cell
, vol.15
, Issue.4
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
-
15
-
-
0034644474
-
Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L, Wang C, Spencer E et al.: Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103(2), 351-361 (2000).
-
(2000)
Cell
, vol.103
, Issue.2
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
-
16
-
-
39149139338
-
TGF-β signalling-related markers in cancer patients with bone metastasis
-
Baselga J, Rothenberg ML, Tabernero J et al.: TGF-β signalling-related markers in cancer patients with bone metastasis. Biomarkers 13(2), 217-236 (2008).
-
(2008)
Biomarkers
, vol.13
, Issue.2
, pp. 217-236
-
-
Baselga, J.1
Rothenberg, M.L.2
Tabernero, J.3
-
17
-
-
44649098788
-
Androgen receptor signalling in prostate: Effects of stromal factors on normal and cancer stem cells
-
Berry PA, Maitland NJ, Collins AT: Androgen receptor signalling in prostate: effects of stromal factors on normal and cancer stem cells. Mol. Cell. Endocrinol. 288(1-2), 30-37 (2008).
-
(2008)
Mol. Cell. Endocrinol
, vol.288
, Issue.1-2
, pp. 30-37
-
-
Berry, P.A.1
Maitland, N.J.2
Collins, A.T.3
-
18
-
-
47149102561
-
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
-
Birnie R, Bryce SD, Roome C et al.: Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biol. 9(5), R83 (2008).
-
(2008)
Genome Biol
, vol.9
, Issue.5
-
-
Birnie, R.1
Bryce, S.D.2
Roome, C.3
-
19
-
-
58249122148
-
Androgen receptor and growth factor signaling partnerships in prostate cancer cells
-
Zhu ML, Kyprianou N: Androgen receptor and growth factor signaling partnerships in prostate cancer cells. Endocr. Relat. Cancer 15(4), 841-849 (2008).
-
(2008)
Endocr. Relat. Cancer
, vol.15
, Issue.4
, pp. 841-849
-
-
Zhu, M.L.1
Kyprianou, N.2
-
20
-
-
33745298519
-
Nuclear factor-κB in cancer development and progression
-
Karin M: Nuclear factor-κB in cancer development and progression Nature 441(7092), 431-436 (2006).
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
21
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
Derynck R, Zhang YE: Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425(6958), 577-584 (2003).
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
22
-
-
24944497786
-
Non-Smad TGF-β signals
-
Moustakas A, Heldin CH: Non-Smad TGF-β signals. J. Cell Sci. 118(Pt 16), 3573-3584 (2005).
-
(2005)
J. Cell Sci
, vol.118
, Issue.PART 16
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
23
-
-
33750352214
-
Results of G004, a Phase IIb study in recurrent glioblastoma patients with the TGF-β2 targeted compound AP 12009
-
Abstract 1553
-
Bogdahn U, Oliushine VE, Parfenov VE et al.: Results of G004, a Phase IIb study in recurrent glioblastoma patients with the TGF-β2 targeted compound AP 12009. J. Clin. Oncol., 2006 ASCO Annual Meeting Proceedings 24(18S) (2006) (Abstract 1553).
-
(2006)
J. Clin. Oncol., 2006 ASCO Annual Meeting Proceedings
, vol.24
, Issue.18 S
-
-
Bogdahn, U.1
Oliushine, V.E.2
Parfenov, V.E.3
-
24
-
-
48449086316
-
TGF-β: A master of all T cell trades
-
Li MO, Flavell RA: TGF-β: a master of all T cell trades. Cell 134(3), 392-404 (2008).
-
(2008)
Cell
, vol.134
, Issue.3
, pp. 392-404
-
-
Li, M.O.1
Flavell, R.A.2
-
25
-
-
58149250280
-
Review of the activation of TGF-β in immunity
-
Taylor AW. Review of the activation of TGF-β in immunity. J. Leukoc. Biol. 85(1), 29-33 (2008).
-
(2008)
J. Leukoc. Biol
, vol.85
, Issue.1
, pp. 29-33
-
-
Taylor, A.W.1
-
26
-
-
39149107801
-
Understanding the role of transforming growth factor-β signalling in the heart: Overview of studies using genetic mouse models
-
Xiao H, Zhang YY. Understanding the role of transforming growth factor-β signalling in the heart: overview of studies using genetic mouse models. Clin. Exp. Pharmacol. Physiol. 35(3), 335-341 (2008).
-
(2008)
Clin. Exp. Pharmacol. Physiol
, vol.35
, Issue.3
, pp. 335-341
-
-
Xiao, H.1
Zhang, Y.Y.2
-
27
-
-
34548832771
-
Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers
-
Liu W, Chang BL, Cramer S et al.: Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers. Clin. Cancer Res. 13(17), 5028-5033 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.17
, pp. 5028-5033
-
-
Liu, W.1
Chang, B.L.2
Cramer, S.3
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