Expression pattern of Wnt signaling components in the adult intestine

Gastroenterology

Volumn 129, Issue 2, 2005, Pages 626-638

  Gregorieff, Alex ^a   Pinto, Daniel ^a   Begthel, Harry ^a   Destrée, Olivier ^a   Kielman, Menno ^b   Clevers, Hans ^a  

^a HUBRECHT INSTITUTE   (Netherlands)

^b Delta Cell BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; LOW DENSITY LIPOPROTEIN RECEPTOR; LYMPHOID ENHANCER FACTOR 1; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3 PROTEIN; WNT6 PROTEIN; WNT9 PROTEIN;

ADENOMA; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; COLON; EMBRYO DEVELOPMENT; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTESTINE; MESENCHYME CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA PROBE; SIGNAL TRANSDUCTION; SMALL INTESTINE;

EID: 23244448347     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gastro.2005.06.007     Document Type: Article

References (71)

1. B.P. de Santa, G.R. van den Brink, D.J. Roberts Development and differentiation of the intestinal epithelium Cell Mol Life Sci 60 2003 1322 1332
2. E. Sancho, E. Batlle, H. Clevers Signaling pathways in intestinal development and cancer Annu Rev Cell Dev Biol 20 2004 695 723
3. C.Y. Logan, R. Nusse The Wnt signaling pathway in development and disease Annu Rev Cell Dev Biol 20 2004 781 810
4. K.M. Cadigan, R. Nusse Wnt signaling a common theme in animal development Genes Dev 11 1997 3286 3305
5. A. Wodarz, R. Nusse Mechanisms of Wnt signaling in development Annu Rev Cell Dev Biol 14 1998 59 88
6. P. Bhanot, M. Brink, C.H. Samos, J.C. Hsieh, Y. Wang, J.P. Macke, D. Andrew, J. Nathans, R. Nusse A new member of the frizzled family from Drosophila functions as a Wingless receptor Nature 382 1996 225 230
7. K.I. Pinson, J. Brennan, S. Monkley, B.J. Avery, W.C. Skarnes An LDL-receptor-related protein mediates Wnt signalling in mice Nature 407 2000 535 538
8. K. Tamai, M. Semenov, Y. Kato, R. Spokony, C. Liu, Y. Katsuyama, F. Hess, J.P. Saint-Jeannet, X. He LDL-receptor-related proteins in Wnt signal transduction Nature 407 2000 530 535
9. M. Wehrli, S.T. Dougan, K. Caldwell, L. O'Keefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, S. DiNardo Arrow encodes an LDL-receptor-related protein essential for Wingless signalling Nature 407 2000 527 530
10. J. Behrens, J.P. von Kries, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, W. Birchmeier Functional interaction of beta-catenin with the transcription factor LEF-1 Nature 382 1996 638 642
11. M. Molenaar, M. van de Wetering, M. Oosterwegel, J. Peterson-Maduro, S. Godsave, V. Korinek, J. Roose, O. Destree, H. Clevers XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos Cell 86 1996 391 399
12. D. Strutt Frizzled signalling and cell polarisation in Drosophila and vertebrates Development 130 2003 4501 4513
13. M.T. Veeman, J.D. Axelrod, R.T. Moon A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling Dev Cell 5 2003 367 377
14. R.H. Giles, J.H. van Es, H. Clevers Caught up in a Wnt storm Wnt signaling in cancer Biochim Biophys Acta 1653 2003 1 24
15. F.T. Kolligs, G. Bommer, B. Goke Wnt/beta-catenin/tcf signaling a critical pathway in gastrointestinal tumorigenesis Digestion 66 2002 131 144
16. S. Tejpar, J.J. Cassiman, E. Van Cutsem The molecular basis of colorectal cancer Acta Gastroenterol Belg 64 2001 249 254
17. O.J. Sansom, K.R. Reed, A.J. Hayes, H. Ireland, H. Brinkmann, I.P. Newton, E. Batlle, P. Simon-Assmann, H. Clevers, I.S. Nathke, A.R. Clarke, D.J. Winton Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration Genes Dev 18 2004 1385 1390
18. M. van de Wetering, E. Sancho, C. Verweij, W. de Lau, I. Oving, A. Hurlstone, K. van der Horn, E. Batlle, D. Coudreuse, A.P. Haramis, M. Tjon-Pon-Fong, P. Moerer, M. van den Born, G. Soete, S. Pals, M. Eilers, R. Medema, H. Clevers The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250
19. V. Korinek, N. Barker, P.J. Morin, D. van Wichen, R. de Weger, K.W. Kinzler, B. Vogelstein, H. Clevers Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma Science 275 1997 1784 1787
20. P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, K.W. Kinzler Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC Science 275 1997 1787 1790
21. V. Korinek, N. Barker, P. Moerer, E. van Donselaar, G. Huls, P.J. Peters, H. Clevers Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 Nat Genet 19 1998 379 383
22. F. Kuhnert, C.R. Davis, H.T. Wang, P. Chu, M. Lee, J. Yuan, R. Nusse, C.J. Kuo Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1 Proc Natl Acad Sci U S A 101 2004 266 271
23. D. Pinto, A. Gregorieff, H. Begthel, H. Clevers Canonical Wnt signals are essential for homeostasis of the intestinal epithelium Genes Dev 17 2003 1709 1713
24. E. Batlle, J.T. Henderson, H. Beghtel, M.M. van den Born, E. Sancho, G. Huls, J. Meeldijk, J. Robertson, M. van de Wetering, T. Pawson, H. Clevers Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB Cell 111 2002 251 263
25. H. Lickert, A. Kispert, S. Kutsch, R. Kemler Expression patterns of Wnt genes in mouse gut development Mech Dev 105 2001 181 184
26. H.J. McBride, B. Fatke, S.E. Fraser Wnt signaling components in the chicken intestinal tract Dev Biol 256 2003 18 33
27. N.A. Theodosiou, C.J. Tabin Wnt signaling during development of the gastrointestinal tract Dev Biol 259 2003 258 271
28. R.F. Holcombe, J.L. Marsh, M.L. Waterman, F. Lin, T. Milovanovic, T. Truong Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma Mol Pathol 55 2002 220 226
29. A.P. McMahon, A. Bradley The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain Cell 62 1990 1073 1085
30. B.J. Gavin, J.A. McMahon, A.P. McMahon Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development Genes Dev 4 1990 2319 2332
31. H. Roelink, R. Nusse Expression of two members of the Wnt family during mouse development-restricted temporal and spatial patterns in the developing neural tube Genes Dev 5 1991 381 388
32. P. Bouillet, M. Oulad-Abdelghani, S.J. Ward, S. Bronner, P. Chambon, P. Dolle A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid Mech Dev 58 1996 141 152
33. M. Richardson, D. Redmond, C.J. Watson, J.O. Mason Mouse Wnt8B is expressed in the developing forebrain and maps to chromosome 19 Mamm Genome 10 1999 923 925
34. M. Katoh Molecular cloning and expression of mouse Wnt14, and structural comparison between mouse Wnt14-Wnt3a gene cluster and human WNT14-WNT3A gene cluster Int J Mol Med 9 2002 221 227
35. J. Wang, G.M. Shackleford Murine Wnt10a and Wnt10b cloning and expression in developing limbs, face and skin of embryos and in adults Oncogene 13 1996 1537 1544
36. A. Kispert, S. Vainio, L. Shen, D.H. Rowitch, A.P. McMahon Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips Development 122 1996 3627 3637
37. Y. Wang, J.P. Macke, B.S. Abella, K. Andreasson, P. Worley, D.J. Gilbert, N.G. Copeland, N.A. Jenkins, J. Nathans A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled J Biol Chem 271 1996 4468 4476
38. A.P. Monaghan, P. Kioschis, W. Wu, A. Zuniga, D. Bock, A. Poustka, H. Delius, C. Niehrs Dickkopf genes are co-ordinately expressed in mesodermal lineages Mech Dev 87 1999 45 56
39. M. Oosterwegel, M. van de Wetering, J. Timmerman, A. Kruisbeek, O. Destree, F. Meijlink, H. Clevers Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis Development 118 1993 439 448
40. J. Qian, Z. Jiang, M. Li, P. Heaphy, Y.H. Liu, G.M. Shackleford Mouse Wnt9b transforming activity, tissue-specific expression, and evolution Genomics 81 2003 34 46
41. J.H. van Es, P. Jay, A. Gregorieff, M.E. van Gijn, S. Jonkheer, P. Hatzis, A. Thiele, M. van den Born, H. Begthel, T. Brabletz, M.M. Taketo, H. Clevers Wnt signalling induces maturation of Paneth cells in intestinal crypts Nat Cell Biol 7 2005 381 386
42. S.E. Jones, C. Jomary Secreted Frizzled-related proteins searching for relationships and patterns Bioessays 24 2002 811 820
43. Y. Kawano, R. Kypta Secreted antagonists of the Wnt signalling pathway J Cell Sci 116 2003 2627 2634
44. S.P. Bach, A.G. Renehan, C.S. Potten Stem cells the intestinal stem cell as a paradigm Carcinogenesis 21 2000 469 476
45. E. Marshman, C. Booth, C.S. Potten The intestinal epithelial stem cell Bioessays 24 2002 91 98
46. C.S. Potten The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice Cancer Metastasis Rev 11 1992 179 195
47. S. Nishimura, N. Wakabayashi, K. Toyoda, K. Kashima, S. Mitsufuji Expression of Musashi-1 in human normal colon crypt cells a possible stem cell marker of human colon epithelium Dig Dis Sci 48 2003 1523 1529
48. T. Kayahara, M. Sawada, S. Takaishi, H. Fukui, H. Seno, H. Fukuzawa, K. Suzuki, H. Hiai, R. Kageyama, H. Okano, T. Chiba Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine FEBS Lett 535 2003 131 135
49. C.S. Potten, C. Booth, G.L. Tudor, D. Booth, G. Brady, P. Hurley, G. Ashton, R. Clarke, S. Sakakibara, H. Okano Identification of a putative intestinal stem cell and early lineage marker; musashi-1 Differentiation 71 2003 28 41
50. A. Bafico, G. Liu, A. Yaniv, A. Gazit, S.A. Aaronson Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow Nat Cell Biol 3 2001 683 686
51. M. Cebrat, L. Strzadala, P. Kisielow Wnt inhibitory factor-1 a candidate for a new player in tumorigenesis of intestinal epithelial cells Cancer Lett 206 2004 107 113
52. M.L. Waterman Lymphoid enhancer factor/T cell factor expression in colorectal cancer Cancer Metastasis Rev 23 2004 41 52
53. J. Roose, G. Huls, M. van Beest, P. Moerer, K. van der Horn, R. Goldschmeding, T. Logtenberg, H. Clevers Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1 Science 285 1999 1923 1926
54. S. Verbeek, D. Izon, F. Hofhuis, E. Robanus-Maandag, H. te Riele, M. van de Wetering, M. Oosterwegel, A. Wilson, H.R. MacDonald, H. Clevers An HMG-box-containing T-cell factor required for thymocyte differentiation Nature 374 1995 70 74
55. K. Hovanes, T.W. Li, J.E. Munguia, T. Truong, T. Milovanovic, M.J. Lawrence, R.F. Holcombe, M.L. Waterman Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer Nat Genet 28 2001 53 57
56. V. Korinek, N. Barker, K. Willert, M. Molenaar, J. Roose, G. Wagenaar, M. Markman, W. Lamers, O. Destree, H. Clevers Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse Mol Cell Biol 18 1998 1248 1256
57. P. Andreu, S. Colnot, C. Godard, S. Gad, P. Chafey, M. Niwa-Kawakita, P. Laurent-Puig, A. Kahn, S. Robine, C. Perret, B. Romagnolo Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine Development 132 2005 1443 1451
58. L. Ouko, T.R. Ziegler, L.H. Gu, L.M. Eisenberg, V.W. Yang Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells J Biol Chem 279 2004 26707 26715
59. M. van de Wetering, E. Sancho, C. Verweij, W. de Lau, I. Oving, A. Hurlstone, K. van der Horn, E. Batlle, D. Coudreuse, A.P. Haramis, M. Tjon-Pon-Fong, P. Moerer, M. van den Born, G. Soete, S. Pals, M. Eilers, R. Medema, H. Clevers The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250
60. L. Topol, X. Jiang, H. Choi, L. Garrett-Beal, P.J. Carolan, Y. Yang Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation J Cell Biol 162 2003 899 908
61. W. Chen, D. ten Berge, J. Brown, S. Ahn, L.A. Hu, W.E. Miller, M.G. Caron, L.S. Barak, R. Nusse, R.J. Lefkowitz Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4 Science 301 2003 1391 1394
62. N. Guo, C. Hawkins, J. Nathans Frizzled6 controls hair patterning in mice Proc Natl Acad Sci U S A 101 2004 9277 9281
63. T. Golan, A. Yaniv, A. Bafico, G. Liu, A. Gazit The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascade J Biol Chem 279 2004 14879 14888
64. G.M. Caldwell, C. Jones, K. Gensberg, S. Jan, R.G. Hardy, P. Byrd, S. Chughtai, Y. Wallis, G.M. Matthews, D.G. Morton The Wnt antagonist sFRP1 in colorectal tumorigenesis Cancer Res 64 2004 883 888
65. H. Suzuki, D.N. Watkins, K.W. Jair, K.E. Schuebel, S.D. Markowitz, C.W. Dong, T.P. Pretlow, B. Yang, Y. Akiyama, M. Van Engeland, M. Toyota, T. Tokino, Y. Hinoda, K. Imai, J.G. Herman, S.B. Baylin Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer Nat Genet 36 2004 417 422
66. V.E. Krupnik, J.D. Sharp, C. Jiang, K. Robison, T.W. Chickering, L. Amaravadi, D.E. Brown, D. Guyot, G. Mays, K. Leiby, B. Chang, T. Duong, A.D. Goodearl, D.P. Gearing, S.Y. Sokol, S.A. McCarthy Functional and structural diversity of the human Dickkopf gene family Gene 238 1999 301 313
67. B. Mao, C. Niehrs Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling Gene 302 2003 179 183
68. B.K. Brott, S.Y. Sokol Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins Mol Cell Biol 22 2002 6100 6110
69. W. Wu, A. Glinka, H. Delius, C. Niehrs Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling Curr Biol 10 2000 1611 1614
70. J. Roose, M. Molenaar, J. Peterson, J. Hurenkamp, H. Brantjes, P. Moerer, M. van de Wetering, O. Destree, H. Clevers The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors Nature 395 1998 608 612
71. B.J. Merrill, H.A. Pasolli, L. Polak, M. Rendl, M.J. Garcia-Garcia, K.V. Anderson, E. Fuchs Tcf3 a transcriptional regulator of axis induction in the early embryo Development 131 2004 263 274