-
1
-
-
0037376199
-
Histone and chromatin cross-talk
-
Fischle, W., Wang, Y. & Allis, C.D. Histone and chromatin cross-talk. Curr. Opin. Cell Biol. 15, 172-188 (2003).
-
(2003)
Curr. Opin. Cell Biol
, vol.15
, pp. 172-188
-
-
Fischle, W.1
Wang, Y.2
Allis, C.D.3
-
2
-
-
15744396813
-
The key to development: Interpreting the histone code?
-
Margueron, R., Trojer, P. & Reinberg, D. The key to development: interpreting the histone code? Curr. Opin. Genet. Dev. 15, 163-176 (2005).
-
(2005)
Curr. Opin. Genet. Dev
, vol.15
, pp. 163-176
-
-
Margueron, R.1
Trojer, P.2
Reinberg, D.3
-
3
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
Martin, C. & Zhang, Y. The diverse functions of histone lysine methylation. Nature Rev. Mol. Cell Biol. 6, 838-849 (2005).
-
(2005)
Nature Rev. Mol. Cell Biol
, vol.6
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
4
-
-
24144475284
-
Reversing histone methylation
-
Bannister, A. J. & Kouzarides, T. Reversing histone methylation. Nature 436, 1103-1106 (2005).
-
(2005)
Nature
, vol.436
, pp. 1103-1106
-
-
Bannister, A.J.1
Kouzarides, T.2
-
5
-
-
33748434801
-
Histone demethylation and androgen-dependent transcription
-
Metzger, E., Wissmann, M. & Schule, R. Histone demethylation and androgen-dependent transcription. Curr. Opin. Genet. Dev. 16 513-517 (2006).
-
(2006)
Curr. Opin. Genet. Dev
, vol.16
, pp. 513-517
-
-
Metzger, E.1
Wissmann, M.2
Schule, R.3
-
6
-
-
18844373937
-
Transcriptional regulation by steroid receptor coactivator phosphorylation
-
Wu, R. C., Smith, C. L. & O'Malley, B. W. Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr. Rev. 26 393-399 (2005).
-
(2005)
Endocr. Rev
, vol.26
, pp. 393-399
-
-
Wu, R.C.1
Smith, C.L.2
O'Malley, B.W.3
-
7
-
-
0035962669
-
Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription
-
Dilworth, F. J. & Chambon, P. Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription. Oncogene 20, 3047-3054 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 3047-3054
-
-
Dilworth, F.J.1
Chambon, P.2
-
8
-
-
33744792310
-
Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
Rosenfeld, M. G., Lunyak, V. V. & Glass, C., K. Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 20, 1405-1428 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
9
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma
-
Pascual, G. et al. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437, 759-763 (2005).
-
(2005)
Nature
, vol.437
, pp. 759-763
-
-
Pascual, G.1
-
10
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans, R. M., Barish, G. D. & Wang, Y. X. PPARs and the complex journey to obesity. Nature Med. 10, 355-361 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
11
-
-
32644460092
-
From molecular action to physiological outputs. peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
-
Feige, J. N., Gelman, L., Michalik, L., Desvergne, B. & Wahli, W. From molecular action to physiological outputs. peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog. Lipid Res. 45, 120-159 (2006).
-
(2006)
Prog. Lipid Res
, vol.45
, pp. 120-159
-
-
Feige, J.N.1
Gelman, L.2
Michalik, L.3
Desvergne, B.4
Wahli, W.5
-
12
-
-
28944446431
-
The many faces of PPARgamma
-
Lehrke, M. & Lazar, M. A. The many faces of PPARgamma. Cell 123 993-999 (2005).
-
(2005)
Cell
, vol.123
, pp. 993-999
-
-
Lehrke, M.1
Lazar, M.A.2
-
13
-
-
0028180070
-
mPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz, P., Hu, E., Graves, R. A., Budavari, A. I. & Spiegelman, B. M. mPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8, 1224-1234 (1994).
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
14
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
-
Hu, E., Kim, J. B., Sarraf, P. & Spiegelman, B. M. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. Science 274, 2100-2103 (1996).
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
15
-
-
0037342133
-
Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade
-
Suzawa, M. et al. Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nature Cell Biol. 5 224-230 (2003).
-
(2003)
Nature Cell Biol
, vol.5
, pp. 224-230
-
-
Suzawa, M.1
-
16
-
-
13944283022
-
Longevity and lineages toward the integrative biology of degenerative diseases in heart, muscle, and bone
-
Chien, K. R. & Karsenty, G. Longevity and lineages toward the integrative biology of degenerative diseases in heart, muscle, and bone. Cell 120, 533-544 (2005).
-
(2005)
Cell
, vol.120
, pp. 533-544
-
-
Chien, K.R.1
Karsenty, G.2
-
17
-
-
0037673933
-
Control of osteoblast function and regulation of bone mass
-
Harada, S. & Rodan, G. A. Control of osteoblast function and regulation of bone mass. Nature 423, 349-355 (2003).
-
(2003)
Nature
, vol.423
, pp. 349-355
-
-
Harada, S.1
Rodan, G.A.2
-
18
-
-
33748680524
-
Genetic regulation of bone mass and susceptibility to osteoporosis
-
Ralston, S. H. & de Crombrugghe, B. Genetic regulation of bone mass and susceptibility to osteoporosis. Genes Dev. 20, 2492-2506 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 2492-2506
-
-
Ralston, S.H.1
de Crombrugghe, B.2
-
19
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J. et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382, 638-642 (1996).
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
-
20
-
-
0037214344
-
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/ beta-catenin signaling
-
Ishitani, T. et al. The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/ beta-catenin signaling. Mol. Cell. Biol. 23, 131-139 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 131-139
-
-
Ishitani, T.1
-
21
-
-
0041695485
-
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
-
Veeman, M. T., Axelrod, J. D. & Moon, R. T. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev. Cell 5, 367-377 (2003).
-
(2003)
Dev. Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
22
-
-
0037089626
-
-
Schultz, D. C., Ayyanathan, K., Negorev, D., Maul, G. G. & Rauscher, F. J. 3rd. SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16 919-932 (2002).
-
Schultz, D. C., Ayyanathan, K., Negorev, D., Maul, G. G. & Rauscher, F. J. 3rd. SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16 919-932 (2002).
-
-
-
-
23
-
-
0141992115
-
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
-
Wang, H. et al. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol. Cell 12, 475-487 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 475-487
-
-
Wang, H.1
-
24
-
-
4444239112
-
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome
-
Vissers, L. E. et al. Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nature Genet. 36, 955-957 (2004).
-
(2004)
Nature Genet
, vol.36
, pp. 955-957
-
-
Vissers, L.E.1
-
25
-
-
0036895537
-
Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis
-
Komatsu, Y. et al. Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis. Mech. Dev. 119, 239-249 (2002).
-
(2002)
Mech. Dev
, vol.119
, pp. 239-249
-
-
Komatsu, Y.1
-
26
-
-
0033600239
-
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF
-
Ishitani, T. et al. The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature 399, 798-802 (1999).
-
(1999)
Nature
, vol.399
, pp. 798-802
-
-
Ishitani, T.1
-
27
-
-
9644260361
-
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
-
Almind, K. & Kahn, C. R. Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes 53 3274-3285 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 3274-3285
-
-
Almind, K.1
Kahn, C.R.2
-
28
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPAR gamma
-
Mueller, E. et al. Terminal differentiation of human breast cancer through PPAR gamma. Mol. Cell 1, 465-470 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
-
29
-
-
23644431709
-
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
-
Hong, J. H. et al. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309, 1074-1078 (2005).
-
(2005)
Science
, vol.309
, pp. 1074-1078
-
-
Hong, J.H.1
-
30
-
-
33748748473
-
Thiazolidinedione use and bone loss in older diabetic adults
-
Schwartz, A. V. et al. Thiazolidinedione use and bone loss in older diabetic adults. J. Clin. Endocrinol. Metab. 91, 3349-3354 (2006).
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 3349-3354
-
-
Schwartz, A.V.1
-
31
-
-
2142652189
-
PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
-
Akune, T. et al. PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J. Clin. Invest. 113, 846-855 (2004).
-
(2004)
J. Clin. Invest
, vol.113
, pp. 846-855
-
-
Akune, T.1
-
32
-
-
0028157392
-
Wnt-3a regulates somite and tailbud formation in the mouse embryo
-
Takada, S. et al. Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev. 8, 174-189 (1994).
-
(1994)
Genes Dev
, vol.8
, pp. 174-189
-
-
Takada, S.1
-
33
-
-
20244373613
-
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
-
Glass, D. A. 2nd et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev. Cell 8 751-764 (2005).
-
(2005)
Dev. Cell
, vol.8
, pp. 751-764
-
-
Glass 2nd, D.A.1
-
34
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
Gong, Y. et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107, 513-523 (2001).
-
(2001)
Cell
, vol.107
, pp. 513-523
-
-
Gong, Y.1
-
35
-
-
0034637103
-
Inhibition of adipogenesis by Wnt signaling
-
Ross, S. E. et al. Inhibition of adipogenesis by Wnt signaling. Science 289, 950-953 (2000).
-
(2000)
Science
, vol.289
, pp. 950-953
-
-
Ross, S.E.1
-
36
-
-
0032938813
-
Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
-
Yamaguchi, T. P., Bradley, A., McMahon, A. P. & Jones, S. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223 (1999).
-
(1999)
Development
, vol.126
, pp. 1211-1223
-
-
Yamaguchi, T.P.1
Bradley, A.2
McMahon, A.P.3
Jones, S.A.4
-
37
-
-
0038046628
-
The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome
-
Kitagawa, H. et al. The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell 113, 905-917 (2003).
-
(2003)
Cell
, vol.113
, pp. 905-917
-
-
Kitagawa, H.1
-
38
-
-
18344388299
-
Nuclear receptor function requires a TFTC-type histone acetyl transferase complex
-
Yanagisawa, J. et al. Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol. Cell 9, 553-562 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 553-562
-
-
Yanagisawa, J.1
-
39
-
-
1042291299
-
The many colours of chromodomains
-
Brehm, A., Tufteland, K. R., Aasland, R. & Becker, P. B. The many colours of chromodomains. Bioessays 26, 133-140 (2004).
-
(2004)
Bioessays
, vol.26
, pp. 133-140
-
-
Brehm, A.1
Tufteland, K.R.2
Aasland, R.3
Becker, P.B.4
-
40
-
-
4344629704
-
Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation
-
Botrugno, O. A. et al. Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation. Mol. Cell 15, 499-509 (2004).
-
(2004)
Mol. Cell
, vol.15
, pp. 499-509
-
-
Botrugno, O.A.1
-
41
-
-
4644326231
-
Wnt/beta-catenin and estrogen signaling converge in vivo
-
Kouzmenko, A. P. et al. Wnt/beta-catenin and estrogen signaling converge in vivo. J. Biol. Chem. 279, 40255-40258 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 40255-40258
-
-
Kouzmenko, A.P.1
-
42
-
-
33746477054
-
Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad
-
Asahina, M., Valenta, T., Silhankova, M., Korinek, V. & Jindra, M. Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad. Dev. Cell 11 203-211 (2006).
-
(2006)
Dev. Cell
, vol.11
, pp. 203-211
-
-
Asahina, M.1
Valenta, T.2
Silhankova, M.3
Korinek, V.4
Jindra, M.5
-
43
-
-
32044448683
-
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepressibn pathway
-
Zhu, P. et al. Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepressibn pathway. Cell 124 615-629 (2006).
-
(2006)
Cell
, vol.124
, pp. 615-629
-
-
Zhu, P.1
-
44
-
-
33846690407
-
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors
-
Garcia-Bassets, I. et al. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell 128, 505-518 (2007).
-
(2007)
Cell
, vol.128
, pp. 505-518
-
-
Garcia-Bassets, I.1
-
45
-
-
34247348215
-
Opposing LSD1 complexes function in developmental gene activation and repression programmes
-
Wang, J. et al. Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446, 882-887 (2007).
-
(2007)
Nature
, vol.446
, pp. 882-887
-
-
Wang, J.1
-
46
-
-
26244448504
-
The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3
-
Kurahashi, T., Nomura, T., Kanei-Ishii, C., Shinkai, Y. & Ishii, S. The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3. Mol. Biol. Cell 16, 4705-4713 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4705-4713
-
-
Kurahashi, T.1
Nomura, T.2
Kanei-Ishii, C.3
Shinkai, Y.4
Ishii, S.5
-
47
-
-
0033212964
-
PPAR gamma mediates high-fat diet induced adipocyte hypertrophy and insulin resistance
-
Kubota, N. et al. PPAR gamma mediates high-fat diet induced adipocyte hypertrophy and insulin resistance. Mol. Cell 4, 597-609 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
-
48
-
-
0038100188
-
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
-
Ohtake, F. et al. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423, 545-550 (2003).
-
(2003)
Nature
, vol.423
, pp. 545-550
-
-
Ohtake, F.1
-
49
-
-
0032779039
-
Isolation and characterization of the distal promoter region of mouse Cbfa 1
-
Fujiwara, M. et al. Isolation and characterization of the distal promoter region of mouse Cbfa 1. Biochim. Biophys. Acta 1446 265-272 (1999).
-
(1999)
Biochim. Biophys. Acta
, vol.1446
, pp. 265-272
-
-
Fujiwara, M.1
-
50
-
-
27844520157
-
Ligand-induced transrepression by VDR through association of WSTF with acetylated histones
-
Fujiki, R. et al. Ligand-induced transrepression by VDR through association of WSTF with acetylated histones. EMBO J. 24, 3881-3894 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 3881-3894
-
-
Fujiki, R.1
|