Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases β-catenin levels and leads to cell dedifferentiation and insulin resistance

Journal of Biological Chemistry

Volumn 285, Issue 18, 2010, Pages 14031-14041

  Gustafson, Birgit ^a   Smith, Ulf ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTES; ADIPOGENIC; ADIPOSE CELLS; ADIPOSE TISSUE; CELL DEDIFFERENTIATION; CELL TYPES; GLUCOSE UPTAKE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SIGNALING; MYOFIBROBLASTS; OSTEOGENIC; PROTEIN EXPRESSIONS; SMOOTH MUSCLE ACTINS; TARGET CELLS; TRANSDIFFERENTIATION; UNDIFFERENTIATED CELLS;

GLUCOSE; INSULIN; SIGNALING;

LIGANDS;

ALPHA SMOOTH MUSCLE ACTIN; AXIN; BETA CATENIN; CELL PROTEIN; DICKKOPF 1 PROTEIN; INSULIN; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN DLK1; PROTEIN PREF 1; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; WNT PROTEIN; WNT10B PROTEIN; WNT3A PROTEIN;

ADIPOCYTE; ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL MATURATION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MYOFIBROBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ANTIGENS, DIFFERENTIATION; BETA CATENIN; CELL DEDIFFERENTIATION; HUMANS; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; L CELLS (CELL LINE); LDL-RECEPTOR RELATED PROTEINS; MICE; PPAR GAMMA; SIGNAL TRANSDUCTION; WNT PROTEINS;

MOUSE MAMMARY TUMOR VIRUS;

EID: 77951519413     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.102855     Document Type: Article

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