메뉴 건너뛰기




Volumn 22, Issue 6, 2009, Pages 724-739

Hear the wnt ror: How melanoma cells adjust to changes in Wnt

Author keywords

Clathrin; Endosome; Melanoma; Metastasis; Ror2; Wnt5A

Indexed keywords

BETA CATENIN; CYTOSKELETON PROTEIN; FRIZZLED PROTEIN; G PROTEIN COUPLED RECEPTOR; PROTEIN WNT 10A; PROTEIN WNT 10B; PROTEIN WNT 16; PROTEIN WNT 5B; PROTEIN WNT 6; PROTEIN WNT 7A; PROTEIN WNT 7B; PROTEIN WNT 8A; PROTEIN WNT 8B; PROTEIN WNT 9A; PROTEIN WNT 9B; PROTEOHEPARAN SULFATE; TUMOR ANTIGEN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT1 PROTEIN; WNT11 PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN;

EID: 70350100352     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2009.00627.x     Document Type: Review
Times cited : (73)

References (160)
  • 1
    • 33646188185 scopus 로고    scopus 로고
    • Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2
    • Ai, X., Do, A.T., Kusche-Gullberg, M., Lindahl, U., Lu, K. Emerson, C.P. Jr. (2006). Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J. Biol. Chem. 281, 4969 4976.
    • (2006) J. Biol. Chem. , vol.281 , pp. 4969-4976
    • Ai, X.1    Do, A.T.2    Kusche-Gullberg, M.3    Lindahl, U.4    Lu, K.5    Emerson, Jr.C.P.6
  • 2
    • 46749088657 scopus 로고    scopus 로고
    • The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src
    • Akbarzadeh, S., Wheldon, L.M., Sweet, S.M., Talma, S., Mardakheh, F.K. Heath, J.K. (2008). The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src. PLoS ONE 3, e1873.
    • (2008) PLoS ONE , vol.3 , pp. 1873
    • Akbarzadeh, S.1    Wheldon, L.M.2    Sweet, S.M.3    Talma, S.4    Mardakheh, F.K.5    Heath, J.K.6
  • 3
  • 4
    • 0024214349 scopus 로고
    • Amplification of the human putative oncogene INT1 in primary retinoblastoma tumors
    • Arheden, K., Tommerup, N., Mandahl, N. et al. (1988b). Amplification of the human putative oncogene INT1 in primary retinoblastoma tumors. Cytogenet. Cell Genet. 48, 174 177.
    • (1988) Cytogenet. Cell Genet. , vol.48 , pp. 174-177
    • Arheden, K.1    Tommerup, N.2    Mandahl, N.3
  • 5
    • 29344459785 scopus 로고    scopus 로고
    • Importance of P-cadherin, β-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma
    • Bachmann, I.M., Straume, O., Puntervoll, H.E., Kalvenes, M.B. Akslen, L.A. (2005). Importance of P-cadherin, β-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin. Cancer Res. 11, 8606 8614.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8606-8614
    • Bachmann, I.M.1    Straume, O.2    Puntervoll, H.E.3    Kalvenes, M.B.4    Akslen, L.A.5
  • 7
    • 0035152025 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
    • Baeg, G.H., Lin, X., Khare, N., Baumgartner, S. Perrimon, N. (2001). Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128, 87 94.
    • (2001) Development , vol.128 , pp. 87-94
    • Baeg, G.H.1    Lin, X.2    Khare, N.3    Baumgartner, S.4    Perrimon, N.5
  • 8
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Banziger, C., Soldini, D., Schutt, C., Zipperlen, P., Hausmann, G. Basler, K. (2006). Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125, 509 522.
    • (2006) Cell , vol.125 , pp. 509-522
    • Banziger, C.1    Soldini, D.2    Schutt, C.3    Zipperlen, P.4    Hausmann, G.5    Basler, K.6
  • 9
    • 33646123992 scopus 로고    scopus 로고
    • Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
    • Bartscherer, K., Pelte, N., Ingelfinger, D. Boutros, M. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125, 523 533.
    • (2006) Cell , vol.125 , pp. 523-533
    • Bartscherer, K.1    Pelte, N.2    Ingelfinger, D.3    Boutros, M.4
  • 10
    • 49549120607 scopus 로고    scopus 로고
    • GSK3beta inhibition promotes melanogenesis in mouse B16 melanoma cells and normal human melanocytes
    • Bellei, B., Flori, E., Izzo, E., Maresca, V. Picardo, M. (2008). GSK3beta inhibition promotes melanogenesis in mouse B16 melanoma cells and normal human melanocytes. Cell. Signal. 20, 1750 1761.
    • (2008) Cell. Signal. , vol.20 , pp. 1750-1761
    • Bellei, B.1    Flori, E.2    Izzo, E.3    Maresca, V.4    Picardo, M.5
  • 11
    • 33645750603 scopus 로고    scopus 로고
    • Redundant expression of canonical Wnt ligands in human breast cancer cell lines
    • Benhaj, K., Akcali, K.C. Ozturk, M. (2006). Redundant expression of canonical Wnt ligands in human breast cancer cell lines. Oncol. Rep. 15, 701 707.
    • (2006) Oncol. Rep. , vol.15 , pp. 701-707
    • Benhaj, K.1    Akcali, K.C.2    Ozturk, M.3
  • 13
    • 0034601455 scopus 로고    scopus 로고
    • Molecular classification of cutaneous malignant melanoma by gene expression profiling
    • Bittner, M., Meltzer, P., Chen, Y. et al. (2000). Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406, 536 540.
    • (2000) Nature , vol.406 , pp. 536-540
    • Bittner, M.1    Meltzer, P.2    Chen, Y.3
  • 14
    • 0026571604 scopus 로고
    • The biochemical properties and transforming potential of human Wnt-2 are similar to Wnt-1
    • Blasband, A., Schryver, B. Papkoff, J. (1992). The biochemical properties and transforming potential of human Wnt-2 are similar to Wnt-1. Oncogene 7, 153 161.
    • (1992) Oncogene , vol.7 , pp. 153-161
    • Blasband, A.1    Schryver, B.2    Papkoff, J.3
  • 15
    • 65549166003 scopus 로고    scopus 로고
    • Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis
    • Boyer, A., Paquet, M., Lague, M.N., Hermo, L. Boerboom, D. (2009). Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis. Carcinogenesis 30, 869 878.
    • (2009) Carcinogenesis , vol.30 , pp. 869-878
    • Boyer, A.1    Paquet, M.2    Lague, M.N.3    Hermo, L.4    Boerboom, D.5
  • 16
    • 0142188716 scopus 로고    scopus 로고
    • CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin
    • Cardones, A.R., Murakami, T. Hwang, S.T. (2003). CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. Cancer Res. 63, 6751 6757.
    • (2003) Cancer Res. , vol.63 , pp. 6751-6757
    • Cardones, A.R.1    Murakami, T.2    Hwang, S.T.3
  • 17
    • 0032900504 scopus 로고    scopus 로고
    • Dynamic patterns of gene expression in the developing pronephros of Xenopus laevis
    • Carroll, T.J., Wallingford, J.B. Vize, P.D. (1999). Dynamic patterns of gene expression in the developing pronephros of Xenopus laevis. Dev. Genet. 24, 199 207.
    • (1999) Dev. Genet. , vol.24 , pp. 199-207
    • Carroll, T.J.1    Wallingford, J.B.2    Vize, P.D.3
  • 18
    • 33745763860 scopus 로고    scopus 로고
    • The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line
    • Casagrande, G., Te Kronnie, G. Basso, G. (2006). The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line. Haematologica 91, 765 771.
    • (2006) Haematologica , vol.91 , pp. 765-771
    • Casagrande, G.1    Te Kronnie, G.2    Basso, G.3
  • 19
    • 48249098887 scopus 로고    scopus 로고
    • Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival
    • Chen, K., Fallen, S., Abaan, H.O. et al. (2008). Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. Pediatr. Blood Cancer 51, 349 355.
    • (2008) Pediatr. Blood Cancer , vol.51 , pp. 349-355
    • Chen, K.1    Fallen, S.2    Abaan, H.O.3
  • 20
    • 67449150167 scopus 로고    scopus 로고
    • A Wnt survival guide: From flies to human disease
    • Chien, A.J., Conrad, W.H. Moon, R.T. (2009a). A Wnt survival guide: from flies to human disease. J. Invest. Dermatol. 129, 1614 1627.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1614-1627
    • Chien, A.J.1    Conrad, W.H.2    Moon, R.T.3
  • 21
    • 59049101982 scopus 로고    scopus 로고
    • Activated Wnt/β-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
    • Chien, A.J., Moore, E.C., Lonsdorf, A.S. et al. (2009b). Activated Wnt/β-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc. Natl. Acad. Sci. USA 106, 1193 1198.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 1193-1198
    • Chien, A.J.1    Moore, E.C.2    Lonsdorf, A.S.3
  • 22
    • 53249090604 scopus 로고    scopus 로고
    • WNT5A expression increases during melanoma progression and correlates with outcome
    • Da Forno, P.D., Pringle, J.H., Hutchinson, P., et al. (2008). WNT5A expression increases during melanoma progression and correlates with outcome. Clin Cancer Res. 14, 5825 5832.
    • (2008) Clin Cancer Res. , vol.14 , pp. 5825-5832
    • Da Forno, P.D.1    Pringle, J.H.2    Hutchinson, P.3
  • 23
    • 0037454766 scopus 로고    scopus 로고
    • Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion
    • Dejmek, J., Dib, K., Jonsson, M. Andersson, T. (2003). Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion. Int. J. Cancer 103, 344 351.
    • (2003) Int. J. Cancer , vol.103 , pp. 344-351
    • Dejmek, J.1    Dib, K.2    Jonsson, M.3    Andersson, T.4
  • 24
    • 0035405257 scopus 로고    scopus 로고
    • Proteoglycans: Pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland
    • Delehedde, M., Lyon, M., Sergeant, N., Rahmoune, H. Fernig, D.G. (2001). Proteoglycans: pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland. J. Mammary Gland Biol. Neoplasia 6, 253 273.
    • (2001) J. Mammary Gland Biol. Neoplasia , vol.6 , pp. 253-273
    • Delehedde, M.1    Lyon, M.2    Sergeant, N.3    Rahmoune, H.4    Fernig, D.G.5
  • 25
    • 36249026528 scopus 로고    scopus 로고
    • Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development
    • Delmas, V., Beermann, F., Martinozzi, S. et al. (2007). Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 21, 2923 2935.
    • (2007) Genes Dev. , vol.21 , pp. 2923-2935
    • Delmas, V.1    Beermann, F.2    Martinozzi, S.3
  • 26
    • 0032486223 scopus 로고    scopus 로고
    • Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-alpha
    • Dennis, J.U., Dean, N.M., Bennett, C.F., Griffith, J.W., Lang, C.M. Welch, D.R. (1998). Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-alpha. Cancer Lett. 128, 65 70.
    • (1998) Cancer Lett. , vol.128 , pp. 65-70
    • Dennis, J.U.1    Dean, N.M.2    Bennett, C.F.3    Griffith, J.W.4    Lang, C.M.5    Welch, D.R.6
  • 27
    • 0035979765 scopus 로고    scopus 로고
    • Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase
    • Dhoot, G.K., Gustafsson, M.K., Ai, X., Sun, W., Standiford, D.M. Emerson, C.P. Jr. 2001). Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science 293, 1663 1666.
    • (2001) Science , vol.293 , pp. 1663-1666
    • Dhoot, G.K.1    Gustafsson, M.K.2    Ai, X.3    Sun, W.4    Standiford, D.M.5    Emerson, Jr.C.P.6
  • 28
    • 34447131518 scopus 로고    scopus 로고
    • The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition
    • Dissanayake, S.K., Wade, M., Johnson, C.E. et al. (2007). The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J. Biol. Chem. 282, 17259 17271.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17259-17271
    • Dissanayake, S.K.1    Wade, M.2    Johnson, C.E.3
  • 29
    • 57749098673 scopus 로고    scopus 로고
    • Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation
    • Dissanayake, S.K., Olkhanud, P.B., O'Connell, M.P. et al. (2008). Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 68, 10205 10214.
    • (2008) Cancer Res. , vol.68 , pp. 10205-10214
    • Dissanayake, S.K.1    Olkhanud, P.B.2    O'Connell, M.P.3
  • 30
    • 0042743826 scopus 로고    scopus 로고
    • BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma
    • Dong, J., Phelps, R.G., Qiao, R. et al. (2003). BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. Cancer Res. 63, 3883 3885.
    • (2003) Cancer Res. , vol.63 , pp. 3883-3885
    • Dong, J.1    Phelps, R.G.2    Qiao, R.3
  • 31
    • 0032569852 scopus 로고    scopus 로고
    • Control of neural crest cell fate by the Wnt signalling pathway
    • Dorsky, R.I., Moon, R.T. Raible, D.W. (1998). Control of neural crest cell fate by the Wnt signalling pathway. Nature 396, 370 373.
    • (1998) Nature , vol.396 , pp. 370-373
    • Dorsky, R.I.1    Moon, R.T.2    Raible, D.W.3
  • 32
    • 0034730204 scopus 로고    scopus 로고
    • Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development
    • Dunn, K.J., Williams, B.O., Li, Y. Pavan, W.J. (2000). Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development. Proc. Natl. Acad. Sci. USA 97, 10050 10055.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10050-10055
    • Dunn, K.J.1    Williams, B.O.2    Li, Y.3    Pavan, W.J.4
  • 34
    • 41149156857 scopus 로고    scopus 로고
    • Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism
    • Endo, Y., Beauchamp, E., Woods, D., Taylor, W.G., Toretsky, J.A., Uren, A. Rubin, J.S. (2008). Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol. Cell. Biol. 28, 2368 2379.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 2368-2379
    • Endo, Y.1    Beauchamp, E.2    Woods, D.3    Taylor, W.G.4    Toretsky, J.A.5    Uren, A.6    Rubin, J.S.7
  • 35
    • 33745758173 scopus 로고    scopus 로고
    • Defining the conditions for the generation of melanocytes from human embryonic stem cells
    • Fang, D., Leishear, K., Nguyen, T.K. et al. (2006). Defining the conditions for the generation of melanocytes from human embryonic stem cells. Stem Cells 24, 1668 1677.
    • (2006) Stem Cells , vol.24 , pp. 1668-1677
    • Fang, D.1    Leishear, K.2    Nguyen, T.K.3
  • 37
    • 62649157723 scopus 로고    scopus 로고
    • Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells
    • Ford, C.E., Ekstrom, E.J. Andersson, T. (2009a). Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells. Proc. Natl. Acad. Sci. USA 106, 3919 3924.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3919-3924
    • Ford, C.E.1    Ekstrom, E.J.2    Andersson, T.3
  • 38
    • 67649319056 scopus 로고    scopus 로고
    • The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERalpha negative breast cancer
    • Ford, C.E., Ekstrom, E.J., Howlin, J. Andersson, T. (2009b). The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERalpha negative breast cancer. Cell Cycle 8, 1838 1842.
    • (2009) Cell Cycle , vol.8 , pp. 1838-1842
    • Ford, C.E.1    Ekstrom, E.J.2    Howlin, J.3    Andersson, T.4
  • 39
    • 61349183717 scopus 로고    scopus 로고
    • Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma
    • Fukukawa, C., Nagayama, S., Tsunoda, T., Toguchida, J., Nakamura, Y. Katagiri, T. (2009). Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma. Oncogene 28, 1110 1120.
    • (2009) Oncogene , vol.28 , pp. 1110-1120
    • Fukukawa, C.1    Nagayama, S.2    Tsunoda, T.3    Toguchida, J.4    Nakamura, Y.5    Katagiri, T.6
  • 40
    • 70349310357 scopus 로고    scopus 로고
    • Activation of Wnt5A signaling is required for CXCL12-mediated T-cell migration
    • Ghosh, M.C., Collins, G.D., Vandanmagsar, B. et al. (2009). Activation of Wnt5A signaling is required for CXCL12-mediated T-cell migration. Blood 114, 1366 1373.
    • (2009) Blood , vol.114 , pp. 1366-1373
    • Ghosh, M.C.1    Collins, G.D.2    Vandanmagsar, B.3
  • 41
    • 2442548880 scopus 로고    scopus 로고
    • The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. β-catenin signaling cascade
    • Golan, T., Yaniv, A., Bafico, A., Liu, G. Gazit, A. (2004). The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. β-catenin signaling cascade. J. Biol. Chem. 279, 14879 14888.
    • (2004) J. Biol. Chem. , vol.279 , pp. 14879-14888
    • Golan, T.1    Yaniv, A.2    Bafico, A.3    Liu, G.4    Gazit, A.5
  • 42
    • 33846138014 scopus 로고    scopus 로고
    • Sprinter: A novel transmembrane protein required for Wg secretion and signaling
    • Goodman, R.M., Thombre, S., Firtina, Z. et al. (2006). Sprinter: a novel transmembrane protein required for Wg secretion and signaling. Development 133, 4901 4911.
    • (2006) Development , vol.133 , pp. 4901-4911
    • Goodman, R.M.1    Thombre, S.2    Firtina, Z.3
  • 43
    • 33847016833 scopus 로고    scopus 로고
    • β-Catenin/TCF/LEF regulate expression of the short form human Cripto-1
    • Hamada, S., Watanabe, K., Hirota, M. et al. (2007). β-Catenin/TCF/ LEF regulate expression of the short form human Cripto-1. Biochem. Biophys. Res. Commun. 355, 240 244.
    • (2007) Biochem. Biophys. Res. Commun. , vol.355 , pp. 240-244
    • Hamada, S.1    Watanabe, K.2    Hirota, M.3
  • 44
    • 58749090591 scopus 로고    scopus 로고
    • Analysis of Wnt7a-stimulated JNK activity and cJun phosphorylation in non-small cell lung cancer cells
    • Heasley, L.E. Winn, R.A. (2008). Analysis of Wnt7a-stimulated JNK activity and cJun phosphorylation in non-small cell lung cancer cells. Methods Mol. Biol. 468, 187 196.
    • (2008) Methods Mol. Biol. , vol.468 , pp. 187-196
    • Heasley, L.E.1    Winn, R.A.2
  • 45
    • 0033818034 scopus 로고    scopus 로고
    • Lessons from melanocyte development for understanding the biological events in naevus and melanoma formation
    • Herlyn, M., Berking, C., Li, G. Satyamoorthy, K. (2000). Lessons from melanocyte development for understanding the biological events in naevus and melanoma formation. Melanoma Res. 10, 303 312.
    • (2000) Melanoma Res. , vol.10 , pp. 303-312
    • Herlyn, M.1    Berking, C.2    Li, G.3    Satyamoorthy, K.4
  • 46
    • 33745753404 scopus 로고    scopus 로고
    • Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature
    • Hoek, K.S., Schlegel, N.C., Brafford, P. et al. (2006). Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res. 19, 290 302.
    • (2006) Pigment Cell Res. , vol.19 , pp. 290-302
    • Hoek, K.S.1    Schlegel, N.C.2    Brafford, P.3
  • 47
    • 38849203228 scopus 로고    scopus 로고
    • In vivo switching of human melanoma cells between proliferative and invasive states
    • Hoek, K.S., Eichhoff, O.M., Schlegel, N.C. et al. (2008). In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Res. 68, 650 656.
    • (2008) Cancer Res. , vol.68 , pp. 650-656
    • Hoek, K.S.1    Eichhoff, O.M.2    Schlegel, N.C.3
  • 48
    • 0035819073 scopus 로고    scopus 로고
    • NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
    • Howe, C.L., Valletta, J.S., Rusnak, A.S. Mobley, W.C. (2001). NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron 32, 801 814.
    • (2001) Neuron , vol.32 , pp. 801-814
    • Howe, C.L.1    Valletta, J.S.2    Rusnak, A.S.3    Mobley, W.C.4
  • 50
    • 67649220610 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase revealed as a negative regulator of Wnt-β-catenin signaling
    • James, R.G., Biechele, T.L., Conrad, W.H. et al. (2009). Bruton's tyrosine kinase revealed as a negative regulator of Wnt-β-catenin signaling. Sci. Signal. 2, ra25.
    • (2009) Sci. Signal. , vol.2 , pp. 25
    • James, R.G.1    Biechele, T.L.2    Conrad, W.H.3
  • 51
    • 0041508536 scopus 로고    scopus 로고
    • Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad
    • Jeays-Ward, K., Hoyle, C., Brennan, J., Dandonneau, M., Alldus, G., Capel, B. Swain, A. (2003). Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad. Development 130, 3663 3670.
    • (2003) Development , vol.130 , pp. 3663-3670
    • Jeays-Ward, K.1    Hoyle, C.2    Brennan, J.3    Dandonneau, M.4    Alldus, G.5    Capel, B.6    Swain, A.7
  • 52
    • 54349124051 scopus 로고    scopus 로고
    • Zebrafish Wnt9b synteny and expression during first and second arch, heart, and pectoral fin bud morphogenesis
    • Jezewski, P.A., Fang, P.K., Payne-Ferreira, T.L. Yelick, P.C. (2008). Zebrafish Wnt9b synteny and expression during first and second arch, heart, and pectoral fin bud morphogenesis. Zebrafish 5, 169 177.
    • (2008) Zebrafish , vol.5 , pp. 169-177
    • Jezewski, P.A.1    Fang, P.K.2    Payne-Ferreira, T.L.3    Yelick, P.C.4
  • 53
    • 0034960540 scopus 로고    scopus 로고
    • Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells
    • Jonsson, M. Andersson, T. (2001). Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells. J. Cell Sci. 114, 2043 2053.
    • (2001) J. Cell Sci. , vol.114 , pp. 2043-2053
    • Jonsson, M.1    Andersson, T.2
  • 54
    • 0031829436 scopus 로고    scopus 로고
    • Regulation of Wnt5a expression in human mammary cells by protein kinase C activity and the cytoskeleton
    • Jonsson, M., Smith, K. Harris, A.L. (1998). Regulation of Wnt5a expression in human mammary cells by protein kinase C activity and the cytoskeleton. Br. J. Cancer 78, 430 438.
    • (1998) Br. J. Cancer , vol.78 , pp. 430-438
    • Jonsson, M.1    Smith, K.2    Harris, A.L.3
  • 55
    • 0037081290 scopus 로고    scopus 로고
    • Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas
    • Jonsson, M., Dejmek, J., Bendahl, P.O. Andersson, T. (2002). Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas. Cancer Res. 62, 409 416.
    • (2002) Cancer Res. , vol.62 , pp. 409-416
    • Jonsson, M.1    Dejmek, J.2    Bendahl, P.O.3    Andersson, T.4
  • 56
    • 33749045017 scopus 로고    scopus 로고
    • Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test
    • Juriloff, D.M., Harris, M.J., Mcmahon, A.P., Carroll, T.J. Lidral, A.C. (2006). Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test. Birth Defects Res. A Clin. Mol. Teratol. 76, 574 579.
    • (2006) Birth Defects Res. A Clin. Mol. Teratol. , vol.76 , pp. 574-579
    • Juriloff, D.M.1    Harris, M.J.2    McMahon, A.P.3    Carroll, T.J.4    Lidral, A.C.5
  • 58
    • 65549107322 scopus 로고    scopus 로고
    • A multi-marker assay to distinguish malignant melanomas from benign nevi
    • Kashani-Sabet, M., Rangel, J., Torabian, S., et al. (2009). A multi-marker assay to distinguish malignant melanomas from benign nevi. Proc. Natl. Acad. Sci. U S A. 106, 6268 6272.
    • (2009) Proc. Natl. Acad. Sci. U S A. , vol.106 , pp. 6268-6272
    • Kashani-Sabet, M.1    Rangel, J.2    Torabian, S.3
  • 59
    • 33644698339 scopus 로고    scopus 로고
    • WNT/PCP signaling pathway and human cancer (review)
    • Katoh, M. (2005). WNT/PCP signaling pathway and human cancer (review). Oncol. Rep. 14, 1583 1588.
    • (2005) Oncol. Rep. , vol.14 , pp. 1583-1588
    • Katoh, M.1
  • 60
    • 0029780535 scopus 로고    scopus 로고
    • Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family
    • Katoh, M., Hirai, M., Sugimura, T. Terada, M. (1996). Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family. Oncogene 13, 873 876.
    • (1996) Oncogene , vol.13 , pp. 873-876
    • Katoh, M.1    Hirai, M.2    Sugimura, T.3    Terada, M.4
  • 61
    • 34447126400 scopus 로고    scopus 로고
    • Activation of Wnt/β-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia
    • Khan, N.I., Bradstock, K.F. Bendall, L.J. (2007). Activation of Wnt/β-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia. Br. J. Haematol. 138, 338 348.
    • (2007) Br. J. Haematol. , vol.138 , pp. 338-348
    • Khan, N.I.1    Bradstock, K.F.2    Bendall, L.J.3
  • 62
    • 70349510642 scopus 로고    scopus 로고
    • Wnt2 acts as an angiogenic growth factor for non-sinusoidal endothelial cells and inhibits expression of stanniocalcin-1
    • doi:.
    • Klein, D., Demory, A., Peyre, F. et al. (2009). Wnt2 acts as an angiogenic growth factor for non-sinusoidal endothelial cells and inhibits expression of stanniocalcin-1. Angiogenesis doi :.
    • (2009) Angiogenesis
    • Klein, D.1    Demory, A.2    Peyre, F.3
  • 64
    • 0343293801 scopus 로고    scopus 로고
    • Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus
    • Kuhl, M., Sheldahl, L.C., Malbon, C.C. Moon, R.T. (2000a). Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus. J. Biol. Chem. 275, 12701 12711.
    • (2000) J. Biol. Chem. , vol.275 , pp. 12701-12711
    • Kuhl, M.1    Sheldahl, L.C.2    Malbon, C.C.3    Moon, R.T.4
  • 65
    • 0034214847 scopus 로고    scopus 로고
    • The Wnt/Ca2+ pathway: A new vertebrate Wnt signaling pathway takes shape
    • Kuhl, M., Sheldahl, L.C., Park, M., Miller, J.R. Moon, R.T. (2000b). The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet. 16, 279 283.
    • (2000) Trends Genet. , vol.16 , pp. 279-283
    • Kuhl, M.1    Sheldahl, L.C.2    Park, M.3    Miller, J.R.4    Moon, R.T.5
  • 67
    • 0031901224 scopus 로고    scopus 로고
    • Neural crest induction in Xenopus: Evidence for a two-signal model
    • Labonne, C. Bronner-Fraser, M. (1998). Neural crest induction in Xenopus: evidence for a two-signal model. Development 125, 2403 2414.
    • (1998) Development , vol.125 , pp. 2403-2414
    • Labonne, C.1    Bronner-Fraser, M.2
  • 68
    • 14544303647 scopus 로고    scopus 로고
    • Pax3 functions at a nodal point in melanocyte stem cell differentiation
    • Lang, D., Lu, M.M., Huang, L. et al. (2005). Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature 433, 884 887.
    • (2005) Nature , vol.433 , pp. 884-887
    • Lang, D.1    Lu, M.M.2    Huang, L.3
  • 69
    • 32944460267 scopus 로고    scopus 로고
    • The WNT/β-catenin pathway in melanoma
    • Larue, L. Delmas, V. (2006). The WNT/β-catenin pathway in melanoma. Front. Biosci. 11, 733 742.
    • (2006) Front. Biosci. , vol.11 , pp. 733-742
    • Larue, L.1    Delmas, V.2
  • 71
    • 54849432173 scopus 로고    scopus 로고
    • Wnt6 signaling regulates heart muscle development during organogenesis
    • Lavery, D.L., Martin, J., Turnbull, Y.D. Hoppler, S. (2008). Wnt6 signaling regulates heart muscle development during organogenesis. Dev. Biol. 323, 177 188.
    • (2008) Dev. Biol. , vol.323 , pp. 177-188
    • Lavery, D.L.1    Martin, J.2    Turnbull, Y.D.3    Hoppler, S.4
  • 72
    • 66049092616 scopus 로고    scopus 로고
    • Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells
    • Le Grand, F., Jones, A.E., Seale, V., Scime, A. Rudnicki, M.A. (2009). Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell 4, 535 547.
    • (2009) Cell Stem Cell , vol.4 , pp. 535-547
    • Le Grand, F.1    Jones, A.E.2    Seale, V.3    Scime, A.4    Rudnicki, M.A.5
  • 73
    • 0036303142 scopus 로고    scopus 로고
    • A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility
    • Legg, J.W., Lewis, C.A., Parsons, M., Ng, T. Isacke, C.M. (2002). A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility. Nat. Cell Biol. 4, 399 407.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 399-407
    • Legg, J.W.1    Lewis, C.A.2    Parsons, M.3    Ng, T.4    Isacke, C.M.5
  • 74
    • 33748792234 scopus 로고    scopus 로고
    • LRP5/6 in Wnt signaling and tumorigenesis
    • Li, Y. Bu, G. (2005). LRP5/6 in Wnt signaling and tumorigenesis. Future Oncol. 1, 673 681.
    • (2005) Future Oncol. , vol.1 , pp. 673-681
    • Li, Y.1    Bu, G.2
  • 75
    • 39849091185 scopus 로고    scopus 로고
    • Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with FZD2
    • Li, C., Chen, H., Hu, L. et al. (2008). Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with FZD2. BMC Mol. Biol. 9, 11.
    • (2008) BMC Mol. Biol. , vol.9 , pp. 11
    • Li, C.1    Chen, H.2    Hu, L.3
  • 76
    • 0034253918 scopus 로고    scopus 로고
    • Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila
    • DOI 10.1016/S0945-053X(00)00073-1, PII S0945053X00000731
    • Lin, X. Perrimon, N. (2000). Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biol. 19, 303 307. (Pubitemid 30665653)
    • (2000) Matrix Biology , vol.19 , Issue.4 , pp. 303-307
    • Lin, X.1    Perrimon, N.2
  • 78
    • 33846597125 scopus 로고    scopus 로고
    • The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation
    • Liu, Y., Bhat, R.A., Seestaller-Wehr, L.M. et al. (2007). The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation. Mol. Endocrinol. 21, 376 387.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 376-387
    • Liu, Y.1    Bhat, R.A.2    Seestaller-Wehr, L.M.3
  • 79
    • 33646195306 scopus 로고    scopus 로고
    • Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling
    • Lopes, C.C., Dietrich, C.P. Nader, H.B. (2006). Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling. Braz. J. Med. Biol. Res. 39, 157 167.
    • (2006) Braz. J. Med. Biol. Res. , vol.39 , pp. 157-167
    • Lopes, C.C.1    Dietrich, C.P.2    Nader, H.B.3
  • 80
    • 34547103285 scopus 로고    scopus 로고
    • Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
    • Macleod, R.J., Hayes, M. Pacheco, I. (2007). Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G403 G411.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293
    • MacLeod, R.J.1    Hayes, M.2    Pacheco, I.3
  • 81
    • 24344443662 scopus 로고    scopus 로고
    • Overexpression of the Wnt5b gene in leiomyoma cells: Implications for a role of the Wnt signaling pathway in the uterine benign tumor
    • Mangioni, S., Vigano, P., Lattuada, D., Abbiati, A., Vignali, M. Di Blasio, A.M. (2005). Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor. J. Clin. Endocrinol. Metab. 90, 5349 5355.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 5349-5355
    • Mangioni, S.1    Vigano, P.2    Lattuada, D.3    Abbiati, A.4    Vignali, M.5    Di Blasio, A.M.6
  • 82
    • 0028258134 scopus 로고
    • Effect of protein kinase C inhibitors on invasiveness of human melanoma clones expressing different levels of protein kinase C isoenzymes
    • Mapelli, E., Banfi, P., Sala, E., Sensi, M., Supino, R., Zunino, F. Gambetta, R.A. (1994). Effect of protein kinase C inhibitors on invasiveness of human melanoma clones expressing different levels of protein kinase C isoenzymes. Int. J. Cancer 57, 281 286.
    • (1994) Int. J. Cancer , vol.57 , pp. 281-286
    • Mapelli, E.1    Banfi, P.2    Sala, E.3    Sensi, M.4    Supino, R.5    Zunino, F.6    Gambetta, R.A.7
  • 83
    • 70349575235 scopus 로고    scopus 로고
    • Conditional mutations of β-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation
    • doi:.
    • Martinez, G., Wijesinghe, M., Turner, K.N. et al. (2009). Conditional mutations of β-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. Invest. Ophthalmol. Vis. Sci. doi :.
    • (2009) Invest. Ophthalmol. Vis. Sci.
    • Martinez, G.1    Wijesinghe, M.2    Turner, K.N.3
  • 84
    • 46049104677 scopus 로고    scopus 로고
    • Wnt9a secreted from the walls of hepatic sinusoids is essential for morphogenesis, proliferation, and glycogen accumulation of chick hepatic epithelium
    • In Press.
    • Matsumoto, K., Miki, R., Nakayama, M., Tatsumi, N. Yokouchi, Y. (2008). Wnt9a secreted from the walls of hepatic sinusoids is essential for morphogenesis, proliferation, and glycogen accumulation of chick hepatic epithelium. Dev. Biol. 319, 234 247. In Press.
    • (2008) Dev. Biol. , vol.319 , pp. 234-247
    • Matsumoto, K.1    Miki, R.2    Nakayama, M.3    Tatsumi, N.4    Yokouchi, Y.5
  • 85
    • 24044490922 scopus 로고    scopus 로고
    • Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis
    • Mazieres, J., You, L., He, B. et al. (2005). Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene 24, 5396 5400.
    • (2005) Oncogene , vol.24 , pp. 5396-5400
    • Mazieres, J.1    You, L.2    He, B.3
  • 86
    • 49149118760 scopus 로고    scopus 로고
    • The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells
    • Melchior, K., Weiss, J., Zaehres, H. et al. (2008). The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biol. Chem. 389, 897 903.
    • (2008) Biol. Chem. , vol.389 , pp. 897-903
    • Melchior, K.1    Weiss, J.2    Zaehres, H.3
  • 87
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context
    • Mikels, A.J. Nusse, R. (2006). Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context. PLoS Biol. 4, e115.
    • (2006) PLoS Biol. , vol.4 , pp. 115
    • Mikels, A.J.1    Nusse, R.2
  • 88
    • 60749136421 scopus 로고    scopus 로고
    • Expression of Wnt4 in human pituitary adenomas regulates activation of the β-catenin-independent pathway
    • Miyakoshi, T., Takei, M., Kajiya, H., Egashira, N., Takekoshi, S., Teramoto, A. Osamura, R.Y. (2008). Expression of Wnt4 in human pituitary adenomas regulates activation of the β-catenin-independent pathway. Endocr. Pathol. 19, 261 273.
    • (2008) Endocr. Pathol. , vol.19 , pp. 261-273
    • Miyakoshi, T.1    Takei, M.2    Kajiya, H.3    Egashira, N.4    Takekoshi, S.5    Teramoto, A.6    Osamura, R.Y.7
  • 89
    • 67449103899 scopus 로고    scopus 로고
    • Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma
    • Morioka, K., Tanikawa, C., Ochi, K. et al. (2009). Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Sci. 100, 1227 1233.
    • (2009) Cancer Sci. , vol.100 , pp. 1227-1233
    • Morioka, K.1    Tanikawa, C.2    Ochi, K.3
  • 90
    • 10744230854 scopus 로고    scopus 로고
    • β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation
    • Morkel, M., Huelsken, J., Wakamiya, M. et al. (2003). β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development 130, 6283 6294.
    • (2003) Development , vol.130 , pp. 6283-6294
    • Morkel, M.1    Huelsken, J.2    Wakamiya, M.3
  • 91
    • 42349113210 scopus 로고    scopus 로고
    • The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology
    • Nakamura, T. Matsumoto, K. (2008). The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology. J. Cell Mol. Med. 12, 391 408.
    • (2008) J. Cell Mol. Med. , vol.12 , pp. 391-408
    • Nakamura, T.1    Matsumoto, K.2
  • 92
  • 93
    • 70450233732 scopus 로고    scopus 로고
    • WNT10A missense mutation associated with a complete Odonto-Onycho-Dermal Dysplasia syndrome
    • doi:.
    • Nawaz, S., Klar, J., Wajid, M. et al. (2009). WNT10A missense mutation associated with a complete Odonto-Onycho-Dermal Dysplasia syndrome. Eur. J. Hum. Genet. doi :.
    • (2009) Eur. J. Hum. Genet.
    • Nawaz, S.1    Klar, J.2    Wajid, M.3
  • 94
    • 34848922753 scopus 로고    scopus 로고
    • Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation
    • Nemeth, M.J., Topol, L., Anderson, S.M., Yang, Y. Bodine, D.M. (2007). Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proc. Natl. Acad. Sci. USA 104, 15436 15441.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 15436-15441
    • Nemeth, M.J.1    Topol, L.2    Anderson, S.M.3    Yang, Y.4    Bodine, D.M.5
  • 95
    • 34447327864 scopus 로고    scopus 로고
    • Generating quiescent stem cells
    • Nishikawa, S. Osawa, M. (2007). Generating quiescent stem cells. Pigment Cell Res. 20, 263 270.
    • (2007) Pigment Cell Res. , vol.20 , pp. 263-270
    • Nishikawa, S.1    Osawa, M.2
  • 96
    • 33751215213 scopus 로고    scopus 로고
    • Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration
    • Nishita, M., Yoo, S.K., Nomachi, A. et al. (2006). Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration. J. Cell Biol. 175, 555 562.
    • (2006) J. Cell Biol. , vol.175 , pp. 555-562
    • Nishita, M.1    Yoo, S.K.2    Nomachi, A.3
  • 97
    • 54249099723 scopus 로고    scopus 로고
    • Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein Filamin A
    • Nomachi, A., Nishita, M., Inaba, D., Enomoto, M., Hamasaki, M. Minami, Y. (2008). Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein Filamin A. J. Biol. Chem. 283, 27973 27981.
    • (2008) J. Biol. Chem. , vol.283 , pp. 27973-27981
    • Nomachi, A.1    Nishita, M.2    Inaba, D.3    Enomoto, M.4    Hamasaki, M.5    Minami, Y.6
  • 98
    • 0037278743 scopus 로고    scopus 로고
    • Transcriptional regulation of metastasis-related genes in human melanoma
    • DOI 10.1023/A:1022991302172
    • Nyormoi, O. Bar-Eli, M. (2003). Transcriptional regulation of metastasis-related genes in human melanoma. Clin. Exp. Metastasis 20, 251 263. (Pubitemid 36513229)
    • (2003) Clinical and Experimental Metastasis , vol.20 , Issue.3 , pp. 251-263
    • Nyormoi, O.1    Bar-Eli, M.2
  • 100
    • 67449128692 scopus 로고    scopus 로고
    • Wnt5A activates the calpain-mediated cleavage of Filamin A
    • O'Connell, M.P., Fiori, J.L., Baugher, K.M. et al. (2009a). Wnt5A activates the calpain-mediated cleavage of Filamin A. J. Invest. Dermatol. 129, 1782 1789.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1782-1789
    • O'Connell, M.P.1    Fiori, J.L.2    Baugher, K.M.3
  • 101
    • 70350127049 scopus 로고    scopus 로고
    • HSPG modulation of WNT5A signal transduction in metastatic melanoma cells
    • doi:.
    • O'Connell, M.P., Fiori, J.L., Kershner, E.K., et al. (2009b). HSPG modulation of WNT5A signal transduction in metastatic melanoma cells. J. Biol. Chem. doi :.
    • (2009) J. Biol. Chem.
    • O'Connell, M.P.1    Fiori, J.L.2    Kershner, E.K.3
  • 102
    • 73849098667 scopus 로고    scopus 로고
    • The Orphan Tyrosine Kinase Receptor, ROR2, Mediates Wnt5A Signaling in Metastatic Melanoma
    • doi:.
    • O'Connell, M.P., Fiori, J.L., Xu, M., et al. (2009c). The Orphan Tyrosine Kinase Receptor, ROR2, Mediates Wnt5A Signaling in Metastatic Melanoma. Oncogene doi :.
    • (2009) Oncogene
    • O'Connell, M.P.1    Fiori, J.L.2    Xu, M.3
  • 103
    • 10744219743 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway
    • Oishi, I., Suzuki, H., Onishi, N. et al. (2003). The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells 8, 645 654.
    • (2003) Genes Cells , vol.8 , pp. 645-654
    • Oishi, I.1    Suzuki, H.2    Onishi, N.3
  • 104
    • 38749101987 scopus 로고    scopus 로고
    • Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases
    • Okuyama, R., Tagami, H. Aiba, S. (2008). Notch signaling: its role in epidermal homeostasis and in the pathogenesis of skin diseases. J. Dermatol. Sci. 49, 187 194.
    • (2008) J. Dermatol. Sci. , vol.49 , pp. 187-194
    • Okuyama, R.1    Tagami, H.2    Aiba, S.3
  • 105
    • 33845356420 scopus 로고    scopus 로고
    • Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
    • Ordway, J.M., Bedell, J.A., Citek, R.W. et al. (2006). Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets. Carcinogenesis 27, 2409 2423.
    • (2006) Carcinogenesis , vol.27 , pp. 2409-2423
    • Ordway, J.M.1    Bedell, J.A.2    Citek, R.W.3
  • 107
    • 62449186707 scopus 로고    scopus 로고
    • EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style
    • Parri, M., Taddei, M.L., Bianchini, F., Calorini, L. Chiarugi, P. (2009). EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style. Cancer Res. 69, 2072 2081.
    • (2009) Cancer Res. , vol.69 , pp. 2072-2081
    • Parri, M.1    Taddei, M.L.2    Bianchini, F.3    Calorini, L.4    Chiarugi, P.5
  • 109
    • 0141884398 scopus 로고    scopus 로고
    • Wnt ligand expression in malignant melanoma: Pilot study indicating correlation with histopathological features
    • Pham, K., Milovanovic, T., Barr, R.J., Truong, T. Holcombe, R.F. (2003). Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features. Mol. Pathol. 56, 280 285.
    • (2003) Mol. Pathol. , vol.56 , pp. 280-285
    • Pham, K.1    Milovanovic, T.2    Barr, R.J.3    Truong, T.4    Holcombe, R.F.5
  • 111
    • 0037228055 scopus 로고    scopus 로고
    • High frequency of BRAF mutations in nevi
    • Pollock, P.M., Harper, U.L., Hansen, K.S. et al. (2003). High frequency of BRAF mutations in nevi. Nat. Genet. 33, 19 20.
    • (2003) Nat. Genet. , vol.33 , pp. 19-20
    • Pollock, P.M.1    Harper, U.L.2    Hansen, K.S.3
  • 112
    • 33748881058 scopus 로고    scopus 로고
    • Molecular biology of malignant melanoma and other cutaneous tumors
    • Pons, M. Quintanilla, M. (2006). Molecular biology of malignant melanoma and other cutaneous tumors. Clin. Transl. Oncol. 8, 466 474.
    • (2006) Clin. Transl. Oncol. , vol.8 , pp. 466-474
    • Pons, M.1    Quintanilla, M.2
  • 113
    • 46049093965 scopus 로고    scopus 로고
    • Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme
    • Rajagopal, J., Carroll, T.J., Guseh, J.S. et al. (2008). Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development 135, 1625 1634.
    • (2008) Development , vol.135 , pp. 1625-1634
    • Rajagopal, J.1    Carroll, T.J.2    Guseh, J.S.3
  • 114
    • 0032891826 scopus 로고    scopus 로고
    • Partial cloning and assignment of WNT6 to human chromosome band 2q35 by in situ hybridization
    • Rankin, J., Strachan, T., Lako, M. Lindsay, S. (1999). Partial cloning and assignment of WNT6 to human chromosome band 2q35 by in situ hybridization. Cytogenet. Cell Genet. 84, 50 52.
    • (1999) Cytogenet. Cell Genet. , vol.84 , pp. 50-52
    • Rankin, J.1    Strachan, T.2    Lako, M.3    Lindsay, S.4
  • 115
    • 42449139493 scopus 로고    scopus 로고
    • Impact of sentinel lymphadenectomy on survival in a murine model of melanoma
    • Rebhun, R.B., Lazar, A.J., Fidler, I.J. Gershenwald, J.E. (2008). Impact of sentinel lymphadenectomy on survival in a murine model of melanoma. Clin. Exp. Metastasis 25, 191 199.
    • (2008) Clin. Exp. Metastasis , vol.25 , pp. 191-199
    • Rebhun, R.B.1    Lazar, A.J.2    Fidler, I.J.3    Gershenwald, J.E.4
  • 116
    • 0037179894 scopus 로고    scopus 로고
    • Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    • Rhee, C.S., Sen, M., Lu, D. et al. (2002). Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene 21, 6598 6605.
    • (2002) Oncogene , vol.21 , pp. 6598-6605
    • Rhee, C.S.1    Sen, M.2    Lu, D.3
  • 117
    • 0028848301 scopus 로고
    • Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb
    • Riddle, R.D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T.M. Tabin, C. (1995). Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631 640.
    • (1995) Cell , vol.83 , pp. 631-640
    • Riddle, R.D.1    Ensini, M.2    Nelson, C.3    Tsuchida, T.4    Jessell, T.M.5    Tabin, C.6
  • 118
    • 0023653232 scopus 로고
    • The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
    • Rijsewijk, F., Schuermann, M., Wagenaar, E., Parren, P., Weigel, D. Nusse, R. (1987). The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 50, 649 657.
    • (1987) Cell , vol.50 , pp. 649-657
    • Rijsewijk, F.1    Schuermann, M.2    Wagenaar, E.3    Parren, P.4    Weigel, D.5    Nusse, R.6
  • 119
    • 0032937232 scopus 로고    scopus 로고
    • Frequent nuclear/cytoplasmic localization of β-catenin without exon 3 mutations in malignant melanoma
    • Rimm, D.L., Caca, K., Hu, G., Harrison, F.B. Fearon, E.R. (1999). Frequent nuclear/cytoplasmic localization of β-catenin without exon 3 mutations in malignant melanoma. Am. J. Pathol. 154, 325 329.
    • (1999) Am. J. Pathol. , vol.154 , pp. 325-329
    • Rimm, D.L.1    Caca, K.2    Hu, G.3    Harrison, F.B.4    Fearon, E.R.5
  • 120
    • 0035976899 scopus 로고    scopus 로고
    • Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells
    • Robledo, M.M., Bartolome, R.A., Longo, N. et al. (2001). Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells. J. Biol. Chem. 276, 45098 45105.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45098-45105
    • Robledo, M.M.1    Bartolome, R.A.2    Longo, N.3
  • 121
    • 0027291419 scopus 로고
    • Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene
    • Roelink, H., Wang, J., Black, D.M., Solomon, E. Nusse, R. (1993). Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene. Genomics 17, 790 792.
    • (1993) Genomics , vol.17 , pp. 790-792
    • Roelink, H.1    Wang, J.2    Black, D.M.3    Solomon, E.4    Nusse, R.5
  • 122
    • 17644421824 scopus 로고    scopus 로고
    • Effects on proliferation and melanogenesis by inhibition of mutant BRAF and expression of wild-type INK4A in melanoma cells
    • Rotolo, S., Diotti, R., Gordon, R.E. et al. (2005). Effects on proliferation and melanogenesis by inhibition of mutant BRAF and expression of wild-type INK4A in melanoma cells. Int. J. Cancer 115, 164 169.
    • (2005) Int. J. Cancer , vol.115 , pp. 164-169
    • Rotolo, S.1    Diotti, R.2    Gordon, R.E.3
  • 123
    • 0030900696 scopus 로고    scopus 로고
    • Stabilization of β-catenin by genetic defects in melanoma cell lines
    • Rubinfeld, B., Robbins, P., El-Gamil, M., Albert, I., Porfiri, E. Polakis, P. (1997). Stabilization of β-catenin by genetic defects in melanoma cell lines. Science 275, 1790 1792.
    • (1997) Science , vol.275 , pp. 1790-1792
    • Rubinfeld, B.1    Robbins, P.2    El-Gamil, M.3    Albert, I.4    Porfiri, E.5    Polakis, P.6
  • 124
    • 58149190789 scopus 로고    scopus 로고
    • The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility
    • Safholm, A., Tuomela, J., Rosenkvist, J., Dejmek, J., Harkonen, P. Andersson, T. (2008). The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin. Cancer Res. 14, 6556 6563.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6556-6563
    • Safholm, A.1    Tuomela, J.2    Rosenkvist, J.3    Dejmek, J.4    Harkonen, P.5    Andersson, T.6
  • 125
    • 0035433906 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region
    • Saitoh, T. Katoh, M. (2001). Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region. Int. J. Oncol. 19, 347 351.
    • (2001) Int. J. Oncol. , vol.19 , pp. 347-351
    • Saitoh, T.1    Katoh, M.2
  • 126
    • 0036726264 scopus 로고    scopus 로고
    • Expression and regulation of WNT5A and WNT5B in human cancer: Up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by β-estradiol in MCF-7 cells
    • Saitoh, T. Katoh, M. (2002). Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by β-estradiol in MCF-7 cells. Int. J. Mol. Med. 10, 345 349.
    • (2002) Int. J. Mol. Med. , vol.10 , pp. 345-349
    • Saitoh, T.1    Katoh, M.2
  • 127
    • 0032566307 scopus 로고    scopus 로고
    • Characterization of Wnt gene expression in murine skin: Possible involvement of epidermis-derived Wnt-4 in cutaneous epithelial-mesenchymal interactions
    • Saitoh, A., Hansen, L.A., Vogel, J.C. Udey, M.C. (1998). Characterization of Wnt gene expression in murine skin: possible involvement of epidermis-derived Wnt-4 in cutaneous epithelial-mesenchymal interactions. Exp. Cell Res. 243, 150 160.
    • (1998) Exp. Cell Res. , vol.243 , pp. 150-160
    • Saitoh, A.1    Hansen, L.A.2    Vogel, J.C.3    Udey, M.C.4
  • 128
    • 27744550696 scopus 로고    scopus 로고
    • Regulation of Slug transcription in embryonic ectoderm by β-catenin-Lef/Tcf and BMP-Smad signaling
    • Sakai, D., Tanaka, Y., Endo, Y., Osumi, N., Okamoto, H. Wakamatsu, Y. (2005). Regulation of Slug transcription in embryonic ectoderm by β-catenin-Lef/Tcf and BMP-Smad signaling. Dev. Growth Differ. 47, 471 482.
    • (2005) Dev. Growth Differ. , vol.47 , pp. 471-482
    • Sakai, D.1    Tanaka, Y.2    Endo, Y.3    Osumi, N.4    Okamoto, H.5    Wakamatsu, Y.6
  • 129
    • 0031596806 scopus 로고    scopus 로고
    • Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases
    • Saldanha, J., Singh, J. Mahadevan, D. (1998). Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases. Protein Sci. 7, 1632 1635.
    • (1998) Protein Sci. , vol.7 , pp. 1632-1635
    • Saldanha, J.1    Singh, J.2    Mahadevan, D.3
  • 130
    • 52049120639 scopus 로고    scopus 로고
    • The role of Wnt signalling in the development of somites and neural crest
    • Schmidt, C., Mcgonnell, I., Allen, S. Patel, K. (2008). The role of Wnt signalling in the development of somites and neural crest. Adv. Anat. Embryol. Cell Biol. 195, 1 64.
    • (2008) Adv. Anat. Embryol. Cell Biol. , vol.195 , pp. 1-64
    • Schmidt, C.1    McGonnell, I.2    Allen, S.3    Patel, K.4
  • 131
    • 34748812548 scopus 로고    scopus 로고
    • The Frizzled family of unconventional G-protein-coupled receptors
    • Schulte, G. Bryja, V. (2007). The Frizzled family of unconventional G-protein-coupled receptors. Trends Pharmacol. Sci. 28, 518 525.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 518-525
    • Schulte, G.1    Bryja, V.2
  • 132
    • 67449156114 scopus 로고    scopus 로고
    • Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration
    • Schwartz, A.L., Malgor, R., Dickerson, E., et al. (2009). Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration. Clin. Cancer Res. 15, 4114 4122.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 4114-4122
    • Schwartz, A.L.1    Malgor, R.2    Dickerson, E.3
  • 133
    • 0035049281 scopus 로고    scopus 로고
    • Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation
    • Sen, M., Chamorro, M., Reifert, J., Corr, M. Carson, D.A. (2001). Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation. Arthritis Rheum. 44, 772 781.
    • (2001) Arthritis Rheum. , vol.44 , pp. 772-781
    • Sen, M.1    Chamorro, M.2    Reifert, J.3    Corr, M.4    Carson, D.A.5
  • 134
    • 33644873387 scopus 로고    scopus 로고
    • Role of metalloproteinase-dependent EGF receptor activation in alpha-adrenoceptor-stimulated MAP kinase phosphorylation in GT1-7 neurons
    • Shah, B.H., Shah, F.B. Catt, K.J. (2006). Role of metalloproteinase- dependent EGF receptor activation in alpha-adrenoceptor-stimulated MAP kinase phosphorylation in GT1-7 neurons. J. Neurochem. 96, 520 532.
    • (2006) J. Neurochem. , vol.96 , pp. 520-532
    • Shah, B.H.1    Shah, F.B.2    Catt, K.J.3
  • 137
    • 53449090205 scopus 로고    scopus 로고
    • Gene silencing of β-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice
    • Takahashi, Y., Nishikawa, M., Suehara, T., Takiguchi, N. Takakura, Y. (2008). Gene silencing of β-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice. Int. J. Cancer 123, 2315 2320.
    • (2008) Int. J. Cancer , vol.123 , pp. 2315-2320
    • Takahashi, Y.1    Nishikawa, M.2    Suehara, T.3    Takiguchi, N.4    Takakura, Y.5
  • 138
    • 0034640443 scopus 로고    scopus 로고
    • Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a
    • Takeda, K., Yasumoto, K., Takada, R. et al. (2000). Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a. J. Biol. Chem. 275, 14013 14016.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14013-14016
    • Takeda, K.1    Yasumoto, K.2    Takada, R.3
  • 139
    • 0043063969 scopus 로고    scopus 로고
    • Down-regulation of Wnt-4 and up-regulation of Wnt-5a expression by epithelial-mesenchymal transition in human squamous carcinoma cells
    • Taki, M., Kamata, N., Yokoyama, K., Fujimoto, R., Tsutsumi, S. Nagayama, M. (2003). Down-regulation of Wnt-4 and up-regulation of Wnt-5a expression by epithelial-mesenchymal transition in human squamous carcinoma cells. Cancer Sci. 94, 593 597.
    • (2003) Cancer Sci. , vol.94 , pp. 593-597
    • Taki, M.1    Kamata, N.2    Yokoyama, K.3    Fujimoto, R.4    Tsutsumi, S.5    Nagayama, M.6
  • 140
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent β-catenin degradation
    • Topol, L., Jiang, X., Choi, H., Garrett-Beal, L., Carolan, P.J. Yang, Y. (2003). Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent β-catenin degradation. J. Cell Biol. 162, 899 908.
    • (2003) J. Cell Biol. , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 141
    • 26444460262 scopus 로고    scopus 로고
    • Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin
    • Ulrich, F., Krieg, M., Schotz, E.M. et al. (2005). Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev. Cell 9, 555 564.
    • (2005) Dev. Cell , vol.9 , pp. 555-564
    • Ulrich, F.1    Krieg, M.2    Schotz, E.M.3
  • 142
    • 0029071172 scopus 로고
    • Wnt4 affects morphogenesis when misexpressed in the zebrafish embryo
    • Ungar, A.R., Kelly, G.M. Moon, R.T. (1995). Wnt4 affects morphogenesis when misexpressed in the zebrafish embryo. Mech. Dev. 52, 153 164.
    • (1995) Mech. Dev. , vol.52 , pp. 153-164
    • Ungar, A.R.1    Kelly, G.M.2    Moon, R.T.3
  • 143
    • 43149104373 scopus 로고    scopus 로고
    • Molecular model of the Wnt protein binding site on the surface of dimeric CRD domain of the hFZD8 receptor
    • Voronkov, A.E., Baskin, I.I., Palyulin, V.A. Zefirov, N.S. (2008). Molecular model of the Wnt protein binding site on the surface of dimeric CRD domain of the hFZD8 receptor. Dokl. Biochem. Biophys. 419, 75 78.
    • (2008) Dokl. Biochem. Biophys. , vol.419 , pp. 75-78
    • Voronkov, A.E.1    Baskin, I.I.2    Palyulin, V.A.3    Zefirov, N.S.4
  • 144
    • 0036517835 scopus 로고    scopus 로고
    • Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays
    • Wai, D.H., Schaefer, K.L., Schramm, A. et al. (2002). Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays. Int. J. Oncol. 20, 441 451.
    • (2002) Int. J. Oncol. , vol.20 , pp. 441-451
    • Wai, D.H.1    Schaefer, K.L.2    Schramm, A.3
  • 145
    • 0024024316 scopus 로고
    • Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless
    • Wainwright, B.J., Scambler, P.J., Stanier, P. et al. (1988). Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless. EMBO J. 7, 1743 1748.
    • (1988) EMBO J. , vol.7 , pp. 1743-1748
    • Wainwright, B.J.1    Scambler, P.J.2    Stanier, P.3
  • 146
    • 21544439319 scopus 로고    scopus 로고
    • A Wnt-er wonderland-the complexity of Wnt signaling in melanoma
    • Weeraratna, A.T. (2005). A Wnt-er wonderland-the complexity of Wnt signaling in melanoma. Cancer Metastasis Rev. 24, 237 250.
    • (2005) Cancer Metastasis Rev. , vol.24 , pp. 237-250
    • Weeraratna, A.T.1
  • 148
    • 1842591177 scopus 로고    scopus 로고
    • Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome
    • Weeraratna, A.T., Becker, D., Carr, K.M., et al. (2004). Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome. Oncogene 23, 2264 2274.
    • (2004) Oncogene , vol.23 , pp. 2264-2274
    • Weeraratna, A.T.1    Becker, D.2    Carr, K.M.3
  • 149
    • 0034881357 scopus 로고    scopus 로고
    • Pan-trk inhibition decreases metastasis and enhances host survival in experimental models as a result of its selective induction of apoptosis of prostate cancer cells
    • Weeraratna, A.T., Dalrymple, S.L., Lamb, J.C., Denmeade, S.R., Miknyoczki, S., Dionne, C.A. Isaacs, J.T. (2001). Pan-trk inhibition decreases metastasis and enhances host survival in experimental models as a result of its selective induction of apoptosis of prostate cancer cells. Clin. Cancer Res. 7, 2237 2245.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2237-2245
    • Weeraratna, A.T.1    Dalrymple, S.L.2    Lamb, J.C.3    Denmeade, S.R.4    Miknyoczki, S.5    Dionne, C.A.6    Isaacs, J.T.7
  • 152
    • 0027205387 scopus 로고
    • Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases
    • Wilson, C., Goberdhan, D.C. Steller, H. (1993). Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases. Proc. Natl. Acad. Sci. USA 90, 7109 7113.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7109-7113
    • Wilson, C.1    Goberdhan, D.C.2    Steller, H.3
  • 153
    • 42349093195 scopus 로고    scopus 로고
    • Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
    • Witze, E.S., Litman, E.S., Argast, G.M., Moon, R.T. Ahn, N.G. (2008). Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. Science 320, 365 369.
    • (2008) Science , vol.320 , pp. 365-369
    • Witze, E.S.1    Litman, E.S.2    Argast, G.M.3    Moon, R.T.4    Ahn, N.G.5
  • 154
    • 0026630193 scopus 로고
    • Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family
    • Wolda, S.L. Moon, R.T. (1992). Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family. Oncogene 7, 1941 1947.
    • (1992) Oncogene , vol.7 , pp. 1941-1947
    • Wolda, S.L.1    Moon, R.T.2
  • 155
    • 3142710392 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of the APC gene in malignant melanoma
    • Worm, J., Christensen, C., Gronbaek, K., Tulchinsky, E. Guldberg, P. (2004). Genetic and epigenetic alterations of the APC gene in malignant melanoma. Oncogene 23, 5215 5226.
    • (2004) Oncogene , vol.23 , pp. 5215-5226
    • Worm, J.1    Christensen, C.2    Gronbaek, K.3    Tulchinsky, E.4    Guldberg, P.5
  • 156
    • 13544255576 scopus 로고    scopus 로고
    • Inhibition of CaMKII-mediated c-FLIP expression sensitizes malignant melanoma cells to TRAIL-induced apoptosis
    • Xiao, C., Yang, B.F., Song, J.H., Schulman, H., Li, L. Hao, C. (2005). Inhibition of CaMKII-mediated c-FLIP expression sensitizes malignant melanoma cells to TRAIL-induced apoptosis. Exp. Cell Res. 304, 244 255.
    • (2005) Exp. Cell Res. , vol.304 , pp. 244-255
    • Xiao, C.1    Yang, B.F.2    Song, J.H.3    Schulman, H.4    Li, L.5    Hao, C.6
  • 157
    • 42049101416 scopus 로고    scopus 로고
    • Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/β-catenin signaling in keratinocytes
    • Yamaguchi, Y., Passeron, T., Hoashi, T. et al. (2008). Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/β-catenin signaling in keratinocytes. FASEB J. 22, 1009 1020.
    • (2008) FASEB J. , vol.22 , pp. 1009-1020
    • Yamaguchi, Y.1    Passeron, T.2    Hoashi, T.3
  • 158
    • 0038744921 scopus 로고    scopus 로고
    • Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas
    • Yokoyama, K., Kamata, N., Fujimoto, R. et al. (2003). Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas. Int. J. Oncol. 22, 891 898.
    • (2003) Int. J. Oncol. , vol.22 , pp. 891-898
    • Yokoyama, K.1    Kamata, N.2    Fujimoto, R.3
  • 159
    • 3442894128 scopus 로고    scopus 로고
    • An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth
    • You, L., He, B., Xu, Z. et al. (2004). An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res. 64, 5385 5389.
    • (2004) Cancer Res. , vol.64 , pp. 5385-5389
    • You, L.1    He, B.2    Xu, Z.3
  • 160
    • 2342423023 scopus 로고    scopus 로고
    • The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway
    • Zilberberg, A., Yaniv, A. Gazit, A. (2004). The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway. J. Biol. Chem. 279, 17535 17542.
    • (2004) J. Biol. Chem. , vol.279 , pp. 17535-17542
    • Zilberberg, A.1    Yaniv, A.2    Gazit, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.