Synthetic lethality: General principles, utility and detection using genetic screens in human cells

FEBS Letters

Volumn 585, Issue 1, 2011, Pages 1-6

  Nijman, Sebastian M B ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Cancer; Genetic screens; Synthetic lethality

Indexed keywords

ARTICLE; CANCER THERAPY; CELL DEATH; COMPUTER ANALYSIS; CONCEPTUAL FRAMEWORK; DNA DAMAGE; DNA REPAIR; DRUG EFFICACY; DRUG MECHANISM; DRUG RESEARCH; DRUG SCREENING; FUNCTIONAL GENOMICS; GENE FUNCTION; GENE INTERACTION; GENE MAPPING; GENE SILENCING; GENE TARGETING; GENETIC CONSERVATION; GENOMIC INSTABILITY; HUMAN; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SYNTHETIC LETHALITY; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 78650890720     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.11.024     Document Type: Review

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