Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

PLoS Genetics

Volumn 4, Issue 11, 2008, Pages

  Yu, Lisa ^a   Lopez, Andres ^a,b   Anaflous, Abderrahmane ^c   El Bali, Brahim ^c   Hamal, Abdellah ^c   Ericson, Elke ^a,b   Heisler, Lawrence E ^a,b   McQuibban, Angus ^a   Giaever, Guri ^a,b   Nislow, Corey ^a,b   Boone, Charles ^a,b   Brown, Grant W ^a   Bellaoui, Mohammed ^c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c FACULTÉ DES SCIENCES   (Morocco)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYL 3 NITROSO IMIDAZO[1,2 A]PYRIMIDINE; CELL NUCLEUS DNA; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT;

ANIMAL CELL; ARTICLE; CELL CULTURE; DNA DAMAGE; DNA REPAIR; ELECTRON TRANSPORT; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MAMMAL CELL; MITOCHONDRION; MUTAGENESIS; NONHUMAN; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION; YEAST CELL; CHEMISTRY; DRUG EFFECT; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

ANTIFUNGAL AGENTS; CELLS, CULTURED; DNA DAMAGE; DNA REPAIR; HUMANS; MITOCHONDRIA; PYRIDINES; PYRIMIDINES; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

EID: 57149113921     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000284     Document Type: Article

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