메뉴 건너뛰기




Volumn 25, Issue 9, 2009, Pages 395-403

Robustness: mechanisms and consequences

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

EID: 69449106377     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2009.07.005     Document Type: Review
Times cited : (274)

References (93)
  • 1
    • 58549096683 scopus 로고    scopus 로고
    • Decanalization and the origin of complex disease
    • Gibson G. Decanalization and the origin of complex disease. Nat. Rev. Genet. 10 (2009) 134-140
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 134-140
    • Gibson, G.1
  • 3
    • 0035775725 scopus 로고    scopus 로고
    • A new approach to decoding life: Systems biology
    • Ideker T., et al. A new approach to decoding life: Systems biology. Annu. Rev. Genomics Hum. Genet. 2 (2001) 343-372
    • (2001) Annu. Rev. Genomics Hum. Genet. , vol.2 , pp. 343-372
    • Ideker, T.1
  • 5
    • 0001102269 scopus 로고
    • Genetic assimilation of an acquired character
    • Waddington C.H. Genetic assimilation of an acquired character. Evolution 7 (1953) 118-126
    • (1953) Evolution , vol.7 , pp. 118-126
    • Waddington, C.H.1
  • 6
    • 0002721909 scopus 로고
    • Genetic assimilation of the bithorax phenotype
    • Waddington C.H. Genetic assimilation of the bithorax phenotype. Evolution 10 (1956) 1-13
    • (1956) Evolution , vol.10 , pp. 1-13
    • Waddington, C.H.1
  • 7
    • 0001579865 scopus 로고
    • Canalization of development and genetic assimilation of acquired characters
    • Waddington C.H. Canalization of development and genetic assimilation of acquired characters. Nature 183 (1959) 1654-1655
    • (1959) Nature , vol.183 , pp. 1654-1655
    • Waddington, C.H.1
  • 8
    • 0032569851 scopus 로고    scopus 로고
    • Hsp90 as a capacitor for morphological evolution
    • Rutherford S.L., and Lindquist S. Hsp90 as a capacitor for morphological evolution. Nature 396 (1998) 336-342
    • (1998) Nature , vol.396 , pp. 336-342
    • Rutherford, S.L.1    Lindquist, S.2
  • 9
    • 0002498352 scopus 로고
    • Canalization - genetic and developmental aspects
    • Scharloo W. Canalization - genetic and developmental aspects. Annu. Rev. Ecol. Syst. 22 (1991) 65-93
    • (1991) Annu. Rev. Ecol. Syst. , vol.22 , pp. 65-93
    • Scharloo, W.1
  • 10
    • 56849091295 scopus 로고    scopus 로고
    • Network Hubs Buffer Environmental Variation in Saccharomyces cerevisiae
    • Levy S.F., and Siegal M.L. Network Hubs Buffer Environmental Variation in Saccharomyces cerevisiae. PLoS Biol. 6 (2008) e264
    • (2008) PLoS Biol. , vol.6
    • Levy, S.F.1    Siegal, M.L.2
  • 11
    • 0242349695 scopus 로고    scopus 로고
    • Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster
    • Dworkin I., et al. Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster. Curr. Biol. 13 (2003) 1888-1893
    • (2003) Curr. Biol. , vol.13 , pp. 1888-1893
    • Dworkin, I.1
  • 12
    • 0031932725 scopus 로고    scopus 로고
    • Naturally occurring genetic variation affects Drosophila photoreceptor determination
    • Polaczyk P.J., et al. Naturally occurring genetic variation affects Drosophila photoreceptor determination. Dev. Genes Evol. 207 (1998) 462-470
    • (1998) Dev. Genes Evol. , vol.207 , pp. 462-470
    • Polaczyk, P.J.1
  • 13
    • 65949100132 scopus 로고    scopus 로고
    • Network Features of the Mammalian Circadian Clock
    • Baggs J.E., et al. Network Features of the Mammalian Circadian Clock. PLoS Biol. 7 (2009) e52
    • (2009) PLoS Biol. , vol.7
    • Baggs, J.E.1
  • 15
    • 10744228524 scopus 로고    scopus 로고
    • Perspective: Evolution and detection of genetic robustness
    • de Visser J., et al. Perspective: Evolution and detection of genetic robustness. Evolution 57 (2003) 1959-1972
    • (2003) Evolution , vol.57 , pp. 1959-1972
    • de Visser, J.1
  • 16
    • 61449153907 scopus 로고    scopus 로고
    • Effects of Ploidy and Recombination on Evolution of Robustness in a Model of the Segment Polarity Network
    • Kim K.J., and Fernandes V.M. Effects of Ploidy and Recombination on Evolution of Robustness in a Model of the Segment Polarity Network. PLoS Comput. Biol. 5 (2009) e1000296
    • (2009) PLoS Comput. Biol. , vol.5
    • Kim, K.J.1    Fernandes, V.M.2
  • 17
    • 13944272337 scopus 로고    scopus 로고
    • The opportunity for canalization and the evolution of genetic networks
    • Proulx S.R., and Phillips P.C. The opportunity for canalization and the evolution of genetic networks. Am. Nat. 165 (2005) 147-162
    • (2005) Am. Nat. , vol.165 , pp. 147-162
    • Proulx, S.R.1    Phillips, P.C.2
  • 18
    • 0036678862 scopus 로고    scopus 로고
    • Waddington's canalization revisited: Developmental stability and evolution
    • Siegal M.L., and Bergman A. Waddington's canalization revisited: Developmental stability and evolution. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 10528-10532
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10528-10532
    • Siegal, M.L.1    Bergman, A.2
  • 19
    • 33745739006 scopus 로고    scopus 로고
    • Simulating the evolution of signal transduction pathways
    • Soyer O.S., et al. Simulating the evolution of signal transduction pathways. J. Theor. Biol. 241 (2006) 223-232
    • (2006) J. Theor. Biol. , vol.241 , pp. 223-232
    • Soyer, O.S.1
  • 20
    • 0033578335 scopus 로고    scopus 로고
    • Neutral evolution of mutational robustness
    • van Nimwegen E., et al. Neutral evolution of mutational robustness. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 9716-9720
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 9716-9720
    • van Nimwegen, E.1
  • 21
    • 0029661331 scopus 로고    scopus 로고
    • Does evolutionary plasticity evolve?
    • Wagner A. Does evolutionary plasticity evolve?. Evolution 50 (1996) 1008-1023
    • (1996) Evolution , vol.50 , pp. 1008-1023
    • Wagner, A.1
  • 22
    • 23844519964 scopus 로고    scopus 로고
    • Circuit topology and the evolution of robustness in two-gene circadian oscillators
    • Wagner A. Circuit topology and the evolution of robustness in two-gene circadian oscillators. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 11775-11780
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 11775-11780
    • Wagner, A.1
  • 23
    • 0034667684 scopus 로고    scopus 로고
    • Plasticity, evolvability, and modularity in RNA
    • Ancel L.W., and Fontana W. Plasticity, evolvability, and modularity in RNA. J. Exp. Zool. 288 (2000) 242-283
    • (2000) J. Exp. Zool. , vol.288 , pp. 242-283
    • Ancel, L.W.1    Fontana, W.2
  • 24
    • 62349105350 scopus 로고    scopus 로고
    • Congruent Evolution of Genetic and Environmental Robustness in Micro-RNA
    • Szöllo{combining double acute accent}si G.J., and Derényi I. Congruent Evolution of Genetic and Environmental Robustness in Micro-RNA. Mol. Biol. Evol. 26 (2009) 867-874
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 867-874
    • Szöllosi, G.J.1    Derényi, I.2
  • 25
    • 0030617955 scopus 로고    scopus 로고
    • A population genetic theory of canalization
    • Wagner G.P., et al. A population genetic theory of canalization. Evolution 51 (1997) 329-347
    • (1997) Evolution , vol.51 , pp. 329-347
    • Wagner, G.P.1
  • 26
    • 33644745138 scopus 로고    scopus 로고
    • Sexual reproduction selects for robustness and negative epistasis in artificial gene networks
    • Azevedo R.B.R., et al. Sexual reproduction selects for robustness and negative epistasis in artificial gene networks. Nature 440 (2006) 87-90
    • (2006) Nature , vol.440 , pp. 87-90
    • Azevedo, R.B.R.1
  • 27
    • 0025891893 scopus 로고
    • The role of RNA polymerase in transcriptional fidelity
    • Libby R.T., and Gallant J.A. The role of RNA polymerase in transcriptional fidelity. Mol. Microbiol. 5 (1991) 999-1004
    • (1991) Mol. Microbiol. , vol.5 , pp. 999-1004
    • Libby, R.T.1    Gallant, J.A.2
  • 28
    • 33845895536 scopus 로고    scopus 로고
    • The frequency of translational misreading errors in E. coli is largely determined by tRNA competition
    • Kramer E.B., and Farabaugh P.J. The frequency of translational misreading errors in E. coli is largely determined by tRNA competition. RNA-Publ. RNA Soc. 13 (2007) 87-96
    • (2007) RNA-Publ. RNA Soc. , vol.13 , pp. 87-96
    • Kramer, E.B.1    Farabaugh, P.J.2
  • 29
    • 65549084298 scopus 로고    scopus 로고
    • Potential role of phenotypic mutations in the evolution of protein expression and stability
    • Goldsmith M., and Tawfik D.S. Potential role of phenotypic mutations in the evolution of protein expression and stability. Proc. Natl. Acad. Sci. U. S. A. 106 (2009) 6197-6202
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 6197-6202
    • Goldsmith, M.1    Tawfik, D.S.2
  • 30
    • 0000359208 scopus 로고
    • Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity
    • Hopfield J.J. Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity. Proc. Natl. Acad. Sci. U. S. A. 71 (1974) 4135-4139
    • (1974) Proc. Natl. Acad. Sci. U. S. A. , vol.71 , pp. 4135-4139
    • Hopfield, J.J.1
  • 31
    • 33749392167 scopus 로고    scopus 로고
    • Effect of random and hub gene disruptions on environmental and mutational robustness in Escherichia coli
    • Cooper T., et al. Effect of random and hub gene disruptions on environmental and mutational robustness in Escherichia coli. BMC Genomics 7 (2006) 237
    • (2006) BMC Genomics , vol.7 , pp. 237
    • Cooper, T.1
  • 32
    • 0344824018 scopus 로고    scopus 로고
    • Quantitative trait symmetry independent of Hsp90 buffering: Distinct modes of genetic canalization and developmental stability
    • Milton C.C., et al. Quantitative trait symmetry independent of Hsp90 buffering: Distinct modes of genetic canalization and developmental stability. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 13396-13401
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 13396-13401
    • Milton, C.C.1
  • 33
    • 68949203710 scopus 로고    scopus 로고
    • Q&A: Cooperativity
    • Ferrell J. Q&A: Cooperativity. J. Biol 8 (2009) 53
    • (2009) J. Biol , vol.8 , pp. 53
    • Ferrell, J.1
  • 34
    • 39949083011 scopus 로고    scopus 로고
    • Drosophila growth and development in the absence of dMyc and dMnt
    • Pierce S.B., et al. Drosophila growth and development in the absence of dMyc and dMnt. Dev. Biol. 315 (2008) 303-316
    • (2008) Dev. Biol. , vol.315 , pp. 303-316
    • Pierce, S.B.1
  • 35
    • 58749109002 scopus 로고    scopus 로고
    • Circadian clocks can take a few transcriptional knocks
    • O'Neill J.S. Circadian clocks can take a few transcriptional knocks. EMBO J. 28 (2009) 84-85
    • (2009) EMBO J. , vol.28 , pp. 84-85
    • O'Neill, J.S.1
  • 36
    • 49649109812 scopus 로고    scopus 로고
    • Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade
    • Takahashi S., and Pryciak P.M. Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade. Curr. Biol. 18 (2008) 1184-1191
    • (2008) Curr. Biol. , vol.18 , pp. 1184-1191
    • Takahashi, S.1    Pryciak, P.M.2
  • 37
    • 41749107942 scopus 로고    scopus 로고
    • Stochasticity and cell fate
    • Losick R., and Desplan C. Stochasticity and cell fate. Science 320 (2008) 65-68
    • (2008) Science , vol.320 , pp. 65-68
    • Losick, R.1    Desplan, C.2
  • 38
    • 48249132857 scopus 로고    scopus 로고
    • Pervasive and Persistent Redundancy among Duplicated Genes in Yeast
    • Dean E.J., et al. Pervasive and Persistent Redundancy among Duplicated Genes in Yeast. PLoS Genet. 4 (2008) e1000113
    • (2008) PLoS Genet. , vol.4
    • Dean, E.J.1
  • 39
    • 15044353444 scopus 로고    scopus 로고
    • Transcription control reprogramming in genetic backup circuits
    • Kafri R., et al. Transcription control reprogramming in genetic backup circuits. Nat. Genet. 37 (2005) 295-299
    • (2005) Nat. Genet. , vol.37 , pp. 295-299
    • Kafri, R.1
  • 40
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon R., et al. Global variation in copy number in the human genome. Nature 444 (2006) 444-454
    • (2006) Nature , vol.444 , pp. 444-454
    • Redon, R.1
  • 41
    • 33947617347 scopus 로고    scopus 로고
    • Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss
    • Ihmels J., et al. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Mol. Syst. Biol. 3 (2007) 11
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 11
    • Ihmels, J.1
  • 42
    • 14344263352 scopus 로고    scopus 로고
    • Distributed robustness versus redundancy as causes of mutational robustness
    • Wagner A. Distributed robustness versus redundancy as causes of mutational robustness. BioEssays 27 (2005) 176-188
    • (2005) BioEssays , vol.27 , pp. 176-188
    • Wagner, A.1
  • 43
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: theory and experimental approaches
    • Alon U. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 8 (2007) 450-461
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 450-461
    • Alon, U.1
  • 44
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • Becskei A., and Serrano L. Engineering stability in gene networks by autoregulation. Nature 405 (2000) 590-593
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 45
    • 64249144494 scopus 로고    scopus 로고
    • A microRNA imparts robustness against environmental fluctuation during development
    • Li X., et al. A microRNA imparts robustness against environmental fluctuation during development. Cell 137 (2009) 273-282
    • (2009) Cell , vol.137 , pp. 273-282
    • Li, X.1
  • 46
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: Understanding the cell's functional organization
    • Barabási A.L., and Oltvai Z.N. Network biology: Understanding the cell's functional organization. Nat. Rev. Genet. 5 (2004) 101-113
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 101-113
    • Barabási, A.L.1    Oltvai, Z.N.2
  • 47
    • 33845637127 scopus 로고    scopus 로고
    • Functional and evolutionary inference in gene networks: does topology matter?
    • Siegal M.L., et al. Functional and evolutionary inference in gene networks: does topology matter?. Genetica 129 (2007) 83-103
    • (2007) Genetica , vol.129 , pp. 83-103
    • Siegal, M.L.1
  • 48
    • 0019869334 scopus 로고
    • The molecular basis of dominance
    • Kacser H., and Burns J.A. The molecular basis of dominance. Genetics 97 (1981) 639-666
    • (1981) Genetics , vol.97 , pp. 639-666
    • Kacser, H.1    Burns, J.A.2
  • 49
    • 13444306165 scopus 로고    scopus 로고
    • The landscape of genetic complexity across 5,700 gene expression traits in yeast
    • Brem R.B., and Kruglyak L. The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 1572-1577
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 1572-1577
    • Brem, R.B.1    Kruglyak, L.2
  • 50
    • 30044445643 scopus 로고    scopus 로고
    • High-dimensional and large-scale phenotyping of yeast mutants
    • Ohya Y., et al. High-dimensional and large-scale phenotyping of yeast mutants. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 19015-19020
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 19015-19020
    • Ohya, Y.1
  • 51
    • 43249103636 scopus 로고    scopus 로고
    • Cell-to-cell stochastic variation in gene expression is a complex genetic trait
    • Ansel J., et al. Cell-to-cell stochastic variation in gene expression is a complex genetic trait. PLoS Genet. 4 (2008) e1000049
    • (2008) PLoS Genet. , vol.4
    • Ansel, J.1
  • 52
    • 33847303495 scopus 로고    scopus 로고
    • Genetic complexity and quantitative trait loci mapping of yeast morphological traits
    • Nogami S., et al. Genetic complexity and quantitative trait loci mapping of yeast morphological traits. PLoS Genet. 3 (2007) e31
    • (2007) PLoS Genet. , vol.3
    • Nogami, S.1
  • 53
    • 59149100506 scopus 로고    scopus 로고
    • System-wide molecular evidence for phenotypic buffering in Arabidopsis
    • Fu J., et al. System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nat. Genet. 41 (2009) 166-167
    • (2009) Nat. Genet. , vol.41 , pp. 166-167
    • Fu, J.1
  • 54
    • 34548770425 scopus 로고    scopus 로고
    • Genetics of microenvironmental canalization in Arabidopsis thaliana
    • Hall M.C., et al. Genetics of microenvironmental canalization in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 13717-13722
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 13717-13722
    • Hall, M.C.1
  • 55
    • 55349132403 scopus 로고    scopus 로고
    • Plasticity and errors of a robust developmental system in different environments
    • Braendle C., and Félix M.-A. Plasticity and errors of a robust developmental system in different environments. Dev. Cell 15 (2008) 714-724
    • (2008) Dev. Cell , vol.15 , pp. 714-724
    • Braendle, C.1    Félix, M.-A.2
  • 56
    • 55749086858 scopus 로고    scopus 로고
    • Intraspecific evolution of the intercellular signaling network underlying a robust developmental system
    • Milloz J., et al. Intraspecific evolution of the intercellular signaling network underlying a robust developmental system. Genes Dev. 22 (2008) 3064-3075
    • (2008) Genes Dev. , vol.22 , pp. 3064-3075
    • Milloz, J.1
  • 57
    • 34249725570 scopus 로고    scopus 로고
    • Predictive modeling of signaling crosstalk during C. elegans vulval development
    • Fisher J., et al. Predictive modeling of signaling crosstalk during C. elegans vulval development. PLoS Comput. Biol. 3 (2007) e92
    • (2007) PLoS Comput. Biol. , vol.3
    • Fisher, J.1
  • 58
    • 0037686112 scopus 로고    scopus 로고
    • The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster
    • Albert R., and Othmer H.G. The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster. J. Theor. Biol. 223 (2003) 1-18
    • (2003) J. Theor. Biol. , vol.223 , pp. 1-18
    • Albert, R.1    Othmer, H.G.2
  • 59
    • 3142517462 scopus 로고    scopus 로고
    • Topology and robustness in the Drosophila segment polarity network
    • Ingolia N.T. Topology and robustness in the Drosophila segment polarity network. PLoS Biol. 2 (2004) e123
    • (2004) PLoS Biol. , vol.2
    • Ingolia, N.T.1
  • 60
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust developmental module
    • von Dassow G., et al. The segment polarity network is a robust developmental module. Nature 406 (2000) 188-192
    • (2000) Nature , vol.406 , pp. 188-192
    • von Dassow, G.1
  • 61
    • 65949084005 scopus 로고    scopus 로고
    • Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation
    • Manu, et al. Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation. PLoS Biol. 7 (2009) e49
    • (2009) PLoS Biol. , vol.7
    • Manu1
  • 62
    • 53349161901 scopus 로고    scopus 로고
    • Imaging individual mRNA molecules using multiple singly labeled probes
    • Raj A., et al. Imaging individual mRNA molecules using multiple singly labeled probes. Nat. Methods 5 (2008) 877-879
    • (2008) Nat. Methods , vol.5 , pp. 877-879
    • Raj, A.1
  • 63
    • 42049119399 scopus 로고    scopus 로고
    • Effects of the [PSI+] prion on rates of adaptation in yeast
    • Joseph S.B., and Kirkpatrick M. Effects of the [PSI+] prion on rates of adaptation in yeast. J. Evol. Biol. 21 (2008) 773-780
    • (2008) J. Evol. Biol. , vol.21 , pp. 773-780
    • Joseph, S.B.1    Kirkpatrick, M.2
  • 65
    • 0034727077 scopus 로고    scopus 로고
    • A yeast prion provides a mechanism for genetic variation and phenotypic diversity
    • True H.L., and Lindquist S.L. A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature 407 (2000) 477-483
    • (2000) Nature , vol.407 , pp. 477-483
    • True, H.L.1    Lindquist, S.L.2
  • 66
    • 0037030713 scopus 로고    scopus 로고
    • Hsp90 as a capacitor of phenotypic variation
    • Queitsch C., et al. Hsp90 as a capacitor of phenotypic variation. Nature 417 (2002) 618-624
    • (2002) Nature , vol.417 , pp. 618-624
    • Queitsch, C.1
  • 67
    • 1842782331 scopus 로고    scopus 로고
    • Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance
    • Sangster T.A., et al. Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance. BioEssays 26 (2004) 348-362
    • (2004) BioEssays , vol.26 , pp. 348-362
    • Sangster, T.A.1
  • 68
    • 0042154192 scopus 로고    scopus 로고
    • Evolutionary capacitance as a general feature of complex gene networks
    • Bergman A., and Siegal M.L. Evolutionary capacitance as a general feature of complex gene networks. Nature 424 (2003) 549-552
    • (2003) Nature , vol.424 , pp. 549-552
    • Bergman, A.1    Siegal, M.L.2
  • 69
    • 62549083590 scopus 로고    scopus 로고
    • Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression
    • Nevozhay D., et al. Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression. Proc. Natl. Acad. Sci. U. S. A. 106 (2009) 5123-5128
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 5123-5128
    • Nevozhay, D.1
  • 70
    • 33746525415 scopus 로고    scopus 로고
    • Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways
    • Lehner B., et al. Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat. Genet. 38 (2006) 896-903
    • (2006) Nat. Genet. , vol.38 , pp. 896-903
    • Lehner, B.1
  • 71
    • 34447546660 scopus 로고    scopus 로고
    • The distribution of fitness effects of new mutations
    • Eyre-Walker A., and Keightley P.D. The distribution of fitness effects of new mutations. Nat. Rev. Genet. 8 (2007) 610-618
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 610-618
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 72
    • 33645232390 scopus 로고    scopus 로고
    • Cryptic genetic variation is enriched for potential adaptations
    • Masel J. Cryptic genetic variation is enriched for potential adaptations. Genetics 172 (2006) 1985-1991
    • (2006) Genetics , vol.172 , pp. 1985-1991
    • Masel, J.1
  • 73
    • 0031927740 scopus 로고    scopus 로고
    • Canalization, genetic assimilation and preadaptation: A quantitative genetic model
    • Eshel I., and Matessi C. Canalization, genetic assimilation and preadaptation: A quantitative genetic model. Genetics 149 (1998) 2119-2133
    • (1998) Genetics , vol.149 , pp. 2119-2133
    • Eshel, I.1    Matessi, C.2
  • 74
    • 33645811495 scopus 로고    scopus 로고
    • Protein stability promotes evolvability
    • Bloom J.D., et al. Protein stability promotes evolvability. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 5869-5874
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 5869-5874
    • Bloom, J.D.1
  • 75
    • 50049135016 scopus 로고    scopus 로고
    • Robustness promotes evolvability of thermotolerance in an RNA virus
    • McBride R.C., et al. Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Evol. Biol. 8 (2008) 231
    • (2008) BMC Evol. Biol. , vol.8 , pp. 231
    • McBride, R.C.1
  • 76
    • 45149112698 scopus 로고    scopus 로고
    • The look-ahead effect of phenotypic mutations
    • Whitehead D.J., et al. The look-ahead effect of phenotypic mutations. Biol. Direct 3 (2008) 18
    • (2008) Biol. Direct , vol.3 , pp. 18
    • Whitehead, D.J.1
  • 77
    • 67651230677 scopus 로고    scopus 로고
    • +], even with realistic rates of yeast sex
    • +], even with realistic rates of yeast sex. PLoS Genet. 5 (2009) e1000517
    • (2009) PLoS Genet. , vol.5
    • Griswold, C.K.1    Masel, J.2
  • 78
    • 36348992094 scopus 로고    scopus 로고
    • Robustness and evolvability: a paradox resolved
    • Wagner A. Robustness and evolvability: a paradox resolved. Proc. R. Soc. B. Biol. Sci. 275 (2008) 91-100
    • (2008) Proc. R. Soc. B. Biol. Sci. , vol.275 , pp. 91-100
    • Wagner, A.1
  • 79
    • 65649128164 scopus 로고    scopus 로고
    • Evolutionary consequences of cryptic genetic variation
    • McGuigan K., and Sgrò C.M. Evolutionary consequences of cryptic genetic variation. Trends Ecol. Evol. 24 (2009) 305-311
    • (2009) Trends Ecol. Evol. , vol.24 , pp. 305-311
    • McGuigan, K.1    Sgrò, C.M.2
  • 80
    • 35349007441 scopus 로고    scopus 로고
    • The evolution of bet-hedging adaptations to rare scenarios
    • King O., and Masel J. The evolution of bet-hedging adaptations to rare scenarios. Theor. Pop. Biol. 72 (2007) 560-575
    • (2007) Theor. Pop. Biol. , vol.72 , pp. 560-575
    • King, O.1    Masel, J.2
  • 81
    • 34547684827 scopus 로고    scopus 로고
    • Rate of adaptive peak shifts with partial genetic robustness
    • Kim Y. Rate of adaptive peak shifts with partial genetic robustness. Evolution 61 (2007) 1847-1856
    • (2007) Evolution , vol.61 , pp. 1847-1856
    • Kim, Y.1
  • 82
    • 37249030834 scopus 로고    scopus 로고
    • Is evolvability evolvable?
    • Pigliucci M. Is evolvability evolvable?. Nat. Rev. Genet. 9 (2008) 75-82
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 75-82
    • Pigliucci, M.1
  • 83
    • 33748994704 scopus 로고    scopus 로고
    • Stochastic mRNA synthesis in mammalian cells
    • Raj A., et al. Stochastic mRNA synthesis in mammalian cells. PLoS Biol. 4 (2006) e309
    • (2006) PLoS Biol. , vol.4
    • Raj, A.1
  • 84
    • 19544379881 scopus 로고    scopus 로고
    • Stochasticity in gene expression: from theories to phenotypes
    • Kærn M., et al. Stochasticity in gene expression: from theories to phenotypes. Nat. Rev. Genet. 6 (2005) 451-464
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 451-464
    • Kærn, M.1
  • 85
    • 51049091861 scopus 로고    scopus 로고
    • Epigenetic control of polyamines by the prion [PSI+]
    • Namy O., et al. Epigenetic control of polyamines by the prion [PSI+]. Nat. Cell. Biol. 10 (2008) 1069-1075
    • (2008) Nat. Cell. Biol. , vol.10 , pp. 1069-1075
    • Namy, O.1
  • 86
    • 22544436364 scopus 로고    scopus 로고
    • Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation
    • Wilson M.A., et al. Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 10244-10249
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 10244-10249
    • Wilson, M.A.1
  • 87
    • 33947390044 scopus 로고    scopus 로고
    • Evolution of budding yeast prion-determinant sequences across diverse fungi
    • Harrison L.B., et al. Evolution of budding yeast prion-determinant sequences across diverse fungi. J. Mol. Biol. 368 (2007) 273-282
    • (2007) J. Mol. Biol. , vol.368 , pp. 273-282
    • Harrison, L.B.1
  • 88
    • 62549142749 scopus 로고    scopus 로고
    • The strength of selection against the yeast prion [PSI+]
    • Masel J., and Griswold C.K. The strength of selection against the yeast prion [PSI+]. Genetics 181 (2009) 1057-1063
    • (2009) Genetics , vol.181 , pp. 1057-1063
    • Masel, J.1    Griswold, C.K.2
  • 89
    • 23344432509 scopus 로고    scopus 로고
    • Evolutionary capacitance may be favored by natural selection
    • Masel J. Evolutionary capacitance may be favored by natural selection. Genetics 170 (2005) 1359-1371
    • (2005) Genetics , vol.170 , pp. 1359-1371
    • Masel, J.1
  • 90
    • 33846215623 scopus 로고    scopus 로고
    • The loss of adaptive plasticity during long periods of environmental stasis
    • Masel J., et al. The loss of adaptive plasticity during long periods of environmental stasis. Am. Nat. 169 (2007) 38-46
    • (2007) Am. Nat. , vol.169 , pp. 38-46
    • Masel, J.1
  • 91
    • 33846840904 scopus 로고    scopus 로고
    • The conversion of 3′ UTRs into coding regions
    • Giacomelli M.G., et al. The conversion of 3′ UTRs into coding regions. Mol. Biol. Evol. 24 (2007) 457-464
    • (2007) Mol. Biol. Evol. , vol.24 , pp. 457-464
    • Giacomelli, M.G.1
  • 92
    • 0001735834 scopus 로고
    • Some aspects of evolution
    • Goldschmidt R. Some aspects of evolution. Science 78 (1933) 539-547
    • (1933) Science , vol.78 , pp. 539-547
    • Goldschmidt, R.1
  • 93
    • 4544235083 scopus 로고    scopus 로고
    • Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits
    • True H.L., et al. Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature 431 (2004) 184-187
    • (2004) Nature , vol.431 , pp. 184-187
    • True, H.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.