-
1
-
-
21544473568
-
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity
-
Kirkland D, Aardema M, Henderson L, Muller L. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity. Mutat Res 2005, 584:1-256.
-
(2005)
Mutat Res
, vol.584
, pp. 1-256
-
-
Kirkland, D.1
Aardema, M.2
Henderson, L.3
Muller, L.4
-
2
-
-
44349170697
-
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity
-
10.1016/j.taap.2008.01.037, 18346771
-
Elferink MG, Olinga P, Draaisma AL, Merema MT, Bauerschmidt S, Polman J, et al. Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity. Toxicol Appl Pharmacol 2008, 229:300-309. 10.1016/j.taap.2008.01.037, 18346771.
-
(2008)
Toxicol Appl Pharmacol
, vol.229
, pp. 300-309
-
-
Elferink, M.G.1
Olinga, P.2
Draaisma, A.L.3
Merema, M.T.4
Bauerschmidt, S.5
Polman, J.6
-
3
-
-
27144534545
-
Toxicity assessment of industrial chemicals and airborne contaminants: transition from in vivo to in vitro test methods: a review
-
10.1080/08958370500225240, 16195213
-
Bakand S, Winder C, Khalil C, Hayes A. Toxicity assessment of industrial chemicals and airborne contaminants: transition from in vivo to in vitro test methods: a review. Inhal Toxicol 2005, 17:775-787. 10.1080/08958370500225240, 16195213.
-
(2005)
Inhal Toxicol
, vol.17
, pp. 775-787
-
-
Bakand, S.1
Winder, C.2
Khalil, C.3
Hayes, A.4
-
4
-
-
34247362027
-
Methods and goals for the use of in vitro and in vivo chemosensitivity testing
-
10.1007/BF02686104, 17435285
-
Blumenthal RD, Goldenberg DM. Methods and goals for the use of in vitro and in vivo chemosensitivity testing. Mol Biotechnol 2007, 35:185-197. 10.1007/BF02686104, 17435285.
-
(2007)
Mol Biotechnol
, vol.35
, pp. 185-197
-
-
Blumenthal, R.D.1
Goldenberg, D.M.2
-
5
-
-
33748796347
-
Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti)estrogenic activity of chemical substances
-
10.1016/j.aquatox.2006.07.013, 16950525
-
Navas JM, Segner H. Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti)estrogenic activity of chemical substances. Aquat Toxicol 2006, 80:1-22. 10.1016/j.aquatox.2006.07.013, 16950525.
-
(2006)
Aquat Toxicol
, vol.80
, pp. 1-22
-
-
Navas, J.M.1
Segner, H.2
-
6
-
-
0021256345
-
Genotoxic activity of nitroaromatic explosives and related compounds in Salmonella typhimurium
-
10.1016/0165-1218(84)90054-5, 6377057
-
Whong WZ, Edwards GS. Genotoxic activity of nitroaromatic explosives and related compounds in Salmonella typhimurium. Mutat Res 1984, 136:209-215. 10.1016/0165-1218(84)90054-5, 6377057.
-
(1984)
Mutat Res
, vol.136
, pp. 209-215
-
-
Whong, W.Z.1
Edwards, G.S.2
-
7
-
-
33749621418
-
Gene expression profiles in fathead minnow exposed to 2,4-DNT: correlation with toxicity in mammals
-
10.1093/toxsci/kfl080, 16917068
-
Wintz H, Yoo LJ, Loguinov A, Wu YY, Steevens JA, Holland RD, et al. Gene expression profiles in fathead minnow exposed to 2,4-DNT: correlation with toxicity in mammals. Toxicol Sci 2006, 94:71-82. 10.1093/toxsci/kfl080, 16917068.
-
(2006)
Toxicol Sci
, vol.94
, pp. 71-82
-
-
Wintz, H.1
Yoo, L.J.2
Loguinov, A.3
Wu, Y.Y.4
Steevens, J.A.5
Holland, R.D.6
-
8
-
-
77957183419
-
Toxic interactions of the munitions compounds TNT and RDX in F344 rats
-
10.1016/0272-0590(90)90062-O, 2227162
-
Levine BS, Furedi EM, Gordon DE, Barkley JJ, Lish PM. Toxic interactions of the munitions compounds TNT and RDX in F344 rats. Fundam Appl Toxicol 1990, 15:373-380. 10.1016/0272-0590(90)90062-O, 2227162.
-
(1990)
Fundam Appl Toxicol
, vol.15
, pp. 373-380
-
-
Levine, B.S.1
Furedi, E.M.2
Gordon, D.E.3
Barkley, J.J.4
Lish, P.M.5
-
9
-
-
34147167636
-
Comparison of biomarkers in workers exposed to 2,4,6-trinitrotoluene
-
10.1080/13547500600807012, 17438651
-
Sabbioni G, Sepai O, Norppa H, Yan H, Hirvonen A, Zheng Y, et al. Comparison of biomarkers in workers exposed to 2,4,6-trinitrotoluene. Biomarkers 2007, 12:21-37. 10.1080/13547500600807012, 17438651.
-
(2007)
Biomarkers
, vol.12
, pp. 21-37
-
-
Sabbioni, G.1
Sepai, O.2
Norppa, H.3
Yan, H.4
Hirvonen, A.5
Zheng, Y.6
-
10
-
-
22844443877
-
Hemoglobin adducts, urinary metabolites and health effects in 2,4,6-trinitrotoluene exposed workers
-
10.1093/carcin/bgi078, 15817613
-
Sabbioni G, Liu YY, Yan H, Sepai O. Hemoglobin adducts, urinary metabolites and health effects in 2,4,6-trinitrotoluene exposed workers. Carcinogenesis 2005, 26:1272-1279. 10.1093/carcin/bgi078, 15817613.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1272-1279
-
-
Sabbioni, G.1
Liu, Y.Y.2
Yan, H.3
Sepai, O.4
-
11
-
-
0030580977
-
Determination of hemoglobin adducts in workers exposed to 2,4, 6-trinitrotoluene
-
10.1016/0378-4347(96)00083-7, 8844416
-
Sabbioni G, Wei J, Liu YY. Determination of hemoglobin adducts in workers exposed to 2,4, 6-trinitrotoluene. J Chromatogr B Biomed Appl 1996, 682:243-248. 10.1016/0378-4347(96)00083-7, 8844416.
-
(1996)
J Chromatogr B Biomed Appl
, vol.682
, pp. 243-248
-
-
Sabbioni, G.1
Wei, J.2
Liu, Y.Y.3
-
12
-
-
36849047287
-
Toxicogenomic analysis provides new insights into molecular mechanisms of the sublethal toxicity of 2,4,6-trinitrotoluene in Eisenia fetida
-
10.1021/es0716352, 18186358
-
Gong P, Guan X, Inouye LS, Pirooznia M, Indest KJ, Athow RS, et al. Toxicogenomic analysis provides new insights into molecular mechanisms of the sublethal toxicity of 2,4,6-trinitrotoluene in Eisenia fetida. Environ Sci Technol 2007, 41:8195-8202. 10.1021/es0716352, 18186358.
-
(2007)
Environ Sci Technol
, vol.41
, pp. 8195-8202
-
-
Gong, P.1
Guan, X.2
Inouye, L.S.3
Pirooznia, M.4
Indest, K.J.5
Athow, R.S.6
-
13
-
-
57549102935
-
Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases
-
10.1111/j.1365-313X.2008.03653.x, 18702669
-
Gandia-Herrero F, Lorenz A, Larson T, Graham IA, Bowles DJ, Rylott EL, et al. Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases. Plant J 2008, 56:963-974. 10.1111/j.1365-313X.2008.03653.x, 18702669.
-
(2008)
Plant J
, vol.56
, pp. 963-974
-
-
Gandia-Herrero, F.1
Lorenz, A.2
Larson, T.3
Graham, I.A.4
Bowles, D.J.5
Rylott, E.L.6
-
14
-
-
34247497135
-
Hazard characterization and identification of a former ammunition site using microarrays, bioassays, and chemical analysis
-
10.1897/06-285R.1, 17447547
-
Eisentraeger A, Reifferscheid G, Dardenne F, Blust R, Schofer A. Hazard characterization and identification of a former ammunition site using microarrays, bioassays, and chemical analysis. Environ Toxicol Chem 2007, 26:634-646. 10.1897/06-285R.1, 17447547.
-
(2007)
Environ Toxicol Chem
, vol.26
, pp. 634-646
-
-
Eisentraeger, A.1
Reifferscheid, G.2
Dardenne, F.3
Blust, R.4
Schofer, A.5
-
15
-
-
0034604636
-
Zeta-crystallin catalyzes the reductive activation of 2,4,6-trinitrotoluene to generate reactive oxygen species: a proposed mechanism for the induction of cataracts
-
10.1016/S0014-5793(00)01841-X, 10930585
-
Kumagai Y, Wakayama T, Lib S, Shinohara A, Iwamatsu A, Sun G, et al. Zeta-crystallin catalyzes the reductive activation of 2,4,6-trinitrotoluene to generate reactive oxygen species: a proposed mechanism for the induction of cataracts. FEBS Lett 2000, 478:295-298. 10.1016/S0014-5793(00)01841-X, 10930585.
-
(2000)
FEBS Lett
, vol.478
, pp. 295-298
-
-
Kumagai, Y.1
Wakayama, T.2
Lib, S.3
Shinohara, A.4
Iwamatsu, A.5
Sun, G.6
-
16
-
-
33947371709
-
Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine
-
10.1186/1471-2105-7-S4-S22, 1780121, 17217515
-
Perkins EJ, Bao W, Guan X, Ang CY, Wolfinger RD, Chu TM, et al. Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine. BMC Bioinformatics 2006, 7(Suppl 4):S22. 10.1186/1471-2105-7-S4-S22, 1780121, 17217515.
-
(2006)
BMC Bioinformatics
, vol.7
, Issue.SUPPL 4
-
-
Perkins, E.J.1
Bao, W.2
Guan, X.3
Ang, C.Y.4
Wolfinger, R.D.5
Chu, T.M.6
-
17
-
-
0141541760
-
DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase
-
10.1091/mbc.E03-03-0168, 206994, 14517313
-
Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, et al. DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase. Mol Biol Cell 2003, 14:3989-4002. 10.1091/mbc.E03-03-0168, 206994, 14517313.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 3989-4002
-
-
Chow, J.P.1
Siu, W.Y.2
Fung, T.K.3
Chan, W.M.4
Lau, A.5
Arooz, T.6
-
18
-
-
0142135133
-
Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints
-
10.1074/jbc.M306683200, 12912980
-
Chow JP, Siu WY, Ho HT, Ma KH, Ho CC, Poon RY. Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints. J Biol Chem 2003, 278:40815-40828. 10.1074/jbc.M306683200, 12912980.
-
(2003)
J Biol Chem
, vol.278
, pp. 40815-40828
-
-
Chow, J.P.1
Siu, W.Y.2
Ho, H.T.3
Ma, K.H.4
Ho, C.C.5
Poon, R.Y.6
-
19
-
-
0030910680
-
Isolation and characterization of a pituitary tumor-transforming gene (PTTG)
-
10.1210/me.11.4.433, 9092795
-
Pei L, Melmed S. Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol Endocrinol 1997, 11:433-441. 10.1210/me.11.4.433, 9092795.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 433-441
-
-
Pei, L.1
Melmed, S.2
-
20
-
-
0033575347
-
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
-
10.1126/science.285.5426.418, 10411507
-
Zou H, McGarry TJ, Bernal T, Kirschner MW. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science 1999, 285:418-422. 10.1126/science.285.5426.418, 10411507.
-
(1999)
Science
, vol.285
, pp. 418-422
-
-
Zou, H.1
McGarry, T.J.2
Bernal, T.3
Kirschner, M.W.4
-
21
-
-
70349659021
-
Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice
-
10.1096/fj.08-127852, 19546305
-
Kaafarani I, Fernandez-Sauze S, Berenguer C, Chinot O, Delfino C, Dussert C, et al. Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice. FASEB J 2009, 23:3424-3435. 10.1096/fj.08-127852, 19546305.
-
(2009)
FASEB J
, vol.23
, pp. 3424-3435
-
-
Kaafarani, I.1
Fernandez-Sauze, S.2
Berenguer, C.3
Chinot, O.4
Delfino, C.5
Dussert, C.6
-
22
-
-
0035445710
-
Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
-
10.1093/nar/29.17.3595, 55878, 11522829
-
Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ. Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. Nucleic Acids Res 2001, 29:3595-3602. 10.1093/nar/29.17.3595, 55878, 11522829.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 3595-3602
-
-
Park, J.W.1
Voss, P.G.2
Grabski, S.3
Wang, J.L.4
Patterson, R.J.5
-
23
-
-
0842281645
-
Cell death: critical control points
-
10.1016/S0092-8674(04)00046-7, 14744432
-
Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004, 116:205-219. 10.1016/S0092-8674(04)00046-7, 14744432.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
24
-
-
67650569135
-
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
-
10.1016/j.cell.2009.04.060, 19632177
-
Bersell K, Arab S, Haring B, Kuhn B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 2009, 138:257-270. 10.1016/j.cell.2009.04.060, 19632177.
-
(2009)
Cell
, vol.138
, pp. 257-270
-
-
Bersell, K.1
Arab, S.2
Haring, B.3
Kuhn, B.4
-
25
-
-
34247863773
-
The neuregulin-I/ErbB signaling system in development and disease
-
full_text, 17432114
-
Britsch S. The neuregulin-I/ErbB signaling system in development and disease. Adv Anat Embryol Cell Biol 2007, 190:1-65. full_text, 17432114.
-
(2007)
Adv Anat Embryol Cell Biol
, vol.190
, pp. 1-65
-
-
Britsch, S.1
-
26
-
-
0030911331
-
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
-
10.1038/387509a0, 9168114
-
Chang H, Riese DJ, Gilbert W, Stern DF, McMahan UJ. Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature 1997, 387:509-512. 10.1038/387509a0, 9168114.
-
(1997)
Nature
, vol.387
, pp. 509-512
-
-
Chang, H.1
Riese, D.J.2
Gilbert, W.3
Stern, D.F.4
McMahan, U.J.5
-
27
-
-
0034713444
-
Roles of PPARs in health and disease
-
10.1038/35013000, 10839530
-
Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000, 405:421-424. 10.1038/35013000, 10839530.
-
(2000)
Nature
, vol.405
, pp. 421-424
-
-
Kersten, S.1
Desvergne, B.2
Wahli, W.3
-
28
-
-
0032588487
-
PPARgamma, the ultimate thrifty gene
-
10.1007/s001250051268, 10447513
-
Auwerx J. PPARgamma, the ultimate thrifty gene. Diabetologia 1999, 42:1033-1049. 10.1007/s001250051268, 10447513.
-
(1999)
Diabetologia
, vol.42
, pp. 1033-1049
-
-
Auwerx, J.1
-
29
-
-
29144486781
-
Retinoid × receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes
-
Rasooly R, Schuster GU, Gregg JP, Xiao JH, Chandraratna RA, Stephensen CB. Retinoid × receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes. J Immunol 2005, 175:7916-7929.
-
(2005)
J Immunol
, vol.175
, pp. 7916-7929
-
-
Rasooly, R.1
Schuster, G.U.2
Gregg, J.P.3
Xiao, J.H.4
Chandraratna, R.A.5
Stephensen, C.B.6
-
30
-
-
0032789259
-
Cytotoxic and genotoxic effects of energetic compounds on bacterial and mammalian cells in vitro
-
Lachance B, Robidoux PY, Hawari J, Ampleman G, Thiboutot S, Sunahara GI. Cytotoxic and genotoxic effects of energetic compounds on bacterial and mammalian cells in vitro. Mutat Res 1999, 444:25-39.
-
(1999)
Mutat Res
, vol.444
, pp. 25-39
-
-
Lachance, B.1
Robidoux, P.Y.2
Hawari, J.3
Ampleman, G.4
Thiboutot, S.5
Sunahara, G.I.6
-
31
-
-
0027389277
-
Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes
-
1132219, 8435060
-
Padgham CR, Paine AJ. Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes. Biochem J 1993, 289(Pt 3):621-624. 1132219, 8435060.
-
(1993)
Biochem J
, vol.289
, Issue.PART 3
, pp. 621-624
-
-
Padgham, C.R.1
Paine, A.J.2
-
32
-
-
0037156460
-
Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment
-
10.1016/S0048-9697(01)01016-6, 12049406
-
Hahn ME. Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment. Sci Total Environ 2002, 289:49-69. 10.1016/S0048-9697(01)01016-6, 12049406.
-
(2002)
Sci Total Environ
, vol.289
, pp. 49-69
-
-
Hahn, M.E.1
-
33
-
-
0037184858
-
Transgenic models in xenobiotic metabolism and toxicology
-
10.1016/S0300-483X(02)00288-3, 12505317
-
Gonzalez FJ. Transgenic models in xenobiotic metabolism and toxicology. Toxicology 2002, 181-182:237-239. 10.1016/S0300-483X(02)00288-3, 12505317.
-
(2002)
Toxicology
, vol.181-182
, pp. 237-239
-
-
Gonzalez, F.J.1
-
34
-
-
0036707694
-
Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss)
-
Hawkins SA, Billiard SM, Tabash SP, Brown RS, Hodson PV. Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss). Environ Toxicol Chem 2002, 21:1845-1853.
-
(2002)
Environ Toxicol Chem
, vol.21
, pp. 1845-1853
-
-
Hawkins, S.A.1
Billiard, S.M.2
Tabash, S.P.3
Brown, R.S.4
Hodson, P.V.5
-
35
-
-
0034121761
-
A repressive cross-regulation between catalytic and promoter activities of the CYP1A1 and CYP2E1 genes: role of H(2)O(2)
-
Morel Y, de W, Barouki R. A repressive cross-regulation between catalytic and promoter activities of the CYP1A1 and CYP2E1 genes: role of H(2)O(2). Mol Pharmacol 2000, 57:1158-1164.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 1158-1164
-
-
Morel, Y.1
de, W.2
Barouki, R.3
-
36
-
-
20544460373
-
Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity
-
10.1093/toxsci/kfi162, 15800033
-
Boverhof DR, Burgoon LD, Tashiro C, Chittim B, Harkema JR, Jump DB, et al. Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity. Toxicol Sci 2005, 85:1048-1063. 10.1093/toxsci/kfi162, 15800033.
-
(2005)
Toxicol Sci
, vol.85
, pp. 1048-1063
-
-
Boverhof, D.R.1
Burgoon, L.D.2
Tashiro, C.3
Chittim, B.4
Harkema, J.R.5
Jump, D.B.6
-
37
-
-
45549092690
-
Pregnane × receptor protects HepG2 cells from BaP-induced DNA damage
-
10.1093/toxsci/kfn058, 18381355
-
Naspinski C, Gu X, Zhou GD, Mertens-Talcott SU, Donnelly KC, Tian Y. Pregnane × receptor protects HepG2 cells from BaP-induced DNA damage. Toxicol Sci 2008, 104:67-73. 10.1093/toxsci/kfn058, 18381355.
-
(2008)
Toxicol Sci
, vol.104
, pp. 67-73
-
-
Naspinski, C.1
Gu, X.2
Zhou, G.D.3
Mertens-Talcott, S.U.4
Donnelly, K.C.5
Tian, Y.6
-
38
-
-
47549096446
-
Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3
-
10.1021/tx7004458, 18416522
-
Bodreddigari S, Jones LK, Egner PA, Groopman JD, Sutter CH, Roebuck BD, et al. Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3. Chem Res Toxicol 2008, 21:1134-1142. 10.1021/tx7004458, 18416522.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 1134-1142
-
-
Bodreddigari, S.1
Jones, L.K.2
Egner, P.A.3
Groopman, J.D.4
Sutter, C.H.5
Roebuck, B.D.6
-
39
-
-
34548476945
-
Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice
-
10.1074/jbc.M702076200, 2253645, 17567582
-
Lassen N, Bateman JB, Estey T, Kuszak JR, Nees DW, Piatigorsky J, et al. Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice. J Biol Chem 2007, 282:25668-25676. 10.1074/jbc.M702076200, 2253645, 17567582.
-
(2007)
J Biol Chem
, vol.282
, pp. 25668-25676
-
-
Lassen, N.1
Bateman, J.B.2
Estey, T.3
Kuszak, J.R.4
Nees, D.W.5
Piatigorsky, J.6
-
40
-
-
0020464384
-
DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation
-
10.1016/0003-9861(82)90202-8, 6285828
-
Lind C, Hochstein P, Ernster L. DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation. Arch Biochem Biophys 1982, 216:178-185. 10.1016/0003-9861(82)90202-8, 6285828.
-
(1982)
Arch Biochem Biophys
, vol.216
, pp. 178-185
-
-
Lind, C.1
Hochstein, P.2
Ernster, L.3
-
41
-
-
0020440918
-
The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells
-
Thor H, Smith MT, Hartzell P, Bellomo G, Jewell SA, Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. J Biol Chem 1982, 257:12419-12425.
-
(1982)
J Biol Chem
, vol.257
, pp. 12419-12425
-
-
Thor, H.1
Smith, M.T.2
Hartzell, P.3
Bellomo, G.4
Jewell, S.A.5
Orrenius, S.6
-
42
-
-
0013080216
-
Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems
-
10.1074/jbc.M211981200, 12529318
-
Anwar A, Dehn D, Siegel D, Kepa JK, Tang LJ, Pietenpol JA, et al. Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems. J Biol Chem 2003, 278:10368-10373. 10.1074/jbc.M211981200, 12529318.
-
(2003)
J Biol Chem
, vol.278
, pp. 10368-10373
-
-
Anwar, A.1
Dehn, D.2
Siegel, D.3
Kepa, J.K.4
Tang, L.J.5
Pietenpol, J.A.6
-
43
-
-
51849142786
-
Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
-
10.1093/toxsci/kfn136, 2527642, 18622027
-
Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure. Toxicol Sci 2008, 105:351-359. 10.1093/toxsci/kfn136, 2527642, 18622027.
-
(2008)
Toxicol Sci
, vol.105
, pp. 351-359
-
-
Keating, A.F.1
Rajapaksa, K.S.2
Sipes, I.G.3
Hoyer, P.B.4
-
44
-
-
41449094548
-
Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes
-
10.1074/jbc.R700044200, 18073217
-
Harris SJ, Parry RV, Westwick J, Ward SG. Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes. J Biol Chem 2008, 283:2465-2469. 10.1074/jbc.R700044200, 18073217.
-
(2008)
J Biol Chem
, vol.283
, pp. 2465-2469
-
-
Harris, S.J.1
Parry, R.V.2
Westwick, J.3
Ward, S.G.4
-
45
-
-
65449137548
-
Genetic variance in the adiponutrin gene family and childhood obesity
-
10.1371/journal.pone.0005327, 2669125, 19390624
-
Johansson LE, Johansson LM, Danielsson P, Norgren S, Johansson S, Marcus C, et al. Genetic variance in the adiponutrin gene family and childhood obesity. PLoS One 2009, 4:e5327. 10.1371/journal.pone.0005327, 2669125, 19390624.
-
(2009)
PLoS One
, vol.4
-
-
Johansson, L.E.1
Johansson, L.M.2
Danielsson, P.3
Norgren, S.4
Johansson, S.5
Marcus, C.6
-
46
-
-
23344437782
-
Contributions of Ca2+ to galectin-1-induced exposure of phosphatidylserine on activated neutrophils
-
10.1074/jbc.M414140200, 15929990
-
Karmakar S, Cummings RD, McEver RP. Contributions of Ca2+ to galectin-1-induced exposure of phosphatidylserine on activated neutrophils. J Biol Chem 2005, 280:28623-28631. 10.1074/jbc.M414140200, 15929990.
-
(2005)
J Biol Chem
, vol.280
, pp. 28623-28631
-
-
Karmakar, S.1
Cummings, R.D.2
McEver, R.P.3
-
47
-
-
67650756609
-
17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes
-
10.1677/JOE-09-0021, 19380458
-
Tagawa N, Yuda R, Kubota S, Wakabayashi M, Yamaguchi Y, Kiyonaga D, et al. 17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes. J Endocrinol 2009, 202:131-139. 10.1677/JOE-09-0021, 19380458.
-
(2009)
J Endocrinol
, vol.202
, pp. 131-139
-
-
Tagawa, N.1
Yuda, R.2
Kubota, S.3
Wakabayashi, M.4
Yamaguchi, Y.5
Kiyonaga, D.6
-
48
-
-
43849098723
-
A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis
-
10.1677/JOE-08-0050, 2315694, 18434359
-
Bujalska IJ, Gathercole LL, Tomlinson JW, Darimont C, Ermolieff J, Fanjul AN, et al. A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. J Endocrinol 2008, 197:297-307. 10.1677/JOE-08-0050, 2315694, 18434359.
-
(2008)
J Endocrinol
, vol.197
, pp. 297-307
-
-
Bujalska, I.J.1
Gathercole, L.L.2
Tomlinson, J.W.3
Darimont, C.4
Ermolieff, J.5
Fanjul, A.N.6
-
49
-
-
77955464209
-
From raw materials to validated system: The construction of a genomic library and microarray to interpret systemic perturbations in Northern bobwhite
-
Rawat A, Gust KA, Deng Y, Garcia-Reyero N, Quinn MJ, Johnson MS, et al. From raw materials to validated system: The construction of a genomic library and microarray to interpret systemic perturbations in Northern bobwhite. Physiol Genomics 2010, 7;42(2):219-35.
-
(2010)
Physiol Genomics
, vol.7-42
, Issue.2
, pp. 219-235
-
-
Rawat, A.1
Gust, K.A.2
Deng, Y.3
Garcia-Reyero, N.4
Quinn, M.J.5
Johnson, M.S.6
-
50
-
-
69549086437
-
Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration
-
10.1084/jem.20082074, 2737164, 19687226
-
Grundler R, Brault L, Gasser C, Bullock AN, Dechow T, Woetzel S, et al. Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. J Exp Med 2009, 206:1957-1970. 10.1084/jem.20082074, 2737164, 19687226.
-
(2009)
J Exp Med
, vol.206
, pp. 1957-1970
-
-
Grundler, R.1
Brault, L.2
Gasser, C.3
Bullock, A.N.4
Dechow, T.5
Woetzel, S.6
-
51
-
-
20044368218
-
The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
-
10.1084/jem.20041924, 2213063, 15728238
-
Mandal M, Borowski C, Palomero T, Ferrando AA, Oberdoerffer P, Meng F, et al. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med 2005, 201:603-614. 10.1084/jem.20041924, 2213063, 15728238.
-
(2005)
J Exp Med
, vol.201
, pp. 603-614
-
-
Mandal, M.1
Borowski, C.2
Palomero, T.3
Ferrando, A.A.4
Oberdoerffer, P.5
Meng, F.6
-
52
-
-
34247190780
-
Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice
-
10.1161/CIRCULATIONAHA.107.688523, 17404153
-
Kitamoto S, Sukhova GK, Sun J, Yang M, Libby P, Love V, et al. Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice. Circulation 2007, 115:2065-2075. 10.1161/CIRCULATIONAHA.107.688523, 17404153.
-
(2007)
Circulation
, vol.115
, pp. 2065-2075
-
-
Kitamoto, S.1
Sukhova, G.K.2
Sun, J.3
Yang, M.4
Libby, P.5
Love, V.6
-
53
-
-
0033010661
-
Genetic analysis of B cell antigen receptor signaling
-
10.1146/annurev.immunol.17.1.555, 10358768
-
Kurosaki T. Genetic analysis of B cell antigen receptor signaling. Annu Rev Immunol 1999, 17:555-592. 10.1146/annurev.immunol.17.1.555, 10358768.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 555-592
-
-
Kurosaki, T.1
-
54
-
-
33745847565
-
The scaffold protein Cybr is required for cytokine-modulated trafficking of leukocytes in vivo
-
10.1128/MCB.02473-05, 1592701, 16809763
-
Coppola V, Barrick CA, Bobisse S, Rodriguez-Galan MC, Pivetta M, Reynolds D, et al. The scaffold protein Cybr is required for cytokine-modulated trafficking of leukocytes in vivo. Mol Cell Biol 2006, 26:5249-5258. 10.1128/MCB.02473-05, 1592701, 16809763.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5249-5258
-
-
Coppola, V.1
Barrick, C.A.2
Bobisse, S.3
Rodriguez-Galan, M.C.4
Pivetta, M.5
Reynolds, D.6
-
55
-
-
0027509501
-
Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis
-
413175, 8428594
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G. Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J 1993, 12:53-63. 413175, 8428594.
-
(1993)
EMBO J
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
56
-
-
0034928035
-
The mitotic roles of Polo-like kinase
-
Donaldson MM, Tavares AA, Hagan IM, Nigg EA, Glover DM. The mitotic roles of Polo-like kinase. J Cell Sci 2001, 114:2357-2358.
-
(2001)
J Cell Sci
, vol.114
, pp. 2357-2358
-
-
Donaldson, M.M.1
Tavares, A.A.2
Hagan, I.M.3
Nigg, E.A.4
Glover, D.M.5
-
57
-
-
0035858876
-
Metaphase arrest with centromere separation in polo mutants of Drosophila
-
10.1083/jcb.153.4.663, 2192380, 11352929
-
Donaldson MM, Tavares AA, Ohkura H, Deak P, Glover DM. Metaphase arrest with centromere separation in polo mutants of Drosophila. J Cell Biol 2001, 153:663-676. 10.1083/jcb.153.4.663, 2192380, 11352929.
-
(2001)
J Cell Biol
, vol.153
, pp. 663-676
-
-
Donaldson, M.M.1
Tavares, A.A.2
Ohkura, H.3
Deak, P.4
Glover, D.M.5
-
58
-
-
0036650070
-
Evaluation of tissue and cellular biomarkers to assess 2,4,6-trinitrotoluene (TNT) exposure in earthworms: effects-based assessment in laboratory studies using Eisenia andrei
-
10.1080/13547500210127327, 12171758
-
Robidoux PY, Svendsen C, Sarrazin M, Hawari J, Thiboutot S, Ampleman G, et al. Evaluation of tissue and cellular biomarkers to assess 2,4,6-trinitrotoluene (TNT) exposure in earthworms: effects-based assessment in laboratory studies using Eisenia andrei. Biomarkers 2002, 7:306-321. 10.1080/13547500210127327, 12171758.
-
(2002)
Biomarkers
, vol.7
, pp. 306-321
-
-
Robidoux, P.Y.1
Svendsen, C.2
Sarrazin, M.3
Hawari, J.4
Thiboutot, S.5
Ampleman, G.6
-
59
-
-
12944324229
-
Assessment of a 2,4,6-trinitrotoluene-contaminated site using Aporrectodea rosea and Eisenia andrei in mesocosms
-
10.1007/s00244-004-0217-7, 15657806
-
Robidoux PY, Svendsen C, Sarrazin M, Thiboutot S, Ampleman G, Hawari J, et al. Assessment of a 2,4,6-trinitrotoluene-contaminated site using Aporrectodea rosea and Eisenia andrei in mesocosms. Arch Environ Contam Toxicol 2005, 48:56-67. 10.1007/s00244-004-0217-7, 15657806.
-
(2005)
Arch Environ Contam Toxicol
, vol.48
, pp. 56-67
-
-
Robidoux, P.Y.1
Svendsen, C.2
Sarrazin, M.3
Thiboutot, S.4
Ampleman, G.5
Hawari, J.6
-
60
-
-
44449123703
-
Transcriptomic analysis of RDX and TNT interactive sublethal effects in the earthworm Eisenia fetida
-
10.1186/1471-2164-9-S1-S15, 2386057, 18366604
-
Gong P, Guan X, Inouye LS, Deng Y, Pirooznia M, Perkins EJ. Transcriptomic analysis of RDX and TNT interactive sublethal effects in the earthworm Eisenia fetida. BMC Genomics 2008, 9(Suppl 1):S15. 10.1186/1471-2164-9-S1-S15, 2386057, 18366604.
-
(2008)
BMC Genomics
, vol.9
, Issue.SUPPL 1
-
-
Gong, P.1
Guan, X.2
Inouye, L.S.3
Deng, Y.4
Pirooznia, M.5
Perkins, E.J.6
-
61
-
-
65749113675
-
Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses
-
10.1016/j.taap.2009.04.005, 2696203, 19371757
-
Zhang Q, Pi J, Woods CG, Andersen ME. Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses. Toxicol Appl Pharmacol 2009, 237:345-356. 10.1016/j.taap.2009.04.005, 2696203, 19371757.
-
(2009)
Toxicol Appl Pharmacol
, vol.237
, pp. 345-356
-
-
Zhang, Q.1
Pi, J.2
Woods, C.G.3
Andersen, M.E.4
-
62
-
-
23344439806
-
Structural and biochemical analysis reveal pirins to possess quercetinase activity
-
10.1074/jbc.M501034200, 15951572
-
Adams M, Jia Z. Structural and biochemical analysis reveal pirins to possess quercetinase activity. J Biol Chem 2005, 280:28675-28682. 10.1074/jbc.M501034200, 15951572.
-
(2005)
J Biol Chem
, vol.280
, pp. 28675-28682
-
-
Adams, M.1
Jia, Z.2
-
63
-
-
59049100782
-
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative
-
10.1016/j.cbi.2008.10.040, 2896744, 19027726
-
Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, et al. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chem Biol Interact 2009, 178:94-98. 10.1016/j.cbi.2008.10.040, 2896744, 19027726.
-
(2009)
Chem Biol Interact
, vol.178
, pp. 94-98
-
-
Persson, B.1
Kallberg, Y.2
Bray, J.E.3
Bruford, E.4
Dellaporta, S.L.5
Favia, A.D.6
-
64
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
10.1074/jbc.M211898200, 12506115
-
Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J Biol Chem 2003, 278:8135-8145. 10.1074/jbc.M211898200, 12506115.
-
(2003)
J Biol Chem
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
65
-
-
0003633755
-
-
National Academy Press, Washington D.C, National Research Council
-
National Research Council Guide for the care and use of laboratory animals 1996, National Academy Press, Washington D.C, National Research Council.
-
(1996)
Guide for the care and use of laboratory animals
-
-
-
66
-
-
33846400424
-
Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles
-
10.1371/journal.pbio.0050008, 1764438, 17214507
-
Faith JJ, Hayete B, Thaden JT, Mogno I, Wierzbowski J, Cottarel G, et al. Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol 2007, 5:e8. 10.1371/journal.pbio.0050008, 1764438, 17214507.
-
(2007)
PLoS Biol
, vol.5
-
-
Faith, J.J.1
Hayete, B.2
Thaden, J.T.3
Mogno, I.4
Wierzbowski, J.5
Cottarel, G.6
-
67
-
-
50949117527
-
Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stress
-
2516606, 18769717
-
Taylor RC, cquaah-Mensah G, Singhal M, Malhotra D, Biswal S. Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stress. PLoS Comput Biol 2008, 4:e1000166. 2516606, 18769717.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Taylor, R.C.1
cquaah-Mensah, G.2
Singhal, M.3
Malhotra, D.4
Biswal, S.5
-
68
-
-
54949102064
-
Integrating expression data with domain interaction networks
-
10.1093/bioinformatics/btn437, 2572699, 18710874
-
Emig D, Cline MS, Lengauer T, Albrecht M. Integrating expression data with domain interaction networks. Bioinformatics 2008, 24:2546-2548. 10.1093/bioinformatics/btn437, 2572699, 18710874.
-
(2008)
Bioinformatics
, vol.24
, pp. 2546-2548
-
-
Emig, D.1
Cline, M.S.2
Lengauer, T.3
Albrecht, M.4
-
69
-
-
38449101120
-
Integration of biological networks and gene expression data using Cytoscape
-
10.1038/nprot.2007.324, 17947979
-
Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, et al. Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2007, 2:2366-2382. 10.1038/nprot.2007.324, 17947979.
-
(2007)
Nat Protoc
, vol.2
, pp. 2366-2382
-
-
Cline, M.S.1
Smoot, M.2
Cerami, E.3
Kuchinsky, A.4
Landys, N.5
Workman, C.6
|