Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice

Circulation

Volumn 115, Issue 15, 2007, Pages 2065-2075

  Kitamoto, Shiro ^a   Sukhova, Galina K ^a   Sun, Jiusong ^a   Yang, Min ^a   Libby, Peter ^a   Love, Victoria ^a   Duramad, Paurene ^a   Sun, Chongxiu ^a   Zhang, Yadong ^a   Yang, Xiuwei ^b   Peters, Christoph ^c   Shi, Guo Ping ^a,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

^d Cardiovascular Medicine   (United States)

Author keywords

Atherosclerosis; Cathepsin L; Collagen; Elastin; Metalloproteinases; Receptors, LDL; Remodeling

Indexed keywords

CATHEPSIN L; COLLAGEN; CYSTEINE PROTEINASE; ELASTIN; LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEIN INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BASEMENT MEMBRANE; CD4+ T LYMPHOCYTE; CELL MIGRATION; CHEMICAL LABELING; CONTROLLED STUDY; CROSS BREEDING; DIET; DISEASE ASSOCIATION; ENZYME ACTIVE SITE; IN VITRO STUDY; KNOCKOUT MOUSE; LEUKOCYTE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SMOOTH MUSCLE FIBER; T LYMPHOCYTE;

ANIMALS; AORTA, THORACIC; ATHEROSCLEROSIS; CATHEPSINS; CELLS, CULTURED; CHEMOTAXIS; CYSTEINE ENDOPEPTIDASES; DIET, ATHEROGENIC; DISEASE PROGRESSION; ENDOTHELIAL CELLS; LIPIDS; MALE; MICE; MICE, KNOCKOUT; MONOCYTES; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, LDL;

EID: 34247190780     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.688523     Document Type: Article

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