Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3

Chemical Research in Toxicology

Volumn 21, Issue 5, 2008, Pages 1134-1142

  Bodreddigari, Sridevi ^a   Jones, Laundette Knight ^b   Egner, Patricia A ^b   Groopman, John D ^b   Sutter, Carrie Hayes ^a   Roebuck, Bill D ^c   Guengerich, F Peter ^d   Kensler, Thomas W ^b   Sutter, Thomas R ^a  

^a UNIVERSITY OF MEMPHIS   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; AFLATOXIN B1 ALDEHYDE REDUCTASE; ALDEHYDE DERIVATIVE; ALDEHYDE REDUCTASE; ALDOKETOREDUCTASE 7A1; ALDOKETOREDUCTASE 7A2; ALDOKETOREDUCTASE 7A3; CELL PROTEIN; CYTOCHROME P450 1A2; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; EXPERIMENTAL RAT; FRACTIONATION; GENETIC ENGINEERING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; LYMPHOBLASTOID CELL LINE; MICROSOME; MITOCHONDRION; NONHUMAN; NUCLEUS ACCUMBENS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REDUCTION; ANIMAL; CELL LINE; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RAT;

RATTUS;

AFLATOXIN B1; ALDEHYDE REDUCTASE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LIVER; MOLECULAR STRUCTURE; RATS; RNA, MESSENGER;

EID: 47549096446     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx7004458     Document Type: Article

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