Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage

Toxicological Sciences

Volumn 104, Issue 1, 2008, Pages 67-73

  Naspinski, Christine ^a   Gu, Xinsheng ^a   Zhou, Guo Dong ^b   Mertens Talcott, Susanne U ^a   Donnelly, Kirby C ^a,b   Tian, Yanan ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Benzo a pyrene; DNA adducts; HepG2; Pregnane X receptor

Indexed keywords

BENZO[A]PYRENE; BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450 1A2; GLUCURONOSYLTRANSFERASE 1A6; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE A2; GLUTATHIONE TRANSFERASE M1; MESSENGER RNA; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON; PREGNANE X RECEPTOR; XENOBIOTIC AGENT;

ANIMAL CELL CULTURE; ARTICLE; CARCINOGEN DNA INTERACTION; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; ENZYME ACTIVITY; EXCRETION; EXPOSURE; GENETIC REGULATION; GENETIC TRANSFECTION; GENOTOXICITY; HUMAN; HUMAN CELL; LIVER CELL; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BENZO(A)PYRENE; CARCINOGENS; CELL LINE, TUMOR; DNA ADDUCTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; HUMANS; RECEPTORS, STEROID; RNA, MESSENGER; TRANSFECTION;

EID: 45549092690     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn058     Document Type: Article

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