Activation of the ancestral polarity regulator protein kinase Cζ at the immunological synapse drives polarization of Th cell secretory machinery toward APCs

Journal of Immunology

Volumn 185, Issue 5, 2010, Pages 2887-2894

  Bertrand, Florie ^a   Esquerré, Michael ^a,d   Petit, Anne Elisabeth ^a   Rodrigues, Magda ^a   Duchez, Sophie ^a   Delon, Jérôme ^a,c   Valitutti, Salvatore ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c INSTITUT COCHIN   (France)

^d Genticel SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 12P70; PROTEIN KINASE C ZETA; T LYMPHOCYTE RECEPTOR; ISOENZYME; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE C;

ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME PHOSPHORYLATION; HELPER CELL; HUMAN; IMMUNOLOGICAL SYNAPSE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL POLARITY; COCULTURE; ENZYME ACTIVATION; ENZYMOLOGY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SECRETION;

ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL POLARITY; CELLS, CULTURED; COCULTURE TECHNIQUES; DENDRITIC CELLS; ENZYME ACTIVATION; HUMANS; IMMUNOLOGICAL SYNAPSES; INTERFERON-GAMMA; ISOENZYMES; LYMPHOCYTE ACTIVATION; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION;

EID: 78049386951     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000739     Document Type: Article

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