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Volumn 12, Issue 2, 2000, Pages 161-170

Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

EID: 0034288890     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1074-7613(00)80169-7     Document Type: Article
Times cited : (104)

References (42)
  • 3
    • 0031297664 scopus 로고    scopus 로고
    • A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice
    • Andre, P., Boretto, J., Hueber, A.O., Regnier-Vigouroux, A., Gorvel, J.P., Ferrier, P., and Chavrier, P. (1997). A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice. J. Immunol. 159, 5253-5263.
    • (1997) J. Immunol. , vol.159 , pp. 5253-5263
    • Andre, P.1    Boretto, J.2    Hueber, A.O.3    Regnier-Vigouroux, A.4    Gorvel, J.P.5    Ferrier, P.6    Chavrier, P.7
  • 4
    • 0032492852 scopus 로고    scopus 로고
    • Receptor clustering as a cellular mechanism to control sensitivity
    • Bray, D., Levin, M.D., and Morton-Firth, C.J. (1998). Receptor clustering as a cellular mechanism to control sensitivity. Nature 393, 85-88.
    • (1998) Nature , vol.393 , pp. 85-88
    • Bray, D.1    Levin, M.D.2    Morton-Firth, C.J.3
  • 5
    • 0031037183 scopus 로고    scopus 로고
    • Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells
    • Cai, Z., Kishimoto, H., Brunmark, A., Jackson, M.R., Peterson, P.A., and Sprent, J. (1997). Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J. Exp. Med. 185, 641-651.
    • (1997) J. Exp. Med. , vol.185 , pp. 641-651
    • Cai, Z.1    Kishimoto, H.2    Brunmark, A.3    Jackson, M.R.4    Peterson, P.A.5    Sprent, J.6
  • 6
    • 0029874657 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction pathways
    • Cantrell, D. (1996). T cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14, 259-274.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 259-274
    • Cantrell, D.1
  • 7
    • 0024150991 scopus 로고
    • The T cell receptor/CD3 complex: A dynamic protein ensemble
    • Clevers, H., Alarcon, B., Wileman, T., and Terhorst, C. (1988). The T cell receptor/CD3 complex: A dynamic protein ensemble. Annu. Rev. Immunol. 6, 629-662.
    • (1988) Annu. Rev. Immunol. , vol.6 , pp. 629-662
    • Clevers, H.1    Alarcon, B.2    Wileman, T.3    Terhorst, C.4
  • 8
    • 0028179026 scopus 로고
    • CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor
    • Dietrich, J., Hou, X., Wegener, A.M., and Geisler, C. (1994). CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor. EMBO J. 13, 2156-2166.
    • (1994) EMBO J. , vol.13 , pp. 2156-2166
    • Dietrich, J.1    Hou, X.2    Wegener, A.M.3    Geisler, C.4
  • 9
    • 0033199986 scopus 로고    scopus 로고
    • Cross-antagonism of a T cell clone expressing two distinct T cell receptors
    • Dittel, B.N., Stefanova, I., Germain, R.N., and Janeway, C.A., Jr. (1999). Cross-antagonism of a T cell clone expressing two distinct T cell receptors. Immunity 11, 289-298.
    • (1999) Immunity , vol.11 , pp. 289-298
    • Dittel, B.N.1    Stefanova, I.2    Germain, R.N.3    Janeway C.A., Jr.4
  • 10
    • 0029122018 scopus 로고
    • Evidence for multivalent structure of T-cell antigen receptor complex
    • Exley, M., Wileman, T., Mueller, B., and Terhorst, C. (1995). Evidence for multivalent structure of T-cell antigen receptor complex. Mol. Immunol. 32, 829-839.
    • (1995) Mol. Immunol. , vol.32 , pp. 829-839
    • Exley, M.1    Wileman, T.2    Mueller, B.3    Terhorst, C.4
  • 12
    • 0025295281 scopus 로고
    • Structural mutations of the T cell receptor zeta chain and its role in T cell activation
    • Frank, S.J., Niklinska, B.B., Orloff, D.G., Mercep, M., Ashwell, J.D., and Klausner, R.D. (1990). Structural mutations of the T cell receptor zeta chain and its role in T cell activation. Science 249, 174-177.
    • (1990) Science , vol.249 , pp. 174-177
    • Frank, S.J.1    Niklinska, B.B.2    Orloff, D.G.3    Mercep, M.4    Ashwell, J.D.5    Klausner, R.D.6
  • 13
    • 0033563137 scopus 로고    scopus 로고
    • The TCR zeta-chain immunoreceptor tyrosine-based activation motifs are sufficient for the activation and differentiation of primary T lymphocytes
    • Geiger, T.L., Leitenberg, D., and Flavell, R.A. (1999). The TCR zeta-chain immunoreceptor tyrosine-based activation motifs are sufficient for the activation and differentiation of primary T lymphocytes. J. Immunol. 162, 5931-5939.
    • (1999) J. Immunol. , vol.162 , pp. 5931-5939
    • Geiger, T.L.1    Leitenberg, D.2    Flavell, R.A.3
  • 14
    • 0023429078 scopus 로고
    • Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor
    • Goldsmith, M.A., and Weiss, A. (1987). Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc. Natl. Acad. Sci. USA 84, 6879-6883.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6879-6883
    • Goldsmith, M.A.1    Weiss, A.2
  • 15
    • 0026064305 scopus 로고
    • The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways
    • Irving, B.A., and Weiss, A. (1991). The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell 64, 891-901.
    • (1991) Cell , vol.64 , pp. 891-901
    • Irving, B.A.1    Weiss, A.2
  • 16
    • 0023724619 scopus 로고
    • Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines
    • Lechler, R.I., Bal, V., Rothbard, J.B., Germain, R.N., Sekaly, R., Long, E.O., and Lamb, J. (1988). Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines. J. Immunol. 141, 3003-3009.
    • (1988) J. Immunol. , vol.141 , pp. 3003-3009
    • Lechler, R.I.1    Bal, V.2    Rothbard, J.B.3    Germain, R.N.4    Sekaly, R.5    Long, E.O.6    Lamb, J.7
  • 17
    • 0025998529 scopus 로고
    • T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins
    • Letourneur, F., and Klausner, R.D. (1991). T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins. Proc. Natl. Acad. Sci. USA 88, 8905-8909.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8905-8909
    • Letourneur, F.1    Klausner, R.D.2
  • 18
    • 0026547056 scopus 로고
    • Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon
    • Letourneur, F., and Klausner, R.D. (1992). Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon. Science 255, 79-82.
    • (1992) Science , vol.255 , pp. 79-82
    • Letourneur, F.1    Klausner, R.D.2
  • 19
    • 0028290315 scopus 로고
    • Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution
    • Luton, F., Buferne, M., Davoust, J., Schmitt-Verhulst, A.M., and Boyer, C. (1994). Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution. J. Immunol. 153, 63-72.
    • (1994) J. Immunol. , vol.153 , pp. 63-72
    • Luton, F.1    Buferne, M.2    Davoust, J.3    Schmitt-Verhulst, A.M.4    Boyer, C.5
  • 20
    • 0031114123 scopus 로고    scopus 로고
    • Tyrosine and serine protein kinase activities associated with ligand-induced internalized TCR/CD3 complexes
    • Luton, F., Legendre, V., Gorvel, J.P., Schmitt-Verhulst, A.M., and Boyer, C. (1997). Tyrosine and serine protein kinase activities associated with ligand-induced internalized TCR/CD3 complexes. J. Immunol. 158, 3140-3147.
    • (1997) J. Immunol. , vol.158 , pp. 3140-3147
    • Luton, F.1    Legendre, V.2    Gorvel, J.P.3    Schmitt-Verhulst, A.M.4    Boyer, C.5
  • 21
    • 0027310116 scopus 로고
    • Transmembrane signaling through the T-cell-receptor-CD3 complex
    • Malissen, B., and Schmitt-Verhulst, A.M. (1993). Transmembrane signaling through the T-cell-receptor-CD3 complex. Curr. Opin. Immunol. 5, 324-333.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 324-333
    • Malissen, B.1    Schmitt-Verhulst, A.M.2
  • 22
    • 0031688113 scopus 로고    scopus 로고
    • Transient alteration of T cell fine specificity by a strong primary stimulus correlates with T cell receptor down-regulation
    • Martin, S., and Bevan, M.J. (1998). Transient alteration of T cell fine specificity by a strong primary stimulus correlates with T cell receptor down-regulation. Eur. J. Immunol. 28, 2991-3002.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2991-3002
    • Martin, S.1    Bevan, M.J.2
  • 23
    • 0031571327 scopus 로고    scopus 로고
    • Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors
    • Niedergang, F., Dautry-Varsat, A., and Alcover, A. (1997). Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors. J. Immunol. 159, 1703-1710.
    • (1997) J. Immunol. , vol.159 , pp. 1703-1710
    • Niedergang, F.1    Dautry-Varsat, A.2    Alcover, A.3
  • 24
    • 0032403582 scopus 로고    scopus 로고
    • Cooperative activation of TCRs by enterotoxin superantigens
    • Niedergang, F., Dautry-Varsat, A., and Alcover, A. (1998). Cooperative activation of TCRs by enterotoxin superantigens. J. Immunol. 161, 6054-6058.
    • (1998) J. Immunol. , vol.161 , pp. 6054-6058
    • Niedergang, F.1    Dautry-Varsat, A.2    Alcover, A.3
  • 25
    • 0030943398 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction
    • Qian, D., and Weiss, A. (1997). T cell antigen receptor signal transduction. Curr. Opin. Cell Biol. 9, 205-212.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 205-212
    • Qian, D.1    Weiss, A.2
  • 26
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M. (1989). Antigen receptor tail clue. Nature 338, 383-384.
    • (1989) Nature , vol.338 , pp. 383-384
    • Reth, M.1
  • 27
    • 0030016487 scopus 로고    scopus 로고
    • How T cells count
    • Rothenberg, E.V. (1996). How T cells count. Science 273, 78-79.
    • (1996) Science , vol.273 , pp. 78-79
    • Rothenberg, E.V.1
  • 28
    • 0026782498 scopus 로고
    • Transmembrane helical interactions: Zeta chain dimerization and functional association with the T cell antigen receptor
    • Rutledge, T., Cosson, P., Manolios, N., Bonifacino, J.S., and Klausner, R.D. (1992). Transmembrane helical interactions: Zeta chain dimerization and functional association with the T cell antigen receptor. EMBO J. 11, 3245-3254.
    • (1992) EMBO J. , vol.11 , pp. 3245-3254
    • Rutledge, T.1    Cosson, P.2    Manolios, N.3    Bonifacino, J.S.4    Klausner, R.D.5
  • 29
    • 0030847844 scopus 로고    scopus 로고
    • Agonist-induced T cell receptor down-regulation: Molecular requirements and dissociation from T cell activation
    • Salio, M., Valitutti, S., and Lanzavecchia, A. (1997). Agonist-induced T cell receptor down-regulation: Molecular requirements and dissociation from T cell activation. Eur. J. Immunol. 27, 1769-1773.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1769-1773
    • Salio, M.1    Valitutti, S.2    Lanzavecchia, A.3
  • 30
    • 0031583841 scopus 로고    scopus 로고
    • Megalomicin inhibits HIV-1 replication and interferes with gp160 processing
    • San José, E., Munoz-Fernandez, M.A., and Alarcon, B. (1997). Megalomicin inhibits HIV-1 replication and interferes with gp160 processing. Virology 239, 303-314.
    • (1997) Virology , vol.239 , pp. 303-314
    • San José, E.1    Munoz-Fernandez, M.A.2    Alarcon, B.3
  • 31
    • 2642612819 scopus 로고    scopus 로고
    • Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model
    • San José, E., Sahuquillo, A.G., Bragado, R., and Alarcon, B. (1998). Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model. Eur. J. Immunol. 28, 12-21.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 12-21
    • San José, E.1    Sahuquillo, A.G.2    Bragado, R.3    Alarcon, B.4
  • 33
    • 0030222298 scopus 로고    scopus 로고
    • Receptor signaling and the regulation of endocytic membrane transport
    • Seaman, M.N., Burd, C.G., and Emr, S.D. (1996). Receptor signaling and the regulation of endocytic membrane transport. Curr. Opin. Cell Biol. 8, 549-556.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 549-556
    • Seaman, M.N.1    Burd, C.G.2    Emr, S.D.3
  • 34
    • 0028986925 scopus 로고
    • CD3 epsilon and CD3 zeta cytoplasmic domains can independently generate signals for T cell development and function
    • Shinkai, Y., Ma, A., Cheng, H.L., and Alt, F.W. (1995). CD3 epsilon and CD3 zeta cytoplasmic domains can independently generate signals for T cell development and function. Immunity 2, 401-411.
    • (1995) Immunity , vol.2 , pp. 401-411
    • Shinkai, Y.1    Ma, A.2    Cheng, H.L.3    Alt, F.W.4
  • 35
    • 0028051551 scopus 로고
    • Role of TCR zeta chain in T cell development and selection
    • Shores, E.W., Huang, K., Tran, T., Lee, E., Grinberg, A., and Love, P.E. (1994). Role of TCR zeta chain in T cell development and selection. Science 266, 1047-1050.
    • (1994) Science , vol.266 , pp. 1047-1050
    • Shores, E.W.1    Huang, K.2    Tran, T.3    Lee, E.4    Grinberg, A.5    Love, P.E.6
  • 36
    • 0033579813 scopus 로고    scopus 로고
    • T cell receptor (TCR) antagonism without a negative signal: Evidence from T cell hybridomas expressing two independent TCRs
    • Stotz, S.H., Bolliger, L., Carbone, F.R., and Palmer, E. (1999). T cell receptor (TCR) antagonism without a negative signal: Evidence from T cell hybridomas expressing two independent TCRs. J. Exp. Med. 189, 253-264.
    • (1999) J. Exp. Med. , vol.189 , pp. 253-264
    • Stotz, S.H.1    Bolliger, L.2    Carbone, F.R.3    Palmer, E.4
  • 37
    • 0031172162 scopus 로고    scopus 로고
    • Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition
    • Valitutti, S., and Lanzavecchia, A. (1997). Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition. Immunol. Today 18, 299-304.
    • (1997) Immunol. Today , vol.18 , pp. 299-304
    • Valitutti, S.1    Lanzavecchia, A.2
  • 38
    • 0029037210 scopus 로고
    • Serial triggering of many T-cell receptors by a few peptide-MHC complexes
    • Valitutti, S., Muller, S., Cella, M., Padovan, E., and Lanzavecchia, A. (1995). Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375, 148-151.
    • (1995) Nature , vol.375 , pp. 148-151
    • Valitutti, S.1    Muller, S.2    Cella, M.3    Padovan, E.4    Lanzavecchia, A.5
  • 39
    • 0029797674 scopus 로고    scopus 로고
    • Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates
    • Valitutti, S., Muller, S., Dessing, M., and Lanzavecchia, A. (1996). Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur. J. Immunol. 26, 2012-2016.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2012-2016
    • Valitutti, S.1    Muller, S.2    Dessing, M.3    Lanzavecchia, A.4
  • 40
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T cell receptor number and tunable thresholds
    • Viola, A., and Lanzavecchia, A. (1996). T cell activation determined by T cell receptor number and tunable thresholds. Science 273, 104-106.
    • (1996) Science , vol.273 , pp. 104-106
    • Viola, A.1    Lanzavecchia, A.2
  • 41
    • 0033525759 scopus 로고    scopus 로고
    • EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake
    • Wilde, A., Beattie, E.C., Lem, L., Riethof, D.A., Liu, S.H., Mobley, W.C., Soriano, P., and Brodsky, F.M. (1999). EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96, 677-687.
    • (1999) Cell , vol.96 , pp. 677-687
    • Wilde, A.1    Beattie, E.C.2    Lem, L.3    Riethof, D.A.4    Liu, S.H.5    Mobley, W.C.6    Soriano, P.7    Brodsky, F.M.8
  • 42
    • 0020628152 scopus 로고
    • Tolerance of T-cell clones is associated with membrane antigen changes
    • Zanders, E.D., Lamb, J.R., Feldmann, M., Green, N., and Beverley, P.C. (1983). Tolerance of T-cell clones is associated with membrane antigen changes. Nature 303, 625-627.
    • (1983) Nature , vol.303 , pp. 625-627
    • Zanders, E.D.1    Lamb, J.R.2    Feldmann, M.3    Green, N.4    Beverley, P.C.5


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