CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 39, 2010, Pages 16916-16921

  Artyomov, Maxim N ^a,b   Lis, Mieszko ^c   Devadas, Srinivas ^c   Davis, Mark M ^d   Chakraborty, Arup K ^a,e,f  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Massachusetts Institute of Technology Cambridge   (United States)

^f HARVARD UNIVERSITY   (United States)

Author keywords

Computation; Coreceptors; Diffusion; Stochastic process; T cell activation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; GENE TARGETING; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; RECEPTOR BINDING; ANIMAL; ANTIGEN PRESENTING CELL; CHEMISTRY; ENZYMOLOGY; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PROTEIN TRANSPORT; T LYMPHOCYTE;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD4; ANTIGENS, CD8; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MAJOR HISTOCOMPATIBILITY COMPLEX; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 78049266750     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1010568107     Document Type: Article

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