Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells

Journal of Experimental Medicine

Volumn 188, Issue 8, 1998, Pages 1473-1484

  Delon, Jérôme ^a   Bercovici, Nadège ^a,b   Raposo, Graça ^a   Liblau, Roland ^a,b   Trautmann, Alain ^a,c  

^a CNRS   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c Laboratoire d'Immunologie Cellulaire et Tissulaire CNRS URA 625   (France)

Author keywords

B cells; Ca2+ imaging; Contact zone; Dendritic cells; T cells

Indexed keywords

ANTIGEN; CALCIUM ION; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CELL ADHESION; CONTROLLED STUDY; DENDRITIC CELL; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HELPER CELL; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; B-LYMPHOCYTES; CALCIUM; CELL COMMUNICATION; DENDRITIC CELLS; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 0032547759     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.8.1473     Document Type: Article

References (50)

1. Steinman, R.M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271-296.
2. Inaba, K., and R.M. Steinman. 1986. Accessory cell-T lymphocyte interactions. Antigen-dependent and -independent clustering. J. Exp. Med. 163:247-261.
3. Metlay, J.P., E. Pure, and R.M. Steinman. 1989. Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction. J. Exp. Med. 169:239-254.
4. + T cells in vitro: characteristics and antigen-presenting cell requirements. J. Exp. Med. 176: 1431-1437.
5. Young, J.W., and K. Inaba. 1996. Dendritic cells as adjuvants for class I major histocompatibihty complex-restricted antitumor immunity. J. Exp. Med. 183:7-11.
6. Girolomoni, G., and P. Ricciardi-Castagnoli. 1997. Dendritic cells hold promise for immunotherapy. Immunol. Today. 18:102-104.
7. Hsu, F.J., C. Benike, F. Fagnoni, T.M. Liles, D. Czerwinski, B. Taidi, E.G. Engleman, and R. Levy. 1996. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat. Med. 2:52-58.
8. Inaba, K., and R.M. Steinman. 1987. Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed lymphocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes J. Exp. Med. 165:1403-1417.
9. + T cells. Eur. J. Immunol. 25:2285-2294.
10. Harding, C.V., and E.R. Unanue. 1990. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature. 346:574-576.
11. Demotz, S., H.M. Grey, and A. Sette. 1990. The minimal number of class II MHC-antigen complexes needed for T cell activation. Science. 249:1028-1030.
12. Vitiello, A., T.A. Potter, and L.A. Sherman. 1990. The role of β2-microglobulin in peptide binding by class I molecules. Science. 250:1423-1426.
13. Kageyama, S., T.J. Tsomides, Y. Sykulev, and H.N. Eisen. 1995. Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J. Immunol. 154:567-576.
14. Scott, B., R.S. Liblau, S. Degerman, A.L. Marconi, A.J. Caton, H.O. McDevitt, and D. Lo. 1994. A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity. 1:72-83.
15. Liblau, R.S., R. Tisch, K. Shokat, N. Dumont, X.-D. Yang, and H.O. McDevitt. 1996. Intravenous injection of high-dose soluble antigen induces thymic and peripheral T cell apoptosis. Proc. Natl. Acad. Sci. USA. 93:3031-3036.
16. 2+ response. Eur.J. Immunol. 28:716-729.
17. Cosgrove, D., D. Gray, A. Dierich, J. Kaufman, M. Lemeur, C. Benoist, and D. Mathis. 1991. Mice lacking MHC class II molecules. Cell. 66:1051-1066.
18. Swiggard, W.J., R.M. Nonacs, M.D. Witmer-Pack, R.M. Steinman, and K. Inaba. 1992. Enrichment of dendritic cells by plastic adherence and EA resetting. In Current Protocols in Immunology. J.E. Coligan, A.M. Kruisbeek, D.H. Marguiles, E.M. Shevach, and W. Strober, editors. John Wiley & Sons, New York, 3.7.1.
19. Andrew, S.M., and J.A. Titus. 1991. Purification and fragmentation of antibodies. In Current Protocols in Immunology. J.E. Coligan, A.M. Kruisbeek, D.H. Marguiles, E.M. Shevach, and W. Strober, editors. John Wiley & Sons, New York. 2.7.1.
20. Renard, V., J. Delon, I.F. Luescher, B. Malissen, E. Vivier, and A. Trautmann. 1996. The CD8β polypeptide is required for the recognition of an altered peptide ligand as an agonist. Eur. J. Immunol. 26:2999-3007.
21. Steinman, R.M., G. Kaplan, M.D. Witmer, and Z.A. Cohn. 1979. Identification of a novel cell type in peripheral organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J. Exp. Med. 149:1-16.
22. Crowley, M.T., K. Inaba, M.D. Witmer, S. Gezelter, and R.M. Steinman. 1990. Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen. J. Immunol. Methods. 133:55-66.
23. Metlay, J.P., M.D. Witmer-Pack, R. Agger, M.T. Crowley, D. Lawless, and R.M. Steinman. 1990. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J. Exp. Med. 171: 1753-1771.
24. Johnson, P., L. Greenbaum, K. Bottomly, and I.S. Trowbridge. 1989. Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J. Exp. Med. 169:1179-1184.
25. June, C.H., J.A. Bluestone, L.M. Nadler, and C.B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today. 15:321-331.
26. Iezzi, G., K. Karjalainen, and A. Lanzavecchia. 1998. The duration of antigenic stimulation determines the fate of naive and effector cells. Immunity. 8:89-95.
27. Cella, M., A. Engering, V. Pinet, J. Pieters, and A. Lanzavecchia. 1997. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature. 388:782-787.
28. Bhardwaj, N., J.W. Young, A.J. Nisanian, J. Baggers, and R.M. Steinman. 1993. Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses. J. Exp. Med. 178:633-642.
29. Sykulev, Y., M. Joo, I. Vturina, T.J. Tsomides, and H.N. Eisen. 1996. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity. 4:565-571.
30. Zhong, G., C. Reis e Sousa, and R.N. Germain. 1997. Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro. J. Exp. Med. 186:673-682.
31. 2+ concentration optimal for T cell activation is quite different after ionomycin or CD3 stimulation. Pflügers Arch. 429:546-554.
32. Negulescu, P.A., N. Shastri, and D. Cahalan. 1994. Intracellular calcium dependence of gene expression in single T lymphocytes. Proc. Natl. Acad. Sci. USA. 91:2873-2877.
33. Rabinowitz, J.D., C. Beeson, C. Wülfing, K. Tate, P. Allen, M.M. Davis, and H.M. McConnell. 1996. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity. 5:125-135.
34. Valitutti, S., S. Müller, M. Dessing, and A. Lanzavecchia. 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183:1917-1921.
35. Bachmann, M.F., A. Oxenius, D.E. Speiser, S. Mariathasan, H. Hengartner, R.M. Zinkernagel, and P.S. Ohashi. 1997. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. Eur. J. Immunol. 27:2195-2203.
36. Inaba, K., N. Romani, and R.M. Steinman. 1989. An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells. J. Exp. Med. 170:527-542.
37. Green, J., and R. Jotte. 1985. Interactions between T helper cells and dendritic cells during the rat mixed leukocyte reaction. J. Exp. Med. 162:1546-1560.
38. Davis, M.M., and Y. Chien. 1993. Topology and affinity of T-cell receptor mediated recognition of peptide-MHC complexes. Curr. Opin. Immunol. 5:45-49.
39. Pagès, F., M. Ragueneau, R. Rottapel, A. Truneh, J. Nunes, J. Imbert, and D. Olive. 1994. Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature. 369:327-329.
40. + splenic T cells after CD28 receptor ligation.J. Immunol. 154:985-997.
41. Ohnishi, H., J.A. Ledbetter, S.B. Kanner, P.S. Linsley, T. Tanaka, A.M. Geller, and M. Kotb. 1995. CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses. J. Immunol. 154:3180-3193.
42. Pardi, R., J.R. Bender, C. Dettori, E. Giannazza, and E.G. Engleman. 1989. Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets. J. Immunol. 143:3157-3166.
43. 2-integrin LFA-51 signaling through phospholipase C-γ1 activation. Proc. Natl. Acad. Sci. USA. 90:7099-7103.
44. 2+ levels in the regulation of CD11a/CD18 mediated cell adhesion. Cell Adhes. Commun. 1:21-32.
45. 2+ mobilization upon CD2-mediated T cell activation. Biophys. J. 68:459-470.
46. + T cells, but affeet their long-term life span. Immunity. 5:217-228.
47. Kirberg, J., A. Berns, and H. von Boehmer. 1997. Peripheral T cell survival requires continual ligation of the T eell receptor to major histocompatibility complex-encoded molecules. J. Exp. Med. 186:1269-1275.
48. Tanchot, C., F.A. Lemonnier, B. Pérarnau, A.A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science. 276: 2057-2062.
49. Brocker, T. 1997. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J. Exp. Med. 186:1223-1232.
50. + cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists. Eur. J. Immunol. 27:3414-3419.