-
1
-
-
55849090253
-
Hunter to gatherer and back: Immunological synapses and kinapses as variations on the theme of amoeboid locomotion
-
Dustin ML (2008) Hunter to gatherer and back: Immunological synapses and kinapses as variations on the theme of amoeboid locomotion. Annu Rev Cell Dev Biol 24: 577-596.
-
(2008)
Annu Rev Cell Dev Biol
, vol.24
, pp. 577-596
-
-
Dustin, M.L.1
-
3
-
-
18744390475
-
Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activation
-
Das V, et al. (2002) Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activation. Immunol Rev 189:123-135.
-
(2002)
Immunol Rev
, vol.189
, pp. 123-135
-
-
Das, V.1
-
4
-
-
0020365635
-
Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells
-
Geiger B, Rosen D, Berke G (1982) Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells. J Cell Biol 95: 137-143.
-
(1982)
J Cell Biol
, vol.95
, pp. 137-143
-
-
Geiger, B.1
Rosen, D.2
Berke, G.3
-
5
-
-
0021714772
-
Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells
-
Kupfer A, Dennert G (1984) Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells. J Immunol 133:2762-2766.
-
(1984)
J Immunol
, vol.133
, pp. 2762-2766
-
-
Kupfer, A.1
Dennert, G.2
-
6
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
7
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
Grakoui A, et al. (1999) The immunological synapse: A molecular machine controlling T cell activation. Science 285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
-
8
-
-
26444452661
-
-
Gaus K, Chklovskaia E, Fazekas de St Groth B, JessupW, Harder T (2005) Condensation of the plasma membrane at the site of T lymphocyte activation. J Cell Biol 171: 121-131.
-
Gaus K, Chklovskaia E, Fazekas de St Groth B, JessupW, Harder T (2005) Condensation of the plasma membrane at the site of T lymphocyte activation. J Cell Biol 171: 121-131.
-
-
-
-
9
-
-
0034714184
-
Differential clustering of CD4 and CD3zeta during T cell recognition
-
Krummel MF, Sjaastad MD, Wülfing C, Davis MM (2000) Differential clustering of CD4 and CD3zeta during T cell recognition. Science 289:1349-1352.
-
(2000)
Science
, vol.289
, pp. 1349-1352
-
-
Krummel, M.F.1
Sjaastad, M.D.2
Wülfing, C.3
Davis, M.M.4
-
10
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
Bunnell SC, et al. (2002) T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol 158:1263-1275.
-
(2002)
J Cell Biol
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
-
11
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
Campi G, Varma R, Dustin ML (2005) Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J ExpMed 202:1031-1036.
-
(2005)
J ExpMed
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
12
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
Yokosuka T, et al. (2005) Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat Immunol 6:1253-1262.
-
(2005)
Nat Immunol
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
-
13
-
-
20444404267
-
Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells
-
Douglass AD, Vale RD (2005) Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 121:937-950.
-
(2005)
Cell
, vol.121
, pp. 937-950
-
-
Douglass, A.D.1
Vale, R.D.2
-
14
-
-
0037716822
-
The diversity of immunological synapses
-
Trautmann A, Valitutti S (2003) The diversity of immunological synapses. Curr Opin Immunol 15:249-254.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 249-254
-
-
Trautmann, A.1
Valitutti, S.2
-
15
-
-
34447339202
-
Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse
-
Reichardt P, et al. (2007) Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse. Blood 110:1519-1529.
-
(2007)
Blood
, vol.110
, pp. 1519-1529
-
-
Reichardt, P.1
-
16
-
-
66149112471
-
Spatiotemporal patterning during T cell activation is highly diverse
-
Singleton KL, et al. (2009) Spatiotemporal patterning during T cell activation is highly diverse. Sci Signal 2:ra15.
-
(2009)
Sci Signal
, vol.2
-
-
Singleton, K.L.1
-
17
-
-
20844439947
-
Multifocal structure of the T cell - dendritic cell synapse
-
Brossard C, et al. (2005) Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol 35:1741-1753.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1741-1753
-
-
Brossard, C.1
-
18
-
-
0036063264
-
Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation
-
Hailman E, Burack WR, Shaw AS, Dustin ML, Allen PM (2002) Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity 16:839-848.
-
(2002)
Immunity
, vol.16
, pp. 839-848
-
-
Hailman, E.1
Burack, W.R.2
Shaw, A.S.3
Dustin, M.L.4
Allen, P.M.5
-
19
-
-
0037036114
-
Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
-
Stoll S, Delon J, Brotz TM, Germain RN (2002) Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296:1873-1876.
-
(2002)
Science
, vol.296
, pp. 1873-1876
-
-
Stoll, S.1
Delon, J.2
Brotz, T.M.3
Germain, R.N.4
-
20
-
-
33748549010
-
In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain
-
Barcia C, et al. (2006) In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain. J Exp Med 203:2095-2107.
-
(2006)
J Exp Med
, vol.203
, pp. 2095-2107
-
-
Barcia, C.1
-
21
-
-
0035313266
-
Cutting edge: In vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells
-
Reichert P, Reinhardt RL, Ingulli E, Jenkins MK (2001) Cutting edge: In vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells. J Immunol 166: 4278-4281.
-
(2001)
J Immunol
, vol.166
, pp. 4278-4281
-
-
Reichert, P.1
Reinhardt, R.L.2
Ingulli, E.3
Jenkins, M.K.4
-
22
-
-
0036794559
-
Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo
-
McGavern DB, Christen U, Oldstone MB (2002) Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo. Nat Immunol 3:918-925.
-
(2002)
Nat Immunol
, vol.3
, pp. 918-925
-
-
McGavern, D.B.1
Christen, U.2
Oldstone, M.B.3
-
23
-
-
35148819683
-
In situ imaging of the endogenous CD8 T cell response to infection
-
Khanna KM, McNamara JT, Lefrançois L (2007) In situ imaging of the endogenous CD8 T cell response to infection. Science 318:116-120.
-
(2007)
Science
, vol.318
, pp. 116-120
-
-
Khanna, K.M.1
McNamara, J.T.2
Lefrançois, L.3
-
24
-
-
0037036142
-
Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
-
Miller MJ, Wei SH, Parker I, Cahalan MD (2002) Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296:1869-1873.
-
(2002)
Science
, vol.296
, pp. 1869-1873
-
-
Miller, M.J.1
Wei, S.H.2
Parker, I.3
Cahalan, M.D.4
-
25
-
-
22944490227
-
The c-SMAC: Sorting it all out (or in)
-
Lin J, Miller MJ, Shaw AS (2005) The c-SMAC: Sorting it all out (or in). J Cell Biol 170: 177-182.
-
(2005)
J Cell Biol
, vol.170
, pp. 177-182
-
-
Lin, J.1
Miller, M.J.2
Shaw, A.S.3
-
26
-
-
42649101626
-
Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs
-
Cahalan MD, Parker I (2008) Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol 26: 585-626.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 585-626
-
-
Cahalan, M.D.1
Parker, I.2
-
27
-
-
50249144544
-
T-cell activation by dendritic cells in the lymph node: Lessons from the movies
-
Bousso P (2008) T-cell activation by dendritic cells in the lymph node: Lessons from the movies. Nat Rev Immunol 8:675-684.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 675-684
-
-
Bousso, P.1
-
28
-
-
27844553451
-
Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node
-
Cahalan MD, Parker I (2005) Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node. Semin Immunol 17:442-451.
-
(2005)
Semin Immunol
, vol.17
, pp. 442-451
-
-
Cahalan, M.D.1
Parker, I.2
-
29
-
-
38949197102
-
T-cell activation through immunological synapses and kinapses
-
Dustin ML (2008) T-cell activation through immunological synapses and kinapses. Immunol Rev 221:77-89.
-
(2008)
Immunol Rev
, vol.221
, pp. 77-89
-
-
Dustin, M.L.1
-
30
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE (1998) LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:83-92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
31
-
-
0032142953
-
LAT palmitoylation: Its essential role inmembrane microdomain targeting and tyrosine phosphorylation during T cell activation
-
ZhangW, Trible RP, Samelson LE (1998) LAT palmitoylation: Its essential role inmembrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 9: 239-246.
-
(1998)
Immunity
, vol.9
, pp. 239-246
-
-
Zhang, W.1
Trible, R.P.2
Samelson, L.E.3
-
32
-
-
21444450396
-
Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells
-
Shogomori H, et al. (2005) Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells. J Biol Chem 280:18931-18942.
-
(2005)
J Biol Chem
, vol.280
, pp. 18931-18942
-
-
Shogomori, H.1
-
33
-
-
11144354114
-
Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment
-
Bonello G, et al. (2004) Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment. J Cell Sci 117:1009-1016.
-
(2004)
J Cell Sci
, vol.117
, pp. 1009-1016
-
-
Bonello, G.1
-
34
-
-
33748366578
-
Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1
-
Houtman JC, et al. (2006) Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1. Nat Struct Mol Biol 13:798-805.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 798-805
-
-
Houtman, J.C.1
-
35
-
-
0347717903
-
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
-
Mempel TR, Henrickson SE, Von Andrian UH (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427:154-159.
-
(2004)
Nature
, vol.427
, pp. 154-159
-
-
Mempel, T.R.1
Henrickson, S.E.2
Von Andrian, U.H.3
-
36
-
-
5444229324
-
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes
-
Miller MJ, Safrina O, Parker I, Cahalan MD (2004) Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med 200:847-856.
-
(2004)
J Exp Med
, vol.200
, pp. 847-856
-
-
Miller, M.J.1
Safrina, O.2
Parker, I.3
Cahalan, M.D.4
-
37
-
-
34248356001
-
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion
-
Garcia Z, et al. (2007) Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion. Proc Natl Acad Sci USA 104:4553-4558.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4553-4558
-
-
Garcia, Z.1
-
38
-
-
16544383331
-
Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity
-
Hugues S, et al. (2004) Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity. Nat Immunol 5:1235-1242.
-
(2004)
Nat Immunol
, vol.5
, pp. 1235-1242
-
-
Hugues, S.1
-
39
-
-
42449110816
-
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
-
Sinclair LV, et al. (2008) Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol 9:513-521.
-
(2008)
Nat Immunol
, vol.9
, pp. 513-521
-
-
Sinclair, L.V.1
-
40
-
-
34548658855
-
Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node
-
Wei SH, et al. (2007) Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node. J Immunol 179:1586-1594.
-
(2007)
J Immunol
, vol.179
, pp. 1586-1594
-
-
Wei, S.H.1
-
41
-
-
38949191290
-
Decoding the dynamics of T cell-dendritic cell interactions in vivo
-
Celli S, Garcia Z, Beuneu H, Bousso P (2008) Decoding the dynamics of T cell-dendritic cell interactions in vivo. Immunol Rev 221:182-187.
-
(2008)
Immunol Rev
, vol.221
, pp. 182-187
-
-
Celli, S.1
Garcia, Z.2
Beuneu, H.3
Bousso, P.4
-
42
-
-
0037188522
-
CD2 molecules redistribute to the uropod during T cell scanning: Implications for cellular activation and immune surveillance
-
Tibaldi EV, Salgia R, Reinherz EL (2002) CD2 molecules redistribute to the uropod during T cell scanning: Implications for cellular activation and immune surveillance. Proc Natl Acad Sci USA 99:7582-7587.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7582-7587
-
-
Tibaldi, E.V.1
Salgia, R.2
Reinherz, E.L.3
-
43
-
-
0035859925
-
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization
-
Gómez-Móuton C, et al. (2001) Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization. Proc Natl Acad Sci USA 98: 9642-9647.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9642-9647
-
-
Gómez-Móuton, C.1
-
44
-
-
0031903617
-
CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion
-
Friedl P, Entschladen F, Conrad C, Niggemann B, Zänker KS (1998) CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion. Eur J Immunol 28:2331-2343.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2331-2343
-
-
Friedl, P.1
Entschladen, F.2
Conrad, C.3
Niggemann, B.4
Zänker, K.S.5
-
45
-
-
0030785793
-
Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis
-
Nieto M, et al. (1997) Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis. J Exp Med 186:153-158.
-
(1997)
J Exp Med
, vol.186
, pp. 153-158
-
-
Nieto, M.1
-
46
-
-
0345257150
-
Lytic versus stimulatory synapse in cytotoxic T lymphocyte/ target cell interaction: Manifestation of a dual activation threshold
-
Faroudi M, et al. (2003) Lytic versus stimulatory synapse in cytotoxic T lymphocyte/ target cell interaction: manifestation of a dual activation threshold. Proc Natl Acad Sci USA 100:14145-14150.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14145-14150
-
-
Faroudi, M.1
-
47
-
-
21844450539
-
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
-
Okada T, et al. (2005) Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol 3:e150.
-
(2005)
PLoS Biol
, vol.3
-
-
Okada, T.1
-
48
-
-
4644323006
-
A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo
-
Gunzer M, et al. (2004) A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo. Blood 104:2801-2809.
-
(2004)
Blood
, vol.104
, pp. 2801-2809
-
-
Gunzer, M.1
-
49
-
-
53649107278
-
SAP-controlled T-B cell interactions underlie germinal centre formation
-
Qi H, Cannons JL, Klauschen F, Schwartzberg PL, Germain RN (2008) SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 455:764-769.
-
(2008)
Nature
, vol.455
, pp. 764-769
-
-
Qi, H.1
Cannons, J.L.2
Klauschen, F.3
Schwartzberg, P.L.4
Germain, R.N.5
-
50
-
-
34249013684
-
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse
-
Sims TN, et al. (2007) Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell 129:773-785.
-
(2007)
Cell
, vol.129
, pp. 773-785
-
-
Sims, T.N.1
-
51
-
-
50049109579
-
Interstitial leukocyte migration and immune function
-
Friedl P, Weigelin B (2008) Interstitial leukocyte migration and immune function. Nat Immunol 9:960-969.
-
(2008)
Nat Immunol
, vol.9
, pp. 960-969
-
-
Friedl, P.1
Weigelin, B.2
-
52
-
-
0035887927
-
CD4 promotes breadth in the TCR repertoire
-
Wang Q, et al. (2001) CD4 promotes breadth in the TCR repertoire. J Immunol 167: 4311-4320.
-
(2001)
J Immunol
, vol.167
, pp. 4311-4320
-
-
Wang, Q.1
-
53
-
-
0034046944
-
Plat-E: An efficient and stable system for transient packaging of retroviruses
-
Morita S, Kojima T, Kitamura T (2000) Plat-E: An efficient and stable system for transient packaging of retroviruses. Gene Ther 7:1063-1066.
-
(2000)
Gene Ther
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
|